List of works by Paul M O'Byrne

A 43-year-old man with cough, expectoration and recurrent wheezing

scientific article published on December 2016

A GABAergic system in airway epithelium is essential for mucus overproduction in asthma

scientific article

A GM-CSF/IL-33 pathway facilitates allergic airway responses to sub-threshold house dust mite exposure

scientific article

A dual CysLT1/2 antagonist attenuates allergen-induced airway responses in subjects with mild allergic asthma.

scientific article published on 22 July 2016

A golden age of asthma research

scientific article published on 24 December 2020

A new perspective on concepts of asthma severity and control.

scientific article published on September 2008

A nonsteroidal glucocorticoid receptor agonist inhibits allergen-induced late asthmatic responses.

scientific article published in January 2015

A pilot randomised clinical trial of mepolizumab in COPD with eosinophilic bronchitis

scientific article published on 15 March 2017

A role for sensory nerves in the late asthmatic response

scientific article

A summary of the new GINA strategy: a roadmap to asthma control

scientific article (publication date: September 2015)

Acute asthma intervention: insights from the STAY study

scientific article published on 23 April 2007

Acute, but not resolved, influenza A infection enhances susceptibility to house dust mite-induced allergic disease

scientific article

Adding formoterol to budesonide in moderate asthma--health economic results from the FACET study

scientific article published in June 2001

Airway hyperresponsiveness and calcium handling by smooth muscle: a "deeper look".

scientific article published in February 2002

Allergen inhalation challenge in smoking compared with non-smoking asthmatic subjects

scientific article published in June 2011

Allergen inhalation generates pro-inflammatory oxidised phosphatidylcholine associated with airway dysfunction

scientific article published on 03 September 2020

Allergen-Induced Increases in Interleukin-25 and Interleukin-25 Receptor Expression in Mature Eosinophils from Atopic Asthmatics

scientific article published on 30 September 2016

Allergen-induced Changes in Bone Marrow and Airway Dendritic Cells in Subjects with Asthma.

scientific article published on 4 February 2016

Allergen-induced Increases in Sputum Levels of Group 2 Innate Lymphoid Cells in Subjects with Asthma

scientific article published on 19 April 2017

Allergen-induced airway hyperresponsiveness

scientific article published on January 1988

Allergen-induced airway inflammation and its therapeutic intervention

scientific article

Allergen-induced airway responses.

scientific article published on 23 July 2015

Allergen-induced early and late asthmatic responses to inhaled seasonal and perennial allergens.

scientific article published on 26 June 2015

Allergen-induced fluctuation in CC chemokine receptor 3 expression on bone marrow CD34+ cells from asthmatic subjects: significance for mobilization of haemopoietic progenitor cells in allergic inflammation

scientific article published in August 2003

Allergen-induced increases in bone marrow T lymphocytes and interleukin-5 expression in subjects with asthma.

scientific article published in September 2002

An anti-inflammatory drug (BW755C) inhibits airway hyperresponsiveness induced by ozone in dogs

scientific article published on 01 August 1985

An economic evaluation of combination treatment with budesonide and formoterol in patients with mild-to-moderate persistent asthma

scientific article published in November 2004

An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical practice

scientific article published on July 2009

Anti-IgE and Biologic Approaches for the Treatment of Asthma

scientific article

Anti-allergic therapies: effects on eosinophil progenitors.

scientific article

Anti-inflammatory effects of once daily low dose inhaled ciclesonide in mild to moderate asthmatic patients

scientific article published in May 2006

Antisense therapy against CCR3 and the common beta chain attenuates allergen-induced eosinophilic responses

scientific article published on 31 January 2008

Aqueous beclomethasone diproprionate nasal spray: regular versus "as required" use in the treatment of seasonal allergic rhinitis

scientific article

Asthma Management Guidelines: The issue of implementation

scientific article published in February 2006

Asthma and exercise-induced bronchoconstriction in athletes

scientific article

Asthma in the real world

scientific article published in July 2013

Asthma maintenance and reliever therapy

scientific article published in December 2012

Asthma management by monitoring sputum neutrophil count

scientific article published on September 2008

Asthma: management of severe disease

scientific article published on 14 January 2013

Basophil and eosinophil differentiation in allergic reactions

scientific article published on December 1994

Beclomethasone given after the early asthmatic response inhibits the late response and the increased methacholine responsiveness and cromolyn does not

scientific article published in June 1993

Beta2 déjà vu.

