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List of works by Daniele Fachinetti

A genetic memory initiates the epigenetic loop necessary to preserve centromere position

scientific article published on 18 September 2020

A time out for CENP-A.

scientific article published on 17 February 2017

A two-step mechanism for epigenetic specification of centromere identity and function

scientific article

Artificial chromosomes

scientific article published on 24 September 2020

Bimodal activation of BubR1 by Bub3 sustains mitotic checkpoint signaling

scientific article

CDK1-mediated CENP-C phosphorylation modulates CENP-A binding and mitotic kinetochore localization

scientific article published on 01 November 2019

CENP-A Is Dispensable for Mitotic Centromere Function after Initial Centromere/Kinetochore Assembly

scientific article

CENP-A Modifications on Ser68 and Lys124 Are Dispensable for Establishment, Maintenance, and Long-Term Function of Human Centromeres

scientific article published on January 2017

CENP-A overexpression promotes distinct fates in human cells, depending on p53 status

scientific article published on 26 March 2021

Catalytic assembly of the mitotic checkpoint inhibitor BubR1-Cdc20 by a Mad2-induced functional switch in Cdc20.

scientific article published on 20 June 2013

Centromere Dysfunction Compromises Mitotic Spindle Pole Integrity

scientific article published on 05 September 2019

Centromere strength: just a sense of proportion

scientific article published on 07 April 2020

Centromeres are maintained by fastening CENP-A to DNA and directing an arginine anchor-dependent nucleosome transition

scientific article

DNA Sequence-Specific Binding of CENP-B Enhances the Fidelity of Human Centromere Function

scientific article published on May 2015

DNA Sequences in Centromere Formation and Function

scientific article published in January 2017

DNA replication acts as an error correction mechanism to maintain centromere identity by restricting CENP-A to centromeres

scientific article published on 03 June 2019

Exo1 processes stalled replication forks and counteracts fork reversal in checkpoint-defective cells

scientific article published in January 2005

Genome-organizing factors Top2 and Hmo1 prevent chromosome fragility at sites of S phase transcription.

scientific article

Human centromeric CENP-A chromatin is a homotypic, octameric nucleosome at all cell cycle points

scientific article published on 24 February 2017

Human chromosome-specific aneuploidy is influenced by DNA-dependent centromeric features

scientific article published on 21 November 2019

Inducible, reversible system for the rapid and complete degradation of proteins in mammalian cells

scientific article

Keeping the Centromere under Control: A Promising Role for DNA Methylation

scientific article published on 16 August 2019

Kronos scRT: a uniform framework for single-cell replication timing analysis

scientific article published on 28 April 2022

Phosphorylation of CENP-A on serine 7 does not control centromere function

scientific article published in Nature Communications

Plk1 protects kinetochore-centromere architecture against microtubule pulling forces

scientific article published on 30 August 2019

Polo-like kinase 4 controls centriole duplication but does not directly regulate cytokinesis

scientific article

Replicating centromeric chromatin: spatial and temporal control of CENP-A assembly.

scientific article published on 27 April 2012

Replication termination at eukaryotic chromosomes is mediated by Top2 and occurs at genomic loci containing pausing elements

scientific article

Selective Y centromere inactivation triggers chromosome shattering in micronuclei and repair by non-homologous end joining. ⬇️

scientific article published on 05 December 2016

The autoregulated instability of Polo-like kinase 4 limits centrosome duplication to once per cell cycle

scientific article

The dark side of centromeres: types, causes and consequences of structural abnormalities implicating centromeric DNA

scientific article published in Nature Communications

Topoisomerase I poisoning results in PARP-mediated replication fork reversal

scientific article

α-amino trimethylation of CENP-A by NRMT is required for full recruitment of the centromere

scientific article

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