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List of works by Kathrin Thedieck

A dynamic network model of mTOR signaling reveals TSC-independent mTORC2 regulation

scientific article

A modelling-experimental approach reveals insulin receptor substrate (IRS)-dependent regulation of adenosine monosphosphate-dependent kinase (AMPK) by insulin

scientific article

A systems study reveals concurrent activation of AMPK and mTOR by amino acids

scientific article published on 21 November 2016

Bile proteomic profiles differentiate cholangiocarcinoma from primary sclerosing cholangitis and choledocholithiasis

scientific article

CGEF-1 regulates mTORC1 signaling during adult longevity and stress response in C. elegans.

scientific article published on 6 January 2018

Differential control of ageing and lifespan by isoforms and splice variants across the mTOR network.

scientific article published on 11 July 2017

Functional Proteomics Identifies Acinus L as a Direct Insulin- and Amino Acid-Dependent Mammalian Target of Rapamycin Complex 1 (mTORC1) Substrate.

scientific article published on 23 April 2015

G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling

scientific article published on 25 January 2021

Inhibition of mTORC1 by astrin and stress granules prevents apoptosis in cancer cells

scientific article

Molecular mechanisms of mTOR regulation by stress

scientific article published on 3 December 2014

Oncogenic β-catenin and PIK3CA instruct network states and cancer phenotypes in intestinal organoids.

scientific article

PI(18:1/18:1) is a SCD1-derived lipokine that limits stress signaling

scientific article published on 27 May 2022

PI3K-p110-alpha-subtype signalling mediates survival, proliferation and neurogenesis of cortical progenitor cells via activation of mTORC2.

scientific article published on 3 May 2014

PLK1 (polo like kinase 1) inhibits MTOR complex 1 and promotes autophagy

scientific article published on 19 January 2017

PRAS40 and PRR5-like protein are new mTOR interactors that regulate apoptosis.

scientific article

Partially non-homogeneous dynamic Bayesian networks based on Bayesian regression models with partitioned design matrices

scientific article published in June 2019

Podocytes maintain high basal levels of autophagy independent of mtor signaling

scientific article published on 23 December 2019

Proteins induced by telomere dysfunction and DNA damage represent biomarkers of human aging and disease

scholarly article

T cell receptor-mediated activation is a potent inducer of macroautophagy in human CD8+CD28+ T cells but not in CD8+CD28− T cells

scientific article published on 24 January 2014

TGFβ-Signaling and FOXG1-Expression Are a Hallmark of Astrocyte Lineage Diversity in the Murine Ventral and Dorsal Forebrain

scientific article published on 28 November 2018

TSC1 activates TGF-β-Smad2/3 signaling in growth arrest and epithelial-to-mesenchymal transition

scientific article

The MprF protein is required for lysinylation of phospholipids in listerial membranes and confers resistance to cationic antimicrobial peptides (CAMPs) on Listeria monocytogenes

scientific article

The PI3K and MAPK/p38 pathways control stress granule assembly in a hierarchical manner

scientific article published on 28 March 2019

Tomatidine, a novel antiviral compound towards dengue virus

scientific article published on 22 November 2018

Tumor-Intrinsic PD-L1 Signals Regulate Cell Growth, Pathogenesis, and Autophagy in Ovarian Cancer and Melanoma.

scientific article published on 26 September 2016

Upregulation of tryptophanyl-tRNA synthethase adapts human cancer cells to nutritional stress caused by tryptophan degradation

scientific article published on 05 September 2018

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