List of works - Anna Pastore

A new simple and rapid LC-ESI-MS/MS method for quantification of plasma oxysterols as dimethylaminobutyrate esters. Its successful use for the diagnosis of Niemann-Pick type C disease

scientific article

Actin glutathionylation increases in fibroblasts of patients with Friedreich's ataxia: a potential role in the pathogenesis of the disease

scientific article published on 11 August 2003

Activation of the transcription factor EB rescues lysosomal abnormalities in cystinotic kidney cells

scientific article published on April 2016

All glutathione forms are depleted in blood of obese and type 1 diabetic children

Altered mTOR signalling in nephropathic cystinosis

scientific article

Analysis of glutathione: implication in redox and detoxification

scientific article

Antioxidant enzymes in blood of patients with Friedreich's ataxia.

scientific article published on May 2002

Brown-Vialetto-van Laere and Fazio-Londe overlap syndromes: a clinical, biochemical and genetic study

scientific article published on 21 July 2012

COQ2 nephropathy: a newly described inherited mitochondriopathy with primary renal involvement

scientific article

Characterization of a new trabectedin-resistant myxoid liposarcoma cell line that shows collateral sensitivity to methylating agents.

scientific article

Colorimetric and Fluorometric Assays of Glutathione Transferase Based on 7-Chloro-4-nitrobenzo-2-oxa-1,3-diazole

scientific article published on 01 May 1994

Common mutation in methylenetetrahydrofolate reductase. Correlation with homocysteine and other risk factors for vascular disease

scientific article published in August 1998

Conformational States of Human Placental Glutathione Transferase as Probed by Limited Proteolysis

scientific article published on 01 July 1993

Creatine metabolism in urea cycle defects

scientific article published on 30 May 2012

Cystinosin-LKG rescues cystine accumulation and decreases apoptosis rate in cystinotic proximal tubular epithelial cells

scientific article published on 22 September 2016

Cystinosis (ctns) zebrafish mutant shows pronephric glomerular and tubular dysfunction.

scientific article

Cystinuria in children and young adults: success of monitoring free-cystine urine levels

scientific article published on 11 August 2007

Detection of iron deficiency in children with Down syndrome

scientific article published on 16 August 2019

Determination of blood total, reduced, and oxidized glutathione in pediatric subjects.

scientific article

Determination of glutathionyl-hemoglobin in human erythrocytes by cation-exchange high-performance liquid chromatography

scientific article published in January 2003

Determination of superoxide dismutase and glutathione peroxidase activities in blood of healthy pediatric subjects

scientific article published in August 2002

Drastic reduction of piperacillin-tazobactam concentrations in an in-vitro model of continuous venovenous hemofiltration: proposal of an innovative modality of administration to maintain them at constant concentration

scientific article

EPI-743 reverses the progression of the pediatric mitochondrial disease--genetically defined Leigh Syndrome.

scientific article

Effect of protein glutathionylation on neuronal cytoskeleton: a potential link to neurodegeneration

scientific article published on 6 June 2011

Effects of folic acid before and after vitamin B12 on plasma homocysteine concentrations in hemodialysis patients with known MTHFR genotypes

scientific article published in January 2006

Effects of levosimendan on mitochondrial function in patients with septic shock: a randomized trial

scientific article

Emodin prevents intrahepatic fat accumulation, inflammation and redox status imbalance during diet-induced hepatosteatosis in rats

scientific article

Endo-lysosomal dysfunction in human proximal tubular epithelial cells deficient for lysosomal cystine transporter cystinosin

scientific article

Erythrocyte glutathione transferase activity: a possible early biomarker for blood toxicity in uremic diabetic patients.

scientific article published on 2 July 2013

Erythrocyte glutathione transferase: a potential new biomarker in chronic kidney diseases which correlates with plasma homocysteine

scientific article published on 08 October 2011

Evaluation of carbohydrate-cysteamine thiazolidines as pro-drugs for the treatment of cystinosis

scientific article published on 18 December 2016

Extracorporeal dialysis in neonatal hyperammonemia: modalities and prognostic indicators.

scientific article published in November 2001

Frataxin silencing alters microtubule stability in motor neurons: implications for Friedreich's ataxia.

scientific article published on 11 August 2016

Frataxin silencing inactivates mitochondrial Complex I in NSC34 motoneuronal cells and alters glutathione homeostasis

scientific article published on 4 April 2014

Fully automated assay for total homocysteine, cysteine, cysteinylglycine, glutathione, cysteamine, and 2-mercaptopropionylglycine in plasma and urine.

scientific article published on April 1998

GSSG-mediated Complex I defect in isolated cardiac mitochondria.

