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List of works by Timir Tripathi

A Master Regulator of α-Synuclein Aggregation

scientific article published on 01 May 2020

A combined biochemical and computational studies of the rho-class glutathione s-transferase sll1545 of Synechocystis PCC 6803.

scientific article

Abnormal Microtubule Dynamics Impair the Nuclear-Cytoplasmic Transport in Dementia

scientific article published on 20 February 2019

Activity loss by H46A mutation in Mycobacterium tuberculosis isocitrate lyase is due to decrease in structural plasticity and collective motions of the active site

scientific article published on 02 December 2017

Alterations in conformational topology and interaction dynamics caused by L418A mutation leads to activity loss of Mycobacterium tuberculosis isocitrate lyase

scientific article published on 10 June 2017

Alternate pathway to ascorbate induced inhibition of Mycobacterium tuberculosis

scientific article published on 21 June 2018

Aminoacyl-tRNA synthetases: Structure, function, and drug discovery

scientific article published on 3 January 2018

An efficient protocol to enhance recombinant protein expression using ethanol in Escherichia coli

scientific article published on 8 October 2015

An improved method for high-level soluble expression and purification of recombinant amyloid-beta peptide for in vitro studies.

scientific article

Autophagy Modulation as a Treatment of Amyloid Diseases

scientific article published on 16 September 2019

Autophagy Promotes Memory Formation

scientific article published on 18 June 2019

Biochemical and thermodynamic comparison of the selenocysteine containing and non-containing thioredoxin glutathione reductase of Fasciola gigantica

scientific article published on 8 March 2018

Characterization of a Highly pH Stable Chi-Class Glutathione S-Transferase from Synechocystis PCC 6803.

scientific article published on 12 May 2015

Cloning, soluble expression, and purification of the RNA polymerase II subunit RPB5 from Saccharomyces cerevisiae

scientific article published on 21 January 2015

Comprehensive analysis of the catalytic and structural properties of a mu-class glutathione s-transferase from Fasciola gigantica

scientific article published on 13 December 2017

Conformational stability and energetics of Plasmodium falciparum glutaredoxin

scientific article published on 17 December 2009

Current and novel therapeutic molecules and targets in Alzheimer's disease

scientific article (publication date: 2016)

Design a multi-epitope subunit vaccine for immune-protection against Leishmania parasite

scientific article published on 08 November 2020

Design of a peptide-based subunit vaccine against novel coronavirus SARS-CoV-2

scientific article published on 04 May 2020

Development of multi-epitope driven subunit vaccine against Fasciola gigantica using immunoinformatics approach

scientific article published on 04 July 2019

Direct Interaction between the β-Amyloid Core and Tau Facilitates Cross-Seeding: A Novel Target for Therapeutic Intervention

scientific article published on 16 January 2020

Distant Phe345 mutation compromises the stability and activity of Mycobacterium tuberculosis isocitrate lyase by modulating its structural flexibility

scientific article published on 21 April 2017

Draft Genome Sequence of Novosphingobium panipatense Strain P5:ABC, Isolated from Hydrocarbon-Contaminated Soil from Noonmati Refinery, Assam, India

scientific article published on 9 November 2017

Draft Genome Sequence of the Hydrocarbon-Degrading Bacterium Acinetobacter pittii Strain ABC Isolated from Noonmati Refinery, Assam, India

scientific article published on 2 November 2017

Eucalyptol, sabinene and cinnamaldehyde: potent inhibitors of salmonella target protein L-asparaginase.

scientific article published on 22 July 2017

Fasciola gigantica thioredoxin glutathione reductase: Biochemical properties and structural modeling

scientific article

Functional classification and biochemical characterization of a novel rho class glutathione S-transferase in Synechocystis PCC 6803

scientific article published on 24 November 2014

Glutathione mediated regulation of oligomeric structure and functional activity of Plasmodium falciparum glutathione S-transferase

scientific article

High Throughput Designing and Mutational Mapping of RBD-ACE2 Interface Guide Non-Conventional Therapeutic Strategies for COVID-19

scientific article published on 20 May 2020

Hotspot residues and resistance mutations in the nirmatrelvir-binding site of SARS-CoV-2 main protease: Design, identification, and correlation with globally circulating viral genomes

scientific article published in 2022

Identification and characterization of glyceraldehyde 3-phosphate dehydrogenase from Fasciola gigantica

scientific article published on 31 January 2019

Identification of novel natural inhibitors of Opisthorchis felineus cytochrome P450 using structure-based screening and molecular dynamic simulation.

scientific article

Identification of potential inhibitors of Fasciola gigantica thioredoxin1: computational screening, molecular dynamics simulation, and binding free energy studies.

