List of works - Bertrand Tavitian

1-[3-(2-[18F]fluoropyridin-3-yloxy)propyl]pyrrole-2,5-dione: design, synthesis, and radiosynthesis of a new [18F]fluoropyridine-based maleimide reagent for the labeling of peptides and proteins.

scientific article

11C-DPA-713: a novel peripheral benzodiazepine receptor PET ligand for in vivo imaging of neuroinflammation

scientific article published in April 2007

A future for PET imaging in Alzheimer's disease

scientific article published on 01 February 2020

ADSC-sheet Transplantation to Prevent Stricture after Extended Esophageal Endoscopic Submucosal Dissection.

scientific article

An autocrine loop involving ret and glial cell-derived neurotrophic factor mediates retinoic acid-induced neuroblastoma cell differentiation

scientific article published on July 2006

Analysis of the growth dynamics of angiogenesis-dependent and -independent experimental glioblastomas by multimodal small-animal PET and MRI.

scientific article published on 11 June 2012

Axonal transport reversal of acetylcholinesterase molecular forms in transected nerve

scientific article published on 01 December 1991

CRABP1 provides high malignancy of transformed mesenchymal cells and contributes to the pathogenesis of mesenchymal and neuroendocrine tumors.

scientific article

Cardiac Metabolic Deregulation Induced by the Tyrosine Kinase Receptor Inhibitor Sunitinib is rescued by Endothelin Receptor Antagonism

scientific article published on 8 July 2017

Cell Sheet Transplantation for Esophageal Stricture Prevention after Endoscopic Submucosal Dissection in a Porcine Model

scientific article

Characterization of a synthetic anionic vector for oligonucleotide delivery using in vivo whole body dynamic imaging.

scientific article published in April 2002

Co-registration of glucose metabolism with positron emission tomography and vascularity with fluorescent diffuse optical tomography in mouse tumors

scientific article

Comparative biodistribution in mice of cyanine dyes loaded in lipid nanoparticles

scientific article published on 21 March 2015

Comparative evaluation of the translocator protein radioligands 11C-DPA-713, 18F-DPA-714, and 11C-PK11195 in a rat model of acute neuroinflammation

scientific article published on 17 February 2009

Comparison of 18F-fluoro-deoxy-glucose, 18F-fluoro-methyl-choline, and 18F-DPA714 for positron-emission tomography imaging of leukocyte accumulation in the aortic wall of experimental abdominal aneurysms

scientific article published on 21 June 2012

Comparison of different strategies to select aptamers against a transmembrane protein target.

scientific article published on January 2006

Current paradigm of the 18-kDa translocator protein (TSPO) as a molecular target for PET imaging in neuroinflammation and neurodegenerative diseases.

scientific article published on 16 October 2011

Darwinian molecular imaging

scientific article published on 01 September 2009

Design and synthesis of a new [18F]fluoropyridine-based haloacetamide reagent for the labeling of oligonucleotides: 2-bromo-N-[3-(2-[18F]fluoropyridin-3-yloxy)propyl]acetamide.

scientific article

Designing 3D Mesenchymal Stem Cell Sheets Merging Magnetic and Fluorescent Features: When Cell Sheet Technology Meets Image-Guided Cell Therapy

scientific article

Developmental changes in the localization of the synaptic vesicle protein rab3A in rat brain

scientific article published in September 1994

Differential effect of functional olfactory deprivation on synaptic vesicle proteins in rat olfactory bulb

scientific article published on 01 July 1995

Differential expression of the 18 kDa translocator protein (TSPO) by neoplastic and inflammatory cells in mouse tumors of breast cancer.

scientific article published on 4 April 2011

Dissolution Dynamic Nuclear Polarization Instrumentation for Real-time Enzymatic Reaction Rate Measurements by NMR.

scientific article published on 23 February 2016

Distribution and bioactivity of the Ret-specific D4 aptamer in three-dimensional collagen gel cultures.

scientific article

Double in situ hybridization reveals overlapping neuronal populations expressing the low molecular weight GTPases Rab3a and Rab3b in Rat brain

scientific article published in April 1995

Evaluation of Antitumor Activity of Long-Circulating and pH-Sensitive Liposomes Containing Ursolic Acid in Animal Models of Breast Tumor and Gliosarcoma

scientific article

Evaluation of drug penetration into the brain: a double study by in vivo imaging with positron emission tomography and using an in vitro model of the human blood-brain barrier.

scientific article

Evaluation of the PBR/TSPO radioligand [(18)F]DPA-714 in a rat model of focal cerebral ischemia

scientific article published on 30 September 2009

Expression of the small GTP-binding protein Rab3A in the adult rat brain

scientific article published in December 1992

Fluorine-18-labeled phospholipid quantum dot micelles for in vivo multimodal imaging from whole body to cellular scales.

