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List of works by Nicola J. Brown

A novel magnetic approach to enhance the efficacy of cell-based gene therapies

scientific article

A peptide derived from TIMP-3 inhibits multiple angiogenic growth factor receptors and tumour growth and inflammatory arthritis in mice

scientific article published on 16 October 2013

Alphastatin, a 24-amino acid fragment of human fibrinogen, is a potent new inhibitor of activated endothelial cells in vitro and in vivo

scientific article

Analysis of circulating angiogenic biomarkers from patients in two phase III trials in lung cancer of chemotherapy alone or chemotherapy and thalidomide ⬇️

scientific article published on February 21, 2012

Angiogenesis in pre-malignant conditions

scientific article published on 21 October 2008

Angiogenesis induction and regression in human surgical wounds

scientific article

Angiogenesis is associated with the onset of hyperplasia in human ductal breast disease.

scientific article published on 21 July 2009

Angiogenesis, vascular endothelial growth factor and its receptors in human surgical wounds

scientific article published in December 2009

Angiogenic growth factor expression in benign and malignant vascular tumours

scientific article published on 28 June 2014

Angiopoietin-1 regulates microvascular reactivity and protects the microcirculation during acute endothelial dysfunction: role of eNOS and VE-cadherin

scientific article published on 07 January 2014

Angiopoietin-1 variant reduces LPS-induced microvascular dysfunction in a murine model of sepsis

scientific article published on 04 October 2012

Angiopoietin-1, angiopoietin-2 and Tie-2 receptor expression in human dermal wound repair and scarring.

scientific article published in November 2010

Angiopoietins 1 and 2 and Tie-2 receptor expression in human ductal breast disease.

scientific article

Angiosarcoma

scientific article published on 25 May 2010

Anti-tissue factor short hairpin RNA inhibits breast cancer growth in vivo

scientific article published on 10 September 2010

Approaches to improve angiogenesis in tissue-engineered skin

scientific article

Atomic force microscopy reveals the mechanical properties of breast cancer bone metastases

scientific article published on 11 November 2021

Atorvastatin reduces endotoxin-induced microvascular inflammation via NOSII.

scientific article published on 14 February 2015

BMP-6 over-expression in prostate cancer is associated with increased Id-1 protein and a more invasive phenotype

scientific article published on February 2008

Beneficial microvascular and anti-inflammatory effects of pravastatin during sepsis involve nitric oxide synthase III.

scientific article published in February 2010

Blood vessel characterization in human dermal wound repair and scarring

scientific article published on 01 July 2011

Breast cancer cells stimulate osteoprotegerin (OPG) production by endothelial cells through direct cell contact

scientific article published on 15 July 2009

Candidate gene polymorphisms in solid cancers.

scientific article published in August 2004

Comparison of three in vitro human 'angiogenesis' assays with capillaries formed in vivo

scientific article published on 01 January 2001

Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer

scientific article published on October 2013

Current methods for assaying angiogenesis in vitro and in vivo.

scientific article published in October 2004

Current status and future prospects for anti-angiogenic therapies in cancer.

scientific article published on September 2009

Development of a reconstructed human skin model for angiogenesis

scientific article published on 01 July 2003

Differential cell death response to photodynamic therapy is dependent on dose and cell type.

scientific article published on May 2001

Differential effects of intravenous anaesthetic agents on the response of rat mesenteric microcirculation in vivo after haemorrhage

scientific article published in February 2002

Differential effects of propofol, ketamine, and thiopental anaesthesia on the skeletal muscle microcirculation of normotensive and hypertensive rats in vivo.

scientific article

Effects of Helicobacter pylori on endothelial cell proliferation and chemotaxis.

scientific article published on 16 June 2004

Effects of chronic administration of Helicobacter pylori extracts on rat gastric mucosal microcirculation in vivo

scientific article published in July 2000

Effects of genotypically different strains of Helicobacter pylori on human microvascular endothelial cells in vitro.

scientific article published in January 2001

Effects of hypothermia and rewarming on the mucosal villus microcirculation and survival after rat intestinal ischemia-reperfusion injury.

scientific article

Effects of intestinal ischemia-reperfusion injury on rat peripheral blood neutrophil activation

scientific article published on 01 September 2003

Endoscopic ablation of Barrett's oesophagus: a randomized-controlled trial of photodynamic therapy vs. argon plasma coagulation.

scientific article published in December 2004

Endostatin gene variation and protein levels in breast cancer susceptibility and severity

scientific article

Eradication of dysplastic Barrett's oesophagus using photodynamic therapy: long-term follow-up.

scientific article

Evaluation of fluorescent plasma markers for in vivo microscopy of the microcirculation

scientific article published on 18 January 2012

Expression of class 3 semaphorins and their receptors in human breast neoplasia

scientific article published on 01 August 2011

Expression of proteinases and inhibitors in human breast cancer progression and survival.

scientific article

FK409 inhibits both local and remote organ damage after intestinal ischaemia.

scientific article published in August 2002

Hypoglycaemia, chronic kidney disease and death in type 2 diabetes: the Hong Kong diabetes registry

scientific article

Identification of key residues involved in mediating the in vivo anti-tumor/anti-endothelial activity of Alphastatin

scientific article published on April 2007

Influence of VEGF-A gene variation and protein levels in breast cancer susceptibility and severity

scientific article published in September 2007

Influence of washing and quenching in profiling the metabolome of adherent mammalian cells: a case study with the metastatic breast cancer cell line MDA-MB-231.

scientific article

Interleukin gene polymorphisms and breast cancer: a case control study and systematic literature review.

