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List of works by Petri Lehenkari

1,25(OH)2D3 and calcipotriol, its hypocalcemic analog, exert a long-lasting anti-inflammatory and anti-proliferative effect in synoviocytes cultured from patients with rheumatoid arthritis and osteoarthritis.

scientific article published on 3 February 2017

17beta-estradiol induces the proliferation of the in vitro cultured human urothelium.

scientific article

3D histopathological grading of osteochondral tissue using contrast-enhanced micro-computed tomography

scientific article published on 9 June 2017

A Straightforward Method for Adipocyte Size and Count Analysis Using Open-source Software QuPath

scientific article published in 2022

A new endogenous ATP analog (ApppI) inhibits the mitochondrial adenine nucleotide translocase (ANT) and is responsible for the apoptosis induced by nitrogen-containing bisphosphonates.

scientific article published on February 2006

Activity of mesenchymal stem cells in a nonperfused cardiac explant model

scientific article published on 15 January 2013

Acute homing of bone marrow-derived mononuclear cells in intramyocardial vs. intracoronary transplantation

scientific article published on 01 December 2009

Adapting atomic force microscopy for cell biology.

scientific article

Adenosinergic Immunosuppression by Human Mesenchymal Stromal Cells Requires Co-Operation with T cells

scientific article published on 5 January 2016

Aging bone marrow mesenchymal stromal cells have altered membrane glycerophospholipid composition and functionality

scientific article published on 27 December 2012

Alendronate disturbs vesicular trafficking in osteoclasts

scientific article published on 21 December 2001

Analysis of ligand-receptor interactions in cells by atomic force microscopy

scientific article published in February 2002

Analysis of molecular changes after autologous cell therapy in swine myocardial infarction tissue can reveal novel targets for future therapy

scientific article published on 2 May 2012

Association between height and osteoarthritis of the knee and hip: The Northern Finland Birth Cohort 1966 Study

scientific article published on 10 March 2017

Association between quantitative MRI and ICRS arthroscopic grading of articular cartilage

scientific article published on 11 September 2014

Association between subchondral bone structure and osteoarthritis histopathological grade.

scientific article

Associations between MRI-defined structural pathology and generalized and localized knee pain - the Oulu Knee Osteoarthritis study

scientific article

Atomic force microscopy can be used to mechanically stimulate osteoblasts and evaluate cellular strain distributions

scientific article published on 01 January 2001

Attempt to treat congenital pseudarthrosis of the tibia with mesenchymal stromal cell transplantation

scientific article published in September 2010

Automatic Knee Osteoarthritis Diagnosis from Plain Radiographs: A Deep Learning-Based Approach

scientific article

Behaviour of nitinol in osteoblast-like ROS-17 cell cultures.

scientific article

Bone Marrow Mononuclear Cell Transplantation Restores Inflammatory Balance of Cytokines after ST Segment Elevation Myocardial Infarction

scientific article published on 21 December 2015

Bone marrow-derived mononuclear cell transplantation improves myocardial recovery by enhancing cellular recruitment and differentiation at the infarction site

scientific article published on 01 September 2007

Bone modeling and cell-material interface responses induced by nickel-titanium shape memory alloy after periosteal implantation.

scientific article published on July 1999

Bone morphogenetic proteins 4 and 2/7 induce osteogenic differentiation of mouse skin derived fibroblast and dermal papilla cells

scientific article published on 20 November 2013

Breast cancer carcinoma-associated fibroblasts differ from breast fibroblasts in immunological and extracellular matrix regulating pathways.

scientific article

CD200 positive human mesenchymal stem cells suppress TNF-alpha secretion from CD200 receptor positive macrophage-like cells

scientific article

Calcification and cellularity in human aortic heart valve tissue determine the differentiation of bone-marrow-derived cells

scientific article

Carbonic anhydrase II plays a major role in osteoclast differentiation and bone resorption by effecting the steady state intracellular pH and Ca2+

scientific journal article

Cathepsin K is present in invasive oral tongue squamous cell carcinoma in vivo and in vitro

scientific article

Cell surface structures influence lung clearance rate of systemically infused mesenchymal stromal cells

