List of works - Ann M Stock

A common dimerization interface in bacterial response regulators KdpE and TorR.

scientific article

A new perspective on response regulator activation

scientific article published on November 2006

Activation of methylesterase CheB: evidence of a dual role for the regulatory domain

scientific article

Bacterial chemotaxis: a field in motion

scientific article

Bacterial response regulators: versatile regulatory strategies from common domains

scientific article published on 12 April 2007

Biological insights from structures of two-component proteins

scientific article published on January 2009

Bright lights, abundant operons--fluorescence and genomic technologies advance studies of bacterial locomotion and signal transduction: review of the BLAST meeting, Cuernavaca, Mexico, 14 to 19 January 2001.

scientific article published on January 2002

Catalytically incompetent by design

scientific article published on August 2009

Characterization of the Thermotoga maritima chemotaxis methylation system that lacks pentapeptide-dependent methyltransferase CheR:MCP tethering

scientific article published on 5 December 2006

Characterization of the genes and proteins of a two-component system from the hyperthermophilic bacterium Thermotoga maritima

scientific article

Chemotaxis receptor recognition by protein methyltransferase CheR

scientific article

Classic Spotlights: Selected Highlights from the First 100 Years of the Journal of Bacteriology

scientific article published on 13 June 2017

Comprehensive analysis of OmpR phosphorylation, dimerization, and DNA binding supports a canonical model for activation

scientific article

Counterbalancing Regulation in Response Memory of a Positively Autoregulated Two-Component System

scientific article

Crystal Structure and Autoactivation Pathway of the Precursor Form of Human Tripeptidyl-peptidase 1, the Enzyme Deficient in Late Infantile Ceroid Lipofuscinosis

scientific article

Crystal Structures of the Receiver Domain of the Response Regulator PhoP from Escherichia coli in the Absence and Presence of the Phosphoryl Analog Beryllofluoride

scientific article

Crystal structure of the chemotaxis receptor methyltransferase CheR suggests a conserved structural motif for binding S-adenosylmethionine

scientific article

Crystal structures of beryllium fluoride-free and beryllium fluoride-bound CheY in complex with the conserved C-terminal peptide of CheZ reveal dual binding modes specific to CheY conformation

scientific article published on 6 April 2006

Crystallization, X-ray studies, and site-directed cysteine mutagenesis of the DNA-binding domain of OmpR.

scientific article published on July 1996

Cytokinin Sensing in Bacteria

scientific article published on 25 January 2020

Diguanylate cyclase activation: it takes two.

scientific article published in August 2007

Discrimination between different methylation states of chemotaxis receptor Tar by receptor methyltransferase CheR.

scientific article published on February 2004

Do mammalian NPC1 and NPC2 play a role in intestinal cholesterol absorption?

scientific article

Domain Orientation in the Inactive Response Regulator Mycobacterium tuberculosis MtrA Provides a Barrier to Activation † , ‡

scientific article

Domain arrangement of Der, a switch protein containing two GTPase domains

scientific article

Drug-like Fragments Inhibit agr-Mediated Virulence Expression in Staphylococcus aureus

scientific article published on 01 May 2019

Energy sensors for aerotaxis in Escherichia coli: something old, something new.

scientific article

Evidence of intradomain and interdomain flexibility in an OmpR/PhoB homolog from Thermotoga maritima

scientific article

Evolutionary tuning of protein expression levels of a positively autoregulated two-component system

scientific article

Identification of a Hydrophobic Cleft in the LytTR Domain of AgrA as a Locus for Small Molecule Interactions That Inhibit DNA Binding

scientific article

Identification of methylation sites in Thermotoga maritima chemotaxis receptors

scientific article

Inhibition of bacterial virulence: drug-like molecules targeting the Salmonella enterica PhoP response regulator

scientific article

Interaction of CheY with the C-Terminal Peptide of CheZ

scientific article

Kinetic basis for the stimulatory effect of phosphorylation on the methylesterase activity of CheB.

scientific article published on May 2002

Loss of Niemann-Pick C1 or C2 protein results in similar biochemical changes suggesting that these proteins function in a common lysosomal pathway

scientific article

Mechanism of activation for transcription factor PhoB suggested by different modes of dimerization in the inactive and active states

scientific article published on September 2005

Molecular information processing: lessons from bacterial chemotaxis

scientific article

Molecular strategies for phosphorylation-mediated regulation of response regulator activity

scientific article published on 14 January 2010

NPC2, the protein deficient in Niemann-Pick C2 disease, consists of multiple glycoforms that bind a variety of sterols

scientific article

Orientation of OmpR monomers within an OmpR:DNA complex determined by DNA affinity cleaving 1 1Edited by K. Yamamoto

scientific article published on 01 January 1999

Phosphorylation-dependent conformational changes and domain rearrangements in Staphylococcus aureus VraR activation

scientific article

Probing kinase and phosphatase activities of two-component systems in vivo with concentration-dependent phosphorylation profiling

scientific article published on 24 December 2012

Probing the roles of the two different dimers mediated by the receiver domain of the response regulator PhoB.