scientific article published in January 2006

Biologics and the lung: TSLP and other epithelial cell-derived cytokines in asthma

scientific article published on 27 June 2016

Blood biomarkers of the late phase asthmatic response using RNA-Seq

scholarly article by Amrit Singh et al published 2014 in Allergy, Asthma & Clinical Immunology

Bronchial responsiveness to histamine or methacholine in asthma: measurement and clinical significance

scientific article published on November 1981

Budesonide/formoterol combination therapy as both maintenance and reliever medication in asthma

scientific article

Capsaicin-evoked cough responses in asthmatic patients: Evidence for airway neuronal dysfunction

scientific article

Changes in regulatory B-cell levels in bone marrow, blood, and sputum of patients with asthma following inhaled allergen challenge

scientific article published on 5 December 2017

Cigarette smoke aggravates experimental colitis in rats

scientific article published in October 1999

Circulating Fibrocytes Are an Indicator of Poor Prognosis in Idiopathic Pulmonary Fibrosis

scientific article published in April 2009

Circulating myeloid and plasmacytoid dendritic cells after allergen inhalation in asthmatic subjects

scientific article published in October 2007

Clinical relevance of lipid mediators in asthma.

scientific article

Combination inhaled corticosteroid and long-acting β2-agonist use and severe asthma exacerbations

scientific article published in May 2012

Comparison of the effect of low-dose ciclesonide and fixed-dose fluticasone propionate and salmeterol combination on long-term asthma control

scientific article published on 18 November 2010

Comparison of vilanterol, a novel long-acting beta2 agonist, with placebo and a salmeterol reference arm in asthma uncontrolled by inhaled corticosteroids

scientific article

Conclusion

scientific article published in August 2010

Corrigendum to “Efficacy and safety of fluticasone furoate 100 μg once-daily in patients with persistent asthma: A 24-week placebo and active-controlled randomised trial” [Res Med 108 (2014) 41–49]

article

Corticosteroid-induced gene expression in allergen-challenged asthmatic subjects taking inhaled budesonide.

scientific article

Cysteinyl leukotrienes promote human airway smooth muscle migration

scientific article published in September 2002

Cytokines or their antagonists for the treatment of asthma

scientific article published on July 2006

Daily inhaled corticosteroid treatment should be prescribed for mild persistent asthma. Pro.

scientific article published in August 2005

Decreased miR-192 expression in peripheral blood of asthmatic individuals undergoing an allergen inhalation challenge

scientific article

Design and analytic considerations in determining the cost-effectiveness of early intervention in asthma from a multinational clinical trial.

scientific article

Development and implementation of guidelines in allergic rhinitis - an ARIA-GA2LEN paper

article

Development and validation of a novel risk score for asthma exacerbations: The risk score for exacerbations

scientific article published on 23 September 2014

Development and validation of a questionnaire to measure asthma control.

scientific article published in October 1999

Different profiles of T-cell IFN-gamma and IL-12 in allergen-induced early and dual responders with asthma

scientific article published in May 2005

Diffuse idiopathic pulmonary neuroendocrine hyperplasia, chronic eosinophilic pneumonia, and asthma

scientific article published on 30 November 2009

Does the current stepwise approach to asthma pharmacotherapy encourage over-treatment?

scientific article published on 26 March 2010

Dose-finding evaluation of once-daily treatment with olodaterol, a novel long-acting β2-agonist, in patients with asthma: results of a parallel-group study and a crossover study.

scientific article

EAACI position statement on asthma exacerbations and severe asthma

scientific article

Early intervention of recent onset mild persistent asthma in children aged under 11 yrs: the Steroid Treatment As Regular Therapy in early asthma (START) trial

scientific article published in May 2006

Early intervention with budesonide in mild persistent asthma: a randomised, double-blind trial

scientific article published in March 2003

Effect of ciclesonide dose and duration of therapy on exercise-induced bronchoconstriction in patients with asthma

scientific article published in May 2006

Effect of different asthma treatments on risk of cold-related exacerbations.

