List of works - Li Huang

Activation and inhibition of the proteasome by betulinic acid and its derivatives

scientific article

Anti-AIDS agents 79. Design, synthesis, molecular modeling and structure-activity relationships of novel dicamphanoyl-2',2'-dimethyldihydropyranochromone (DCP) analogs as potent anti-HIV agents.

scientific article

Anti-AIDS agents 81. Design, synthesis, and structure-activity relationship study of betulinic acid and moronic acid derivatives as potent HIV maturation inhibitors

scientific article

Anti-AIDS agents 85. Design, synthesis, and evaluation of 1R,2R-dicamphanoyl-3,3-dimethyldihydropyrano-[2,3-c]xanthen-7(1H)-one (DCX) derivatives as novel anti-HIV agents.

scientific article published on 20 October 2011

Anti-AIDS agents 90. novel C-28 modified bevirimat analogues as potent HIV maturation inhibitors.

scientific article

Anti-AIDS agents. 78. Design, synthesis, metabolic stability assessment, and antiviral evaluation of novel betulinic acid derivatives as potent anti-human immunodeficiency virus (HIV) agents

scientific article published on May 2009

Betulinic acid derivatives that target gp120 and inhibit multiple genetic subtypes of human immunodeficiency virus type 1.

scientific article published on 22 October 2007

Bifunctional anti-human immunodeficiency virus type 1 small molecules with two novel mechanisms of action.

scientific article published on February 2004

Conformation of gp120 determines the sensitivity of HIV-1 DH012 to the entry inhibitor IC9564.

scientific article published in July 2004

Design and synthesis of naphthoquinone derivatives as antiproliferative agents and 20S proteasome inhibitors

scientific article

Design, synthesis, and preclinical evaluations of novel 4-substituted 1,5-diarylanilines as potent HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) drug candidates.

scientific article

Discovery of novel 5-fluoro-N(2),N(4)-diphenylpyrimidine-2,4-diamines as potent inhibitors against CDK2 and CDK9.

scientific article published on March 2015

Discovery of novel non-covalent inhibitors selective to the β5-subunit of the human 20S proteasome

scientific article published on 16 May 2015

Identification and synthesis of quinolizidines with anti-influenza a virus activity

scientific article

Induction of a nonproductive conformational change in gp120 by a small molecule HIV type 1 entry inhibitor

scientific article published on 01 January 2007

Inhibition of HIV-1 maturation via drug association with the viral Gag protein in immature HIV-1 particles

scientific article published on 25 October 2005

Mechanism of action and resistant profile of anti-HIV-1 coumarin derivatives.

scientific article published on February 2005

New betulinic acid derivatives for bevirimat-resistant human immunodeficiency virus type-1.

scientific article published on 20 February 2013

Optimization of 2,4-diarylanilines as non-nucleoside HIV-1 reverse transcriptase inhibitors

scientific article

Optimization of the antiviral potency and lipophilicity of halogenated 2,6-diarylpyridinamines as a novel class of HIV-1 NNRTIS.

scientific article

Phenolic diterpenoid derivatives as anti-influenza a virus agents

scientific article published on 29 January 2015

Picomolar dichotomous activity of gnidimacrin against HIV-1.

scientific article

Potential drug targets on the HIV-1 envelope glycoproteins, gp120 and gp41.

scientific article

Proteasome regulators: activators and inhibitors.

scientific article published on January 2009

Structure of a tethered cationic 3-aminopropyl chain incorporated into an oligodeoxynucleotide: evidence for 3'-orientation in the major groove accompanied by DNA bending

scientific article

Suksdorfin: an anti-HIV principle from Lomatium suksdorfii, its structure-activity correlation with related coumarins, and synergistic effects with anti-AIDS nucleosides

scientific article published on October 1994

Synthesis and anti-HIV activity of bi-functional betulinic acid derivatives

scientific article published on 28 November 2005

Synthesis and proteasome inhibition of lithocholic acid derivatives

scientific article

Synthesis of Lithocholic Acid Derivatives as Proteasome Regulators ⬇️

scientific article published on August 15, 2012

Synthesis of betulinic acid derivatives as entry inhibitors against HIV-1 and bevirimat-resistant HIV-1 variants

scientific article

List of works by Li Huang

Activation and inhibition of the proteasome by betulinic acid and its derivatives

