List of works - Chin-Fu Hsiao

A Bayesian noninferiority approach to evaluation of bridging studies

scientific article published in May 2004

A Phase II Study of Sequential Capecitabine Plus Oxaliplatin Followed by Docetaxel Plus Capecitabine in Patients With Unresectable Gastric Adenocarcinoma: The TCOG 3211 Clinical Trial.

scientific article published on January 2016

A consistency approach to evaluation of bridging studies and multi-regional trials.

scientific article published on 17 May 2011

A group sequential approach to evaluation of bridging studies

scientific article published in November 2003

A polymorphism in the APE1 gene promoter is associated with lung cancer risk

scientific article published on 01 January 2009

A two-stage design for bridging studies.

scientific article published in January 2005

An alternative phase II/III design for continuous endpoints.

scientific article published in March 2011

An approach for sample size determination of average bioequivalence based on interval estimation

scientific article

An autosomal genome-wide scan for loci linked to pre-diabetic phenotypes in nondiabetic Chinese subjects from the Stanford Asia-Pacific Program of Hypertension and Insulin Resistance Family Study

scientific article published in April 2005

An empirical Bayes approach to evaluation of results for a specific region in multiregional clinical trials

scientific article published on 14 January 2013

Analysis of heritability and shared heritability based on genome-wide association studies for thirteen cancer types

journal article published in 2015

Assessing the consistency of the treatment effect under the discrete random effects model in multiregional clinical trials

scientific article published on 2 February 2016

Association of an EGFR intron 1 SNP with never-smoking female lung adenocarcinoma patients

scientific article published on 20 November 2008

Bayesian approach to evaluation of bridging studies.

scientific article published in August 2002

Betel nut chewing and other risk factors associated with obesity among Taiwanese male adults

scientific article published in February 2006

CYP2B6 polymorphisms influence the plasma concentration and clearance of the methadone S-enantiomer

scientific article published in August 2011

Celecoxib plus chemoradiotherapy for locally advanced rectal cancer: a phase II TCOG study

scientific article published on 24 December 2013

Chemokine IP-10 is correlated with cardiac responses and status of infection with HIV and HCV in methadone maintenance patients

scientific article published on 12 May 2015

Circulating interleukin-6 level is a prognostic marker for survival in advanced nonsmall cell lung cancer patients treated with chemotherapy.

scientific article published on 29 October 2012

Clinical experience of the 23-valent capsular polysaccharide pneumococcal vaccination in HIV-1-infected patients receiving highly active antiretroviral therapy: a prospective observational study

scientific article published in May 2004

Clonality and prognostic implications of p53 and epidermal growth factor receptor somatic aberrations in multiple primary lung cancers

scientific article published in January 2007

Clustering of Minimal Deleted Regions Reveals Distinct Genetic Pathways of Human Hepatocellular Carcinoma

scientific article published on 01 May 2004

Comparison of escitalopram and paroxetine in the treatment of major depressive disorder

scientific article

Comparison of serologic responses to vaccination with one dose or two doses of 7-valent pneumococcal conjugate vaccine in HIV-infected adult patients.

scientific article

Comprehensive linkage and linkage heterogeneity analysis of 4344 sibling pairs affected with hypertension from the Family Blood Pressure Program.

scientific article published on April 2007

Correlation between bone mineral density and plasma lipids in Taiwan

scientific article published in August 2003

Definition of three minimal deleted regions by comprehensive allelotyping and mutational screening of FHIT,p16(INK4A), and p19(ARF) genes in nasopharyngeal carcinoma

scientific article

Design and Analysis Issues of Multiregional Clinical Trials with Different Regional Primary Endpoints ⬇️

scientific article published on September 1, 2012

Design and evaluation of multiregional trials with heterogeneous treatment effect across regions.

scientific article published on September 2012

Differences in health-related quality of life between European and Asian patients with hepatocellular carcinoma

scientific article published on April 2016

Discontinuation of secondary prophylaxis for penicilliosis marneffei in AIDS patients responding to highly active antiretroviral therapy

scientific article published in March 2002

EGFR polymorphisms, hormone replacement therapy and lung adenocarcinoma risk: analysis from a genome-wide association study in never-smoking women

scientific article published on 13 December 2012

Endemic fungal infections caused by Cryptococcus neoformans and Penicillium marneffei in patients infected with human immunodeficiency virus and treated with highly active anti-retroviral therapy.