scientific article

Gender-related effects on urine L-cystine metastability.

scientific article published on 11 December 2013

Glutathione S-transferase P1-1 as a target for mesothelioma treatment.

scientific article published on 24 December 2012

Glutathione imbalance in patients with X-linked adrenoleukodystrophy ⬇️

scientific article published on May 22, 2013

Glutathione in blood of patients with Friedreich's ataxia.

scientific article published in November 2001

Glutathione metabolism and antioxidant enzymes in children with Down syndrome

scientific article published in May 2003

Glutathione metabolism and antioxidant enzymes in patients affected by nonalcoholic steatohepatitis

scientific article published in May 2005

Glutathione metabolism in cobalamin deficiency type C (cblC).

scientific article

Glutathione: a redox signature in monitoring EPI-743 therapy in children with mitochondrial encephalomyopathies

scientific article

Glutathionylation of p65NF-kappaB correlates with proliferating/apoptotic hepatoma cells exposed to pro- and anti-oxidants

scientific article

High concentrations of H2O2 trigger hypertrophic cascade and phosphatase and tensin homologue (PTEN) glutathionylation in H9c2 cardiomyocytes

scientific article published on 7 January 2016

High performance liquid chromatographic determination of plasma free and total tazobactam and piperacillin.

scientific article

Homocysteine, cysteine, folate and vitamin B₁₂ status in type 2 diabetic patients with chronic kidney disease.

scientific article published on 6 August 2014

Impaired activity of the gamma-glutamyl cycle in nephropathic cystinosis fibroblasts

scientific article published in February 2006

Influence of dialysis techniques and alternate vitamin supplementation on homocysteine levels in patients with known MTHFR genotypes

scientific article published on 21 March 2014

Lack of association between carotid intima-media thickness and methylenetetrahydrofolate reductase gene polymorphism or serum homocysteine in non-insulin-dependent diabetes mellitus

scientific article

Long-term outcome of nephropathic cystinosis: a 20-year single-center experience

scientific article published on 29 August 2010

Long-term renal function in heart transplant children on cyclosporine treatment

scientific article published on 21 February 2006

Modulation of CTNS gene expression by intracellular thiols

scientific article

Myosin as a potential redox-sensor: an in vitro study.

scientific article

Nitrosylation of human glutathione transferase P1-1 with dinitrosyl diglutathionyl iron complex in vitro and in vivo

scientific article

Nrf2-Inducers Counteract Neurodegeneration in Frataxin-Silenced Motor Neurons: Disclosing New Therapeutic Targets for Friedreich's Ataxia

scientific article published on 18 October 2017

Optimizing the dose of hydroxocobalamin in cobalamin C (cblC) defect.

scientific article published on 29 May 2013

Pediatric reference intervals for muscle coenzyme Q(10).

scientific article published in October 2012

Pitfalls in the quantitative imaging of glutathione in living cells

scientific article published on 23 April 2018

Plasma levels of homocysteine and cysteine increased in pediatric NAFLD and strongly correlated with severity of liver damage.

scientific article

Protein glutathionylation in cardiovascular diseases

scientific article

Protein glutathionylation in cellular compartments: A constitutive redox signal

Protein glutathionylation in human central nervous system: potential role in redox regulation of neuronal defense against free radicals

scientific article published in February 2006

Pyroglutamic aciduria and nephropathic cystinosis

scientific article published on 01 May 1999

Rapid determination of mycophenolic acid in plasma by reversed-phase high-performance liquid chromatography

scientific article

Redox homeostasis and posttranslational modifications/activity of phosphatase and tensin homolog in hepatocytes from rats with diet-induced hepatosteatosis

scientific article published on 30 March 2011

Renal hemodynamic effect of tacrolimus in renal transplanted children

scientific article

Reverse-phase high-performance liquid chromatography for the simultaneous determination of sildenafil and N-desmethyl sildenafil in plasma of children.

scientific article

Role of GST P1-1 in mediating the effect of etoposide on human neuroblastoma cell line Sh-Sy5y

scientific article published on January 2002

S-Glutathionylation signaling in cell biology: Progress and prospects ⬇️

scientific article published on March 30, 2012

Selective adsorption of homocysteine using an HFR-ON LINE technique

scientific article

Semiautomated method for determination of cystine concentration in polymorphonuclear leukocytes

scientific article published on 01 April 2000

Serum homocysteine, MTHFR gene polymorphism, and carotid intimal-medial thickness in NIDDM subjects

scientific article

Serum homocysteine, methylenetetrahydrofolate reductase gene polymorphism and cardiovascular disease in heterozygous familial hypercholesterolemia

scientific article

Simultaneous determination of ubiquinol and ubiquinone in skeletal muscle of pediatric patients

scientific article published on 7 March 2005

Studying nonobstructive azoospermia in cystinosis: histologic examination of testes and epididymis and sperm analysis in a Ctns−/− mouse model

scientific article published on 10 May 2012

Susceptibility of isolated myofibrils to in vitro glutathionylation: Potential relevance to muscle functions

scientific article

Systemic Redox Biomarkers in Neurodegenerative Diseases

scientific article published on January 2015

Targeting oxidative stress improves disease outcomes in a rat model of acquired epilepsy.