scientific article published on 14 April 2009

Purification, crystallization, and preliminary X-ray diffraction analyses of the bacterial chemotaxis receptor modifying enzymes.

scientific article published in April 1995

Quantitative Kinetic Analyses of Shutting Off a Two-Component System

scientific article

Regulation of Response Regulator Autophosphorylation through Interdomain Contacts

scientific article

Stabilization of the phospho-aspartyl residue in a two-component signal transduction system in Thermotoga maritima

scientific article published in October 1998

Structural Analysis of the Domain Interface in DrrB, a Response Regulator of the OmpR/PhoB Subfamily

scientific article

Structural Basis of Sterol Binding by NPC2, a Lysosomal Protein Deficient in Niemann-Pick Type C2 Disease

scientific article

Structural analysis and solution studies of the activated regulatory domain of the response regulator ArcA: a symmetric dimer mediated by the alpha4-beta5-alpha5 face

scientific article published on 07 April 2005

Structural analysis of bacterial chemotaxis proteins: components of a dynamic signaling system.

scientific article

Structural asymmetry does not indicate hemi-phosphorylation in the bacterial histidine kinase CpxA

scientific article published on 24 February 2020

Structural basis for methylesterase CheB regulation by a phosphorylation-activated domain

scientific article

Structural relationships in the OmpR family of winged-helix transcription factors

scientific article published on June 1997

Structure of a cholesterol-binding protein deficient in Niemann-Pick type C2 disease

scientific article

Structure of the Staphylococcus aureus AgrA LytTR Domain Bound to DNA Reveals a Beta Fold with an Unusual Mode of Binding

scientific article

Synthesis and biochemical characterization of a phosphorylated analogue of the response regulator CheB.

scientific article published in October 2001

Synthesis of [(32)P]phosphoramidate for use as a low molecular weight phosphodonor reagent

scientific article published in August 2000

System-level mapping of Escherichia coli response regulator dimerization with FRET hybrids

scientific article published on 09 July 2008

The DNA-binding domain of OmpR: crystal structures of a winged helix transcription factor

scientific article

The PLOS Biology XV Collection: 15 Years of Exceptional Science Highlighted across 12 Months

scientific article published on 27 February 2019

Thiol-based functional mimicry of phosphorylation of the two-component system response regulator ArcA promotes pathogenesis in enteric pathogens

scientific article published on 01 December 2021

Transmembrane signaling by asymmetry

scientific article published on 01 October 2006

Two-Component Signal Transduction: a Special Issue in the Journal of Bacteriology

scientific article

Universally applicable methods for monitoring response regulator aspartate phosphorylation both in vitro and in vivo using Phos-tag-based reagents

scientific article published on 13 February 2008

What do archaeal and eukaryotic histidine kinases sense?

scientific article published on 27 December 2019

List of works by Ann M Stock

A common dimerization interface in bacterial response regulators KdpE and TorR.

A new perspective on response regulator activation

Activation of methylesterase CheB: evidence of a dual role for the regulatory domain

Bacterial chemotaxis: a field in motion

Bacterial response regulators: versatile regulatory strategies from common domains

Biological insights from structures of two-component proteins

Bright lights, abundant operons--fluorescence and genomic technologies advance studies of bacterial locomotion and signal transduction: review of the BLAST meeting, Cuernavaca, Mexico, 14 to 19 January 2001.

Catalytically incompetent by design

Characterization of the Thermotoga maritima chemotaxis methylation system that lacks pentapeptide-dependent methyltransferase CheR:MCP tethering

Characterization of the genes and proteins of a two-component system from the hyperthermophilic bacterium Thermotoga maritima

Chemotaxis receptor recognition by protein methyltransferase CheR

Classic Spotlights: Selected Highlights from the First 100 Years of the Journal of Bacteriology

Comprehensive analysis of OmpR phosphorylation, dimerization, and DNA binding supports a canonical model for activation

Counterbalancing Regulation in Response Memory of a Positively Autoregulated Two-Component System

Crystal Structure and Autoactivation Pathway of the Precursor Form of Human Tripeptidyl-peptidase 1, the Enzyme Deficient in Late Infantile Ceroid Lipofuscinosis

Crystal Structures of the Receiver Domain of the Response Regulator PhoP from Escherichia coli in the Absence and Presence of the Phosphoryl Analog Beryllofluoride

Crystal structure of the chemotaxis receptor methyltransferase CheR suggests a conserved structural motif for binding S-adenosylmethionine

Crystal structures of beryllium fluoride-free and beryllium fluoride-bound CheY in complex with the conserved C-terminal peptide of CheZ reveal dual binding modes specific to CheY conformation

Crystallization, X-ray studies, and site-directed cysteine mutagenesis of the DNA-binding domain of OmpR.

