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List of works by Vilmantas Giedraitis

A catalog of genetic loci associated with kidney function from analyses of a million individuals

scientific article published on 31 May 2019

Abstract 4683: Smoking is associated with mosaic loss of chromosome Y

Acute sleep deprivation increases serum levels of neuron-specific enolase (NSE) and S100 calcium binding protein B (S-100B) in healthy young men.

scientific article

Adiposity as a cause of cardiovascular disease: a Mendelian randomization study

scientific article

Adult-onset autosomal dominant leukodystrophy with autonomic symptoms restricted to 1.5 Mbp on chromosome 5q23

scientific article published on 01 September 2006

Age- and sex-specific causal effects of adiposity on cardiovascular risk factors

scientific article published on 23 February 2015

Age-related somatic structural changes in the nuclear genome of human blood cells

scientific article published on 2 February 2012

Association study of cholesterol-related genes in Alzheimer's disease

scientific article published on 27 March 2007

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 01 September 2019

CALHM1 P86L polymorphism does not alter amyloid-beta or tau in cerebrospinal fluid

scientific article

CRISPR/Cas9 Mediated Disruption of the Swedish APP Allele as a Therapeutic Approach for Early-Onset Alzheimer's Disease.

scientific article

Circulating proteins as predictors of incident heart failure in the elderly

scientific article

Common genetic variants highlight the role of insulin resistance and body fat distribution in type 2 diabetes, independent of obesity

scientific article

Common variants in Alzheimer's disease and risk stratification by polygenic risk scores

scientific article published on 7 June 2021

Correction: Effect of Insulin Resistance on Monounsaturated Fatty Acid Levels: A Multi-cohort Non-targeted Metabolomics and Mendelian Randomization Study

scientific article published on 14 September 2017

Cystatin C Levels are Positively Correlated with both Aβ42 and Tau Levels in Cerebrospinal Fluid in Persons with Alzheimer's Disease, Mild Cognitive Impairment, and Healthy Controls

scholarly article by Johan Sundelöf et al published 11 August 2010 in Journal of Alzheimer's Disease

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Dual-Task Performance and Neurodegeneration: Correlations Between Timed Up-and-Go Dual-Task Test Outcomes and Alzheimer's Disease Cerebrospinal Fluid Biomarkers

scientific article published on 01 January 2019

Dual-Task Tests Predict Conversion to Dementia-A Prospective Memory-Clinic-Based Cohort Study

scientific article published on 03 November 2020

Dual-task tests discriminate between dementia, mild cognitive impairment, subjective cognitive impairment, and healthy controls - a cross-sectional cohort study

scientific article published on 29 July 2020

Effect of Insulin Resistance on Monounsaturated Fatty Acid Levels: A Multi-cohort Non-targeted Metabolomics and Mendelian Randomization Study

scientific article

Erratum: Genetic loci associated with heart rate variability and their effects on cardiac disease risk

scientific article published on 2 August 2017

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

scientific article published on 23 January 2018

Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

scientific article published on 08 October 2018

Frontotemporal dementia in a large Swedish family is caused by a progranulin null mutation

scientific article published on 15 October 2008

Further analysis of previously implicated linkage regions for Alzheimer's disease in affected relative pairs

scientific article

Genetic analysis of Alzheimer's disease in the Uppsala Longitudinal Study of Adult Men.

scientific article

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scientific article published on 17 September 2018

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies

scientific article published in 2022

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 28 February 2019

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

scientific article published in November 2018

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

scientific article published on 09 January 2020

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria

scientific article published on 11 September 2019

Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals

scientific article published on 16 October 2020

Glucose challenge metabolomics implicates medium-chain acylcarnitines in insulin resistance.

scientific article published on 6 June 2018

Higher Cathepsin B Levels in Plasma in Alzheimer's Disease Compared to Healthy Controls

scholarly article by Johan Sundelöf et al published 7 January 2011 in Journal of Alzheimer's Disease