scientific article

Effect of inhaled formoterol and budesonide on exacerbations of asthma. Formoterol and Corticosteroids Establishing Therapy (FACET) International Study Group

scientific article

Effect of interferon-gamma on allergic airway responses in interferon-gamma-deficient mice.

scientific article published in August 2002

Effect of low-dose ciclesonide on allergen-induced responses in subjects with mild allergic asthma

scientific article published in August 2005

Effectiveness of early budesonide intervention in Caucasian versus Asian patients with asthma: 3-year results of the START study

scientific article published in November 2006

Effects of Interleukin-13 Blockade on Allergen-induced Airway Responses in Mild Atopic Asthma

scientific article published on 15 April 2011

Effects of an anti-TSLP antibody on allergen-induced asthmatic responses

scientific article published on 20 May 2014

Effects of bidi smoking on all-cause mortality and cardiorespiratory outcomes in men from south Asia: an observational community-based substudy of the Prospective Urban Rural Epidemiology Study (PURE).

scientific article published on February 2017

Effects of budesonide and formoterol on allergen-induced airway responses, inflammation, and airway remodeling in asthma

scientific article published on 6 December 2009

Effects of early intervention with inhaled budesonide on lung function in newly diagnosed asthma.

scientific article published in June 2006

Effects of inhaled ciclesonide on circulating T-helper type 1/T-helper type 2 cells in atopic asthmatics after allergen challenge

scientific article published in November 2006

Effects of inhaled fluticasone propionate on CTLA-4-positive CD4+CD25+ cells in induced sputum in mild asthmatics

scientific article published in November 2008

Effects of intranasal fluticasone and salmeterol on allergen-induced nasal responses

scientific article

Effects of montelukast and budesonide on airway responses and airway inflammation in asthma

scientific article published in November 2002

Efficacy and safety of a CXCR2 antagonist, AZD5069, in patients with uncontrolled persistent asthma: a randomised, double-blind, placebo-controlled trial

scientific article published on 26 August 2016

Efficacy and safety of fluticasone furoate 100 μg once-daily in patients with persistent asthma: A 24-week placebo and active-controlled randomised trial

article

Efficacy and safety of fluticasone furoate/vilanterol compared with fluticasone propionate/salmeterol combination in adult and adolescent patients with persistent asthma: a randomized trial

scientific article published on October 2013

Efficacy and safety of multiple doses of QGE031 (ligelizumab) versus omalizumab and placebo in inhibiting allergen-induced early asthmatic responses

scientific article

Efficacy and safety of once-daily fluticasone furoate 50 mcg in adults with persistent asthma: a 12-week randomized trial

scientific article

Efficacy and safety of tralokinumab in patients with severe uncontrolled asthma: a randomised, double-blind, placebo-controlled, phase 2b trial.

scientific article published on 28 July 2015

Efficacy of budesonide/formoterol maintenance and reliever therapy compared with higher-dose budesonide as step-up from low-dose inhaled corticosteroid treatment.

scientific article

Efficacy of leukotriene receptor antagonists and synthesis inhibitors in asthma.

scientific article published on 16 July 2009

Eicosanoids and asthma

scientific article published on November 1994

Emergency department visits and hospitalisations for asthma, COPD and respiratory tract infections: what is the role of respiratory viruses, and return to school in September, January and March?

scientific article published on 01 October 2020

Emerging monoclonal antibodies as targeted innovative therapeutic approaches to asthma.

scientific article

Epithelial-Derived Cytokines in Asthma

scientific article published on 3 November 2016

Evaluation of single-dose inhaled corticosteroid activity with an allergen challenge model☆☆☆★★★

scientific article published in July 1997

Exhaled nitric oxide in guideline-based asthma management

scientific article published in The Lancet

Expression of IL-33 and TSLP and Their Receptors in Asthmatic Airways after Inhaled Allergen Challenge

scientific article published on 15 September 2018

Extracellular matrix regulates human airway smooth muscle cell migration

scientific article published in October 2004

Fluticasone furoate (FF)/vilanterol (100/25 mcg or 200/25 mcg) or FF (100 mcg) in persistent asthma

scientific article published on 19 August 2015

Fluticasone furoate-vilanterol 100-25 mcg compared with fluticasone furoate 100 mcg in asthma: a randomized trial.

