List of works - Julie De Backer

2015 ESC Guidelines for the management of infective endocarditis: The Task Force for the Management of Infective Endocarditis of the European Society of Cardiology (ESC). Endorsed by: European Association for Cardio-Thoracic Surgery (EACTS), the Eur

scientific article published on 29 August 2015

2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy

A critical analysis of minor cardiovascular criteria in the diagnostic evaluation of patients with Marfan syndrome.

scientific article published in July 2006

A different view on predictors of pulmonary hypertension in secundum atrial septal defect

scientific article

A syndrome of altered cardiovascular, craniofacial, neurocognitive and skeletal development caused by mutations in TGFBR1 or TGFBR2

scientific article (publication date: March 2005)

Aggressive cardiovascular phenotype of aneurysms-osteoarthritis syndrome caused by pathogenic SMAD3 variants

scientific article published on 23 May 2012

Ambulatory Electrocardiographic Monitoring and Ectopic Beat Detection in Conscious Mice

scientific article published on 10 July 2020

Aneurysm syndromes caused by mutations in the TGF-beta receptor

scientific article

Aneurysm-osteoarthritis syndrome with visceral and iliac artery aneurysms

scientific article

Aortic disease in Marfan syndrome is caused by overactivation of sGC-PRKG signaling by NO

scientific article published on 11 May 2021

Applying massive parallel sequencing to molecular diagnosis of Marfan and Loeys-Dietz syndromes

scientific article

Arterial hypertension in Turner syndrome: a review of the literature and a practical approach for diagnosis and treatment

scientific article published on July 2015

Atenolol versus losartan in children and young adults with Marfan's syndrome

scientific article

Body mass index in adults with congenital heart disease

scientific article published on 25 January 2019

Cardiovascular Health in Turner Syndrome: A Scientific Statement From the American Heart Association

article

Cardiovascular imaging in Turner syndrome: state-of-the-art practice across the lifespan

scientific article published on 18 September 2018

Cardiovascular manifestations in men and women carrying a FBN1 mutation

scientific article published on 13 August 2010

Case-matched Comparison of Cardiovascular Outcome in Loeys-Dietz Syndrome versus Marfan Syndrome

scientific article published on 29 November 2019

Characteristics of children and young adults with Marfan syndrome and aortic root dilation in a randomized trial comparing atenolol and losartan therapy

scientific article

Characterization of cardiovascular involvement in pseudoxanthoma elasticum families

scientific article published on 22 August 2013

Circulating transforming growth factor-beta in Marfan syndrome

scientific article

Clinical Validity of Genes for Heritable Thoracic Aortic Aneurysm and Dissection

article

Clinical and molecular study of 320 children with Marfan syndrome and related type I fibrillinopathies in a series of 1009 probands with pathogenic FBN1 mutations

scientific article

Comprehensive clinical and molecular assessment of 32 probands with congenital contractural arachnodactyly: report of 14 novel mutations and review of the literature

scientific article

Comprehensive molecular analysis demonstrates type V collagen mutations in over 90% of patients with classic EDS and allows to refine diagnostic criteria

scientific article published on 5 July 2012

Design and rationale of a prospective, collaborative meta-analysis of all randomized controlled trials of angiotensin receptor antagonists in Marfan syndrome, based on individual patient data: A report from the Marfan Treatment Trialists' Collaborat

scientific article published on 12 February 2015

Diagnosis, natural history, and management in vascular Ehlers-Danlos syndrome

scientific article

Diastolic dysfunction, infarct size, and exercise capacity in remote myocardial infarction: a combined approach of mitral E-wave deceleration time and color M-mode flow propagation velocity

scientific article published in March 2002

Disproportion and dysmorphism in an adult Belgian population with Turner syndrome: risk factors for chronic diseases?

scientific article published on 26 April 2019

Echocardiographic methods, quality review, and measurement accuracy in a randomized multicenter clinical trial of Marfan syndrome

scientific article published on 10 April 2013

Echocardiographically estimated left ventricular end-diastolic and right ventricular systolic pressure in normotensive healthy individuals

scientific article published on 16 March 2006

Effect of an Abdominal Aortic Aneurysm on Wave Reflection in the Aorta

article

Effect of celiprolol on prevention of cardiovascular events in vascular Ehlers-Danlos syndrome: a prospective randomised, open, blinded-endpoints trial.

