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List of works by Valerio De Stefano

A Novel Morphological Parameter Predicting Fibrotic Evolution in Myeloproliferative Neoplasms: New Evidence and Molecular Insights

scientific article published in 2022

A multistate model of survival prediction and event monitoring in prefibrotic myelofibrosis

scientific article published on 14 October 2020

Abdominal thromboses of splanchnic, renal and ovarian veins.

scientific article published on 11 August 2012

Absence of the JAK2 exon 12 mutations in patients with splanchnic venous thrombosis and without overt myeloproliferative neoplasms

scientific article published on 01 February 2009

Acquired and inherited risk factors for splanchnic venous thrombosis

scientific article published on 01 May 2001

Additional genetic risk factors for venous thromboembolism in carriers of the factor V Leiden mutation.

scientific article published in December 1998

Addressing and proposing solutions for unmet clinical needs in the management of myeloproliferative neoplasm-associated thrombosis: A consensus-based position paper

scientific article published on 08 August 2019

Alpha(2)-macroglobulin levels are high in adult patients with congenital antithrombin deficiency

scientific article published in April 2000

Alternate use of thrombopoietin receptor agonists in adult primary immune thrombocytopenia patients: A retrospective collaborative survey from Italian hematology centers.

scientific article published on 6 October 2017

Anticoagulation for the treatment of portal vein thrombosis in liver cirrhosis: a systematic review and meta-analysis of observational studies

scientific article published on 5 January 2015

Antithrombin III and factor Xa inhibitor in atherosclerosis

scientific article published on 01 January 1983

Antithrombotic prophylaxis during pregnancy in women with deficiency of natural anticoagulants.

scientific article published in April 2008

Are MPNs vascular diseases?

scientific article published on December 2013

Arterial and venous thrombosis in patients with monoclonal gammopathy of undetermined significance: incidence and risk factors in a cohort of 1491 patients

scientific article published on 13 December 2012

Arterial thrombosis in Philadelphia-negative myeloproliferative neoplasms predicts second cancer: a case-control study

scientific article published on 01 January 2020

Association of Graves' disease and prekallikrein congenital deficiency in a patient belonging to the first CRM+ prekallikrein-deficient Italian family

scientific article published in December 1990

Associations of antiphospholipid antibodies with splanchnic vein thrombosis: a systematic review with meta-analysis

scientific article

Associations of coagulation factor V Leiden and prothrombin G20210A mutations with Budd-Chiari syndrome and portal vein thrombosis: a systematic review and meta-analysis

scientific article

Autoimmune hemolytic anemia with gel-based immunohematology tests: neural network analysis

scientific article published in January 2014

Bisphosphonate therapy in multiple myeloma in preventing vertebral collapses: preliminary report.

scientific article published on 21 March 2012

Bortezomib-thalidomide-dexamethasone is superior to thalidomide-dexamethasone as consolidation therapy after autologous hematopoietic stem cell transplantation in patients with newly diagnosed multiple myeloma

scientific article published on 12 April 2012

COVID-19 in Philadelphia-negative myeloproliferative disorders: a GIMEMA survey

scientific article published on 25 August 2020

Cardiovascular Events and Intensity of Treatment in Polycythemia Vera

scientific article published on December 8, 2012

Causes of adult splanchnic vein thrombosis in the mediterranean area.

scientific article published on 19 December 2011

Cerebral sinus-venous thrombosis

scientific article published on October 1, 2012

Cerebral vein thrombosis in patients with Philadelphia-negative myeloproliferative neoplasms. An European Leukemia Net study

scientific article published on 31 July 2014

Cerebral venous thrombosis and myeloproliferative neoplasms: Results from two large databases

scientific article published on 29 March 2014

Cerebral venous thrombosis and the risk of pregnancy-related recurrent venous thromboembolism

scientific article published on 08 June 2010

Clinical profile of homozygous JAK2 617V>F mutation in patients with polycythemia vera or essential thrombocythemia

scientific article published on 22 March 2007

Clonal hemopoiesis and risk of thrombosis in young female patients with essential thrombocythemia.

scientific article published in June 2001

Clonal populations of hematopoietic cells with paroxysmal nocturnal hemoglobinuria phenotype in patients with splanchnic vein thrombosis.

scientific article published on April 2014

Development and validation of an International Prognostic Score of thrombosis in World Health Organization-essential thrombocythemia (IPSET-thrombosis).