scientific article published on February 2013

Chloroquine has tumor-inhibitory and tumor-promoting effects in triple-negative breast cancer

scientific article published on 4 October 2013

Comparison of Diagnostic Performance of Semi-Quantitative Knee Ultrasound and Knee Radiography with MRI: Oulu Knee Osteoarthritis Study

scientific article

Congenital pseudarthrosis of neurofibromatosis type 1: impaired osteoblast differentiation and function and altered NF1 gene expression

scientific article published on 12 November 2008

Correlations of low-field NMR and variable-field NMR parameters with osteoarthritis in human articular cartilage under load

scientific article published on 24 May 2017

Corrigendum to "Gap junctional communication is involved in differentiation of osteoclasts from bone marrow and peripheral blood monocytes".

scientific article published on 18 May 2018

Cytokine data obtained from synovial stromal cells of patients with rheumatoid arthritis or osteoarthritis

scientific article

Determining collagen distribution in articular cartilage using contrast-enhanced micro-computed tomography

scientific article published on 20 May 2015

Different amounts of protein-bound citrulline and homocitrulline in foot joint tissues of a patient with anti-citrullinated protein antibody positive erosive rheumatoid arthritis

scientific article published on 23 September 2013

Differential effects of Ca(2+) on bisphosphonate-induced growth inhibition in breast cancer and mesothelioma cells

scientific article published on 9 December 2006

Differential synovial tissue expression of TLRs in seropositive and seronegative rheumatoid arthritis: A preliminary report

scientific article published on 30 December 2020

Doublecortin-like kinase 1-positive enterocyte - a new cell type in human intestine

scientific article

Effect of acute pancreatitis on porcine intestine: a morphological study

scientific article

Effect of bioactive extruded PLA/HA composite films on focal adhesion formation of preosteoblastic cells.

scientific article published on 19 June 2014

Effect of metal alloy surface stresses on the viability of ROS-17/2.8 osteoblastic cells.

scientific article published on September 2002

Effects of recombinant human osteogenic protein-1 on the differentiation of osteoclast-like cells and bone resorption.

scientific article published in April 1995

Electromechanical properties of human osteoarthritic and asymptomatic articular cartilage are sensitive and early detectors of degeneration.

scientific article published on 8 December 2017

Estrogen receptor alpha genotype confers interindividual variability of response to estrogen and testosterone in mesenchymal-stem-cell-derived osteoblasts

scientific article

Estrogen reduces the depth of resorption pits by disturbing the organic bone matrix degradation activity of mature osteoclasts

scientific article published in December 2001

Expansion induced microRNA changes in bone marrow mesenchymal stromal cells reveals interplay between immune regulation and cell cycle.

scientific article published on 9 November 2016

Functional diversity of endothelin pathways in human lung fibroblasts may be based on structural diversity of the endothelin receptors.

scientific article published in December 2003

Further insight into mechanism of action of clodronate: inhibition of mitochondrial ADP/ATP translocase by a nonhydrolyzable, adenine-containing metabolite.

scientific article published in May 2002

Gap junctional communication is involved in differentiation of osteoclasts from bone marrow and peripheral blood monocytes.

scientific article published on 7 May 2018

Ghrelin vaccination decreases plasma MCP-1 level in LDLR(-/-)-mice

scientific article published on 12 September 2009

Glycomics of bone marrow-derived mesenchymal stem cells can be used to evaluate their cellular differentiation stage

scientific article

Granulation tissue is altered after intramyocardial and intracoronary bone marrow-derived cell transfer for experimental acute myocardial infarction

scientific article published on 11 August 2011

HIF-1α is upregulated in human mesenchymal stem cells

scientific article published in September 2013

Healing of rabbit calvarial critical-sized defects using autogenous bone grafts and fibrin glue

scientific article published on 13 November 2014

High number of transplanted stem cells improves myocardial recovery after AMI in a porcine model.

scientific article published on 18 March 2015

High toll-like receptor (TLR) 9 expression is associated with better prognosis in surgically treated pancreatic cancer patients

scientific article published on 12 February 2017

Human CMP-N-acetylneuraminic acid hydroxylase is a novel stem cell marker linked to stem cell-specific mechanisms

scientific article

Human bone marrow mesenchymal stem cells induce collagen production and tongue cancer invasion

scientific article

Human mesenchymal stem cell derived osteoblasts degrade organic bone matrix in vitro by matrix metalloproteinases.