scientific article published on 24 April 2014

Gene-metabolite expression in blood can discriminate allergen-induced isolated early from dual asthmatic responses

scientific article published on 02 July 2013

Global differences in lung function by region (PURE): an international, community-based prospective study

scientific article

Global strategy for asthma management and prevention: GINA executive summary.

scientific article

Glucagon-like peptide-1 receptor expression on human eosinophils and its regulation of eosinophil activation.

scientific article published on 8 December 2016

How much is too much? The treatment of mild asthma

scientific article published in September 2007

IL-10 production in circulating T cells differs between allergen-induced isolated early and dual asthmatic responders

scientific article published in February 2002

IL-25 Receptor Expression on Airway Dendritic Cells after Allergen Challenge in Subjects with Asthma

scientific article published on December 2015

IL-25 and IL-25 receptor expression on eosinophils from subjects with allergic asthma.

scientific article

Identifying Molecular Mechanisms of the Late-Phase Asthmatic Response by Integrating Cellular, Gene, and Metabolite Levels in Blood

scientific article

Immunostimulatory sequences regulate interferon-inducible genes but not allergic airway responses.

scientific article

Impact of mental health and personality traits on the incidence of chronic cough in the Canadian Longitudinal Study on Aging

scientific article published in 2022

In Vitro Airway Responsiveness of Flinders Sensitive and Resistant Line Rats

scientific article published in March 2000

In memoriam: Frederick E Hargreave (1938-2011).

scientific article published on 13 October 2011

In vivo-to-in silico iterations to investigate aeroallergen-host interactions

scientific article

Increased numbers of activated group 2 innate lymphoid cells in the airways of patients with severe asthma and persistent airway eosinophilia.

scientific article published on 17 July 2015

Increased serum levels of soluble IL-18 receptor complex in patients with allergic asthma

scientific article

Increases in airway eosinophils and interleukin-5 with minimal bronchoconstriction during repeated low-dose allergen challenge in atopic asthmatics

scientific article published in April 1998

Increasing doses of inhaled corticosteroids compared to adding long-acting inhaled beta2-agonists in achieving asthma control

scientific article published on 8 August 2008

Induced sputum, bronchoalveolar lavage and blood from mild asthmatics: inflammatory cells, lymphocyte subsets and soluble markers compared

scientific article published in April 1998

Influence of zafirlukast and loratadine on exercise-induced bronchoconstriction

scientific article

Influenza A facilitates sensitization to house dust mite in infant mice leading to an asthma phenotype in adulthood

scientific article published on 31 August 2011

Inhaled allergen bronchoprovocation tests

scientific article published on 11 October 2013

Inhaled beta 2-agonists in the treatment of asthma.

scientific article

Inhaled corticosteroids for asthma: common clinical quandaries.

scientific article

Inhaled corticosteroids/formoterol as a reliever in mild asthma

scientific article published on 30 March 2020

Inhibition of the bronchial response to respiratory heat exchange by increasing doses of terbutaline sulphate.

scientific article

Initiation, dose reduction, and duration of inhaled corticosteroid therapy.

scientific article

Integrated safety and efficacy analysis of once-daily fluticasone furoate for the treatment of asthma

scientific article

Interleukin 10 inhibits lipopolysaccharide-induced survival and cytokine production by human peripheral blood eosinophils

scientific article

Interleukin-18 and interleukin-18 receptor- expression in allergic asthma

scientific article published on 30 September 2011

Interleukin-18 expression, CD8(+) T cells, and eosinophils in lungs of nonsmokers with fatal asthma.

scientific article

Interleukin-5 and allergic inflammation

scientific article published in May 1999

Introduction

scientific article published in August 2010

Leukotriene receptor antagonists for allergic rhinitis: a systematic review and meta-analysis.

scientific article published on March 2004

Lipid mediator serum profiles in asthmatics significantly shift following dietary supplementation with omega-3 fatty acids

scientific article published on 04 July 2013

Lung Homing of Endothelial Progenitor Cells in Humans with Asthma after Allergen Challenge

scientific article published in October 2011

Measuring Eosinophils to Make Treatment Decisions in Asthma

scientific article published in September 2016

Measuring asthma control in group studies: do we need airway calibre and rescue β2-agonist use?

