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List of works by Naoki Kanoh

A concise and unified strategy for synthesis of the C1-C18 macrolactone fragments of FD-891, FD-892 and their analogues: formal total synthesis of FD-891.

scientific article published on 23 September 2014

A mild two-step propargylation of aromatic bioactive small molecules

scientific article published on 16 August 2017

An expedient route to a potent gastrin/CCK-B receptor antagonist (+)-AG-041R

scientific article published on 01 October 2009

An improved fluorogenic NAD(P)+ detection method using 2-acetylbenzofuran: its origin and application

scientific article published on 01 December 2013

An integrated screening system for the selection of exemplary substrates for natural and engineered cytochrome P450s

scientific article published on 02 December 2019

Asymmetric Total Synthesis of Heronamides A-C: Stereochemical Confirmation and Impact of Long-Range Stereochemical Communication on the Biological Activity

scientific article published on 12 May 2016

Cleavable linker for photo-cross-linked small-molecule affinity matrix

scientific article published on 01 January 2010

Concise entry to both enantiomers of 8-oxabicyclo[3.2.1]oct-3-en-2-one based on novel oxidative etherification: formal synthesis of (+)-sundiversifolide

scientific article published on 09 June 2011

Concise, Protecting-Group-Free Synthesis of (+)-Nemonapride via Eu(OTf)3-Catalyzed Aminolysis of 3,4-Epoxy Alcohol.

scientific article

Design and synthesis of the penta(acetoxymethyl) ester of dioctanoyl phosphatidylinositol-3,5-bisphosphate.

scientific article published on 15 October 2016

Detection of cytochrome P450 substrates by using a small-molecule droplet array on an NADH-immobilized solid surface

scientific article published on 07 November 2011

Dual structure-activity relationship of osteoclastogenesis inhibitor methyl gerfelin based on TEG scanning.

scientific article

Eu(OTf)3-catalyzed highly regioselective nucleophilic ring opening of 2,3-epoxy alcohols: an efficient entry to 3-substituted 1,2-diol derivatives

scientific article published on 27 August 2014

Gold(i)-catalyzed Nicholas reaction with aromatic molecules utilizing a bifunctional propargyl dicobalt hexacarbonyl complex

scientific article published on 01 September 2019

Highly Chemoselective gem-Difluoropropargylation of Aliphatic Alcohols

scientific article published on 18 October 2019

Highly enantioselective intramolecular aza-spiroannulation onto indoles using chiral rhodium catalysis: asymmetric entry to the spiro-beta-lactam core of chartellines

scientific article published on 02 September 2009

Immobilization of natural products on glass slides by using a photoaffinity reaction and the detection of protein-small-molecule interactions

scientific article published in November 2003

Irciniastatin A induces JNK activation that is involved in caspase-8-dependent apoptosis via the mitochondrial pathway.

scientific article published on December 2010

Irciniastatin A, a pederin-type translation inhibitor, promotes ectodomain shedding of cell-surface tumor necrosis factor receptor 1.

scientific article

KSRP/FUBP2 Is a Binding Protein of GO-Y086, a Cytotoxic Curcumin Analogue

scientific article published on 4 June 2010

Nazarov Cyclization Entry to Chiral Bicyclo[5.3.0]decanoid Building Blocks and Its Application to Formal Synthesis of (-)-Englerin A

scientific article published on 27 September 2017

Phoslactomycin targets cysteine-269 of the protein phosphatase 2A catalytic subunit in cells

scientific article

Photo-cross-linked small-molecule affinity matrix as a tool for target identification of bioactive small molecules.

scientific article published on 24 February 2016

Photo-cross-linked small-molecule affinity matrix for facilitating forward and reverse chemical genetics

scientific article published in June 2005

Photo-cross-linked small-molecule microarrays as chemical genomic tools for dissecting protein-ligand interactions.

scientific article published in December 2006

Preparation of photo-cross-linked small molecule affinity matrices for affinity selection of protein targets for biologically active small molecules.

scientific article

Reversibility of the thia-Michael reaction of cytotoxic C5-curcuminoid and structure-activity relationship of bis-thiol-adducts thereof

scientific article published on 01 November 2016

SPR imaging of photo-cross-linked small-molecule arrays on gold.

scientific article

Stereocontrolled Construction of ABCD Tetracyclic Ring System with Vicinal All-Carbon Quaternary Stereogenic Centers of Calyciphylline A Type Alkaloids

scientific article published on 07 May 2018

Structure-Activity Relationships of the Antitumor C5-Curcuminoid GO-Y030

scientific article published on 24 August 2015

Structure-activity relationship of C5-curcuminoids and synthesis of their molecular probes thereof

scientific article

Structure-affinity relationship study of bleomycins and Shble protein by use of a chemical array

scientific article published in March 2009

Structure-function analyses of cytochrome P450revI involved in reveromycin A biosynthesis and evaluation of the biological activity of its substrate, reveromycin T.

scientific article published on 25 September 2014

Studies aimed at the total synthesis of azadirachtin. A modeled connection of C-8 and C-14 in azadirachtin

scientific article published in August 2002

Substrate Recognition by a Dual-Function P450 Monooxygenase GfsF Involved in FD-891 Biosynthesis.

scientific article published on 4 September 2017

Syntheses and biological evaluation of irciniastatin A and the C1-C2 alkyne analogue

scientific article published on 01 March 2010

Syntheses of naturally occurring cytotoxic [7.7]paracyclophanes, (-)-cylindrocyclophane A and its enantiomer, and implications for biological activity

scientific article published on 14 July 2009

Synthesis and biological activities of reveromycin A and spirofungin A derivatives.

scientific article published on 17 May 2008

Synthesis and structure-activity relationship of vicenistatin, a cytotoxic 20-membered macrolactam glycoside

scientific article

Synthesis and structure-activity relationship study of FD-891: importance of the side chain and C8-C9 epoxide for cytotoxic activity against cancer cells

scientific article published on 27 January 2016

Synthetic Access to <i>gem</i>-Difluoropropargyl Vinyl Ethers and Their Application to Propargyl Claisen Rearrangement

scientific article published on 07 December 2020

Synthetic studies on daphnicyclidin A: enantiocontrolled construction of the BCD ring system

scientific article published on 01 April 2009

The anticancer natural product pironetin selectively targets Lys352 of alpha-tubulin.

scientific article published on June 2004

Third generation photo-cross-linked small-molecule affinity matrix: a photoactivatable and photocleavable system enabling quantitative analysis of the photo-cross-linked small molecules and their target purification

scientific article published on 18 February 2015

Total Synthesis and Biological Evaluation of Irciniastatin A (a.k.a. Psymberin) and Irciniastatin B.

scientific article published on 6 November 2015

Total synthesis and determination of the absolute configuration of (-)-idesolide.

scientific article published in March 2010

Total synthesis of methyl sarcophytoate

scientific article published on 21 July 2007

Total synthesis of methyl sarcophytoate, a marine natural biscembranoid

scientific article published on 01 January 2009

Tremorgenic indole alkaloids. The total synthesis of (-)-penitrem D.

scientific article

Vicenistatin induces early endosome-derived vacuole formation in mammalian cells

scientific article published on February 2016

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