scientific article published on September 2005

Human mesenchymal stem cells lack tumor tropism but enhance the antitumor activity of oncolytic adenoviruses in orthotopic lung and breast tumors

scientific article published in July 2007

Imaging of Osteoarthritic Human Articular Cartilage using Fourier Transform Infrared Microspectroscopy Combined with Multivariate and Univariate Analysis

scientific article

Impaired gap junction formation and intercellular calcium signaling in urinary bladder cancer cells can be improved by Gö6976.

scientific article published on October 2007

In vitro comparison of clodronate, pamidronate and zoledronic acid effects on rat osteoclasts and human stem cell-derived osteoblasts

scientific article published on December 2005

In vitro model of bone to facilitate measurement of adhesion forces and super-resolution imaging of osteoclasts

scientific article

Increased Toll-like receptor 5 expression indicates esophageal columnar dysplasia.

scientific article published on 13 November 2013

Increased Toll-like receptor 9 expression indicates adverse prognosis in oesophageal adenocarcinoma.

scientific article published in October 2011

Increased amount of phosphorylated proinflammatory osteopontin in rheumatoid arthritis synovia is associated to decreased tartrate-resistant acid phosphatase 5B/5A ratio.

scientific article published on 08 August 2017

Inhibition of cyclooxygenase-2 down-regulates osteoclast and osteoblast differentiation and favours adipocyte formation in vitro

scientific article published on 29 June 2007

Inhibition of cytokine secretion from adipocytes by 1,25-dihydroxyvitamin D3 via the NF-κB pathway

scientific article published on 13 July 2012

Inhibition of the mevalonate pathway and activation of p38 MAP kinase are independently regulated by nitrogen-containing bisphosphonates in breast cancer cells

scientific article

Intestinal bacterial translocation and tight junction structure in acute porcine pancreatitis

scientific article published on 01 March 2012

Intra-arterial bone marrow mononuclear cell distribution in experimental global brain ischaemia.

scientific article published on 18 December 2012

Intracellular fragmentation of bone resorption products by reactive oxygen species generated by osteoclastic tartrate-resistant acid phosphatase.

scientific article

Intratumoral lactate metabolism in Barrett's esophagus and adenocarcinoma

scientific article

Invited commentary

In vivo comparison of delayed gadolinium-enhanced MRI of cartilage and delayed quantitative CT arthrography in imaging of articular cartilage.

scientific article published on 26 December 2012

Local Binary Patterns to Evaluate Trabecular Bone Structure from Micro-CT Data: Application to Studies of Human Osteoarthritis

scientific article published in 2015

Localization of nucleic acid-sensing toll-like receptors in human and mouse pancreas

scientific article

Long-term fructose feeding changes the expression of leptin receptors and autophagy genes in the adipose tissue and liver of male rats: a possible link to elevated triglycerides.

scientific article published on 02 October 2013

Low-Field NMR Relaxation Times Distributions and Their Magnetic Field Dependence as a Possible Biomarker in Cartilage

scientific article published on 13 June 2017

MRI-guidance in percutaneous core decompression of osteonecrosis of the femoral head

scientific article

MRI-guided percutaneous retrograde drilling of osteochondritis dissecans of the knee

scientific article

Magnetic resonance imaging (MRI)-defined cartilage degeneration and joint pain are associated with poor physical function in knee osteoarthritis – the Oulu Knee Osteoarthritis study

scientific article published on 08 July 2017

Mesenchymal Stromal Cells and Their Extracellular Vesicles Enhance the Anti-Inflammatory Phenotype of Regulatory Macrophages by Downregulating the Production of Interleukin (IL)-23 and IL-22.

scientific article published on 12 April 2018

Mesenchymal stromal cells from female donors enhance breast cancer cell proliferation in vitro.

scientific article published on 11 December 2014

Metabolism and phospholipid assembly of polyunsaturated fatty acids in human bone marrow mesenchymal stromal cells.