Anti-AIDS agents 79. Design, synthesis, molecular modeling and structure-activity relationships of novel dicamphanoyl-2',2'-dimethyldihydropyranochromone (DCP) analogs as potent anti-HIV agents.

Anti-AIDS agents 81. Design, synthesis, and structure-activity relationship study of betulinic acid and moronic acid derivatives as potent HIV maturation inhibitors

Anti-AIDS agents 85. Design, synthesis, and evaluation of 1R,2R-dicamphanoyl-3,3-dimethyldihydropyrano-[2,3-c]xanthen-7(1H)-one (DCX) derivatives as novel anti-HIV agents.

Anti-AIDS agents 90. novel C-28 modified bevirimat analogues as potent HIV maturation inhibitors.

Anti-AIDS agents. 78. Design, synthesis, metabolic stability assessment, and antiviral evaluation of novel betulinic acid derivatives as potent anti-human immunodeficiency virus (HIV) agents

Betulinic acid derivatives that target gp120 and inhibit multiple genetic subtypes of human immunodeficiency virus type 1.

Bifunctional anti-human immunodeficiency virus type 1 small molecules with two novel mechanisms of action.

Conformation of gp120 determines the sensitivity of HIV-1 DH012 to the entry inhibitor IC9564.

Design and synthesis of naphthoquinone derivatives as antiproliferative agents and 20S proteasome inhibitors

Design, synthesis, and preclinical evaluations of novel 4-substituted 1,5-diarylanilines as potent HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) drug candidates.

Discovery of novel 5-fluoro-N(2),N(4)-diphenylpyrimidine-2,4-diamines as potent inhibitors against CDK2 and CDK9.

Discovery of novel non-covalent inhibitors selective to the β5-subunit of the human 20S proteasome

Identification and synthesis of quinolizidines with anti-influenza a virus activity

Induction of a nonproductive conformational change in gp120 by a small molecule HIV type 1 entry inhibitor

Inhibition of HIV-1 maturation via drug association with the viral Gag protein in immature HIV-1 particles

Mechanism of action and resistant profile of anti-HIV-1 coumarin derivatives.

New betulinic acid derivatives for bevirimat-resistant human immunodeficiency virus type-1.

Optimization of 2,4-diarylanilines as non-nucleoside HIV-1 reverse transcriptase inhibitors

Optimization of the antiviral potency and lipophilicity of halogenated 2,6-diarylpyridinamines as a novel class of HIV-1 NNRTIS.

Phenolic diterpenoid derivatives as anti-influenza a virus agents

Picomolar dichotomous activity of gnidimacrin against HIV-1.

Potential drug targets on the HIV-1 envelope glycoproteins, gp120 and gp41.

Proteasome regulators: activators and inhibitors.

Structure of a tethered cationic 3-aminopropyl chain incorporated into an oligodeoxynucleotide: evidence for 3'-orientation in the major groove accompanied by DNA bending

Suksdorfin: an anti-HIV principle from Lomatium suksdorfii, its structure-activity correlation with related coumarins, and synergistic effects with anti-AIDS nucleosides

Synthesis and anti-HIV activity of bi-functional betulinic acid derivatives

Synthesis and proteasome inhibition of lithocholic acid derivatives

Synthesis of Lithocholic Acid Derivatives as Proteasome Regulators ⬇️

Synthesis of betulinic acid derivatives as entry inhibitors against HIV-1 and bevirimat-resistant HIV-1 variants