scientific article published in April 2006

Endothelin Type A Receptor Genotype is a Determinant of Quantitative Traits of Metabolic Syndrome in Asian Hypertensive Families: A SAPPHIRe Study

scientific article

Establishing consistency across all regions in a multi-regional clinical trial

scientific article published on 16 April 2012

Estrogen Receptor Gene Polymorphisms and Lung Adenocarcinoma Risk in Never-Smoking Women

scientific article published on 21 August 2015

Etiology of community acquired pneumonia among adult patients requiring hospitalization in Taiwan.

scientific article published on 18 April 2005

Evaluation of experimental designs for two-color cDNA microarrays

scientific article published on 01 November 2005

Final results of a randomized phase III trial of induction chemotherapy followed by concurrent chemoradiotherapy versus concurrent chemoradiotherapy alone in patients with stage IVA and IVB nasopharyngeal carcinoma-Taiwan Cooperative Oncology Group

scientific article published on 01 September 2018

Functional genetic polymorphisms in CYP2C19 gene in relation to cardiac side effects and treatment dose in a methadone maintenance cohort.

scientific article published on 09 September 2013

Genetic Modifiers of Progression-Free Survival in Never-Smoking Lung Adenocarcinoma Patients Treated with First-Line Tyrosine Kinase Inhibitors

scientific article

Genetic polymorphisms in CYP3A4 are associated with withdrawal symptoms and adverse reactions in methadone maintenance patients

scientific article published on 8 September 2011

Genetic polymorphisms in the opioid receptor mu1 gene are associated with changes in libido and insomnia in methadone maintenance patients.

scientific article published on 9 March 2012

Genetic variants of human urea transporter-2 are associated with metabolic syndrome in Asian population.

scientific article published on 23 August 2010

Genetic variation in aldosterone synthase predicts plasma glucose levels ⬇️

scientific article published on October 30, 2001

Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia

scientific journal article

Genome-wide linkage analysis of lipids in nondiabetic Chinese and Japanese from the SAPPHIRe family study

scientific article

Genomewide loss of heterozygosity and its clinical associations in non small cell lung cancer

scientific article published on 01 November 2005

Herpes zoster in HIV-1-infected patients in the era of highly active antiretroviral therapy: a prospective observational study

scientific article published in October 2005

Hormone replacement therapy and lung cancer risk in Chinese.

scientific article published in October 2007

Impact of chronic hepatitis B virus (HBV) infection on outcomes of patients infected with HIV in an area where HBV infection is hyperendemic

scientific article published on 28 April 2004

Impact of chronic hepatitis C infection on outcomes of patients with an advanced stage of HIV-1 infection in an area of low prevalence of co-infection

article

Impaired Chromatin Remodeling Predicts Better Survival to Modified Gemcitabine and S-1 plus Nivolumab in Advanced Biliary Tract Cancer: A Phase II T1219 Study

scientific article published in 2022

Improved outcomes of HIV-1-infected adults with tuberculosis in the era of highly active antiretroviral therapy

scientific article published in December 2003

Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33

journal article published in 2014

Increased risk for Entamoeba histolytica infection and invasive amebiasis in HIV seropositive men who have sex with men in Taiwan

scientific article

Insulin resistance: regression and clustering

scientific article (publication date: 2014)

Intake of potassium- and magnesium-enriched salt improves functional outcome after stroke: a randomized, multicenter, double-blind controlled trial

scientific article published on 6 September 2017

Integrated care for geriatric frailty and sarcopenia: a randomized control trial.

scientific article published on 26 August 2016

Interactions between household air pollution and GWAS-identified lung cancer susceptibility markers in the Female Lung Cancer Consortium in Asia (FLCCA).

