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List of works by Job de Lange

Abrogation of Wip1 expression by RITA-activated p53 potentiates apoptosis induction via activation of ATM and inhibition of HdmX ⬇️

scientific article published on May 6, 2011

Chk2 mediates RITA-induced apoptosis

scientific article

Defective sister chromatid cohesion is synthetically lethal with impaired APC/C function.

scientific article

ELOF1 is a transcription-coupled DNA repair factor that directs RNA polymerase II ubiquitylation

scientific article published on 09 June 2021

Functional analysis of two inhibitor of apoptosis (iap) orthologs from Helicoverpa armigera nucleopolyhedrovirus

scientific article published on 4 February 2012

HDMX-L is expressed from a functional p53-responsive promoter in the first intron of the HDMX gene and participates in an autoregulatory feedback loop to control p53 activity.

scientific article published on 20 July 2010

High levels of Hdmx promote cell growth in a subset of uveal melanomas ⬇️

scientific article published on August 20, 2012

MDM4 is a key therapeutic target in cutaneous melanoma

scientific article published on 22 July 2012

Non-redundant roles in sister chromatid cohesion of the DNA helicase DDX11 and the SMC3 acetyl transferases ESCO1 and ESCO2

scientific article published on 14 January 2020

Oncogenic functions of hMDMX in in vitro transformation of primary human fibroblasts and embryonic retinoblasts

scientific article published on 12 September 2011

Synergistic growth inhibition based on small-molecule p53 activation as treatment for intraocular melanoma

scientific article

Warsaw Breakage Syndrome associated DDX11 helicase resolves G-quadruplex structures to support sister chromatid cohesion

scientific article published on 27 August 2020

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