Search filters

List of works by Jürgen Siepmann

A new mathematical model quantifying drug release from bioerodible microparticles using Monte Carlo simulations

scientific article published on 01 December 2002

A new model describing the swelling and drug release kinetics from hydroxypropyl methylcellulose tablets

scientific article published in January 1999

Accelerated ketoprofen release from polymeric matrices: importance of the homogeneity/heterogeneity of excipient distribution

scientific article published on 26 September 2013

Accelerated ketoprofen release from spray-dried polymeric particles: importance of phase transitions and excipient distribution

scientific article published on 28 April 2014

Alginate-poloxamer microparticles for controlled drug delivery to mucosal tissue

scientific article

Bimodal drug release achieved with multi-layer matrix tablets: transport mechanisms and device design

scientific article published in December 2000

Calculation of the dimensions of dosage forms with release controlled by diffusion for in vivo use.

scientific article

Calculation of the dimensions of drug-polymer devices based on diffusion parameters

scientific article published in July 1998

Calculation of the required size and shape of hydroxypropyl methylcellulose matrices to achieve desired drug release profiles

scientific article published in May 2000

Characterization of ethylcellulose: starch-based film coatings for colon targeting.

scientific article published in October 2009

Characterization of moisture-protective polymer coatings using differential scanning calorimetry and dynamic vapor sorption

scientific article published in February 2009

Colon targeting with bacteria-sensitive films adapted to the disease state.

scientific article published on 4 May 2009

Comparative study of vascular prostheses coated with polycyclodextrins for controlled ciprofloxacin release.

scientific article

Cross-linking of chitosan and chitosan/poly(ethylene oxide) beads: a theoretical treatment

scientific article published on 24 February 2007

Cubic phase-forming dry powders for controlled drug delivery on mucosal surfaces

scientific article published on 22 September 2011

Development and evaluation of chitosan and chitosan derivative nanoparticles containing insulin for oral administration.

scientific article published on 26 May 2015

Development of injection moulded matrix tablets based on mixtures of ethylcellulose and low-substituted hydroxypropylcellulose.

scientific article published on 21 February 2009

Diffusion-controlled drug delivery systems: calculation of the required composition to achieve desired release profiles

article

Drug delivery to the upper small intestine window using gastroretentive technologies.

scientific article published on 4 August 2006

Drug release from MCC- and carrageenan-based pellets: experiment and theory.

scientific article published on 22 May 2009

Drug release from extruded solid lipid matrices: Theoretical predictions and independent experiments ⬇️

scientific article published on October 8, 2011

Effect of the size of biodegradable microparticles on drug release: experiment and theory

scientific article published in April 2004

Enzymatically degraded Eurylon 6 HP-PG: ethylcellulose film coatings for colon targeting in inflammatory bowel disease patients

scientific article published on 4 October 2010

Ethionamide boosters. 2. Combining bioisosteric replacement and structure-based drug design to solve pharmacokinetic issues in a series of potent 1,2,4-oxadiazole EthR inhibitors

scientific article

Evaluation of the Efficacy of Dexamethasone-Eluting Electrode Array on the Post-Implant Cochlear Fibrotic Reaction by Three-Dimensional Immunofluorescence Analysis in Mongolian Gerbil Cochlea

scientific article published in 2021

Fenofibrate-loaded PLGA microparticles: effects on ischemic stroke

scientific article published on 9 January 2009

Floating matrix tablets based on low density foam powder: effects of formulation and processing parameters on drug release

scientific article

Floating microparticles based on low density foam powder

scientific article published in July 2002

For the special IJP issue "poorly soluble drugs".

scientific article published on 3 June 2013

Future perspectives in pharmaceutics: contributions from younger scientists. Preface

scientific article published on 25 September 2008

Gentamicin-loaded poly(lactic-co-glycolic acid) microparticles for the prevention of maxillofacial and orthopedic implant infections.

scientific article published on 23 March 2016

HPMC-matrices for controlled drug delivery: a new model combining diffusion, swelling, and dissolution mechanisms and predicting the release kinetics

scientific article

Higuchi equation: derivation, applications, use and misuse.

scientific article published on 31 March 2011

How strongly does trehalose interact with lysozyme in the solid state? Insights from molecular dynamics simulation and inelastic neutron scattering

scientific article published on 29 August 2012

How to improve the storage stability of aqueous polymeric film coatings

scientific article published in November 2007

Hydrophilic matrices for controlled drug delivery: an improved mathematical model to predict the resulting drug release kinetics (the "sequential layer" model).

scientific article published in October 2000

IJP's Editor for the Americas, Australia and New Zealand.

