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List of works by Thomas Weichhart

A New Immunomodulatory Role for Peroxisomes in Macrophages Activated by the TLR4 Ligand Lipopolysaccharide

scientific article

A kinase-independent role for CDK8 in BCR-ABL1+ leukemia

scientific article published on 18 October 2019

A randomized, placebo-controlled, double-blind, prospective trial to evaluate the effect of vildagliptin in new-onset diabetes mellitus after kidney transplantation

scientific article published on 6 October 2010

A versatile role of mammalian target of rapamycin in human dendritic cell function and differentiation

scientific article published on 30 August 2010

Antithymocyte globulin impairs T-cell/antigen-presenting cell interaction: disruption of immunological synapse and conjugate formation.

scientific article

Apoptotic cell-free DNA promotes inflammation in haemodialysis patients

scientific article published on 13 December 2011

Applied immuno-epidemiological research: an approach for integrating existing knowledge into the statistical analysis of multiple immune markers

scientific article

Biological action of rapamycin in renal transplantation.

scientific article

Blood volume-monitored regulation of ultrafiltration in fluid-overloaded hemodialysis patients: study protocol for a randomized controlled trial.

scientific article

CMV late phase-induced mTOR activation is essential for efficient virus replication in polarized human macrophages.

scientific article published on 5 March 2012

Chronic signaling via the metabolic checkpoint kinase mTORC1 induces macrophage granuloma formation and marks sarcoidosis progression

scientific article published on 16 January 2017

Current Insights in Genetics of Sarcoidosis: Functional and Clinical Impacts

scientific article published on 13 August 2020

Current concepts of molecular defence mechanisms operative during urinary tract infection

scientific article published on October 2008

Drug-induced pneumonitis in cancer patients treated with mTOR inhibitors: management and insights into possible mechanisms.

scientific article published on 11 February 2014

Effect of the proteasome inhibitor bortezomib on humoral immunity in two presensitized renal transplant candidates

scientific article published in June 2010

Effects of Interferons and Viruses on Metabolism

scientific article

Effects of the mTOR inhibitor everolimus and the PI3K/mTOR inhibitor NVP-BEZ235 in murine acute lung injury models.

scientific article

Environmental arginine controls multinuclear giant cell metabolism and formation

scientific article published on 22 January 2020

Exome sequencing and pathogenicity-network analysis of five French families implicate mTOR signalling and autophagy in familial sarcoidosis

scientific article published on 01 August 2019

Functional selection of vaccine candidate peptides from Staphylococcus aureus whole-genome expression libraries in vitro

scientific article

HDL Cholesterol Efflux Does Not Predict Cardiovascular Risk in Hemodialysis Patients

scientific article published on 9 September 2016

Hereditary amyloidosis caused by R554L fibrinogen Aα-chain mutation in a Spanish family and review of the literature.

scientific article published on 03 April 2013

Identification of the scavenger receptors SREC-I, Cla-1 (SR-BI), and SR-AI as cellular receptors for Tamm-Horsfall protein.

scientific article

Immune responses of macrophages and dendritic cells regulated by mTOR signalling.

scientific article published on August 2013

Impairment of T cell interactions with antigen-presenting cells by immunosuppressive drugs reveals involvement of calcineurin and NF-κB in immunological synapse formation

article

Inactivation of mTORC2 in macrophages is a signature of colorectal cancer that promotes tumorigenesis

scientific article published on 17 October 2019

Inhibition of mTOR blocks the anti-inflammatory effects of glucocorticoids in myeloid immune cells.

scientific article published on 2 March 2011

Inhibition of mTOR down-regulates scavenger receptor, class B, type I (SR-BI) expression, reduces endothelial cell migration and impairs nitric oxide production.

scientific article

Inverse Data-Driven Modeling and Multiomics Analysis Reveals Phgdh as a Metabolic Checkpoint of Macrophage Polarization and Proliferation

scientific article published on 01 February 2020

Iron Regulation: Macrophages in Control

scholarly article by Nyamdelger Sukhbaatar & Thomas Weichhart published 14 December 2018 in Pharmaceuticals

Late onset Pneumocystis pneumonia in renal transplantation after long-term immunosuppression with belatacept.