scientific article published in May 2001

Measuring asthma control: a comparison of three classification systems

scientific article published on 28 January 2010

Measuring efficacy and safety of different inhaled corticosteroid preparations☆☆☆★

scientific article published in December 1998

Mediators, airway responsiveness, and asthma.

scientific article published in August 1985

Mepolizumab for prednisone-dependent asthma with sputum eosinophilia

scientific article published in March 2009

Methacholine Challenge: Comparison of Airway Responsiveness Produced by a Vibrating Mesh Nebulizer Versus a Jet Nebulizer

scientific article published on 16 August 2017

Modulation of β1-integrins on hemopoietic progenitor cells after allergen challenge in asthmatic subjects

scientific article published in October 2008

Montelukast Treatment Attenuates the Increase in Myofibroblasts Following Low-Dose Allergen Challenge

scientific article published in September 2006

Morphometric analysis of mouse airways after chronic allergen challenge.

scientific article published in September 2003

Myeloid and plasmacytoid dendritic cells in induced sputum after allergen inhalation in subjects with asthma

scientific article published in July 2010

Myeloid dendritic cells type 2 after allergen inhalation in asthmatic subjects.

scientific article published in July 2014

Myeloid dendritic cells type 2 in allergic asthma

scientific article published on 3 August 2013

Natural regulatory T cells in isolated early responders compared with dual responders with allergic asthma.

scientific article published on 15 October 2013

Nitric oxide in exhaled breath is poorly correlated to sputum eosinophils in patients with prednisone-dependent asthma

scientific article published on August 2010

Normally suppressing CD40 coregulatory signals delivered by airway macrophages to TH2 lymphocytes are defective in patients with atopic asthma.

scientific article

Novel Blood-based Transcriptional Biomarker Panels Predict the Late Phase Asthmatic Response

scientific article published on 31 October 2017

OX40L blockade and allergen-induced airway responses in subjects with mild asthma

scientific article

Obstructive lung disease from conception to old age: differences in the treatment of adults and children with asthma

scientific article published on December 2009

Omalizumab and the immune system: an overview of preclinical and clinical data.

scientific article

Once-daily fluticasone furoate (FF)/vilanterol reduces risk of severe exacerbations in asthma versus FF alone

scientific article

Once-daily fluticasone furoate 50 mcg in mild-to-moderate asthma: a 24-week placebo-controlled randomized trial.

scientific article

Once-daily fluticasone furoate alone or combined with vilanterol in persistent asthma

scientific article published on 17 October 2013

Overall asthma control achieved with budesonide/formoterol maintenance and reliever therapy for patients on different treatment steps.

scientific article

Overall asthma control: the relationship between current control and future risk

scientific article

POINT: Will New Anti-eosinophilic Drugs Be Useful in Asthma Management? Yes.

scientific article published on 6 October 2016

Peripheral blood gene expression changes during allergen inhalation challenge in atopic asthmatic individuals.

scientific article published on 9 February 2012

Pharmacia allergy research foundation and its award for young scientists in allergy research

scientific article published in March 2005

Pharmacological management of mild or moderate persistent asthma

scientific article published on August 2006

Phosphodiesterase-4 inhibition in COPD.

scientific article published in August 2009

Plasma proteomics can discriminate isolated early from dual responses in asthmatic individuals undergoing an allergen inhalation challenge

scientific article

Predictors of a more favourable response to combined therapy with salmeterol and fluticasone as initial maintenance therapy in asthma

scientific article published on 29 September 2007

Progenitor egress from the bone marrow after allergen challenge: role of stromal cell-derived factor 1alpha and eotaxin

scientific article published in March 2005

Prolonged asthmatic responses to inhaled methacholine

scientific article published in April 1983

Prolonged bronchoprotection against inhaled methacholine by inhaled BI 1744, a long-acting beta(2)-agonist, in patients with mild asthma

scientific article published in December 2009

Prolonged protection against exercise-induced bronchoconstriction by the leukotriene D4–receptor antagonist cinalukast☆☆☆★

scientific article published in February 1997

Prostaglandin F2α increases responsiveness of pulmonary airways in dogs

scientific article published in October 1984

Protection by budesonide and fluticasone on allergen-induced airway responses after discontinuation of therapy.

