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List of works by Helen M. Arthur

A direct interaction between TGFbeta activated kinase 1 and the TGFbeta type II receptor: implications for TGFbeta signalling and cardiac hypertrophy

scientific journal article

Angiogenesis regulation by TGFβ signalling: clues from an inherited vascular disease

scientific article published on December 2011

Angiotensin II-induced cardiomyocyte hypertrophy in vitro is TAK1-dependent and Smad2/3-independent.

scientific article

Arterial endoglin does not protect against arteriovenous malformations

scientific article published on 06 June 2020

Cardiosphere-Derived Cells Require Endoglin for Paracrine-Mediated Angiogenesis

scientific article published on May 2017

Circulating Endothelial Progenitor Cells Exhibit Diurnal Variation

scientific article published on 01 March 2008

Circulating endothelial progenitor cell numbers are not associated with donor organ age or allograft vasculopathy in cardiac transplant recipients

scientific article published on 20 May 2008

Clearance of senescent cells during cardiac ischemia-reperfusion injury improves recovery

scientific article published on 29 September 2020

Cloning of the uvrD gene of E. coli and identification of the product

article

Common and distinctive pathogenetic features of arteriovenous malformations in hereditary hemorrhagic telangiectasia 1 and hereditary hemorrhagic telangiectasia 2 animal models--brief report.

scientific article published on 31 July 2014

Defective paracrine signalling by TGFbeta in yolk sac vasculature of endoglin mutant mice: a paradigm for hereditary haemorrhagic telangiectasia

scientific article

Deficiency for endoglin in tumor vasculature weakens the endothelial barrier to metastatic dissemination

scientific article published on 11 February 2013

ENDOGLIN is dispensable for vasculogenesis, but required for vascular endothelial growth factor-induced angiogenesis

scientific article published on 28 January 2014

Endoglin and activin receptor-like-kinase 1 are co-expressed in the distal vessels of the lung: implications for two familial vascular dysplasias, HHT and PAH.

scientific article

Endoglin expression in early development is associated with vasculogenesis and angiogenesis

scientific article published on January 1, 2002

Endoglin has a crucial role in blood cell-mediated vascular repair

scientific article published on 6 November 2006

Endoglin is required in Pax3-derived cells for embryonic blood vessel formation.

scientific article published on 16 October 2015

Endoglin prevents vascular malformation by regulating flow-induced cell migration and specification through VEGFR2 signalling

scientific article published on 22 May 2017

Endoglin promotes endothelial cell proliferation and TGF-beta/ALK1 signal transduction

scientific article published on 23 September 2004

Endothelial depletion of Acvrl1 in mice leads to arteriovenous malformations associated with reduced endoglin expression

scientific article

Endothelial expression of TGFβ type II receptor is required to maintain vascular integrity during postnatal development of the central nervous system

scientific article (publication date: 2012)

Executive summary of the 11th HHT international scientific conference

scientific article published on 21 September 2015

Executive summary of the 12th HHT international scientific conference.

scientific article published on 16 November 2017

Extracellular control of TGFbeta signalling in vascular development and disease

scientific article published on November 2007

Generation of a floxed allele of the mouse Endoglin gene

scientific article

Hyper-recombination in uvrD mutants of Escherichia coli K-12

article

Inhibiting DPP4 in a mouse model of HHT1 results in a shift towards regenerative macrophages and reduces fibrosis after myocardial infarction

scientific article published on 18 December 2017

Interaction Between ALK1 Signaling and Connexin40 in the Development of Arteriovenous Malformations.

scientific article published on 28 January 2016

LRG1 promotes angiogenesis by modulating endothelial TGF-β signalling.

scientific article

Mice Lacking Endoglin in Macrophages Show an Impaired Immune Response

scientific article

Microinjection of Escherichia coli UvrA, B, C and D proteins into fibroblasts of xeroderma pigmentosum complementation groups A and C does not result in restoration of UV-induced unscheduled DNA synthesis.

scientific article

Microvessels of the heart: Formation, regeneration, and dysfunction.

scientific article

Minimal homozygous endothelial deletion of Eng with VEGF stimulation is sufficient to cause cerebrovascular dysplasia in the adult mouse

scientific article published on 9 May 2012

Modulation of endoglin expression in islets of langerhans by VEGF reveals a novel regulator of islet endothelial cell function

scientific article

Mouse model for hereditary hemorrhagic telangiectasia has a generalized vascular abnormality

scientific article published on 17 March 2003

Mouse models of hereditary hemorrhagic telangiectasia: recent advances and future challenges

scientific article

Nonsynonymous variants in the SMAD6 gene predispose to congenital cardiovascular malformation

scientific article published on 14 February 2012

Novel brain arteriovenous malformation mouse models for type 1 hereditary hemorrhagic telangiectasia

scientific article

Pathogenesis of Arteriovenous Malformations in the Absence of Endoglin

scientific article published on 11 March 2010

Persistent infiltration and pro-inflammatory differentiation of monocytes cause unresolved inflammation in brain arteriovenous malformation

scientific article published on 20 June 2016

Pharmacological clearance of senescent cells improves survival and recovery in aged mice following acute myocardial infarction

scientific article published on 28 March 2019

Soluble endoglin regulates expression of angiogenesis-related proteins and induction of arteriovenous malformations in a mouse model of hereditary hemorrhagic telangiectasia

TGFβ signaling and congenital heart disease: Insights from mouse studies

scientific article published on 28 April 2011

Thalidomide stimulates vessel maturation and reduces epistaxis in individuals with hereditary hemorrhagic telangiectasia

scientific article

The E. coli uvrD gene product is DNA helicase II

article

The H9C2 cell line and primary neonatal cardiomyocyte cells show similar hypertrophic responses in vitro

scientific article published on 17 November 2010

The pattern of segment formation, as revealed by engrailed expression, in a centipede with a variable number of segments

scientific article published in March 2003

The secret life of nonclassical monocytes.

scientific article published on 27 October 2017

The tissue-specific RNA binding protein T-STAR controls regional splicing patterns of neurexin pre-mRNAs in the brain

scientific article

Therapeutic Potential of Senolytics in Cardiovascular Disease

scientific article published on 26 September 2020

Therapeutic levels of aspirin and salicylate directly inhibit a model of angiogenesis through a Cox-independent mechanism

scientific article (publication date: October 2006)

Transcriptional control of the uvrD gene of Escherichia coli

article

Using MRI to predict future adverse cardiac remodelling in a male mouse model of myocardial infarction

scientific article published on 16 March 2016