scientific article published on 8 January 2015

Interactive effect of cigarette smoking with human 8-oxoguanine DNA N-glycosylase 1 (hOGG1) polymorphisms on the risk of lung cancer: a case-control study in Taiwan

scientific article published on 11 August 2009

International cross-cultural field validation of an European Organization for Research and Treatment of Cancer questionnaire module for patients with primary liver cancer, the European Organization for Research and Treatment of Cancer quality-of-lif

scientific article published in March 2012

Isolated Antibody to Hepatitis B Core Antigen in Individuals Infected with HIV-1

article

Long-term results of a randomized, observation-controlled, phase III trial of adjuvant interferon Alfa-2b in hepatocellular carcinoma after curative resection

scientific article

Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women

scientific article

Methicillin-resistant Staphylococcus aureus carriage, infection and transmission in dialysis patients, healthcare workers and their family members

scientific article published on 19 November 2007

Mixed noninferiority margin and statistical tests in active controlled trials

scientific article published on 01 January 2007

Non-lethal Candida albicans cph1/cph1 efg1/efg1 mutant partially protects mice from systemic infections by lethal wild-type cells

scientific article published on 16 December 2008

OPRM1 genetic polymorphisms are associated with the plasma nicotine metabolite cotinine concentration in methadone maintenance patients: a cross sectional study.

scientific article published on 6 December 2012

PXR polymorphisms interacted with CYP2B6 polymorphisms on methadone metabolites

scientific article published on 01 February 2013

Physical inactivity is an important lifestyle determinant of insulin resistance in hypertensive patients

scientific article

Polymorphisms of MLH1 and MSH2 genes and the risk of lung cancer among never smokers

scientific article published on 19 November 2010

Prevalence of Toxoplasma gondii infection and incidence of toxoplasma encephalitis in non-haemophiliac HIV-1-infected adults in Taiwan

article

Proposals of statistical consideration to evaluation of results for a specific region in multi-regional trials--Asian perspective.

scientific article published in July 2010

Quality of life changes in patients undergoing treatment for hepatocellular carcinoma.

scientific article published on 6 May 2015

Randomised clinical trial: comparison of two everolimus dosing schedules in patients with advanced hepatocellular carcinoma.

scientific article

Recurrence of tuberculosis in HIV-1-infected adults treated after rifamycin-based treatment and highly active antiretroviral therapy.

scientific article

Risk factors for primary lung cancer among never smokers by gender in a matched case-control study.

scientific article published on 22 May 2012

Risk of recurrent non-typhoid Salmonella bacteraemia after early discontinuation of ciprofloxacin as secondary prophylaxis in AIDS patients in the era of highly active antiretroviral therapy.

scientific article published in March 2001

Risk of recurrent nontyphoid Salmonella bacteremia in HIV-infected patients in the era of highly active antiretroviral therapy and an increasing trend of fluoroquinolone resistance

scientific article published on 19 July 2007

Sagittal abdominal diameter is associated with insulin sensitivity in Chinese hypertensive patients and their siblings

scientific article published in March 2003

Sample size determination for a specific region in a multiregional trial.

scientific article published in July 2010

Sample size determination for a specific region in multiregional clinical trials with multiple co-primary endpoints.

scientific article

Sample size determination for individual bioequivalence inference

scientific article

Sample size estimation of multiregional clinical trials with heterogeneous variability across regions

scientific article

Statistical methods for bridging studies.

scientific article published on September 2012

Statistical test for evaluation of biosimilarity in variability of follow-on biologics.

scientific article published on January 2010

Surrogate estimates of insulin sensitivity in subjects with hypertension.

scientific article published on 18 January 2007

The association of genetic polymorphisms in the κ-opioid receptor 1 gene with body weight, alcohol use, and withdrawal symptoms in patients with methadone maintenance

scientific article

The effects of the renin-angiotensin-aldosterone system gene polymorphisms on insulin resistance in hypertensive families

scientific article

The insulin sensitivity, glucose effectiveness and acute insulin response to glucose load of non-obese adolescent type 2 diabetes

scientific article published in December 2004

The insulin sensitivity, glucose sensitivity, and acute insulin response to glucose load in adolescent type 2 diabetes in Taiwanese

scientific article published in January 2006

Trends of mortality and causes of death among HIV-infected patients in Taiwan, 1984-2005.

scientific article published on 28 June 2008

UGT2B7 genetic polymorphisms are associated with the withdrawal symptoms in methadone maintenance patients.

scientific article published in June 2012

Use of a Bayesian approach in the design and evaluation of NCE2s.

scientific article published on 19 September 2017

Use of a two-sided tolerance interval in the design and evaluation of biosimilarity in clinical studies

scientific article published on 01 September 2020

Use of interval estimations in design and evaluation of multiregional clinical trials with continuous outcomes.

scientific article published in January 2018

Use of prior information for Bayesian evaluation of bridging studies

scientific article published in January 2007

Use of tolerance intervals for assessing biosimilarity

scientific article published on 04 August 2020

Waist circumference predicts metabolic cardiovascular risk in postmenopausal Chinese women

scientific article

List of works by Chin-Fu Hsiao

A Bayesian noninferiority approach to evaluation of bridging studies

A Phase II Study of Sequential Capecitabine Plus Oxaliplatin Followed by Docetaxel Plus Capecitabine in Patients With Unresectable Gastric Adenocarcinoma: The TCOG 3211 Clinical Trial.

