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List of works by Guiying Nie

A high-throughput in vitro model of human embryo attachment.

scientific article

A proteomic protocol to identify physiological substrates of pro-protein convertases

scientific article published in January 2011

Acclimation of photosynthetic proteins to rising atmospheric CO2.

scientific article published on March 1994

Activity-modulating monoclonal antibodies to the human serine protease HtrA3 provide novel insights into regulating HtrA proteolytic activities.

scientific article

Application of the wheat-germ cell-free translation system to produce high temperature requirement A3 (HtrA3) proteases

scientific article

Cleavage of endometrial α-integrins into their functional forms is mediated by proprotein convertase 5/6.

scientific article

Complex expression patterns support potential roles for maternally derived activins in the establishment of pregnancy in mouse

scientific article published in November 2006

Complex regulation of decidualization: a role for cytokines and proteases--a review.

scientific article

Construction and application of a multispecific competitor to quantify mRNA of matrix metalloproteinases and their tissue inhibitors in small human biopsies.

scientific article

Cytoskeletal remodelling proteins identified in fetal-maternal interface in pregnant women and rhesus monkeys

scientific article published on 04 March 2011

Decidual HtrA3 negatively regulates trophoblast invasion during human placentation

scientific article published on 14 February 2011

Direct modification of somatotrope function by long-term leptin treatment of primary cultured ovine pituitary cells

scientific article published in December 2001

Distinct expression and localization of serine protease HtrA1 in human endometrium and first-trimester placenta

scientific article published in December 2006

Embryo implantation is closely associated with dynamic expression of proprotein convertase 5/6 in the rabbit uterus.

scientific article

Endometrial CRISP3 is regulated throughout the mouse estrous and human menstrual cycle and facilitates adhesion and proliferation of endometrial epithelial cells

scientific article published on 25 February 2015

Enzyme activity assays within microstructured optical fibers enabled by automated alignment ⬇️

scientific article published on November 20, 2012

Evolutionary conservation of mammalian HTRA3 and its developmental regulation in the rat ovary

scientific journal article

HTRA3 expression in non-pregnant rhesus monkey ovary and endometrium, and at the maternal-fetal interface during early pregnancy

scientific article published on 18 June 2008

HTRA3 is reduced in ovarian cancers regardless of stage

scientific article published on 02 October 2014

High levels of HtrA4 observed in preeclamptic circulation drastically alter endothelial gene expression and induce inflammation in human umbilical vein endothelial cells

scientific article published on 10 September 2016

Hormonal and non-hormonal agents at implantation as targets for contraception

scientific article published on January 1997

HtrA3 Is Downregulated in Cancer Cell Lines and Significantly Reduced in Primary Serous and Granulosa Cell Ovarian Tumors.

scientific article published on February 2013

HtrA3 as an early marker for preeclampsia: specific monoclonal antibodies and sensitive high-throughput assays for serum screening

scientific article

HtrA3 is negatively correlated with lymph node metastasis in invasive ductal breast cancer.

scientific article

HtrA3, a serine protease possessing an IGF-binding domain, is selectively expressed at the maternal-fetal interface during placentation in the mouse

scientific article published on 13 June 2005

Human HtrA4 Expression Is Restricted to the Placenta, Is Significantly Up-Regulated in Early-Onset Preeclampsia, and High Levels of HtrA4 Cause Endothelial Dysfunction

scientific article published on 6 May 2015

IFPA Meeting 2012 Workshop Report III: trophoblast deportation, gestational trophoblastic disease, placental insufficiency and fetal growth restriction, trophoblast over-invasion and accreta-related pathologies, placental thrombosis and fibrinolysis

scientific article published on 17 December 2012

Inhibition of HTRA3 stimulates trophoblast invasion during human placental development

scientific article published on 29 October 2010

Inhibition of embryo implantation in mice through vaginal administration of a proprotein convertase 6 inhibitor

scientific article published on 13 January 2014

Inhibition of proprotein convertase 5/6 activity: potential for nonhormonal women-centered contraception

scientific article published on 12 November 2011

Local regulation of implantation at the human fetal-maternal interface.

