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List of works by Matthias Hackl

5.2 Functional -Omics for Cell Lines and Processes: The -Omics Technologies on the Example of CHO Cells

A deletion in the golgi alpha-mannosidase II gene of Caenorhabditis elegans results in unexpected non-wild-type N-glycan structures

scientific article

A screening method to assess biological effects of microRNA overexpression in Chinese hamster ovary cells

scientific article

A signature of 12 microRNAs is robustly associated with growth rate in a variety of CHO cell lines

scientific article published on 15 March 2016

Analysis of microRNA transcription and post-transcriptional processing by Dicer in the context of CHO cell proliferation

scientific article

Annotation of additional evolutionary conserved microRNAs in CHO cells from updated genomic data

scientific article

Association of cardiometabolic microRNAs with COVID-19 severity and mortality

scientific article published on 01 January 2022

CHO microRNA engineering is growing up: recent successes and future challenges

scientific article published on 02 August 2013

Circulating microRNA Signatures in Patients With Idiopathic and Postmenopausal Osteoporosis and Fragility Fractures.

scientific article published on 23 August 2016

Circulating microRNAs as novel biomarkers for bone diseases - Complex signatures for multifactorial diseases?

scientific article published on 22 October 2015

Circulating microRNAs in young individuals with long-duration type 1 diabetes in comparison with healthy controls

scientific article published in 2023

Comprehensive genome and epigenome characterization of CHO cells in response to evolutionary pressures and over time.

scientific article published on 12 April 2016

Computational identification of microRNA gene loci and precursor microRNA sequences in CHO cell lines

scientific article published on 25 January 2012

Conserved MicroRNAs in Chinese hamster ovary cell lines ⬇️

scientific article published on February 1, 2011

Construction of a stability landscape of the CH3 domain of human IgG1 by combining directed evolution with high throughput sequencing

scientific article

Differentially circulating miRNAs after recent osteoporotic fractures can influence osteogenic differentiation.

scientific article

Dynamic mRNA and miRNA profiling of CHO-K1 suspension cell cultures

scientific article published on 5 August 2011

Endogenous microRNA clusters outperform chimeric sequence clusters in Chinese hamster ovary cells

scientific article published on 12 February 2014

Enhanced protein production by microRNA-30 family in CHO cells is mediated by the modulation of the ubiquitin pathway

scientific article published on 6 August 2015

GiSAO.db: a database for ageing research

scientific article

Growth, productivity and protein glycosylation in a CHO EpoFc producer cell line adapted to glutamine-free growth

scientific article published on 9 December 2011

High levels of oncomiR-21 contribute to the senescence-induced growth arrest in normal human cells and its knock-down increases the replicative lifespan

scientific article published on 19 April 2013

Identification of microRNA-mRNA functional interactions in UVB-induced senescence of human diploid fibroblasts

scientific article

Identification of microRNAs specific for high producer CHO cell lines using steady-state cultivation

scientific article

MicroRNA Profiling Reveals Distinct Signatures in Degenerative Rotator Cuff Pathologies

scientific article published on 04 October 2019

MicroRNAs and toxicology: A love marriage

scientific article published on 13 November 2017

MicroRNAs differentially present in the plasma of HIV elite controllers reduce HIV infection in vitro

scientific article

Microarray profiling of preselected CHO host cell subclones identifies gene expression patterns associated with increased production capacity

scientific article published on 24 August 2015

Molecular and cellular effects of in vitro shockwave treatment on lymphatic endothelial cells

scientific article published on 11 December 2014

Next-generation sequencing of the Chinese hamster ovary microRNA transcriptome: Identification, annotation and profiling of microRNAs as targets for cellular engineering

scientific article

One plus one makes three: adding value by co-transfection of anti-apoptotic genes during transient gene expression

article

Prediction of transcribed PIWI-interacting RNAs from CHO RNAseq data

scientific article

Serum miRNA Signatures Are Indicative of Skeletal Fractures in Postmenopausal Women With and Without Type 2 Diabetes and Influence Osteogenic and Adipogenic Differentiation of Adipose Tissue-Derived Mesenchymal Stem Cells In Vitro.

scientific article published on 27 June 2016

Stable overexpression of miR-17 enhances recombinant protein production of CHO cells

scientific article published on 8 February 2014

The CHO miRNA Transcriptome

Transcriptomic changes in CHO cells after adaptation to suspension growth in protein-free medium analysed by a species-specific microarray

scientific article published on 13 March 2017

Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing

scientific article

Upregulation of miR-24 is associated with a decreased DNA damage response upon etoposide treatment in highly differentiated CD8(+) T cells sensitizing them to apoptotic cell death

scientific article

Utilization and evaluation of CHO-specific sequence databases for mass spectrometry based proteomics

scientific article published on 2 March 2012

miR-17, miR-19b, miR-20a, and miR-106a are down-regulated in human aging

scientific article

miRNAs – pathway engineering of CHO cell factories that avoids translational burdening ⬇️

scientific article published on June 4, 2012

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