Cytokinin Sensing in Bacteria

Diguanylate cyclase activation: it takes two.

Discrimination between different methylation states of chemotaxis receptor Tar by receptor methyltransferase CheR.

Do mammalian NPC1 and NPC2 play a role in intestinal cholesterol absorption?

Domain Orientation in the Inactive Response Regulator Mycobacterium tuberculosis MtrA Provides a Barrier to Activation † , ‡

Domain arrangement of Der, a switch protein containing two GTPase domains

Drug-like Fragments Inhibit agr-Mediated Virulence Expression in Staphylococcus aureus

Energy sensors for aerotaxis in Escherichia coli: something old, something new.

Evidence of intradomain and interdomain flexibility in an OmpR/PhoB homolog from Thermotoga maritima

Evolutionary tuning of protein expression levels of a positively autoregulated two-component system

Identification of a Hydrophobic Cleft in the LytTR Domain of AgrA as a Locus for Small Molecule Interactions That Inhibit DNA Binding

Identification of methylation sites in Thermotoga maritima chemotaxis receptors

Inhibition of bacterial virulence: drug-like molecules targeting the Salmonella enterica PhoP response regulator

Interaction of CheY with the C-Terminal Peptide of CheZ

Kinetic basis for the stimulatory effect of phosphorylation on the methylesterase activity of CheB.

Loss of Niemann-Pick C1 or C2 protein results in similar biochemical changes suggesting that these proteins function in a common lysosomal pathway

Mechanism of activation for transcription factor PhoB suggested by different modes of dimerization in the inactive and active states

Molecular information processing: lessons from bacterial chemotaxis

Molecular strategies for phosphorylation-mediated regulation of response regulator activity

NPC2, the protein deficient in Niemann-Pick C2 disease, consists of multiple glycoforms that bind a variety of sterols

Orientation of OmpR monomers within an OmpR:DNA complex determined by DNA affinity cleaving 1 1Edited by K. Yamamoto

Phosphorylation-dependent conformational changes and domain rearrangements in Staphylococcus aureus VraR activation

Probing kinase and phosphatase activities of two-component systems in vivo with concentration-dependent phosphorylation profiling

Probing the roles of the two different dimers mediated by the receiver domain of the response regulator PhoB.

Purification, crystallization, and preliminary X-ray diffraction analyses of the bacterial chemotaxis receptor modifying enzymes.

Quantitative Kinetic Analyses of Shutting Off a Two-Component System

Regulation of Response Regulator Autophosphorylation through Interdomain Contacts

Stabilization of the phospho-aspartyl residue in a two-component signal transduction system in Thermotoga maritima

Structural Analysis of the Domain Interface in DrrB, a Response Regulator of the OmpR/PhoB Subfamily

Structural Basis of Sterol Binding by NPC2, a Lysosomal Protein Deficient in Niemann-Pick Type C2 Disease

Structural analysis and solution studies of the activated regulatory domain of the response regulator ArcA: a symmetric dimer mediated by the alpha4-beta5-alpha5 face

Structural analysis of bacterial chemotaxis proteins: components of a dynamic signaling system.

Structural asymmetry does not indicate hemi-phosphorylation in the bacterial histidine kinase CpxA

Structural basis for methylesterase CheB regulation by a phosphorylation-activated domain

Structural relationships in the OmpR family of winged-helix transcription factors

Structure of a cholesterol-binding protein deficient in Niemann-Pick type C2 disease

Structure of the Staphylococcus aureus AgrA LytTR Domain Bound to DNA Reveals a Beta Fold with an Unusual Mode of Binding

Synthesis and biochemical characterization of a phosphorylated analogue of the response regulator CheB.

Synthesis of [(32)P]phosphoramidate for use as a low molecular weight phosphodonor reagent

System-level mapping of Escherichia coli response regulator dimerization with FRET hybrids

The DNA-binding domain of OmpR: crystal structures of a winged helix transcription factor

The PLOS Biology XV Collection: 15 Years of Exceptional Science Highlighted across 12 Months

Thiol-based functional mimicry of phosphorylation of the two-component system response regulator ArcA promotes pathogenesis in enteric pathogens

Transmembrane signaling by asymmetry

Two-Component Signal Transduction: a Special Issue in the Journal of Bacteriology

Universally applicable methods for monitoring response regulator aspartate phosphorylation both in vitro and in vivo using Phos-tag-based reagents

What do archaeal and eukaryotic histidine kinases sense?