scientific article published on 28 August 2008

Fusion of [18F]FDG PET with Fluorescence Diffuse Optical Tomography to Improve Validation of Probes and Tumor Imaging ⬇️

scientific article published on June 1, 2013

General method to label antisense oligonucleotides with radioactive halogens for pharmacological and imaging studies

scientific article published on 01 September 2000

Genetic deficiency of indoleamine 2,3-dioxygenase promotes gut microbiota-mediated metabolic health

article

Genotype specific age related changes in a transgenic rat model of Huntington's disease

scientific article

Imaging Reactive Oxygen Species-Induced Modifications in Living Systems.

scientific article

Imaging microglial/macrophage activation in spinal cords of experimental autoimmune encephalomyelitis rats by positron emission tomography using the mitochondrial 18 kDa translocator protein radioligand [¹⁸F]DPA-714.

scientific article published in April 2012

Imaging of perfusion, angiogenesis, and tissue elasticity after stroke

scientific article

Improved synthesis of the peripheral benzodiazepine receptor ligand [11C]DPA-713 using [11C]methyl triflate.

scientific article published on 20 January 2006

In Vivo Detection of Succinate by Magnetic Resonance Spectroscopy as a Hallmark of SDHx Mutations in Paraganglioma

scientific article published on 21 October 2015

In vivo PET study of cerebral [11C] methyl- tetrahydroaminoacridine distribution and kinetics in healthy human subjects.

scientific article published in May 1999

In vivo biodistribution and pharmacokinetics of 18F-labelled Spiegelmers: a new class of oligonucleotidic radiopharmaceuticals

scientific article

In vivo brain elasticity mapping in small animals using ultrasound and its application to cerebral ischemia

In vivo cellular imaging pinpoints the role of reactive oxygen species in the early steps of adult hematopoietic reconstitution

article

In vivo evidence that the increase in matrix metalloproteinase activity occurs early after cerebral ischemia.

scientific article published in February 2012

In vivo imaging and characterization of [(18)F]DPA-714, a potential new TSPO ligand, in mouse brain and peripheral tissues using small-animal PET.

scientific article published on 6 December 2014

In vivo imaging of brain lesions with [(11)C]CLINME, a new PET radioligand of peripheral benzodiazepine receptors.

scientific article published in November 2007

In vivo imaging of neuroinflammation in the rodent brain with [11C]SSR180575, a novel indoleacetamide radioligand of the translocator protein (18 kDa).

scientific article published on 9 October 2010

In vivo imaging of neuroinflammation: a comparative study between [(18)F]PBR111, [ (11)C]CLINME and [ (11)C]PK11195 in an acute rodent model

scientific article published on 13 January 2010

In vivo imaging of oligonucleotides with positron emission tomography

scientific article published in April 1998

In vivo imaging of oligonucleotidic aptamers.

scientific article published in January 2009

In vivo imaging with oligonucleotides for diagnosis and drug development ⬇️

scientific article published on June 1, 2003

In vivo study of cerebral ischemia using Shear Wave Imaging and Ultrafast Doppler

In vivo tumor targeting using a novel intestinal pathogen-based delivery approach.

scientific article published in July 2006

In vivo validation of free-space fluorescence tomography using nuclear imaging

scientific article published on 01 September 2010

Internal radiotherapy of liver cancer with rat hepatocarcinoma-intestine-pancreas gene as a liver tumor-specific promoter

scientific article

Intestinal invalidation of the glucose transporter GLUT2 delays tissue distribution of glucose and reveals an unexpected role in gut homeostasis

scientific article

Labelled oligonucleotides as radiopharmaceuticals: pitfalls, problems and perspectives.

scientific article

Loss of HIF-1α in natural killer cells inhibits tumour growth by stimulating non-productive angiogenesis

scientific article published on 17 November 2017

Metastasis-focused cell-based SELEX generates aptamers inhibiting cell migration and invasion.

scientific article published on February 2011

Modulation of the pharmacokinetic properties of PNA: preparation of galactosyl, mannosyl, fucosyl, N-acetylgalactosaminyl, and N-acetylglucosaminyl derivatives of aminoethylglycine peptide nucleic acid monomers and their incorporation into PNA oligo

scientific article published in September 2003

Molecular imaging study on in vivo distribution and pharmacokinetics of modified small interfering RNAs (siRNAs).