scientific article published on October 2012

Dexamethasone plus rituximab yields higher sustained response rates than dexamethasone monotherapy in adults with primary immune thrombocytopenia

scientific article

Different effect of hydroxyurea and phlebotomy on prevention of arterial and venous thrombosis in Polycythemia Vera

scientific article published on 26 November 2018

Early postoperative obstructive prosthetic mitral valve thrombosis in a patient double heterozygous for factor V Leiden and prothrombin G20210A mutation

scientific article published on 01 February 2008

Effect of prothrombin 19911 A>G polymorphism on the risk of cerebral sinus-venous thrombosis

scientific article published in December 2010

Efficacy and safety of ruxolitinib and hydroxyurea combination in patients with hyperproliferative myelofibrosis

scientific article published on 14 June 2019

Efficacy of lenalidomide plus dexamethasone for POEMS syndrome relapsed after autologous peripheral stem-cell transplantation.

scientific article published on 10 April 2012

Evaluation of the prevalence of severe hyperhomocysteinemia in adult patients with thrombosis who underwent screening for thrombophilia.

scientific article published on 16 October 2013

Extra-abdominal venous thromboses at unusual sites.

scientific article published on 11 August 2012

Failure of fibrinolytic endoventricular treatment to prevent neonatal post-haemorrhagic hydrocephalus. A case-control trial

scientific article published on 01 February 1997

Five novel point mutations: two causing haemophilia B and three causing factor X deficiency

scientific article published in February 1994

Fondaparinux in pregnancy: Could it be a safe option? A review of the literature

scientific article

Full Donor Chimerism After Allogeneic Hematopoietic Stem Cells Transplant For Myelofibrosis: The Role Of The Conditioning Regimen

scientific article published on 04 November 2020

Gender effect on phenotype and genotype in patients with post-polycythemia vera and post-essential thrombocythemia myelofibrosis: results from the MYSEC project

scientific article published on 21 September 2018

Haemoglobin levels in autoimmune haemolytic anaemias at diagnosis: relationship with immunoproteins on red blood cells

scientific article published in October 2014

Haemostatic alterations induced by treatment with asparaginases and clinical consequences

scientific article published on 23 October 2014

Hepatocarcinoma in cirrhosis. Is antithrombin III a neoplastic marker?

scientific article published on 01 July 1991

High mortality rate in COVID-19 patients with myeloproliferative neoplasms after abrupt withdrawal of ruxolitinib

scientific article published on 07 January 2021

High prevalence of the JAK2 V617F mutation in patients with extrahepatic portal vein thrombosis

scientific article published on 01 March 2007

How the coronavirus pandemic has affected the clinical management of Philadelphia-negative chronic myeloproliferative neoplasms in Italy-a GIMEMA MPN WP survey

scientific article published on 03 July 2020

Hydroxyurea prevents arterial and late venous thrombotic recurrences in patients with myeloproliferative neoplasms but fails in the splanchnic venous district. Pooled analysis of 1500 cases

scientific article published on 12 November 2018

Hydroxyurea-related toxicity in 3,411 patients with Ph'-negative MPN.

scientific article published on 4 April 2012

Identifying and addressing unmet clinical needs in Ph-neg classical myeloproliferative neoplasms: a consensus-based SIE, SIES, GITMO position paper

scientific article published on 19 September 2013

IgD multiple myeloma a descriptive report of 17 cases: survival and response to therapy

scientific article

Impact of JAK2(V617F) mutation status on treatment response to anagrelide in essential thrombocythemia: an observational, hypothesis-generating study

scientific article published on 18 May 2015

Impact of bone marrow fibrosis grade in post-polycythemia vera and post-essential thrombocythemia myelofibrosis: A study of the MYSEC group

scientific article published on 01 November 2019

Impact of radiotherapy on pain relief and recalcification in plasma cell neoplasms: long-term experience.

scientific article

In families with inherited thrombophilia the risk of venous thromboembolism is dependent on the clinical phenotype of the proband

scientific article published on 11 August 2011

In vitro effect of eltrombopag alone and in combination with azacitidine on megakaryopoiesis in patients with myelodysplastic syndrome

scientific article published on 08 April 2020

Incidence of the JAK2 V617F mutation among patients with splanchnic or cerebral venous thrombosis and without overt chronic myeloproliferative disorders

scientific article published on 29 January 2007

Increased prevalence of the G20210A prothrombin gene variant in acute coronary syndromes without metabolic or acquired risk factors or with limited extent of disease.

scientific article

Indications and use of therapeutic phlebotomy in polycythemia vera: which role for erythrocytapheresis?

scientific article published on 05 December 2018

Influence of proband's characteristics on the risk for venous thromboembolism in relatives with factor V Leiden or prothrombin G20210A polymorphisms.