scientific article published on 30 May 2017

The fine-tuning of TRAF2-GSTP1-1 interaction: effect of ligand binding and in situ detection of the complex

scientific article

The proteome of cblC defect: in vivo elucidation of altered cellular pathways in humans

scientific article published on 14 January 2015

The use of muscle biopsy in the diagnosis of undefined ataxia with cerebellar atrophy in children.

scientific article published on 27 August 2011

Transcriptional and Posttranscriptional Regulation of the CTNS Gene ⬇️

scientific article published on August 1, 2011

Treatment of doxorubicin-resistant MCF7/Dx cells with nitric oxide causes histone glutathionylation and reversal of drug resistance

scientific article

[Hyperhomocysteinemia and alternate vitamin supplementation]

scientific article published on 01 January 2007

List of works by Anna Pastore

A new simple and rapid LC-ESI-MS/MS method for quantification of plasma oxysterols as dimethylaminobutyrate esters. Its successful use for the diagnosis of Niemann-Pick type C disease

Actin glutathionylation increases in fibroblasts of patients with Friedreich's ataxia: a potential role in the pathogenesis of the disease

Activation of the transcription factor EB rescues lysosomal abnormalities in cystinotic kidney cells

All glutathione forms are depleted in blood of obese and type 1 diabetic children

Altered mTOR signalling in nephropathic cystinosis

Analysis of glutathione: implication in redox and detoxification

Antioxidant enzymes in blood of patients with Friedreich's ataxia.

Brown-Vialetto-van Laere and Fazio-Londe overlap syndromes: a clinical, biochemical and genetic study

COQ2 nephropathy: a newly described inherited mitochondriopathy with primary renal involvement

Characterization of a new trabectedin-resistant myxoid liposarcoma cell line that shows collateral sensitivity to methylating agents.

Colorimetric and Fluorometric Assays of Glutathione Transferase Based on 7-Chloro-4-nitrobenzo-2-oxa-1,3-diazole

Common mutation in methylenetetrahydrofolate reductase. Correlation with homocysteine and other risk factors for vascular disease

Conformational States of Human Placental Glutathione Transferase as Probed by Limited Proteolysis

Creatine metabolism in urea cycle defects

Cystinosin-LKG rescues cystine accumulation and decreases apoptosis rate in cystinotic proximal tubular epithelial cells

Cystinosis (ctns) zebrafish mutant shows pronephric glomerular and tubular dysfunction.

Cystinuria in children and young adults: success of monitoring free-cystine urine levels

Detection of iron deficiency in children with Down syndrome

Determination of blood total, reduced, and oxidized glutathione in pediatric subjects.

Determination of glutathionyl-hemoglobin in human erythrocytes by cation-exchange high-performance liquid chromatography

Determination of superoxide dismutase and glutathione peroxidase activities in blood of healthy pediatric subjects

Drastic reduction of piperacillin-tazobactam concentrations in an in-vitro model of continuous venovenous hemofiltration: proposal of an innovative modality of administration to maintain them at constant concentration

EPI-743 reverses the progression of the pediatric mitochondrial disease--genetically defined Leigh Syndrome.

Effect of protein glutathionylation on neuronal cytoskeleton: a potential link to neurodegeneration

Effects of folic acid before and after vitamin B12 on plasma homocysteine concentrations in hemodialysis patients with known MTHFR genotypes

Effects of levosimendan on mitochondrial function in patients with septic shock: a randomized trial

Emodin prevents intrahepatic fat accumulation, inflammation and redox status imbalance during diet-induced hepatosteatosis in rats

Endo-lysosomal dysfunction in human proximal tubular epithelial cells deficient for lysosomal cystine transporter cystinosin

Erythrocyte glutathione transferase activity: a possible early biomarker for blood toxicity in uremic diabetic patients.

Erythrocyte glutathione transferase: a potential new biomarker in chronic kidney diseases which correlates with plasma homocysteine

Evaluation of carbohydrate-cysteamine thiazolidines as pro-drugs for the treatment of cystinosis

Extracorporeal dialysis in neonatal hyperammonemia: modalities and prognostic indicators.