scientific article

Monitoring therapeutic efficacy of sunitinib using [(18)F]FDG and [(18)F]FMISO PET in an immunocompetent model of luminal B (HER2-positive)-type mammary carcinoma

scientific article published on 22 July 2015

Multimodal In Vivo Imaging of Tumorigenesis and Response to Chemotherapy in a Transgenic Mouse Model of Mammary Cancer

scientific article

Multimodal imaging reveals temporal and spatial microglia and matrix metalloproteinase activity after experimental stroke

scientific article

New device for real-time bioluminescence imaging in moving rodents

scientific article published in September 2008

Non-invasive in vivo imaging of calcium signaling in mice

scientific article

Nuclear imaging of neuroinflammation: a comprehensive review of [11C]PK11195 challengers.

scientific article published on October 2008

Optical Tools

PET imaging of medullary thyroid carcinoma in MEN2A transgenic mice using 6-[(18)F]F-L-DOPA.

scientific article published in January 2010

Performance evaluation of the PET component of a hybrid PET/CT-ultrafast ultrasound imaging instrument

scientific article published on 21 September 2018

Positron emission tomography study of [11C]methyl-tetrahydroaminoacridine (methyl-tacrine) in baboon brain

scientific article published in May 1993

Proteomic analysis of beta-catenin activation in mouse liver by DIGE analysis identifies glucose metabolism as a new target of the Wnt pathway.

scientific article published in August 2009

Pyruvate cellular uptake and enzymatic conversion probed by dissolution DNP-NMR: the impact of overexpressed membrane transporters

scientific article published on 12 November 2016

Quantitative organ time activity curve extraction from rodent PET images without anatomical prior

scientific article published in April 2010

Rab3A immunolocalization in the mammalian vestibular end-organs during development and comparison with synaptophysin expression

scientific article published in March 1997

Radioisotopic imaging of neuroinflammation

scientific article

Rat brain acetylcholinesterase visualized with [11C]physostigmine

scientific article

Realizing the full potential of PET for measuring the biodistribution of novel anticancer agents

scientific article published on 8 August 2011

Reduced PBR/TSPO expression after minocycline treatment in a rat model of focal cerebral ischemia: a PET study using [(18)F]DPA-714.

scientific article published in February 2011

Retracted: Differential SELEX in Human Glioma Cell Lines

retracted article

Retraction: Neutralizing Aptamers from Whole-Cell SELEX Inhibit the RET Receptor Tyrosine Kinase

Segmentation of rodent whole-body dynamic PET images: an unsupervised method based on voxel dynamics

scientific article published in March 2008

Serum-stable RNA aptamers to urokinase-type plasminogen activator blocking receptor binding.

scientific article

Similar expression profiles of a core of genes and proteins in cells that have acquired a metastatic phenotype, genetically or by in vivo evolution

scientific article

Simultaneous positron emission tomography and ultrafast ultrasound for hybrid molecular, anatomical and functional imaging

scientific article published on 06 February 2018

Single photon emission computed tomography/positron emission tomography imaging and targeted radionuclide therapy of melanoma: new multimodal fluorinated and iodinated radiotracers

scientific article published on 21 March 2011

Slow and fast axonal transport of acetylcholinesterase molecular forms in polyarthritic rats

scientific article published in June 1986

Sodium iodide symporter is expressed at the preneoplastic stages of liver carcinogenesis and in human cholangiocarcinoma

scientific article

Spatiotemporal matrix image formation for programmable ultrasound scanners

scientific article published on 9 January 2018

Specific biomarkers of receptors, pathways of inhibition and targeted therapies: pre-clinical developments.

scientific article published on December 2011

Synthesis of 6-[¹⁸F]fluoro-PBR28, a novel radiotracer for imaging the TSPO 18 kDa with PET.

scientific article published on 17 June 2011

Synthesis of [11C]RPR-72840A and its evaluation as a radioligand for the serotonin reuptake site in positron emission tomography

scientific article published on 01 February 1997

Synthesis, radiolabeling with fluorine-18 and preliminary in vivo evaluation of a heparan sulphate mimetic as potent angiogenesis and heparanase inhibitor for cancer applications

scientific article

Synthetic lipid nanoparticles targeting steroid organs

scientific article published on 26 September 2013

The translocator protein ligand [¹⁸F]DPA-714 images glioma and activated microglia in vivo

scientific article published on 21 January 2012

The translocator protein radioligand 18F-DPA-714 monitors antitumor effect of erufosine in a rat 9L intracranial glioma model.

scientific article published on 8 November 2013

Tumor-targeted polydiacetylene micelles for in vivo imaging and drug delivery

scientific article

[Aptamers: selection and scope of applications]

scientific article published on 05 May 2006

List of works by Bertrand Tavitian

1-[3-(2-[18F]fluoropyridin-3-yloxy)propyl]pyrrole-2,5-dione: design, synthesis, and radiosynthesis of a new [18F]fluoropyridine-based maleimide reagent for the labeling of peptides and proteins.