scientific article published on 2 August 2013

Influence of the JAK2 V617F mutation and inherited thrombophilia on the thrombotic risk among patients with essential thrombocythemia.

scientific article published on 31 March 2009

Inherited risk factors for venous thromboembolism

scientific article published on 14 January 2014

Inherited thrombophilia: treatment during pregnancy

scientific article published on 01 January 2006

Italian survey on clinical practice in myeloproliferative neoplasms. A GIMEMA Myeloproliferative Neoplasms Working Party initiative

scientific article published on 22 June 2019

JAK2 V617F mutational frequency in essential thrombocythemia associated with splanchnic or cerebral vein thrombosis

scientific article published on 01 June 2011

Leukocytosis as a major thrombotic risk factor in patients with polycythemia vera

scientific article (publication date: 15 March 2007)

Long-term Clinical Outcomes of Splanchnic Vein Thrombosis: Results of an International Registry.

scientific article published on 13 July 2015

Melphalan 200 mg/m(2) versus melphalan 100 mg/m(2) in newly diagnosed myeloma patients: a prospective, multicenter phase 3 study

scientific article

Mesenteric vein thrombosis in protein S congenital deficiency

scientific article published on 01 March 1990

Methylenetetrahydrofolate reductase C677T gene mutation and hyperhomocysteinemia in Budd-Chiari syndrome and portal vein thrombosis: A systematic review and meta-analysis of observational studies.

scientific article

Molecular and clinical follow-up after stem cell transplantation for multiple myeloma

scientific article published on 01 February 2001

Mutations of epigenetic regulators and of the spliceosome machinery in therapy-related myeloid neoplasms and in acute leukemias evolved from chronic myeloproliferative diseases.

scientific article

Myeloid sarcoma with megakaryoblastic differentiation mimicking a sellar tumor.

scientific article

Natural history and risk factors for thrombosis in 360 patients with antiphospholipid antibodies: a four-year prospective study from the Italian Registry

scientific article published on 01 May 1996

Novel antithrombotic agents: indirect synthetic inhibitors of factor Xa and direct thrombin inhibitors. Evidences from clinical studies.

scientific article published in October 2004

Obstetric complications and pregnancy-related venous thromboembolism: The effect of low-molecular-weight heparin on their prevention in carriers of factor V Leiden or prothrombin G20210A mutation

scientific article published on 25 January 2012

Oral melphalan and prednisone chemotherapy plus thalidomide compared with melphalan and prednisone alone in elderly patients with multiple myeloma: randomised controlled trial

scientific article published in March 2006

Overexpression of the polycythemia rubra vera-1 gene in essential thrombocythemia

scientific article (publication date: 15 October 2002)

Philadelphia-Negative Chronic Myeloproliferative Neoplasms during the COVID-19 Pandemic: Challenges and Future Scenarios

scientific article published in 2021

Platelet activation and inhibition in polycythemia vera and essential thrombocythemia

scientific article published on 18 January 2013

Postsurgery outcomes in patients with polycythemia vera and essential thrombocythemia: a retrospective survey

scientific article published in October 2007

Prevalence of factor V Leiden and the G20210A prothrombin-gene mutation in inflammatory bowel disease.

scientific article published on July 2000

Prevalence of inherited antithrombin, protein C, and protein S deficiencies in portal vein system thrombosis and Budd-Chiari syndrome: a systematic review and meta-analysis of observational studies.

scientific article

Prevalence of mild hyperhomocysteinaemia and association with thrombophilic genotypes (factor V Leiden and prothrombin G20210A) in Italian patients with venous thromboembolic disease

scientific article published on 01 August 1999

Prevalence of the JAK2 V617F mutation in patients with unprovoked venous thromboembolism of common sites and without overt myeloproliferative neoplasms.

scientific article

Prognostic factors associated with progression of smoldering multiple myeloma to symptomatic form

scientific article published on 11 July 2012

Prophylaxis and treatment of venous thromboembolism in individuals with inherited thrombophilia.

scientific article published on November 2006

Protein Z g-42a variant and the risk of pregnancy-related venous thromboembolism in a cohort of Italian patients

scientific article published on 30 January 2009

Rare thromboses of cerebral, splanchnic and upper-extremity veins

scientific article published on 29 March 2010

Recombinant plasminogen activator therapy for cerebral vein thrombosis in a child carrier of prothrombin gene mutation

scientific article published in December 2002

Recommendations for prophylaxis of pregnancy-related venous thromboembolism in carriers of inherited thrombophilia. Comment on the 2012 ACCP guidelines

scientific article published on 01 September 2013

Recurrent thrombosis in patients with polycythemia vera and essential thrombocythemia: incidence, risk factors, and effect of treatments

scientific article published on 11 February 2008

Reply to: Second primary malignancies in myeloproliferative neoplasms and the role of aspirin

scientific article published on 07 November 2019

Reply: Interaction between inherited thrombophilia and HIV infection: fact or fancy?