Frataxin silencing alters microtubule stability in motor neurons: implications for Friedreich's ataxia.

Frataxin silencing inactivates mitochondrial Complex I in NSC34 motoneuronal cells and alters glutathione homeostasis

Fully automated assay for total homocysteine, cysteine, cysteinylglycine, glutathione, cysteamine, and 2-mercaptopropionylglycine in plasma and urine.

GSSG-mediated Complex I defect in isolated cardiac mitochondria.

Gender-related effects on urine L-cystine metastability.

Glutathione S-transferase P1-1 as a target for mesothelioma treatment.

Glutathione imbalance in patients with X-linked adrenoleukodystrophy ⬇️

Glutathione in blood of patients with Friedreich's ataxia.

Glutathione metabolism and antioxidant enzymes in children with Down syndrome

Glutathione metabolism and antioxidant enzymes in patients affected by nonalcoholic steatohepatitis

Glutathione metabolism in cobalamin deficiency type C (cblC).

Glutathione: a redox signature in monitoring EPI-743 therapy in children with mitochondrial encephalomyopathies

Glutathionylation of p65NF-kappaB correlates with proliferating/apoptotic hepatoma cells exposed to pro- and anti-oxidants

High concentrations of H2O2 trigger hypertrophic cascade and phosphatase and tensin homologue (PTEN) glutathionylation in H9c2 cardiomyocytes

High performance liquid chromatographic determination of plasma free and total tazobactam and piperacillin.

Homocysteine, cysteine, folate and vitamin B₁₂ status in type 2 diabetic patients with chronic kidney disease.

Impaired activity of the gamma-glutamyl cycle in nephropathic cystinosis fibroblasts

Influence of dialysis techniques and alternate vitamin supplementation on homocysteine levels in patients with known MTHFR genotypes

Lack of association between carotid intima-media thickness and methylenetetrahydrofolate reductase gene polymorphism or serum homocysteine in non-insulin-dependent diabetes mellitus

Long-term outcome of nephropathic cystinosis: a 20-year single-center experience

Long-term renal function in heart transplant children on cyclosporine treatment

Modulation of CTNS gene expression by intracellular thiols

Myosin as a potential redox-sensor: an in vitro study.

Nitrosylation of human glutathione transferase P1-1 with dinitrosyl diglutathionyl iron complex in vitro and in vivo

Nrf2-Inducers Counteract Neurodegeneration in Frataxin-Silenced Motor Neurons: Disclosing New Therapeutic Targets for Friedreich's Ataxia

Optimizing the dose of hydroxocobalamin in cobalamin C (cblC) defect.

Pediatric reference intervals for muscle coenzyme Q(10).

Pitfalls in the quantitative imaging of glutathione in living cells

Plasma levels of homocysteine and cysteine increased in pediatric NAFLD and strongly correlated with severity of liver damage.

Protein glutathionylation in cardiovascular diseases

Protein glutathionylation in cellular compartments: A constitutive redox signal

Protein glutathionylation in human central nervous system: potential role in redox regulation of neuronal defense against free radicals

Pyroglutamic aciduria and nephropathic cystinosis

Rapid determination of mycophenolic acid in plasma by reversed-phase high-performance liquid chromatography

Redox homeostasis and posttranslational modifications/activity of phosphatase and tensin homolog in hepatocytes from rats with diet-induced hepatosteatosis

Renal hemodynamic effect of tacrolimus in renal transplanted children

Reverse-phase high-performance liquid chromatography for the simultaneous determination of sildenafil and N-desmethyl sildenafil in plasma of children.

Role of GST P1-1 in mediating the effect of etoposide on human neuroblastoma cell line Sh-Sy5y

S-Glutathionylation signaling in cell biology: Progress and prospects ⬇️

Selective adsorption of homocysteine using an HFR-ON LINE technique

Semiautomated method for determination of cystine concentration in polymorphonuclear leukocytes

Serum homocysteine, MTHFR gene polymorphism, and carotid intimal-medial thickness in NIDDM subjects

Serum homocysteine, methylenetetrahydrofolate reductase gene polymorphism and cardiovascular disease in heterozygous familial hypercholesterolemia

Simultaneous determination of ubiquinol and ubiquinone in skeletal muscle of pediatric patients

Studying nonobstructive azoospermia in cystinosis: histologic examination of testes and epididymis and sperm analysis in a Ctns−/− mouse model

Susceptibility of isolated myofibrils to in vitro glutathionylation: Potential relevance to muscle functions

Systemic Redox Biomarkers in Neurodegenerative Diseases