11C-DPA-713: a novel peripheral benzodiazepine receptor PET ligand for in vivo imaging of neuroinflammation

A future for PET imaging in Alzheimer's disease

ADSC-sheet Transplantation to Prevent Stricture after Extended Esophageal Endoscopic Submucosal Dissection.

An autocrine loop involving ret and glial cell-derived neurotrophic factor mediates retinoic acid-induced neuroblastoma cell differentiation

Analysis of the growth dynamics of angiogenesis-dependent and -independent experimental glioblastomas by multimodal small-animal PET and MRI.

Axonal transport reversal of acetylcholinesterase molecular forms in transected nerve

CRABP1 provides high malignancy of transformed mesenchymal cells and contributes to the pathogenesis of mesenchymal and neuroendocrine tumors.

Cardiac Metabolic Deregulation Induced by the Tyrosine Kinase Receptor Inhibitor Sunitinib is rescued by Endothelin Receptor Antagonism

Cell Sheet Transplantation for Esophageal Stricture Prevention after Endoscopic Submucosal Dissection in a Porcine Model

Characterization of a synthetic anionic vector for oligonucleotide delivery using in vivo whole body dynamic imaging.

Co-registration of glucose metabolism with positron emission tomography and vascularity with fluorescent diffuse optical tomography in mouse tumors

Comparative biodistribution in mice of cyanine dyes loaded in lipid nanoparticles

Comparative evaluation of the translocator protein radioligands 11C-DPA-713, 18F-DPA-714, and 11C-PK11195 in a rat model of acute neuroinflammation

Comparison of 18F-fluoro-deoxy-glucose, 18F-fluoro-methyl-choline, and 18F-DPA714 for positron-emission tomography imaging of leukocyte accumulation in the aortic wall of experimental abdominal aneurysms

Comparison of different strategies to select aptamers against a transmembrane protein target.

Current paradigm of the 18-kDa translocator protein (TSPO) as a molecular target for PET imaging in neuroinflammation and neurodegenerative diseases.

Darwinian molecular imaging

Design and synthesis of a new [18F]fluoropyridine-based haloacetamide reagent for the labeling of oligonucleotides: 2-bromo-N-[3-(2-[18F]fluoropyridin-3-yloxy)propyl]acetamide.

Designing 3D Mesenchymal Stem Cell Sheets Merging Magnetic and Fluorescent Features: When Cell Sheet Technology Meets Image-Guided Cell Therapy

Developmental changes in the localization of the synaptic vesicle protein rab3A in rat brain

Differential effect of functional olfactory deprivation on synaptic vesicle proteins in rat olfactory bulb

Differential expression of the 18 kDa translocator protein (TSPO) by neoplastic and inflammatory cells in mouse tumors of breast cancer.

Dissolution Dynamic Nuclear Polarization Instrumentation for Real-time Enzymatic Reaction Rate Measurements by NMR.

Distribution and bioactivity of the Ret-specific D4 aptamer in three-dimensional collagen gel cultures.

Double in situ hybridization reveals overlapping neuronal populations expressing the low molecular weight GTPases Rab3a and Rab3b in Rat brain

Evaluation of Antitumor Activity of Long-Circulating and pH-Sensitive Liposomes Containing Ursolic Acid in Animal Models of Breast Tumor and Gliosarcoma

Evaluation of drug penetration into the brain: a double study by in vivo imaging with positron emission tomography and using an in vitro model of the human blood-brain barrier.

Evaluation of the PBR/TSPO radioligand [(18)F]DPA-714 in a rat model of focal cerebral ischemia

Expression of the small GTP-binding protein Rab3A in the adult rat brain

Fluorine-18-labeled phospholipid quantum dot micelles for in vivo multimodal imaging from whole body to cellular scales.

Fusion of [18F]FDG PET with Fluorescence Diffuse Optical Tomography to Improve Validation of Probes and Tumor Imaging ⬇️

General method to label antisense oligonucleotides with radioactive halogens for pharmacological and imaging studies

Genetic deficiency of indoleamine 2,3-dioxygenase promotes gut microbiota-mediated metabolic health

Genotype specific age related changes in a transgenic rat model of Huntington's disease

Imaging Reactive Oxygen Species-Induced Modifications in Living Systems.

Imaging microglial/macrophage activation in spinal cords of experimental autoimmune encephalomyelitis rats by positron emission tomography using the mitochondrial 18 kDa translocator protein radioligand [¹⁸F]DPA-714.