scientific article

Pulmonary function testing in the emergency department and medications prescribed at discharge: results of the Multinational Acute asthma Management, Burden, and Outcomes (MAMBO) study.

scientific article published in June 2010

Rapid response of circulating myeloid dendritic cells to inhaled allergen in asthmatic subjects

scientific article published in June 2002

Reassessing the Th2 cytokine basis of asthma

scientific article published on May 2004

Recent advances in the pathophysiology of asthma

scientific article published on June 2010

Regular use of inhaled albuterol and the allergen-induced late asthmatic response

scientific article published in July 1995

Relationship between quality of life and clinical status in asthma: a factor analysis

scientific article published in February 2004

Repeatability of allergen-induced airway inflammation☆☆☆★

scientific article published in July 1999

Reproducibility of allergen-induced early and late asthmatic responses

scientific article published in June 1995

Respiratory medicine at McMaster University, Hamilton, Ontario: 1968 to 2013.

scientific article published on November 2014

Risks of Long-Acting Beta-Agonists in Achieving Asthma Control

scientific article published on 16 April 2009

Risks of pneumonia in patients with asthma taking inhaled corticosteroids

scientific article published in October 2010

Roflumilast attenuates allergen-induced inflammation in mild asthmatic subjects

scientific article published on 26 October 2011

Roflumilast for asthma: Efficacy findings in non-placebo-controlled comparator and dosing studies.

scientific article

Roflumilast for asthma: Weighing the evidence

scientific article published on 13 August 2015

Role for cysteinyl leukotrienes in allergen-induced change in circulating dendritic cell number in asthma

scientific article published in July 2004

Safety and tolerability of the novel inhaled corticosteroid fluticasone furoate in combination with the β2 agonist vilanterol administered once daily for 52 weeks in patients >=12 years old with asthma: a randomised trial

scientific article published on 25 February 2013

Safety, pharmacodynamics and pharmacokinetics of TPI 1020 in smokers with asthma

scientific article published on 16 March 2009

Severe asthma: future treatments.

scientific article published on May 2012

Severe exacerbations and decline in lung function in asthma

scientific article

Shifting of immune responsiveness to house dust mite by influenza A infection: genomic insights.

scientific article published on 14 December 2011

Should recommendations about starting inhaled corticosteroid treatment for mild asthma be based on symptom frequency: a post-hoc efficacy analysis of the START study

scientific article published on 29 November 2016

Simplified quantitation of myeloid dendritic cells in peripheral blood using flow cytometry

scientific article published in May 2000

Single-dose desloratadine and montelukast and allergen-induced late airway responses

scientific article published on 22 January 2009

Sputum eosinophils and the response of exercise-induced bronchoconstriction to corticosteroid in asthma.

scientific article published on 10 December 2007

Sputum inflammatory cells and allergen-induced airway responses in allergic asthmatic subjects

scientific article published on 30 March 2011

Surfactant Protein-D and Asthma.

scientific article published in May 2016

T helper 17 cells and related cytokines after allergen inhalation challenge in allergic asthmatics.

scientific article published on 4 October 2014

T regulatory cell phenotypes in peripheral blood and bronchoalveolar lavage from non-asthmatic and asthmatic subjects.

scientific article published on 14 July 2015

Targeting Eosinophils in Eosinophilic Granulomatosis with Polyangiitis

scientific article published in May 2017

Th17/Treg ratio derived using DNA methylation analysis discriminates allergen-induced early from dual asthmatic responses

scientific article published on 3 March 2014

Th17/Treg ratio derived using DNA methylation analysis is associated with the late phase asthmatic response

scientific article

The Demise of Anti–IL-5 for Asthma, or Not

scientific article published in December 2007

The Effects of Repeated Bronchoprovocation on FEV1in Subjects with Asthma

scientific article published in October 2015

The Inhaled Steroid Treatment As Regular Therapy in Early Asthma (START) study 5-year follow-up: effectiveness of early intervention with budesonide in mild persistent asthma

scientific article published on 11 April 2008

The Management of Mild Asthma

scientific article published on 22 October 2020

The Potential Role of Aspiration in the Asthmatic Airway

scientific article published on 11 March 2017

The SYGMA programme of phase 3 trials to evaluate the efficacy and safety of budesonide/formoterol given 'as needed' in mild asthma: study protocols for two randomised controlled trials