Immune cells lacking Y chromosome have widespread dysregulation of autosomal genes

scientific article published on 18 June 2019

Immune cells lacking Y chromosome show dysregulation of autosomal gene expression

scientific article published in April 2021

Improved Differential Diagnosis of Alzheimer's Disease by Integrating ELISA and Mass Spectrometry-Based Cerebrospinal Fluid Biomarkers

Longitudinal changes in the frequency of mosaic chromosome Y loss in peripheral blood cells of aging men varies profoundly between individuals

scientific article published on 25 October 2019

Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease

scientific article

Mosaic Loss of Chromosome Y in Blood Is Associated with Alzheimer Disease

scientific article

Mosaic loss of chromosome Y in leukocytes matters

scientific article published on 01 January 2019

Mosaic loss of chromosome Y in peripheral blood is associated with shorter survival and higher risk of cancer

scientific article

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction

scientific article published on 21 May 2020

Multiplex proteomics for prediction of major cardiovascular events in type 2 diabetes

scientific article published on 24 May 2018

Mutagenesis. Smoking is associated with mosaic loss of chromosome Y.

scientific article

Neurofilament ELISA validation

scientific article published on 24 October 2009

New genetic loci link adipose and insulin biology to body fat distribution

scientific article

No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis ⬇️

scientific article published on 12 October 2016

No evidence of PGRN or MAPT gene dosage alterations in a collection of patients with frontotemporal lobar degeneration

scientific article published on 23 November 2009

Non-targeted metabolomics combined with genetic analyses identifies bile acid synthesis and phospholipid metabolism as being associated with incident type 2 diabetes

scientific article published on 12 July 2016

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

scientific article

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

article

Plasma beta amyloid and the risk of Alzheimer disease and dementia in elderly men: a prospective, population-based cohort study

scientific article published on February 2008

Protein Biomarkers for Insulin Resistance and Type 2 Diabetes Risk in Two Large Community Cohorts

scientific article

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 22 December 2017

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scholarly article published in Nature Genetics

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

erratum

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 16 March 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 01 July 2019

Rapid progression from mild cognitive impairment to Alzheimer's disease in subjects with elevated levels of tau in cerebrospinal fluid and the APOE epsilon4/epsilon4 genotype

scientific article published on 7 May 2009

Rare and low-frequency coding variants alter human adult height

scientific article (publication date: February 2017)

Rare variants in calcium homeostasis modulator 1 (CALHM1) found in early onset Alzheimer's disease patients alter calcium homeostasis

scientific article published on 17 September 2013

Rationale for a Swedish cohort consortium

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

article

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

scientific article published on 9 April 2018

Risk factors for subarachnoid haemorrhage: a nationwide cohort of 950 000 adults

scientific article published on 01 December 2019

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

scientific article published on 19 December 2017

Sharing of a conserved haplotype suggests a susceptibility gene for multiple sclerosis at chromosome 17p11.

scientific article published on April 2002

Stability of Proteins in Dried Blood Spot Biobanks

scientific article

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

scientific article published on 02 October 2019

The association between plasma proteomics and incident cardiovascular disease identifies MMP-12 as a promising cardiovascular risk marker in patients with chronic kidney disease

scientific article published on 09 July 2020

The genetic architecture of type 2 diabetes

scientific article (publication date: 11 July 2016)

The metabolites urobilin and sphingomyelin (30:1) are associated with incident heart failure in the general population

scientific article published on 30 May 2019

The normal equilibrium between CSF and plasma amyloid beta levels is disrupted in Alzheimer's disease

scientific article published on 20 September 2007

Timed Up-and-Go Dual-Task Testing in the Assessment of Cognitive Function: A Mixed Methods Observational Study for Development of the UDDGait Protocol

scientific article published on 05 March 2020

Trans-ethnic Fine Mapping Highlights Kidney-Function Genes Linked to Salt Sensitivity

scientific article

Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies

scientific article published in Nature Communications

η-Secretase processing of APP inhibits neuronal activity in the hippocampus

scientific article published on 31 August 2015

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