scientific article

Effects of age, gender, and left ventricular mass on septal mitral annulus velocity (E') and the ratio of transmitral early peak velocity to E' (E/E').

scientific article published in April 2005

Efficacy of losartan as add-on therapy to prevent aortic growth and ventricular dysfunction in patients with Marfan syndrome: a randomized, double-blind clinical trial

scientific article published on 28 June 2017

Expanding the phenotype of sudden cardiac death-An unusual presentation of a family with a Lamin A/C mutation

scientific article published on 8 August 2008

FBN1: The disease-causing gene for Marfan syndrome and other genetic disorders

scientific article

First report of the genetic background of Marfan syndrome in Polish patients.

scientific article

Functional analysis of the anatomical right ventricular components: should assessment of right ventricular function after repair of tetralogy of Fallot be refined?

scientific article published in November 2013

Functional analysis of the common carotid artery: relative distension differences over the vessel wall measured in vivo

scientific article published in May 2004

Gene panel sequencing in heritable thoracic aortic disorders and related entities - results of comprehensive testing in a cohort of 264 patients

scientific article

Genes in Thoracic Aortic Aneurysms and Dissections - Do they Matter?: Translation and Integration of Research and Modern Genetic Techniques into Daily Clinical Practice

scientific article

Genes in thoracic aortic aneurysms/dissections - do they matter?

scientific article published on January 2013

Genetics of left ventricular outflow tract abnormalities.

scientific article

Guía ESC 2015 sobre el tratamiento de la endocarditis infecciosa

Heart failure and sudden cardiac death in heritable thoracic aortic disease caused by pathogenic variants in the SMAD3 gene

article

Heart failure in pregnant women with cardiac disease: data from the ROPAC.

scientific article

In-frame mutations in exon 1 of SKI cause dominant Shprintzen-Goldberg syndrome

scientific article

International Registry of Patients Carrying TGFBR1 or TGFBR2 Mutations: Results of the MAC (Montalcino Aortic Consortium).

scientific article published on 21 November 2016

Intrinsic cardiomyopathy in Marfan syndrome: results from in-vivo and ex-vivo studies of the Fbn1C1039G/+ model and longitudinal findings in humans.

scientific article published on 4 June 2015

Iron deficiency is associated with adverse outcome in Eisenmenger patients

scientific article published on 23 May 2011

Loeys-Dietz syndrome is a specific phenotype and not a concomitant of any mutation in a gene involved in TGF-β signaling

scientific article published in August 2014

Long-Term Outcome of Patients with Perimembranous Ventricular Septal Defect: Results from the Belgian Registry on Adult Congenital Heart Disease.

scientific article

Managing aortic aneurysms and dissections during pregnancy

scientific article published on 17 May 2015

Marfan Syndrome and Related Heritable Thoracic Aortic Aneurysms and Dissections

scientific article published on 25 August 2015

Marfan and Sartans: time to wake up!

scientific article published in June 2015

Mitral valve prolapse syndrome and MASS phenotype: Stability of aortic dilatation but progression of mitral valve prolapse

scientific article

Multiple aneurysms in a patient with aneurysms-osteoarthritis syndrome

scientific article published on 25 December 2012

Myocardial Function, Heart Failure and Arrhythmia in Marfan Syndrome: A Systematic Literature Review

scientific article published on 25 September 2020

New insights into the molecular diagnosis and management of heritable thoracic aortic aneurysms and dissections.

scientific article published on 16 December 2013

Nitric oxide mediates aortic disease in mice deficient in the metalloprotease Adamts1 and in a mouse model of Marfan syndrome.

scientific article published on 9 January 2017

Novel MYH11 and ACTA2 mutations reveal a role for enhanced TGFβ signaling in FTAAD.