scientific article published on 8 April 2014

Report of a novel kindred with antithrombin heparin-binding site variant (47 Arg to His): demand for an automated progressive antithrombin assay to detect molecular variants with low thrombotic risk

scientific article published on 01 September 2007

Risk factor and etiology analysis of ischemic stroke in young adult patients

scientific article published on 11 January 2014

Risk of venous thromboembolism associated with single and combined effects of Factor V Leiden, Prothrombin 20210A and Methylenetethraydrofolate reductase C677T: a meta-analysis involving over 11,000 cases and 21,000 controls

scientific article published on 31 July 2013

Role of flow-cytometric immunophenotyping in prediction of BCR/ABL1 gene rearrangement in adult B-cell acute lymphoblastic leukemia.

scientific article

Safety of granulocyte-colony-stimulating factor in acute myocardial infarction (the Rigenera study).

scientific article published on December 2006

Screening for thrombophilia and antithrombotic prophylaxis in pregnancy: Guidelines of the Italian Society for Haemostasis and Thrombosis (SISET).

scientific article published on 11 August 2009

Second cancer in Philadelphia negative myeloproliferative neoplasms (MPN-K). A nested case-control study

scientific article published on 29 May 2019

Second cancers in MPN: Survival analysis from an international study

scientific article published on 22 December 2019

Splanchnic vein thromboses associated with myeloproliferative neoplasms: An international, retrospective study on 518 cases

scientific article published on 29 November 2019

Splanchnic vein thrombosis: clinical presentation, risk factors and treatment.

scientific article published on 08 June 2010

Structural analysis of protein Z gene variants in patients with foetal losses

article

Targeting myeloid cells to prevent recurrent stroke in general population: the lesson of hydroxyurea in myeloproliferative neoplasms

scientific article published on 07 November 2018

Testing for inherited thrombophilia and consequences for antithrombotic prophylaxis in patients with venous thromboembolism and their relatives. A review of the Guidelines from Scientific Societies and Working Groups

scientific article published on 11 July 2013

The C807T/G873A polymorphism in the platelet glycoprotein Ia gene and the risk of acute coronary syndrome in the Italian population

scientific article published on 01 July 2001

The G20210A prothrombin variant and the risk of venous thromboembolism or fetal loss in pregnant women: a family study.

scientific article

The JAK2 V617F mutation in patients with cerebral venous thrombosis: a rebuttal

scientific article published on 01 June 2008

The Risk of Recurrent Deep Venous Thrombosis among Heterozygous Carriers of Both Factor V Leiden and the G20210A Prothrombin Mutation

scientific article published on 01 September 1999

The interaction between small intestinal bacterial overgrowth and warfarin treatment

scientific article published in September 2009

The prognostic impact of monoclonal immune globulin and free light chain secretion in diffuse large B cell lymphoma (DLBCL)

scientific article published on 31 December 2019

The risk of first venous thromboembolism during pregnancy and puerperium in double heterozygotes for factor V Leiden and prothrombin G20210A.

scientific article published on 19 December 2007

The risk of recurrent venous thromboembolism among heterozygous carriers of the G20210A prothrombin gene mutation

article

The risk of symptomatic pulmonary embolism due to proximal deep venous thrombosis differs in patients with different types of inherited thrombophilia

scientific article published on 01 June 2008

The risk of thrombosis in patients with acute leukemia: occurrence of thrombosis at diagnosis and during treatment

scientific article published on 01 September 2005

The risk of venous thromboembolism in family members with mutations in the genes of factor V or prothrombin or both

scientific article published in December 2000

Thrombopoietin receptor agonists significantly increase the risk of portal vein thrombosis in liver diseases: Meta-analysis of RCTs

scientific article published on 12 March 2015

Thrombotic risk in patients with primary immune thrombocytopenia is only mildly increased and explained by personal and treatment-related risk factors.

scientific article

Validation of the IPSET score for thrombosis in patients with prefibrotic myelofibrosis

scientific article published on 25 February 2020

Venous thromboembolism in multiple myeloma

scientific article

Venous thromboembolism in patients with liver diseases

scientific article published on 13 March 2015

Vitamin D deficiency and supplementation in patients with aggressive B-cell lymphomas treated with immunochemotherapy.

scientific article published on 22 December 2017