A consistency approach to evaluation of bridging studies and multi-regional trials.

A group sequential approach to evaluation of bridging studies

A polymorphism in the APE1 gene promoter is associated with lung cancer risk

A two-stage design for bridging studies.

An alternative phase II/III design for continuous endpoints.

An approach for sample size determination of average bioequivalence based on interval estimation

An autosomal genome-wide scan for loci linked to pre-diabetic phenotypes in nondiabetic Chinese subjects from the Stanford Asia-Pacific Program of Hypertension and Insulin Resistance Family Study

An empirical Bayes approach to evaluation of results for a specific region in multiregional clinical trials

Analysis of heritability and shared heritability based on genome-wide association studies for thirteen cancer types

Assessing the consistency of the treatment effect under the discrete random effects model in multiregional clinical trials

Association of an EGFR intron 1 SNP with never-smoking female lung adenocarcinoma patients

Bayesian approach to evaluation of bridging studies.

Betel nut chewing and other risk factors associated with obesity among Taiwanese male adults

CYP2B6 polymorphisms influence the plasma concentration and clearance of the methadone S-enantiomer

Celecoxib plus chemoradiotherapy for locally advanced rectal cancer: a phase II TCOG study

Chemokine IP-10 is correlated with cardiac responses and status of infection with HIV and HCV in methadone maintenance patients

Circulating interleukin-6 level is a prognostic marker for survival in advanced nonsmall cell lung cancer patients treated with chemotherapy.

Clinical experience of the 23-valent capsular polysaccharide pneumococcal vaccination in HIV-1-infected patients receiving highly active antiretroviral therapy: a prospective observational study

Clonality and prognostic implications of p53 and epidermal growth factor receptor somatic aberrations in multiple primary lung cancers

Clustering of Minimal Deleted Regions Reveals Distinct Genetic Pathways of Human Hepatocellular Carcinoma

Comparison of escitalopram and paroxetine in the treatment of major depressive disorder

Comparison of serologic responses to vaccination with one dose or two doses of 7-valent pneumococcal conjugate vaccine in HIV-infected adult patients.

Comprehensive linkage and linkage heterogeneity analysis of 4344 sibling pairs affected with hypertension from the Family Blood Pressure Program.

Correlation between bone mineral density and plasma lipids in Taiwan

Definition of three minimal deleted regions by comprehensive allelotyping and mutational screening of FHIT,p16(INK4A), and p19(ARF) genes in nasopharyngeal carcinoma

Design and Analysis Issues of Multiregional Clinical Trials with Different Regional Primary Endpoints ⬇️

Design and evaluation of multiregional trials with heterogeneous treatment effect across regions.

Differences in health-related quality of life between European and Asian patients with hepatocellular carcinoma

Discontinuation of secondary prophylaxis for penicilliosis marneffei in AIDS patients responding to highly active antiretroviral therapy

EGFR polymorphisms, hormone replacement therapy and lung adenocarcinoma risk: analysis from a genome-wide association study in never-smoking women

Endemic fungal infections caused by Cryptococcus neoformans and Penicillium marneffei in patients infected with human immunodeficiency virus and treated with highly active anti-retroviral therapy.

Endothelin Type A Receptor Genotype is a Determinant of Quantitative Traits of Metabolic Syndrome in Asian Hypertensive Families: A SAPPHIRe Study

Establishing consistency across all regions in a multi-regional clinical trial

Estrogen Receptor Gene Polymorphisms and Lung Adenocarcinoma Risk in Never-Smoking Women

Etiology of community acquired pneumonia among adult patients requiring hospitalization in Taiwan.

Evaluation of experimental designs for two-color cDNA microarrays

Final results of a randomized phase III trial of induction chemotherapy followed by concurrent chemoradiotherapy versus concurrent chemoradiotherapy alone in patients with stage IVA and IVB nasopharyngeal carcinoma-Taiwan Cooperative Oncology Group

Functional genetic polymorphisms in CYP2C19 gene in relation to cardiac side effects and treatment dose in a methadone maintenance cohort.

