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List of works by Barbara E. Corkey

-Cell Mitochondria Exhibit Membrane Potential Heterogeneity That Can Be Altered by Stimulatory or Toxic Fuel Levels

article

3H-serotonin as a marker of oscillatory insulin secretion in clonal β-cells (INS-1)

scientific article published on 30 July 2007

A distinct difference in the metabolic stimulus–response coupling pathways for regulating proinsulin biosynthesis and insulin secretion that lies at the level of a requirement for fatty acyl moieties ⬇️

scientific article published on April 15, 1998

A role for malonyl-CoA in glucose-stimulated insulin secretion from clonal pancreatic beta-cells

scientific article published on December 1989

Activation of the ATP-sensitive K+ channel by long chain acyl-CoA. A role in modulation of pancreatic beta-cell glucose sensitivity.

scientific article

Acute stimulation with long chain acyl-CoA enhances exocytosis in insulin-secreting cells (HIT T-15 and NMRI beta-cells).

scientific article

Aging results in paradoxical susceptibility of fat cell progenitors to lipotoxicity

scientific article published on 05 December 2006

Are the beta-cell signaling molecules malonyl-CoA and cystolic long-chain acyl-CoA implicated in multiple tissue defects of obesity and NIDDM?

scientific article published on March 1996

Beta-cell hypersensitivity to glucose following 24-h exposure of rat islets to fatty acids

scientific article published on 01 April 1997

CYTOKINES INHIBIT FATTY ACID OXIDATION IN ISOLATED RAT HEPATOCYTES

scientific article published on 01 February 1994

Cytosolic free calcium in adipocytes. Distinct mechanisms of regulation and effects on insulin action

scientific article

Diabetes: have we got it all wrong? Insulin hypersecretion and food additives: cause of obesity and diabetes?

scientific article

Dual role of proapoptotic BAD in insulin secretion and beta cell survival

scientific journal article

Effects of dietary medium-chain triglyceride on weight loss and insulin sensitivity in a group of moderately overweight free-living type 2 diabetic Chinese subjects

scientific article

Effects of medium chain triglycerides supplementation on insulin sensitivity and beta cell function: A feasibility study

scientific article published on 23 December 2019

Esterification of free fatty acids in adipocytes: a comparison between octanoate and oleate

scientific article published on July 2000

Evidence for a Unique Long Chain Acyl-CoA Ester Binding Site on the ATP-regulated Potassium Channel in Mouse Pancreatic Beta Cells

scientific article published in Journal of Biological Chemistry

Evidence for an anaplerotic/malonyl-CoA pathway in pancreatic beta-cell nutrient signaling

scientific article published in February 1996

Free fatty acid regulation of glucose-dependent intrinsic oscillatory lipolysis in perifused isolated rat adipocytes

scientific article

Glucagon-like peptide 1 and fatty acids amplify pulsatile insulin secretion from perifused rat islets

scientific article

Glucose-6-phosphate isomerase deficiency results in mTOR activation, failed translocation of lipin 1α to the nucleus and hypersensitivity to glucose: Implications for the inherited glycolytic disease

scientific article

Glucose-dependent insulin modulation of oscillatory lipolysis in perifused rat adipocytes.

scientific article published on December 2005

Glucose-dependent insulinotropic polypeptide enhances adipocyte development and glucose uptake in part through Akt activation.

scientific article published on 14 September 2007

Glucose-dependent insulinotropic polypeptide modulates adipocyte lipolysis and reesterification

scientific article

Glucose-induced activation of pyruvate dehydrogenase in isolated rat pancreatic islets

scientific article published on April 1990

Glucose-induced metabolic oscillations parallel those of Ca(2+) and insulin release in clonal insulin-secreting cells. A multiwell approach to oscillatory cell behavior

scientific article published on 31 July 2001

Glucose-induced oscillatory insulin secretion in perifused rat pancreatic islets and clonal beta-cells (HIT).

scientific article

Glucose-induced toxicity in insulin-producing pituitary cells that coexpress GLUT2 and glucokinase. Implications for metabolic engineering

scientific article published on 6 July 2001

Hormone-sensitive lipase has a role in lipid signaling for insulin secretion but is nonessential for the incretin action of glucagon-like peptide 1.

scientific article

Hyperinsulinemia: An Early Indicator of Metabolic Dysfunction

scientific article published on 24 July 2019

Hypothesis: Induction of Autoimmunity in Type 1 Diabetes—A Lipid Focus

scientific article published in 2022

Incorporation of [1-13C]oleate into cellular triglycerides in differentiating 3T3L1 cells

scientific article published on August 1999

Increased beta-oxidation in muscle cells enhances insulin-stimulated glucose metabolism and protects against fatty acid-induced insulin resistance despite intramyocellular lipid accumulation

scientific article published on 22 April 2004

Linked oscillations of free Ca2+ and the ATP/ADP ratio in permeabilized RINm5F insulinoma cells supplemented with a glycolyzing cell-free muscle extract

scientific article

Long chain coenzyme A esters activate the pore-forming subunit (Kir6. 2) of the ATP-regulated potassium channel

scientific article published in November 1998

Long-chain CoA esters activate human pancreatic beta-cell KATP channels: potential role in Type 2 diabetes

scientific article

Long-chain acyl CoA regulation of protein kinase C and fatty acid potentiation of glucose-stimulated insulin secretion in clonal beta-cells

scientific article

Long-chain fatty acids inhibit acetyl-CoA carboxylase gene expression in the pancreatic beta-cell line INS-1.