scientific article published on January 2010

Multiple Soluble TGF-β Receptors in Addition to Soluble Endoglin Are Elevated in Preeclamptic Serum and They Synergistically Inhibit TGF-β Signaling

scientific article published on 14 June 2017

Newly identified endometrial genes of importance for implantation

scientific article published in January 2002

PC6 levels in uterine lavage are closely associated with uterine receptivity and significantly lower in a subgroup of women with unexplained infertility

scientific article published on 27 January 2011

PEGylation of a proprotein convertase peptide inhibitor for vaginal route of drug delivery: in vitro bioactivity, stability and in vivo pharmacokinetics

scientific article published on 19 September 2012

Placental HtrA3 is regulated by oxygen tension and serum levels are altered during early pregnancy in women destined to develop preeclampsia

scientific article published on 3 November 2010

Podocalyxin promotes an impermeable epithelium and inhibits pro-implantation factors to negatively regulate endometrial receptivity

scientific article published on 14 December 2021

Posttranslational activation of bone morphogenetic protein 2 is mediated by proprotein convertase 6 during decidualization for pregnancy establishment

scientific article published on 16 June 2010

Posttranslational removal of α-dystroglycan N terminus by PC5/6 cleavage is important for uterine preparation for embryo implantation in women

scientific article published on 15 June 2015

Prediction of preeclampsia - a workshop report

scientific article published on 03 December 2007

Presence of active gelatinases in endometrial carcinoma and correlation of matrix metalloproteinase expression with increasing tumor grade and invasion

scientific article published in March 2002

Pro-protein convertases (PCs) other than PC6 are not tightly regulated for implantation in the human endometrium

scientific article published in June 2007

Proprotein convertase 5/6 cleaves platelet-derived growth factor A in the human endometrium in preparation for embryo implantation

scientific article

Proprotein convertase 5/6 is critical for embryo implantation in women: regulating receptivity by cleaving EBP50, modulating ezrin binding, and membrane-cytoskeletal interactions.

scientific article published on 4 October 2011

Proteases at the endometrial-trophoblast interface: their role in implantation.

scientific article

Proteomic approach identifies alterations in cytoskeletal remodelling proteins during decidualization of human endometrial stromal cells.

scientific article

Proteomic identification of caldesmon as a physiological substrate of proprotein convertase 6 in human uterine decidual cells essential for pregnancy establishment

scientific article published in November 2009

Proteomics of the human endometrium and uterine fluid: a pathway to biomarker discovery

scientific article published on 06 October 2012

Requirement for proprotein convertase 5/6 during decidualization of human endometrial stromal cells in vitro

scientific article published on 2 November 2004

Serine peptidase HTRA3 is closely associated with human placental development and is elevated in pregnancy serum

scientific article published on 26 October 2005

Serine protease HtrA1 is developmentally regulated in trophoblast and uterine decidual cells during placental formation in the mouse

scientific article published in July 2005

Serum HtrA1 is differentially regulated between early-onset and late-onset preeclampsia

scientific article published on 8 July 2015

Serum podocalyxin for early detection of preeclampsia at 11-13 weeks of gestation

scientific article published on 02 October 2018

Serum podocalyxin is significantly increased in early-onset preeclampsia and may represent a novel marker of maternal endothelial cell dysfunction

scientific article published on 29 June 2017

Small molecule proprotein convertase inhibitors for inhibition of embryo implantation

scientific article (publication date: 2013)

Society for Reproductive Biology Founders' Lecture 2009. Preparing fertile soil: the importance of endometrial receptivity.

scientific article published in January 2009

Specific and transient up-regulation of proprotein convertase 6 at the site of embryo implantation and identification of a unique transcript in mouse uterus during early pregnancy

scientific article published in February 2003

Suspended core optical fibers for biological applications using UV wavelengths

Uterine Lavage or Aspirate: Which View of the Intrauterine Environment?

scientific article published on 27 April 2012

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