scientific article published on 16 November 2016

Methylome Analysis of Human Bone Marrow MSCs Reveals Extensive Age- and Culture-Induced Changes at Distal Regulatory Elements.

scientific article

Micro-Scale Distribution of CA4+ in Ex vivo Human Articular Cartilage Detected with Contrast-Enhanced Micro-Computed Tomography Imaging

scientific article published on 31 August 2017

Microstructural properties of bone in rat vertebra after long-term clodronate treatment

scientific article

Microtubule defects in mesenchymal stromal cells distinguish patients with Progressive Supranuclear Palsy.

scientific article published on 4 March 2018

Mitochondrial function and energy metabolism in umbilical cord blood- and bone marrow-derived mesenchymal stem cells.

scientific article published on 20 July 2011

Mitochondrial function determines the viability and osteogenic potency of human mesenchymal stem cells

scientific article published in June 2010

Monitoring mitochondrial inner membrane potential for detecting early changes in viability of bacterium-infected human bone marrow-derived mesenchymal stem cells

scientific article published on 11 December 2012

Mortalin antibody-conjugated quantum dot transfer from human mesenchymal stromal cells to breast cancer cells requires cell-cell interaction

scientific article

Multiparametric MRI assessment of human articular cartilage degeneration: Correlation with quantitative histology and mechanical properties.

scientific article

N-glycolylneuraminic acid xenoantigen contamination of human embryonic and mesenchymal stem cells is substantially reversible.

scientific article published on 28 September 2006

New technologies in scanning probe microscopy for studying molecular interactions in cells ⬇️

scientific article published on March 8, 2000

Niche matters: The comparison between bone marrow stem cells and endometrial stem cells and stromal fibroblasts reveal distinct migration and cytokine profiles in response to inflammatory stimulus.

scientific article

Novel, fast-processed crystalline and amorphous manganese oxide nanoparticles for stem cell labeling

Nuclear localization of Toll-like receptor 5 in Barrett's esophagus and esophageal adenocarcinoma is associated with metastatic behavior.

scientific article

Nucleic acid-sensing toll-like receptors 3, 7 and 8 in esophageal epithelium, barrett's esophagus, dysplasia and adenocarcinoma

scientific article published on 25 January 2016

Osteoblast recruitment from stem cells does not decrease by age at late adulthood

scientific article published in November 2003

Osteoclasts in the interface with electrospun hydroxyapatite

scientific article published on 28 August 2015

Osteogenic Differentiation of Human Mesenchymal Stem cells in a 3D Woven Scaffold

scientific article published on 11 July 2018

Osteogenic differentiation of mesenchymal stromal cells in two-dimensional and three-dimensional cultures without animal serum

scientific article

Perfluoroalkyl substances in human bone: concentrations in bones and effects on bone cell differentiation

scientific article published on 28 July 2017

Peripheral blood monocytes show increased osteoclast differentiation potential compared to bone marrow monocytes

scientific article published on 12 September 2018

Portal vein cytokines in the early phase of acute experimental oedematous and necrotizing porcine pancreatitis

scientific article published on 07 September 2012

Preliminary Report: Osteoarthritis and Rheumatoid Arthritis Synovial Fluid Increased Osteoclastogenesis <i>In Vitro</i> by Monocyte Differentiation Pathway Regulating Cytokines

scientific article published on 31 May 2022

Preparation and bioactive properties of nanocrystalline hydroxyapatite thin films obtained by conversion of atomic layer deposited calcium carbonate

scientific article published in September 2014

Production of monocytic cells from bone marrow stem cells: therapeutic usage in Alzheimer's disease

scientific article

Removal of osteoclast bone resorption products by transcytosis

scientific article

Rheumatoid arthritis antigens homocitrulline and citrulline are generated by local myeloperoxidase and peptidyl arginine deiminases 2, 3 and 4 in rheumatoid nodule and synovial tissue

scientific article published on 20 October 2016

Safety and biodistribution study of bone marrow-derived mesenchymal stromal cells and mononuclear cells and the impact of the administration route in an intact porcine model

scientific article published on 15 January 2015

Severe osteogenesis imperfecta Type-III and its challenging treatment in newborn and preschool children. A systematic review.

