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Authors whose works are in public domain in at least one jurisdiction

List of works by Helen J Knowles

Acute hypoxia and osteoclast activity: a balance between enhanced resorption and increased apoptosis

scientific article published in June 2009

Angiopoietin-like 4 is over-expressed in rheumatoid arthritis patients: association with pathological bone resorption

scientific article

Angiopoietin-like 4 promotes osteosarcoma cell proliferation and migration and stimulates osteoclastogenesis

scientific article

BRAF/MAPK and GSK3 signaling converges to control MITF nuclear export

article published in the Proceedings of the National Academy of Sciences of the United States of America

CD14− mononuclear stromal cells support (CD14+) monocyte–osteoclast differentiation in aneurysmal bone cyst

scientific article published on 13 February 2012

Cell differentiation versus cell death: extracellular glucose is a key determinant of cell fate following oxidative stress exposure

scientific article published on 20 February 2014

Chondroclasts are mature osteoclasts which are capable of cartilage matrix resorption.

scientific article

Differential regulation of HIF-mediated pathways increases mitochondrial metabolism and ATP production in hypoxic osteoclasts

scientific article published on April 2013

Effect of ascorbate on the activity of hypoxia-inducible factor in cancer cells

scientific article (publication date: 15 April 2003)

Epidermal growth factor receptor signalling contributes to osteoblastic stromal cell proliferation, osteoclastogenesis and disease progression in giant cell tumour of bone.

scientific article

Ewing sarcoma cells express RANKL and support osteoclastogenesis ⬇️

scientific article published on May 5, 2011

Hypoxia and hypoglycaemia in Ewing's sarcoma and osteosarcoma: regulation and phenotypic effects of Hypoxia-Inducible Factor

scientific article

Hypoxia-Induced Fibroblast Growth Factor 11 Stimulates Osteoclast-Mediated Resorption of Bone.

scientific article published on 18 January 2017

Hypoxia-inducible factor 1-alpha does not regulate osteoclastogenesis but enhances bone resorption activity via prolyl-4-hydroxylase 2.

scientific article published on 18 April 2017

Hypoxia-inducible factor is expressed in giant cell tumour of bone and mediates paracrine effects of hypoxia on monocyte-osteoclast differentiation via induction of VEGF.

scientific article published on May 2008

Hypoxia-inducible factor regulates osteoclast-mediated bone resorption: role of angiopoietin-like 4 ⬇️

scientific article published on July 28, 2010

Identification of differentially expressed genes in experimental models of the tumor microenvironment using differential display

scientific article published on July 1, 2001

In Vitro Generation of Mature Human Osteoclasts

scientific article published on 30 September 2011

Investigation of osteoclastogenic signalling of the RANKL substitute LIGHT.

scientific article published on 4 February 2013

KRAS p.G13D mutations are associated with sensitivity to anti-EGFR antibody treatment in colorectal cancer cell lines

scientific article

Macrophage infiltration and angiogenesis in human malignancy.

scientific article published on January 2004

Niacin induces PPARgamma expression and transcriptional activation in macrophages via HM74 and HM74a-mediated induction of prostaglandin synthesis pathways

scientific article (publication date: 28 February 2006)

Normoxic stabilization of hypoxia-inducible factor-1alpha by modulation of the labile iron pool in differentiating U937 macrophages: effect of natural resistance-associated macrophage protein 1

scientific article

Osteoblast-Osteoclast Coculture Amplifies Inhibitory Effects of FG-4592 on Human Osteoclastogenesis and Reduces Bone Resorption

scientific article published on 14 May 2020

Osteoclast formation and function in pigmented villonodular synovitis.

scientific article

RANKL-independent human osteoclast formation with APRIL, BAFF, NGF, IGF I and IGF II.

scientific article published on 28 December 2010

The Adenosine A2B Receptor Drives Osteoclast-Mediated Bone Resorption in Hypoxic Microenvironments

scientific article published on 21 June 2019

The CXCR4-CXCL12 axis in Ewing sarcoma: promotion of tumor growth rather than metastatic disease

scientific article published on 18 December 2012

Transcriptomic profiling of the myeloma bone-lining niche reveals BMP signalling inhibition to improve bone disease

scientific article published on 04 October 2019

VEGF, FLT3 ligand, PlGF and HGF can substitute for M-CSF to induce human osteoclast formation: implications for giant cell tumour pathobiology

scientific article published on 20 August 2012

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