scientific article published on 19 September 2011

Organisation of care for pregnancy in patients with congenital heart disease

scientific article

Outflow Through Aortic Side Branches Drives False Lumen Patency in Type B Aortic Dissection

scientific article published on 13 August 2021

Perspectives on the revised Ghent criteria for the diagnosis of Marfan syndrome

scientific article

Phenotypic spectrum of the SMAD3-related aneurysms–osteoarthritis syndrome

article by Ingrid M B H van de Laar et al published 13 December 2011 in Journal of Medical Genetics

Predictive model for late atrial arrhythmia after closure of an atrial septal defect

scientific article published on 29 July 2011

Pregnancy in Women With SMAD3 Mutation

scientific article published on 01 March 2017

Pregnancy outcomes in women with cardiovascular disease: evolving trends over 10 years in the ESC Registry Of Pregnancy And Cardiac disease (ROPAC)

scientific article published on 01 December 2019

Prevalence of Fabry disease in a predominantly hypertensive population with left ventricular hypertrophy

scientific article published on 16 July 2012

Primary impairment of left ventricular function in Marfan syndrome

scientific article

Real-world healthcare utilization in adult congenital heart disease: a systematic review of trends and ratios

scientific article published on 03 May 2019

Reference values for echocardiographic assessment of the diameter of the aortic root and ascending aorta spanning all age categories

scientific article published on 3 July 2014

Relation between genotype and left-ventricular dilatation in patients with Marfan syndrome

article

Right Ventricular Function in Patients With Eisenmenger Syndrome

article

SMAD3 pathogenic variants: risk for thoracic aortic disease and associated complications from the Montalcino Aortic Consortium

scientific article published on 19 January 2019

SMAD4 rare variants in individuals and families with thoracic aortic aneurysms and dissections

scientific article published on 26 February 2019

Sex, pregnancy and aortic disease in Marfan syndrome

scientific article published on 14 July 2017

Short stature, severe aortic root dilation, skin hyperextensibility, extreme joint laxity and craniofacial dysmorphic features: a probable new syndrome

scientific article

Short-term systolic and diastolic ventricular performance after surgical ventricular restoration for dilated ischemic cardiomyopathy

scientific article published on 10 January 2009

Sleep apnea and the impact on cardiovascular risk in patients with Marfan syndrome

scientific article published on 27 June 2019

Spontaneous Right Ventricular Pseudoaneurysms and Increased Arrhythmogenicity in a Mouse Model of Marfan Syndrome

scientific article published on 24 September 2020

Staffing, activities, and infrastructure in 96 specialised adult congenital heart disease clinics in Europe

scientific article published on 26 April 2019

Strain rate imaging detects early cardiac effects of pegylated liposomal Doxorubicin as adjuvant therapy in elderly patients with breast cancer.

scientific article published in December 2008

Successful alcohol septal ablation for late recurrence of left ventricular outflow tract obstruction after surgical myectomy in hypertrophic obstructive cardiomyopathy

scientific article published in April 2008

The 2017 international classification of the Ehlers-Danlos syndromes

scientific article published on March 2017

The Belgian Eisenmenger syndrome registry: implications for treatment strategies?

article

The Ghent Marfan Trial--a randomized, double-blind placebo controlled trial with losartan in Marfan patients treated with β-blockers

scientific article published on 15 January 2011

The expanding cardiovascular phenotype of Marfan syndrome

scientific article published on 23 December 2008

The importance of pulmonary artery pressures on late atrial arrhythmia in transcatheter and surgically closed ASD type secundum.

scientific article published in August 2010

The main pulmonary artery in adults: a controlled multicenter study with assessment of echocardiographic reference values, and the frequency of dilatation and aneurysm in Marfan syndrome

scientific article

The revised Ghent nosology for the Marfan syndrome

scientific article

The spectrum of spontaneous coronary artery dissection: illustrated review of the literature

scientific article published on 28 June 2017

Thoracic aortic-aneurysm and dissection in association with significant mitral valve disease caused by mutations in TGFB2.

scientific article

Three arginine to cysteine substitutions in the pro-alpha (I)-collagen chain cause Ehlers-Danlos syndrome with a propensity to arterial rupture in early adulthood

scientific article

Treatment of pre-existing cardiomyopathy during pregnancy

scientific article

Worsening in oxygen saturation and exercise capacity predict adverse outcome in patients with Eisenmenger syndrome

article

List of works by Julie De Backer

2015 ESC Guidelines for the management of infective endocarditis: The Task Force for the Management of Infective Endocarditis of the European Society of Cardiology (ESC). Endorsed by: European Association for Cardio-Thoracic Surgery (EACTS), the Eur

2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy

A critical analysis of minor cardiovascular criteria in the diagnostic evaluation of patients with Marfan syndrome.