scientific article published on March 1997

Long-term exposure of beta-INS cells to high glucose concentrations increases anaplerosis, lipogenesis, and lipogenic gene expression

scientific article published on July 1998

Malonyl coenzyme A and adiposity in the dahl salt-sensitive rat: Effects of pioglitazone

scientific article published on 01 April 1996

Malonyl-CoA and long chain acyl-CoA esters as metabolic coupling factors in nutrient-induced insulin secretion ⬇️

scientific article published on March 25, 1992

Mechanism of cloned ATP-sensitive potassium channel activation by oleoyl-CoA

scientific article

Medium-chain Fatty acids attenuate agonist-stimulated lipolysis, mimicking the effects of starvation

scientific article published on April 2004

Medium-chain oil reduces fat mass and down-regulates expression of adipogenic genes in rats

scientific article published on June 2003

Metabolic master regulators: sharing information among multiple systems.

scientific article

Metabolic partitioning of endogenous fatty acid in adipocytes

scientific article

Mitochondrial metabolism reveals a functional architecture in intact islets of Langerhans from normal and diabetic Psammomys obesus

scientific article published on 31 August 2004

Mitochondrial networking protects beta-cells from nutrient-induced apoptosis.

scientific article published on 06 July 2009

Negative regulation of ligand-initiated Ca(2+) uptake by PKC-beta II in differentiated HL60 cells

scientific article published in August 2001

New scanning electron microscopic method for determination of adipocyte size in humans and mice

scientific article published in July 2007

Octanoate attenuates adipogenesis in 3T3-L1 preadipocytes

scientific article published on May 2002

Octanoate inhibits triglyceride synthesis in 3T3-L1 and human adipocytes

scientific article published on August 2003

Oleate-induced formation of fat cells with impaired insulin sensitivity

scientific article

Oscillations in oxygen consumption by permeabilized clonal pancreatic beta-cells (HIT) incubated in an oscillatory glycolyzing muscle extract: roles of free Ca2+, substrates, and the ATP/ADP ratio.

scientific article published on January 1997

Persistent oxidative stress due to absence of uncoupling protein 2 associated with impaired pancreatic beta-cell function

scientific article

Phosphofructokinase isozymes in pancreatic islets and clonal beta-cells (INS-1).

scientific article published on November 1995

Potentiation of insulin secretion by phorbol esters is mediated by PKC-alpha and nPKC isoforms

scientific article published in November 2002

ROS signaling, oxidative stress and Nrf2 in pancreatic beta-cell function

scientific article

Rab3A effector domain peptides induce insulin exocytosis via a specific interaction with a cytosolic protein doublet.

scientific article published on November 1994

Rapid Flip-flop of Oleic Acid across the Plasma Membrane of Adipocytes

scientific article published in Journal of Biological Chemistry

Reactive oxygen species as a signal in glucose-stimulated insulin secretion

scientific article

Reactive oxygen species stimulate insulin secretion in rat pancreatic islets: studies using mono-oleoyl-glycerol

scientific article

Reactive oxygen species: role in obesity and mitochondrial energy efficiency

scientific article published in 2023

Regulation of acetyl CoA carboxylase and carnitine palmitoyl transferase-1 in rat adipocytes

scientific article

Regulation of lipolytic activity by long-chain acyl-coenzyme A in islets and adipocytes

scientific article published on 9 August 2005

Regulation of pancreatic beta-cell mitochondrial metabolism: influence of Ca2+, substrate and ADP.

scientific article published on September 1996

Regulation of steady-state free Ca2+ levels by the ATP/ADP ratio and orthophosphate in permeabilized RINm5F insulinoma cells

scientific article

Relationship between unusual hepatic acyl coenzyme A profiles and the pathogenesis of Reye syndrome.

scientific article

Reversible Ca2+-dependent translocation of protein kinase C and glucose-induced insulin release.

scientific article published on July 1996

Selective activation of Ca2+ influx by extracellular ATP in a pancreatic β-cell line (HIT)

scientific article published on 01 June 1989

Signal transduction mechanisms in nutrient-induced insulin secretion

scientific article published on July 1997

Single residue (K332A) substitution in Kir6.2 abolishes the stimulatory effect of long-chain acyl-CoA esters: indications for a long-chain acyl-CoA ester binding motif

scientific article

Succinate is a preferential metabolic stimulus-coupling signal for glucose-induced proinsulin biosynthesis translation

scientific article published in August 2002

Sulfonylureas rapidly cross phospholipid bilayer membranes by a free-diffusion mechanism

scientific article published in October 2003

Synaptotagmin III isoform is compartmentalized in pancreatic beta-cells and has a functional role in exocytosis

scientific article published on March 2000

Temporal patterns of changes in ATP/ADP ratio, glucose 6-phosphate and cytoplasmic free Ca2+ in glucose-stimulated pancreatic beta-cells

scientific article published on February 1996

Temporal profiling of the secretome during adipogenesis in humans

scientific article

Temporal sequence of metabolic and ionic events in glucose-stimulated clonal pancreatic beta-cells (HIT).

scientific article published on May 1996

The CB1 antagonist rimonabant decreases insulin hypersecretion in rat pancreatic islets

scientific journal article

Two sites for adenine-nucleotide regulation of ATP-sensitive potassium channels in mouse pancreatic ?-cells and HIT cells

scientific article published on 01 September 1992

Type 1 diabetes alters lipid handling and metabolism in human fibroblasts and peripheral blood mononuclear cells

scientific article published on 4 December 2017

β3-Adrenergic Receptors on White and Brown Adipocytes Mediate β3-Selective Agonist-induced Effects on Energy Expenditure, Insulin Secretion, and Food Intake

scientific article published in Journal of Biological Chemistry

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