scientific article published on 19 June 2017

Interaction of α-Synuclein with ATP Synthase: Switching Role from Physiological to Pathological.

scientific article published on 22 August 2018

Intrinsically Disordered Human T Lymphotropic Virus Type 1 p30 Protein: Experimental and Computational Evidence

scientific article published on 06 February 2019

Molecular Docking and In Silico ADMET Study Reveals Acylguanidine 7a as a Potential Inhibitor of β-Secretase

scientific article published on 10 April 2016

Muscarinic and nicotinic acetylcholine receptor agonists: current scenario in Alzheimer's disease therapy

scientific article published on 16 April 2018

Mycobacterium tuberculosis nucleoside diphosphate kinase shows interaction with putative ATP binding cassette (ABC) transporter, Rv1273c

scientific article published on 07 April 2019

Opisthorchis viverrini Proteome and Host-Parasite Interactions

scientific article published on 18 July 2018

Phospho-Tau Impairs Nuclear-Cytoplasmic Transport

scientific article published on 27 November 2018

Phosphorylation of PPARγ via active ERK1/2 leads to its physical association with p65 and inhibition of NF‐κβ

scientific article published on November 1, 2003

Point mutation A394E in the central intrinsic disordered region of Rna14 leads to chromosomal instability in fission yeast

scientific article published on 01 August 2018

Portrait of the Intrinsically Disordered Side of the HTLV-1 Proteome

scientific article published on 07 June 2019

Potent Inhibitors of Thioredoxin Glutathione Reductase: Grail of Anti-Schistosome Drug within Reach?

scientific article published on 11 March 2020

Preferential regeneration of thioredoxin from parasitic flatworm Fasciola gigantica using glutathione system

scientific article published on 23 September 2015

Purification and characterization of two-domain glutaredoxin in the parasitic helminth Fasciola gigantica.

scientific article

Quercetin acts as a P-gp modulator via impeding signal transduction from nucleotide-binding domain to transmembrane domain

scientific article published on 11 December 2020

Recombinant expression, purification and preliminary characterization of the mRNA export factor MEX67 of Saccharomyces cerevisiae

scientific article published on 25 November 2014

Role of the glutaredoxin domain and FAD in the stabilization of thioredoxin glutathione reductase

scientific article published on 08 September 2018

Salt-regulated reversible fibrillation of Mycobacterium tuberculosis isocitrate lyase: Concurrent restoration of structure and activity.

scientific article published on 4 June 2017

Soluble expression and purification of a full-length asparaginyl tRNA synthetase from Fasciola gigantica

scientific article published on 12 October 2017

Structural and energetic understanding of novel natural inhibitors of Mycobacterium tuberculosis malate synthase

scientific article published on 11 September 2018

Structural and stability characteristics of a monothiol glutaredoxin: glutaredoxin-like protein 1 from Plasmodium falciparum

scientific article

Structural basis of urea-induced unfolding of Fasciola gigantica glutathione S-transferase

scientific article published on 07 September 2018

Structural insights into natural compounds as inhibitors of Fasciola gigantica thioredoxin glutathione reductase

scientific article published on 20 October 2017

Structural, functional and unfolding characteristics of glutathione S-transferase of Plasmodium vivax.

scientific article published on 23 May 2009

Structure-based discovery of phenyl-diketo acids derivatives as Mycobacterium tuberculosis malate synthase inhibitors

scientific article published on 20 April 2020

Structure-based screening and molecular dynamics simulations offer novel natural compounds as potential inhibitors of Mycobacterium tuberculosis isocitrate lyase

scientific article published on 12 June 2017

Structure-function studies of the asparaginyl tRNA synthetase from Understanding the role of catalytic and non-catalytic domains

scientific article published on 09 November 2018

Synergistic Effect of Amyloid-β and Tau Disrupts Neural Circuits

scientific article published on 31 January 2019

Targeting Nucleotide Binding Domain of Multidrug Resistance-associated Protein-1 (MRP1) for the Reversal of Multi Drug Resistance in Cancer

scientific article published in Scientific Reports

The mRNA capping enzyme of Saccharomyces cerevisiae has dual specificity to interact with CTD of RNA Polymerase II.

scientific article published on 9 August 2016

UDP-N-Acetylglucosamine enolpyruvyl transferase (MurA) of Acinetobacter baumannii (AbMurA): Structural and functional properties

scientific article

Unfolding of Acinetobacter baumannii MurA proceeds through a metastable intermediate: A combined spectroscopic and computational investigation

scientific article published on 16 December 2018

Unusual thiol-based redox metabolism of parasitic flukes

scientific article published on 26 May 2016

Yeast and Human Nuclear Pore Complexes: Not So Similar After All

scientific article published on 22 June 2018