Imaging of perfusion, angiogenesis, and tissue elasticity after stroke

Improved synthesis of the peripheral benzodiazepine receptor ligand [11C]DPA-713 using [11C]methyl triflate.

In Vivo Detection of Succinate by Magnetic Resonance Spectroscopy as a Hallmark of SDHx Mutations in Paraganglioma

In vivo PET study of cerebral [11C] methyl- tetrahydroaminoacridine distribution and kinetics in healthy human subjects.

In vivo biodistribution and pharmacokinetics of 18F-labelled Spiegelmers: a new class of oligonucleotidic radiopharmaceuticals

In vivo brain elasticity mapping in small animals using ultrasound and its application to cerebral ischemia

In vivo cellular imaging pinpoints the role of reactive oxygen species in the early steps of adult hematopoietic reconstitution

In vivo evidence that the increase in matrix metalloproteinase activity occurs early after cerebral ischemia.

In vivo imaging and characterization of [(18)F]DPA-714, a potential new TSPO ligand, in mouse brain and peripheral tissues using small-animal PET.

In vivo imaging of brain lesions with [(11)C]CLINME, a new PET radioligand of peripheral benzodiazepine receptors.

In vivo imaging of neuroinflammation in the rodent brain with [11C]SSR180575, a novel indoleacetamide radioligand of the translocator protein (18 kDa).

In vivo imaging of neuroinflammation: a comparative study between [(18)F]PBR111, [ (11)C]CLINME and [ (11)C]PK11195 in an acute rodent model

In vivo imaging of oligonucleotides with positron emission tomography

In vivo imaging of oligonucleotidic aptamers.

In vivo imaging with oligonucleotides for diagnosis and drug development ⬇️

In vivo study of cerebral ischemia using Shear Wave Imaging and Ultrafast Doppler

In vivo tumor targeting using a novel intestinal pathogen-based delivery approach.

In vivo validation of free-space fluorescence tomography using nuclear imaging

Internal radiotherapy of liver cancer with rat hepatocarcinoma-intestine-pancreas gene as a liver tumor-specific promoter

Intestinal invalidation of the glucose transporter GLUT2 delays tissue distribution of glucose and reveals an unexpected role in gut homeostasis

Labelled oligonucleotides as radiopharmaceuticals: pitfalls, problems and perspectives.

Loss of HIF-1α in natural killer cells inhibits tumour growth by stimulating non-productive angiogenesis

Metastasis-focused cell-based SELEX generates aptamers inhibiting cell migration and invasion.

Modulation of the pharmacokinetic properties of PNA: preparation of galactosyl, mannosyl, fucosyl, N-acetylgalactosaminyl, and N-acetylglucosaminyl derivatives of aminoethylglycine peptide nucleic acid monomers and their incorporation into PNA oligo

Molecular imaging study on in vivo distribution and pharmacokinetics of modified small interfering RNAs (siRNAs).

Monitoring therapeutic efficacy of sunitinib using [(18)F]FDG and [(18)F]FMISO PET in an immunocompetent model of luminal B (HER2-positive)-type mammary carcinoma

Multimodal In Vivo Imaging of Tumorigenesis and Response to Chemotherapy in a Transgenic Mouse Model of Mammary Cancer

Multimodal imaging reveals temporal and spatial microglia and matrix metalloproteinase activity after experimental stroke

New device for real-time bioluminescence imaging in moving rodents

Non-invasive in vivo imaging of calcium signaling in mice

Nuclear imaging of neuroinflammation: a comprehensive review of [11C]PK11195 challengers.

Optical Tools

PET imaging of medullary thyroid carcinoma in MEN2A transgenic mice using 6-[(18)F]F-L-DOPA.

Performance evaluation of the PET component of a hybrid PET/CT-ultrafast ultrasound imaging instrument

Positron emission tomography study of [11C]methyl-tetrahydroaminoacridine (methyl-tacrine) in baboon brain

Proteomic analysis of beta-catenin activation in mouse liver by DIGE analysis identifies glucose metabolism as a new target of the Wnt pathway.

Pyruvate cellular uptake and enzymatic conversion probed by dissolution DNP-NMR: the impact of overexpressed membrane transporters

Quantitative organ time activity curve extraction from rodent PET images without anatomical prior

Rab3A immunolocalization in the mammalian vestibular end-organs during development and comparison with synaptophysin expression

Radioisotopic imaging of neuroinflammation

Rat brain acetylcholinesterase visualized with [11C]physostigmine

Realizing the full potential of PET for measuring the biodistribution of novel anticancer agents