A different view on predictors of pulmonary hypertension in secundum atrial septal defect

A syndrome of altered cardiovascular, craniofacial, neurocognitive and skeletal development caused by mutations in TGFBR1 or TGFBR2

Aggressive cardiovascular phenotype of aneurysms-osteoarthritis syndrome caused by pathogenic SMAD3 variants

Ambulatory Electrocardiographic Monitoring and Ectopic Beat Detection in Conscious Mice

Aneurysm syndromes caused by mutations in the TGF-beta receptor

Aneurysm-osteoarthritis syndrome with visceral and iliac artery aneurysms

Aortic disease in Marfan syndrome is caused by overactivation of sGC-PRKG signaling by NO

Applying massive parallel sequencing to molecular diagnosis of Marfan and Loeys-Dietz syndromes

Arterial hypertension in Turner syndrome: a review of the literature and a practical approach for diagnosis and treatment

Atenolol versus losartan in children and young adults with Marfan's syndrome

Body mass index in adults with congenital heart disease

Cardiovascular Health in Turner Syndrome: A Scientific Statement From the American Heart Association

Cardiovascular imaging in Turner syndrome: state-of-the-art practice across the lifespan

Cardiovascular manifestations in men and women carrying a FBN1 mutation

Case-matched Comparison of Cardiovascular Outcome in Loeys-Dietz Syndrome versus Marfan Syndrome

Characteristics of children and young adults with Marfan syndrome and aortic root dilation in a randomized trial comparing atenolol and losartan therapy

Characterization of cardiovascular involvement in pseudoxanthoma elasticum families

Circulating transforming growth factor-beta in Marfan syndrome

Clinical Validity of Genes for Heritable Thoracic Aortic Aneurysm and Dissection

Clinical and molecular study of 320 children with Marfan syndrome and related type I fibrillinopathies in a series of 1009 probands with pathogenic FBN1 mutations

Comprehensive clinical and molecular assessment of 32 probands with congenital contractural arachnodactyly: report of 14 novel mutations and review of the literature

Comprehensive molecular analysis demonstrates type V collagen mutations in over 90% of patients with classic EDS and allows to refine diagnostic criteria

Design and rationale of a prospective, collaborative meta-analysis of all randomized controlled trials of angiotensin receptor antagonists in Marfan syndrome, based on individual patient data: A report from the Marfan Treatment Trialists' Collaborat

Diagnosis, natural history, and management in vascular Ehlers-Danlos syndrome

Diastolic dysfunction, infarct size, and exercise capacity in remote myocardial infarction: a combined approach of mitral E-wave deceleration time and color M-mode flow propagation velocity

Disproportion and dysmorphism in an adult Belgian population with Turner syndrome: risk factors for chronic diseases?

Echocardiographic methods, quality review, and measurement accuracy in a randomized multicenter clinical trial of Marfan syndrome

Echocardiographically estimated left ventricular end-diastolic and right ventricular systolic pressure in normotensive healthy individuals

Effect of an Abdominal Aortic Aneurysm on Wave Reflection in the Aorta

Effect of celiprolol on prevention of cardiovascular events in vascular Ehlers-Danlos syndrome: a prospective randomised, open, blinded-endpoints trial.

Effects of age, gender, and left ventricular mass on septal mitral annulus velocity (E') and the ratio of transmitral early peak velocity to E' (E/E').

Efficacy of losartan as add-on therapy to prevent aortic growth and ventricular dysfunction in patients with Marfan syndrome: a randomized, double-blind clinical trial

Expanding the phenotype of sudden cardiac death-An unusual presentation of a family with a Lamin A/C mutation

FBN1: The disease-causing gene for Marfan syndrome and other genetic disorders

First report of the genetic background of Marfan syndrome in Polish patients.