Genetic Modifiers of Progression-Free Survival in Never-Smoking Lung Adenocarcinoma Patients Treated with First-Line Tyrosine Kinase Inhibitors

Genetic polymorphisms in CYP3A4 are associated with withdrawal symptoms and adverse reactions in methadone maintenance patients

Genetic polymorphisms in the opioid receptor mu1 gene are associated with changes in libido and insomnia in methadone maintenance patients.

Genetic variants of human urea transporter-2 are associated with metabolic syndrome in Asian population.

Genetic variation in aldosterone synthase predicts plasma glucose levels ⬇️

Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia

Genome-wide linkage analysis of lipids in nondiabetic Chinese and Japanese from the SAPPHIRe family study

Genomewide loss of heterozygosity and its clinical associations in non small cell lung cancer

Herpes zoster in HIV-1-infected patients in the era of highly active antiretroviral therapy: a prospective observational study

Hormone replacement therapy and lung cancer risk in Chinese.

Impact of chronic hepatitis B virus (HBV) infection on outcomes of patients infected with HIV in an area where HBV infection is hyperendemic

Impact of chronic hepatitis C infection on outcomes of patients with an advanced stage of HIV-1 infection in an area of low prevalence of co-infection

Impaired Chromatin Remodeling Predicts Better Survival to Modified Gemcitabine and S-1 plus Nivolumab in Advanced Biliary Tract Cancer: A Phase II T1219 Study

Improved outcomes of HIV-1-infected adults with tuberculosis in the era of highly active antiretroviral therapy

Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33

Increased risk for Entamoeba histolytica infection and invasive amebiasis in HIV seropositive men who have sex with men in Taiwan

Insulin resistance: regression and clustering

Intake of potassium- and magnesium-enriched salt improves functional outcome after stroke: a randomized, multicenter, double-blind controlled trial

Integrated care for geriatric frailty and sarcopenia: a randomized control trial.

Interactions between household air pollution and GWAS-identified lung cancer susceptibility markers in the Female Lung Cancer Consortium in Asia (FLCCA).

Interactive effect of cigarette smoking with human 8-oxoguanine DNA N-glycosylase 1 (hOGG1) polymorphisms on the risk of lung cancer: a case-control study in Taiwan

International cross-cultural field validation of an European Organization for Research and Treatment of Cancer questionnaire module for patients with primary liver cancer, the European Organization for Research and Treatment of Cancer quality-of-lif

Isolated Antibody to Hepatitis B Core Antigen in Individuals Infected with HIV-1

Long-term results of a randomized, observation-controlled, phase III trial of adjuvant interferon Alfa-2b in hepatocellular carcinoma after curative resection

Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women

Methicillin-resistant Staphylococcus aureus carriage, infection and transmission in dialysis patients, healthcare workers and their family members

Mixed noninferiority margin and statistical tests in active controlled trials

Non-lethal Candida albicans cph1/cph1 efg1/efg1 mutant partially protects mice from systemic infections by lethal wild-type cells

OPRM1 genetic polymorphisms are associated with the plasma nicotine metabolite cotinine concentration in methadone maintenance patients: a cross sectional study.

PXR polymorphisms interacted with CYP2B6 polymorphisms on methadone metabolites

Physical inactivity is an important lifestyle determinant of insulin resistance in hypertensive patients

Polymorphisms of MLH1 and MSH2 genes and the risk of lung cancer among never smokers

Prevalence of Toxoplasma gondii infection and incidence of toxoplasma encephalitis in non-haemophiliac HIV-1-infected adults in Taiwan

Proposals of statistical consideration to evaluation of results for a specific region in multi-regional trials--Asian perspective.

Quality of life changes in patients undergoing treatment for hepatocellular carcinoma.

Randomised clinical trial: comparison of two everolimus dosing schedules in patients with advanced hepatocellular carcinoma.

Recurrence of tuberculosis in HIV-1-infected adults treated after rifamycin-based treatment and highly active antiretroviral therapy.

Risk factors for primary lung cancer among never smokers by gender in a matched case-control study.

Risk of recurrent non-typhoid Salmonella bacteraemia after early discontinuation of ciprofloxacin as secondary prophylaxis in AIDS patients in the era of highly active antiretroviral therapy.