scientific article published on 5 February 2009

Lysis gradient centrifugation: a flexible method for the isolation of nuclei from primary cells

scientific article published on 01 January 2015

Mammalian Target of Rapamycin: A Signaling Kinase for Every Aspect of Cellular Life ⬇️

scientific article published on January 1, 2012

Metabolic Programming of Macrophages: Implications in the Pathogenesis of Granulomatous Disease

scientific article published on 04 October 2019

Neutralization of osteopontin inhibits obesity-induced inflammation and insulin resistance.

scientific article

Osteopontin expression in human and murine obesity: extensive local up-regulation in adipose tissue but minimal systemic alterations.

scientific article published on 29 November 2007

PDGFR blockade is a rational and effective therapy for NPM-ALK-driven lymphomas

scientific article

Prevention of high-fat diet-induced adipose tissue remodeling in obese diabetic mice by n-3 polyunsaturated fatty acids.

scientific article published on 28 November 2006

Pro- versus Anti-inflammatory Actions of HDLs in Innate Immunity

scientific article published on 8 June 2017

Quantification of HDL proteins, cardiac events, and mortality in patients with type 2 diabetes on hemodialysis.

scientific article

Rapid isolation of nuclei from living immune cells by a single centrifugation through a multifunctional lysis gradient

scientific article

Regulation of innate immune cell function by mTOR.

scientific article published on September 2015

Restoration of renal function does not correct impairment of uremic HDL properties

scientific article

Serum amyloid A in uremic HDL promotes inflammation

scientific article published on 26 January 2012

Sirolimus and kidney transplantation: unraveling an inflammatory affair

scientific article published on December 2010

Sirolimus in renal transplant recipients with tuberous sclerosis complex: clinical effectiveness and implications for innate immunity.

scientific article published on 11 January 2010

T helper cell differentiation: understanding the needs of hierarchy

scientific article published on June 2010

TORching a semaphore for alternative macrophage activation

scientific article published on 01 June 2018

Tamm-Horsfall glycoprotein links innate immune cell activation with adaptive immunity via a Toll-like receptor-4-dependent mechanism.

scientific article

Targeting the dysregulated mammalian target of rapamycin pathway in organ transplantation: killing 2 birds with 1 stone ⬇️

scientific article published on March 17, 2011

The PI3K pathway preserves metabolic health through MARCO-dependent lipid uptake by adipose tissue macrophages

scientific article published on 16 November 2020

The TSC-mTOR signaling pathway regulates the innate inflammatory response

scientific article

The anti-inflammatory potency of dexamethasone is determined by the route of application in vivo

scientific article published on 12 January 2010

The multifunctional role of mTOR in innate immunity: implications for transplant immunity.

scientific article published on 25 September 2009

The multiple facets of mTOR in immunity.

scientific article published on 08 April 2009

The multiple functions of Tamm-Horsfall protein in human health and disease: a mystery clears up.

scientific article

The versatility of HDL: a crucial anti-inflammatory regulator.

scientific article published on December 2010

Toll-like receptors and chondrocytes: the lipopolysaccharide-induced decrease in cartilage matrix synthesis is dependent on the presence of toll-like receptor 4 and antagonized by bone morphogenetic protein 7

scientific article published on 01 June 2007

Uncovering host defences in the urinary tract: cathelicidin and beyond.

scientific article published on 11 October 2006

Whole exome sequencing in three families segregating a pediatric case of sarcoidosis

scientific article published on 6 March 2018

[Causes of recurrent urinary tract infections: new insights]

scientific article published on 01 September 2005

mTOR Senses Environmental Cues to Shape the Fibroblast-like Synoviocyte Response to Inflammation.

scientific article published in May 2018

mTOR as Regulator of Lifespan, Aging, and Cellular Senescence: A Mini-Review

scientific article published in December 2017

mTOR-Mediated Regulation of Dendritic Cell Differentiation and Function

scientific article published on 7 September 2016

mTORC1 and mTORC2 as regulators of cell metabolism in immunity.

scientific article

mTORC1 is essential for early steps during Schwann cell differentiation of amniotic fluid stem cells and regulates lipogenic gene expression

scientific article

p38α senses environmental stress to control innate immune responses via mechanistic target of rapamycin

scientific article published on 11 January 2013

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