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List of works by Newton G Castro

A novel agonist binding site on nicotinic acetylcholine receptors

scientific article published in January 1993

Altered oxygen metabolism associated to neurogenesis of induced pluripotent stem cells derived from a schizophrenic patient

scientific article published in January 2012

Astrocyte transforming growth factor beta 1 promotes inhibitory synapse formation via CaM kinase II signaling

scientific article published on 10 July 2014

Astrocyte-induced synaptogenesis is mediated by transforming growth factor β signaling through modulation of D-serine levels in cerebral cortex neurons

scientific article

Binding of [3H]MK-801 in subcellular fractions of Schistosoma mansoni: evidence for interaction with nicotinic receptors

scientific article published in May 2005

Brief-lifetime, fast-inactivating ion channels account for the alpha-bungarotoxin-sensitive nicotinic response in hippocampal neurons

scientific article published on 01 December 1993

CNS-selective noncompetitive cholinesterase inhibitors derived from the natural piperidine alkaloid (-)-spectaline

scientific article

Cardanol-derived AChE inhibitors: Towards the development of dual binding derivatives for Alzheimer's disease

scientific article published on 17 December 2015

Characterization of a new synthetic isoflavonoid with inverse agonist activity at the central benzodiazepine receptor

scientific article published in July 2004

Choline and acetylcholine have similar kinetic properties of activation and desensitization on the alpha7 nicotinic receptors in rat hippocampal neurons

scientific article published on 01 November 2000

Colchicine inhibits cationic dye uptake induced by ATP in P2X2 and P2X7 receptor-expressing cells: implications for its therapeutic action

scientific article

Design, Synthesis and Biological Evaluation of Novel Triazole N-acylhydrazone Hybrids for Alzheimer's Disease

scientific article published on 10 July 2020

Design, synthesis and evaluation of novel feruloyl-donepezil hybrids as potential multitarget drugs for the treatment of Alzheimer's disease.

scientific article published on 21 February 2017

Design, synthesis and pharmacological evaluation of N-benzyl-piperidinyl-aryl-acylhydrazone derivatives as donepezil hybrids: Discovery of novel multi-target anti-alzheimer prototype drug candidates.

scientific article published on 31 January 2018

Design, synthesis, and evaluation of guanylhydrazones as potential inhibitors or reactivators of acetylcholinesterase.

scientific article

Direct inhibition of the N-methyl-D-aspartate receptor channel by dopamine and (+)-SKF38393.

scientific article published on April 1999

Dopamine promotes NMDA receptor hypofunction in the retina through D1 receptor-mediated Csk activation, Src inhibition and decrease of GluN2B phosphorylation.

scientific article published on 18 January 2017

Effects of combined 5-HT2A and cannabinoid receptor modulation on a schizophrenia-related prepulse inhibition deficit in mice

scientific article published on 24 February 2020

Erythrina mulungu alkaloids are potent inhibitors of neuronal nicotinic receptor currents in mammalian cells

scientific article

Geissospermum vellosii stembark: anticholinesterase activity and improvement of scopolamine-induced memory deficits.

scientific article

Generation of iPSC-Derived Human Peripheral Sensory Neurons Releasing Substance P Elicited by TRPV1 Agonists

scientific article published on 22 August 2018

LASSBio-881: an N-acylhydrazone transient receptor potential vanilloid subfamily type 1 antagonist orally effective against the hypernociception induced by capsaicin or partial sciatic ligation

scientific article

Low concentrations of pyridostigmine prevent soman-induced inhibition of GABAergic transmission in the central nervous system: involvement of muscarinic receptors

scientific article

Mitomycin-treated undifferentiated embryonic stem cells as a safe and effective therapeutic strategy in a mouse model of Parkinson's disease

scientific article

New potential AChE inhibitor candidates.

scientific article published on 16 April 2009

New selective acetylcholinesterase inhibitors designed from natural piperidine alkaloids

scientific article published in July 2005

Nicotinic receptor function in the mammalian central nervous system

scientific article

Novel 6-methanesulfonamide-3,4-methylenedioxyphenyl-N-acylhydrazones: orally effective anti-inflammatory drug candidates

scientific article published on 25 December 2008

Spine density and dendritic branching pattern of hippocampal CA1 pyramidal neurons in neonatal rats chronically exposed to the organophosphate paraoxon

scientific article published on March 2004

Stereoselective synthesis and preliminary evaluation of new D-3-heteroarylcarbonylalanines as ligands of the NMDA receptor

scientific article published in September 2004

Synthesis and preliminary pharmacological evaluation of new (+/-) 1,4-naphthoquinones structurally related to lapachol.

scientific article

The magnitude of alpha7 nicotinic receptor currents in rat hippocampal neurons is dependent upon GABAergic activity and depolarization

scientific article published on 12 July 2006

Zika virus replicates in adult human brain tissue and impairs synapses and memory in mice

scientific article published on 05 September 2019

alpha-Bungarotoxin-sensitive hippocampal nicotinic receptor channel has a high calcium permeability

scientific article published on February 1995

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