scientific article published on 10 January 2017

The airway epithelium in childhood asthma

scientific article published in April 2012

The allergen bronchoprovocation model: an important tool for the investigation of new asthma anti-inflammatory therapies

scientific article published on October 2007

The burden of exacerbations in mild asthma: a systematic review

scientific article published on 01 July 2020

The effect of IVX-0142, a heparin-derived hypersulfated disaccharide, on the allergic airway responses in asthma

scientific article published in September 2008

The effect of cysteinyl leukotrienes on growth of eosinophil progenitors from peripheral blood and bone marrow of atopic subjects

scientific article

The effect of montelukast, budesonide alone, and in combination on exercise-induced bronchoconstriction

scientific article published in August 2012

The effect of omega-3 fatty acids on bronchial hyperresponsiveness, sputum eosinophilia, and mast cell mediators in asthma

scientific article

The effect of oral prostaglandin E1 on airway responsiveness in asthmatic subjects

scientific article published in January 1989

The effects of H2-receptor antagonists on exercise refractoriness in asthma

scientific article published in July 1992

The effects of a CXCR1/CXCR2 antagonist on neutrophil migration in mild atopic asthmatic subjects.

scientific article published on 14 September 2016

The effects of an anti-CD11a mAb, efalizumab, on allergen-induced airway responses and airway inflammation in subjects with atopic asthma

scientific article published in August 2003

The effects of an inhaled corticosteroid on oxygen radical production by bronchoalveolar cells after allergen or ozone in dogs

scientific article published in October 1995

The effects of indomethacin on refractoriness following exercise both with and without a bronchoconstrictor response

scientific article published in December 1994

The effects of inhaled budesonide and formoterol in combination and alone when given directly after allergen challenge

scientific article published in February 2007

The effects of inhaled budesonide on lung function in smokers and nonsmokers with mild persistent asthma

scientific article published on 26 August 2009

The effects of intranasal budesonide on allergen-induced production of interleukin-5 and eotaxin, airways, blood, and bone marrow eosinophilia, and eosinophil progenitor expansion in sensitized mice

scientific article

The inhaled Steroid Treatment as Regular Therapy in early asthma (START) study: rationale and design

scientific article published in August 2001

The interaction between bronchoconstriction and cough in asthma.

scientific article published on 24 February 2017

The links between allergen skin test sensitivity, airway responsiveness and airway response to allergen

scientific article published in January 2005

The paradoxes of asthma management: time for a new approach?

scientific article published on 9 September 2017

The pathogenesis of severe asthma: A consensus report from the workshop on pathogenesis

scientific article published in September 1987

The pharmacological modulation of allergen-induced asthma.

scientific article published on 25 October 2012

The poorly explored impact of uncontrolled asthma

scientific article

The promise of electronic data capture in respiratory medicine

scientific article published in February 2011

The reproducibility and sample size requirements of exercise-induced bronchoconstriction measurements

scientific article published in April 2001

The safety of long-acting beta-agonists among patients with asthma using inhaled corticosteroids: systematic review and metaanalysis

scientific article published on 05 September 2008

The utility of methacholine airway responsiveness measurements in evaluating anti-asthma drugs☆☆☆★★★

scientific article published in March 1998

Theophylline does not inhibit allergen-induced increase in airway responsiveness to methacholine.

scientific article

Therapeutic interventions in severe asthma

scientific article

Therapeutic strategies to reduce asthma exacerbations

scientific article published on 29 April 2011

Thymic stromal lymphopoietin and IL-33 modulate migration of hematopoietic progenitor cells in patients with allergic asthma.

scientific article published on 3 February 2015

Timing is everything: Targeting IgE to reduce asthma exacerbation risk.

scientific article published in December 2015

Tiotropium for the treatment of asthma: a drug safety evaluation.

scientific article

Treatment of asthma with drugs modifying the leukotriene pathway.

scientific article

Treatment with anti-OX40L or anti-TSLP does not alter the frequency of T regulatory cells in allergic asthmatics

scientific article published on 27 July 2015

Uniform definition of asthma severity, control, and exacerbations: Document presented for the World Health Organization Consultation on Severe Asthma

article

Urinary leukotriene E4 levels during early and late asthmatic responses†

scientific article published in August 1990