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List of works by Simona Paladino

Analysis of detergent-resistant membranes associated with apical and basolateral GPI-anchored proteins in polarized epithelial cells

scientific article published on 20 September 2006

Anandamide inhibits the Wnt/β-catenin signalling pathway in human breast cancer MDA MB 231 cells.

scientific article

Calcium levels in the Golgi complex regulate clustering and apical sorting of GPI-APs in polarized epithelial cells

scientific article published in 2021

Caveolin transfection results in caveolae formation but not apical sorting of glycosylphosphatidylinositol (GPI)-anchored proteins in epithelial cells.

scientific article

Characterization of the Properties and Trafficking of an Anchorless Form of the Prion Protein

scientific article published in Journal of Biological Chemistry

Convergent Effects of Resveratrol and PYK2 on Prostate Cells.

scientific article published on 13 September 2016

Detergent-resistant membrane domains but not the proteasome are involved in the misfolding of a PrP mutant retained in the endoplasmic reticulum

scientific article published on February 2006

Different GPI-attachment signals affect the oligomerisation of GPI-anchored proteins and their apical sorting.

scientific article

Differential recognition of a tyrosine-dependent signal in the basolateral and endocytic pathways of thyroid epithelial cells

scientific article published in April 2002

EGFR activation triggers cellular hypertrophy and lysosomal disease in NAGLU-depleted cardiomyoblasts, mimicking the hallmarks of mucopolysaccharidosis IIIB.

scientific article published on 18 January 2018

Endoplasmic reticulum stress reduces the export from the ER and alters the architecture of post-ER compartments

scientific article

FBXW7 and USP7 regulate CCDC6 turnover during the cell cycle and affect cancer drugs susceptibility in NSCLC.

scientific article published in May 2015

Functional interaction between p75NTR and TrkA: the endocytic trafficking of p75NTR is driven by TrkA and regulates TrkA-mediated signalling

scientific article published on January 2005

Genotype-Phenotype Correlations in Neurofibromatosis Type 1: Identification of Novel and Recurrent NF1 Gene Variants and Correlations with Neurocognitive Phenotype

scientific article published in 2022

Golgi sorting regulates organization and activity of GPI proteins at apical membranes

scientific article

Identification of sumoylation sites in CCDC6, the first identified RET partner gene in papillary thyroid carcinoma, uncovers a mode of regulating CCDC6 function on CREB1 transcriptional activity

scientific article

Lipid rafts and clathrin cooperate in the internalization of PrP in epithelial FRT cells

scientific article

Localization of neuroglobin in the brain of R6/2 mouse model of Huntington's disease

scientific article published on 3 November 2017

Metformin restores the mitochondrial network and reverses mitochondrial dysfunction in Down syndrome cells

scientific article published on 13 January 2017

Molecular determinants of ER-Golgi contacts identified through a new FRET-FLIM system

scientific article published on 18 January 2019

N- and O-glycans are not directly involved in the oligomerization and apical sorting of GPI proteins

scientific article published on 6 September 2008

N-Glycosylation instead of cholesterol mediates oligomerization and apical sorting of GPI-APs in FRT cells

scientific article

N6-isopentenyladenosine improves nuclear shape in fibroblasts from humans with progeroid syndromes by inhibiting the farnesylation of prelamin A.

scientific article published on 18 November 2013

New therapeutic perspectives in CCDC6 deficient lung cancer cells

scientific article published on 24 October 2014

Oligomerization is a specific requirement for apical sorting of glycosyl-phosphatidylinositol-anchored proteins but not for non-raft-associated apical proteins

scientific article published on March 2007

Organization of GPI-anchored proteins at the cell surface and its physiopathological relevance

scientific article published on 24 July 2018

PrP(C) association with lipid rafts in the early secretory pathway stabilizes its cellular conformation

scientific article published on 30 June 2004

PrPC is sorted to the basolateral membrane of epithelial cells independently of its association with rafts

scientific article published on November 2002

Protein oligomerization modulates raft partitioning and apical sorting of GPI-anchored proteins

scientific article

Regulation of sub-compartmental targeting and folding properties of the Prion-like protein Shadoo

scientific article

Resveratrol couples apoptosis with autophagy in UVB-irradiated HaCaT cells

scientific article (publication date: 2013)

Selective roles for cholesterol and actin in compartmentalization of different proteins in the Golgi and plasma membrane of polarized cells

scientific article published on 12 August 2008

TRAP1 and the proteasome regulatory particle TBP7/Rpt3 interact in the endoplasmic reticulum and control cellular ubiquitination of specific mitochondrial proteins

scientific article published on 7 October 2011

Targeting Mitochondrial Network Architecture in Down Syndrome and Aging

scientific article published on 29 April 2020

Trafficking and Membrane Organization of GPI-Anchored Proteins in Health and Diseases

scientific article published on 15 April 2015

Translational control in the stress adaptive response of cancer cells: a novel role for the heat shock protein TRAP1

scientific article

Wilson disease protein ATP7B utilizes lysosomal exocytosis to maintain copper homeostasis.

scientific article published on 5 June 2014

ZSCAN4+ mouse embryonic stem cells have an oxidative and flexible metabolic profile

scientific article published on 18 May 2020