scientific article published on 22 April 2015

Short DNA sequences and bacterial DNA induce esophageal, gastric, and colorectal cancer cell invasion.

scientific article

Single integrin molecule adhesion forces in intact cells measured by atomic force microscopy

scientific article published on 01 June 1999

Statins and hip fracture prevention--a population based cohort study in women

scientific article

Subchondral bone histology and grading in osteoarthritis

scientific article

Targeting of biotinylated compounds to its target tissue using a low-density lipoprotein receptor-avidin fusion protein

scientific article published in December 2003

Telomeric G-quadruplex-forming DNA fragments induce TLR9-mediated and LL-37-regulated invasion in breast cancer cells in vitro.

scientific article published on 18 January 2016

Tenascin-C and fibronectin expression divide early stage tongue cancer into low- and high-risk groups

scientific article published on 17 January 2017

The Expression of Toll-like Receptors in Normal Human and Murine Gastrointestinal Organs and the Effect of Microbiome and Cancer

scientific article

The association between knee breadth and body mass: The Northern Finland Birth Cohort 1966 case study

scientific article published on 07 August 2019

The effect of bone marrow microenvironment on the functional properties of the therapeutic bone marrow-derived cells in patients with acute myocardial infarction

scientific article

The effects of bisphosphonates on the resorption cycle of isolated osteoclasts

scientific article published on 01 November 1994

The effects of tamoxifen and toremifene on bone cells involve changes in plasma membrane ion conductance

scientific article published in March 2003

The hypoxic tumor microenvironment regulates invasion of aggressive oral carcinoma cells.

scientific article

The mechanism of action of induced membranes in bone repair

scientific article published in April 2013

The regulation of pHi in osteoclasts is dependent on the culture substrate and on the stage of the resorption cycle

scientific article published on 01 June 1997

Toll-like receptor 9 expression in the natural history of Barrett mucosa

scientific article published on 03 April 2015

Toll-like receptor 9 is a novel biomarker for esophageal squamous cell dysplasia and squamous cell carcinoma progression

scientific article

Toll-like receptor 9 ligands enhance mesenchymal stem cell invasion and expression of matrix metalloprotease-13.

scientific article

Toll-like receptor 9 mediates invasion and predicts prognosis in squamous cell carcinoma of the mobile tongue

scientific article

Toll-like receptor-9 expression is inversely correlated with estrogen receptor status in breast cancer

scientific article published on 28 August 2008

Toll-like receptors 1, 2, 4 and 6 in esophageal epithelium, Barrett's esophagus, dysplasia and adenocarcinoma

scientific article published on 17 March 2016

Transient proteolytic modification of mesenchymal stromal cells increases lung clearance rate and targeting to injured tissue

scientific article published on 03 June 2013

Tumor infiltrating CD8(+) T lymphocyte count is independent of tumor TLR9 status in treatment naïve triple negative breast cancer and renal cell carcinoma

scientific article published on 22 May 2015

Tumor necrosis factor alpha promotes the expression of immunosuppressive proteins and enhances the cell growth in a human bone marrow-derived stem cell culture

scientific article published on 21 December 2010

Tumor tissue inhibitor of metalloproteinases-1 (TIMP-1) in hormone-independent breast cancer might originate in stromal cells, and improves stratification of prognosis together with nodal status

scientific article

Type XIII Collagen Strongly Affects Bone Formation in Transgenic Mice

Ultrasound arthroscopy of human knee cartilage and subchondral bone in vivo.

scientific article published on 9 July 2014

Vasculopathy in two cases of NF1-related congenital pseudarthrosis

scientific article published on 02 June 2006

Vasoactive intestinal peptide regulates osteoclast activity via specific binding sites on both osteoclasts and osteoblasts

scientific article published on 01 December 2000

Volumetric Assessment of Bone Microstructures by a 3D Local Binary Patterns –Based Method: Bone Changes with Osteoarthritis

scientific article published on 13 June 2017

Weak HIF-1alpha expression indicates poor prognosis in resectable pancreatic ductal adenocarcinoma.

scientific article published on 4 July 2018

Whole exome sequencing in Finnish families identifies new candidate genes for osteoarthritis

scientific article published in PLoS ONE

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