scientific article published in January 2018

Implants for drug substance delivery

scientific article published on 25 January 2017

Importance of glassy-to-rubbery state transitions in moisture-protective polymer coatings

scientific article published on 13 May 2009

In honor of Takeru Higuchi

scientific article published on 26 July 2011

In vitro and in vivo behavior of ground tadalafil hot-melt extrudates: How the carrier material can effectively assure rapid or controlled drug release.

scientific article published on 27 May 2017

In vivo efficacy of microbiota-sensitive coatings for colon targeting: a promising tool for IBD therapy

scientific article

In-silico simulations of advanced drug delivery systems: What will the future offer? ⬇️

scientific article published on July 16, 2013

Influence of urea and guanidine hydrochloride on lysozyme stability and thermal denaturation; a correlation between activity, protein dynamics and conformational changes

scientific article published on 31 August 2010

Injection Molded Capsules for Colon Delivery Combining Time-Controlled and Enzyme-Triggered Approaches

scientific article published on 11 March 2020

Key parameters affecting the initial release (burst) and encapsulation efficiency of peptide-containing poly(lactide-co-glycolide) microparticles

scientific article published on 9 June 2006

Lipids and polymers in pharmaceutical technology: Lifelong companions

scientific article published on 09 January 2019

MALDI-TOF MS imaging of controlled release implants ⬇️

scientific article published on April 19, 2012

Mathematical modeling of bioerodible, polymeric drug delivery systems.

scientific article

Mathematical modeling of controlled drug delivery

scientific article published in June 2001

Mathematical modeling of drug release from bioerodible microparticles: effect of gamma-irradiation

scientific article published in September 2003

Methyl-β-cyclodextrin modified vascular prosthesis: Influence of the modification level on the drug delivery properties in different media.

scientific article

Modeling of diffusion controlled drug delivery ⬇️

scientific article published on October 13, 2011

Multiple unit gastroretentive drug delivery systems: a new preparation method for low density microparticles

scientific article published in May 2003

Non-degradable microparticles containing a hydrophilic and/or a lipophilic drug: preparation, characterization and drug release modeling

scientific article published in March 2003

Novel polymeric film coatings for colon targeting: Drug release from coated pellets.

scientific article published on 5 April 2009

Novel preparation techniques for alginate–poloxamer microparticles controlling protein release on mucosal surfaces ⬇️

scientific article published on December 8, 2011

PLGA implants: How Poloxamer/PEO addition slows down or accelerates polymer degradation and drug release.

scientific article published on 8 March 2017

PLGA-based microparticles: elucidation of mechanisms and a new, simple mathematical model quantifying drug release

scientific article published in May 2002

Peas starch-based film coatings for site-specific drug delivery to the colon

Pharmaceutical Applications of Shellac: Moisture-Protective and Taste-Masking Coatings and Extended-Release Matrix Tablets ⬇️

scientific article (publication date: September 2003)

Polymer blends used for the aqueous coating of solid dosage forms: importance of the type of plasticizer

scientific article published in September 2004

Preparation and investigation of P28GST-loaded PLGA microparticles for immunomodulation of experimental colitis

scientific article published on 15 September 2017

Programmable implants--from pulsatile to controlled release

scientific article published on 23 March 2006

Progress in film coating

scientific article published on 11 October 2013

Protection of moisture-sensitive drugs with aqueous polymer coatings: importance of coating and curing conditions

scientific article published on 27 May 2009

Quaternary polymethacrylate-magnesium aluminum silicate films: molecular interactions, mechanical properties and tackiness

scientific article published on 19 October 2013

Recombinant gelatin hydrogels for the sustained release of proteins

scientific article published on 13 March 2007

Stability of aqueous polymeric controlled release film coatings

scientific article published on 12 October 2013

The 6th world meeting on pharmaceutics, biopharmaceutics and pharmaceutical technology (PBP meeting) April 7-10, 2008, Barcelona, Spain.

scientific article published on 10 July 2008

The effect of gamma-irradiation on drug release from bioerodible microparticles: a quantitative treatment

scientific article published in August 2002

Understanding and predicting drug delivery from hydrophilic matrix tablets using the "sequential layer" model

scientific article published on March 2002

Unintended potential impact of perfect sink conditions on PLGA degradation in microparticles

scientific article published on 05 November 2010

Zinc–alginate microparticles for controlled pulmonary delivery of proteins prepared by spray-drying ⬇️

scientific article published on February 8, 2012

pH-Sensitive polymer blends used as coating materials to control drug release from spherical beads: elucidation of the underlying mass transport mechanisms

scientific article published on 22 July 2005

pH-independent release of a weakly basic drug from water-insoluble and -soluble matrix tablets

scientific article published in June 2000

Paulina is supported by:

About Paulina

Help