Functional analysis of the anatomical right ventricular components: should assessment of right ventricular function after repair of tetralogy of Fallot be refined?

Functional analysis of the common carotid artery: relative distension differences over the vessel wall measured in vivo

Gene panel sequencing in heritable thoracic aortic disorders and related entities - results of comprehensive testing in a cohort of 264 patients

Genes in Thoracic Aortic Aneurysms and Dissections - Do they Matter?: Translation and Integration of Research and Modern Genetic Techniques into Daily Clinical Practice

Genes in thoracic aortic aneurysms/dissections - do they matter?

Genetics of left ventricular outflow tract abnormalities.

Guía ESC 2015 sobre el tratamiento de la endocarditis infecciosa

Heart failure and sudden cardiac death in heritable thoracic aortic disease caused by pathogenic variants in the SMAD3 gene

Heart failure in pregnant women with cardiac disease: data from the ROPAC.

In-frame mutations in exon 1 of SKI cause dominant Shprintzen-Goldberg syndrome

International Registry of Patients Carrying TGFBR1 or TGFBR2 Mutations: Results of the MAC (Montalcino Aortic Consortium).

Intrinsic cardiomyopathy in Marfan syndrome: results from in-vivo and ex-vivo studies of the Fbn1C1039G/+ model and longitudinal findings in humans.

Iron deficiency is associated with adverse outcome in Eisenmenger patients

Loeys-Dietz syndrome is a specific phenotype and not a concomitant of any mutation in a gene involved in TGF-β signaling

Long-Term Outcome of Patients with Perimembranous Ventricular Septal Defect: Results from the Belgian Registry on Adult Congenital Heart Disease.

Managing aortic aneurysms and dissections during pregnancy

Marfan Syndrome and Related Heritable Thoracic Aortic Aneurysms and Dissections

Marfan and Sartans: time to wake up!

Mitral valve prolapse syndrome and MASS phenotype: Stability of aortic dilatation but progression of mitral valve prolapse

Multiple aneurysms in a patient with aneurysms-osteoarthritis syndrome

Myocardial Function, Heart Failure and Arrhythmia in Marfan Syndrome: A Systematic Literature Review

New insights into the molecular diagnosis and management of heritable thoracic aortic aneurysms and dissections.

Nitric oxide mediates aortic disease in mice deficient in the metalloprotease Adamts1 and in a mouse model of Marfan syndrome.

Novel MYH11 and ACTA2 mutations reveal a role for enhanced TGFβ signaling in FTAAD.

Organisation of care for pregnancy in patients with congenital heart disease

Outflow Through Aortic Side Branches Drives False Lumen Patency in Type B Aortic Dissection

Perspectives on the revised Ghent criteria for the diagnosis of Marfan syndrome

Phenotypic spectrum of the SMAD3-related aneurysms–osteoarthritis syndrome

Predictive model for late atrial arrhythmia after closure of an atrial septal defect

Pregnancy in Women With SMAD3 Mutation

Pregnancy outcomes in women with cardiovascular disease: evolving trends over 10 years in the ESC Registry Of Pregnancy And Cardiac disease (ROPAC)

Prevalence of Fabry disease in a predominantly hypertensive population with left ventricular hypertrophy

Primary impairment of left ventricular function in Marfan syndrome

Real-world healthcare utilization in adult congenital heart disease: a systematic review of trends and ratios

Reference values for echocardiographic assessment of the diameter of the aortic root and ascending aorta spanning all age categories

Relation between genotype and left-ventricular dilatation in patients with Marfan syndrome

Right Ventricular Function in Patients With Eisenmenger Syndrome

SMAD3 pathogenic variants: risk for thoracic aortic disease and associated complications from the Montalcino Aortic Consortium

SMAD4 rare variants in individuals and families with thoracic aortic aneurysms and dissections

Sex, pregnancy and aortic disease in Marfan syndrome

Short stature, severe aortic root dilation, skin hyperextensibility, extreme joint laxity and craniofacial dysmorphic features: a probable new syndrome