scientific article published on 14 July 2006

Internalization and biodistribution of polymersomes into oral squamous cell carcinoma cells in vitro and in vivo

scientific article published on September 2010

Intravenous anesthesia inhibits leukocyte-endothelial interactions and expression of CD11b after hemorrhage

scientific article published in May 2006

L-Arginine protects and exacerbates ethanol-induced rat gastric mucosal injury.

scientific article published in August 2000

LPS abolishes extrasplenic vasoconstriction to atrial natriuretic peptide: the role of NO and endothelin 1.

scientific article published in June 2008

Lactate dehydrogenase-B is silenced by promoter methylation in a high frequency of human breast cancers

scientific article

Lipopolysaccharide alters vasodilation to atrial natriuretic peptide via nitric oxide and endothelin-1: time-dependent effects

scientific article published on 6 September 2009

Macromolecular leak from extrasplenic lymphatics during endotoxemia

scientific article published in January 2009

Macrophages promote angiogenesis in human breast tumour spheroids in vivo.

scientific article published on January 2006

Mast cell stabilization prevents ethanol-induced rat gastric mucosal injury: mechanisms of protection

scientific article published in February 2000

Matrix metalloproteinase activity and immunohistochemical profile of matrix metalloproteinase-2 and -9 and tissue inhibitor of metalloproteinase-1 during human dermal wound healing

scientific article published in May 2004

Mechanisms of Helicobacter pylori-induced rat gastric mucosal microcirculatory disturbances in vivo

scientific article published in April 2000

Microvessel density does not predict outcome in high grade soft tissue sarcoma

scientific article published on 29 June 2005

Mucosal villus microcirculatory disturbances associated with rat intestinal ischaemia-reperfusion injury are not prevented by tacrolimus.

scientific article

Near infrared fluorescence imaging of rabbit thyroid and parathyroid glands.

scientific article

Neuropilin-1 and neuropilin-2 expression in the adenoma-carcinoma sequence of colorectal cancer

scientific article published on 28 March 2013

Osteoprotegerin (OPG)-a potential new role in the regulation of endothelialcell phenotype and tumour angiogenesis?

scientific article published on 01 April 2006

Parathyroid Hormone (PTH) Increases Skeletal Tumour Growth and Alters Tumour Distribution in an In Vivo Model of Breast Cancer

scientific article published on 26 September 2018

Photodynamic therapy for dysplastic Barrett's oesophagus: a prospective, double blind, randomised, placebo controlled trial

scientific article

Prostate cancer cells home to bone using a novel in vivo model: modulation by the integrin antagonist GLPG0187.

scientific article published on 4 September 2014

Proteolysis in human breast and colorectal cancer

scientific article published on September 1999

Quantum dot-conjugated anti-GRP78 scFv inhibits cancer growth in mice

scientific article published on 16 January 2012

ROCK induced inflammation of the microcirculation during endotoxemia mediated by nitric oxide synthase

scientific article published on 23 February 2011

Rapid modification of the bone microenvironment following short-term treatment with Cabozantinib in vivo.

scientific article published on 13 August 2015

Reduced vascular response to phenylephrine during exposure to lipopolysaccharide in vitro involves nitric oxide and endothelin 1.

scientific article published in March 2008

Role of L-type calcium channels in altered microvascular responses to propofol in hypertension

scientific article

Role of genetic polymorphisms in tumour angiogenesis

scientific article

Role of tumour necrosis factor gene polymorphisms (-308 and -238) in breast cancer susceptibility and severity

scientific article

Selective measurement and manipulation of adhesion forces between cancer cells and bone marrow endothelial cells using atomic force microscopy.

scientific article published on 2 December 2012

Sorsby's fundus dystrophy mutations impair turnover of TIMP-3 by retinal pigment epithelial cells

scientific article

The dose-dependent effects of fentanyl on rat skeletal muscle microcirculation in vivo.

scientific article published in February 2003

The effect of an opiate receptor antagonist on the ileal brake mechanism in the rat

scientific article published on 01 October 1993

The effect of liquid fibre on gastric emptying in the rat and humans and the distribution of small intestinal contents in the rat

scientific article published on September 1993

The effect of photodynamic therapy (PDT) on oesophageal motility and acid clearance in patients with Barrett's oesophagus

scientific article published on 24 May 2006

The effects of pectin and wheat bran on the distribution of a meal in the gastrointestinal tract of the rat

scientific article published on 01 August 1994

The history of photodetection and photodynamic therapy.

scientific article

The nociceptin/orphanin FQ receptor antagonist UFP-101 reduces microvascular inflammation to lipopolysaccharide in vivo

scientific article

The relationship between semaphorin 3C and microvessel density in the progression of breast and oral neoplasia

scientific article published on 21 April 2015

The role of fibrinogen and related fragments in tumour angiogenesis and metastasis ⬇️

scientific article published on October 1, 2003

The role of nitric oxide in the treatment of tumours with aminolaevulinic acid-induced photodynamic therapy

scientific article published on 17 July 2010

The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies

scientific article (publication date: March 2002)

The use of 5-aminolaevulinic acid as a photosensitiser in photodynamic therapy and photodiagnosis

scientific article

Tissue factor, angiogenesis and tumour progression

scientific article published on 17 March 2008

Toxigenic Helicobacter pylori induces changes in the gastric mucosal microcirculation in rats.

scientific article published on November 2002

Trafficking of tumor peptide-specific cytotoxic T lymphocytes into the tumor microcirculation

scientific article

Use of macrophages to target therapeutic adenovirus to human prostate tumors

scientific article published on 13 January 2011

Vascular smooth muscle cell stiffness and adhesion to collagen I modified by vasoactive agonists

scientific article published on 6 March 2015

Vascular-targeted agents for the treatment of angiosarcoma

scientific article published on 20 November 2013

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