List of works - Eric Meggers

A Novel Copper-Mediated DNA Base Pair

scientific article (publication date: November 2000)

A second-generation copper(II)-mediated metallo-DNA-base pair

scientific article

A simple glycol nucleic acid

scientific article (publication date: 30 March 2005)

An Organometallic Inhibitor for the Human Repair Enzyme 7,8-Dihydro-8-oxoguanosine Triphosphatase

scientific article

Arylketone π-Conjugation Controls Enantioselectivity in Asymmetric Alkynylations Catalyzed by Centrochiral Ruthenium Complexes

scientific article published on 04 April 2018

Asymmetric Construction of 3,3-Disubstituted Oxindoles Bearing Vicinal Quaternary-Tertiary Carbon Stereocenters Catalyzed by a Chiral-at-Rhodium Complex

scientific article published on 29 May 2017

Asymmetric Photocatalysis by Intramolecular Hydrogen-Atom Transfer in Photoexcited Catalyst-Substrate Complex

scientific article published on 30 August 2019

Asymmetric Photocatalysis with Bis-cyclometalated Rhodium Complexes

scientific article published on 06 March 2019

Asymmetric Ring-Closing Aminooxygenation of Alkenes en Route to 2-Amino-1,3-Diols with Vicinal Stereocenters

scientific article published on 05 August 2020

Asymmetric [3+2] Photocycloadditions of Cyclopropanes with Alkenes or Alkynes via Visible Light Excitation of Catalyst-Bound Substrates.

scientific article published on 15 March 2018

Asymmetric catalysis activated by visible light

scientific article published on February 2015

Asymmetric catalysis mediated by the ligand sphere of octahedral chiral-at-metal complexes

scientific article

Asymmetric catalysis with a chiral-at-osmium complex

scientific article published on 15 June 2020

Atomic resolution duplex structure of the simplified nucleic acid GNA

scientific article

Atroposelective Synthesis of Axially Chiral N-Arylpyrroles by Chiral-at-Rhodium Catalysis

scientific article published on 03 June 2020

Bioactive cyclometalated phthalimides: design, synthesis and kinase inhibition

scientific article

Bis-Cyclometalated Indazole Chiral-at-Rhodium Catalyst for Asymmetric Photoredox Cyanoalkylations

scientific article published on 13 November 2019

Catalytic Asymmetric Dearomatization by Visible-Light-Activated [2+2] Photocycloaddition

scientific article published on 6 April 2018

Catalytic Enantioselective Intramolecular C(sp3 )-H Amination of 2-Azidoacetamides

scientific article published on 20 December 2018

Catalytic asymmetric synthesis of a nitrogen heterocycle through stereocontrolled direct photoreaction from electronically excited state

scientific article published on 21 December 2017

Chiral auxiliaries as emerging tools for the asymmetric synthesis of octahedral metal complexes

scientific article published on January 2010

Chiral-at-Iron Catalyst: Expanding the Chemical Space for Asymmetric Earth-Abundant Metal Catalysis

scientific article published on 06 March 2019

Combining the catalytic enantioselective reaction of visible-light-generated radicals with a by-product utilization system.

scientific article published in September 2017

Crystal structure of the PIM2 kinase in complex with an organoruthenium inhibitor

scientific article

Development of organometallic S6K1 inhibitors

scientific article

Direct Visible-Light-Excited Asymmetric Lewis Acid Catalysis of Intermolecular [2+2] Photocycloadditions

scientific article published on 23 June 2017

Discovery of a strongly apoptotic ruthenium complex through combinatorial coordination chemistry

scientific article

Duplex Structure of a Minimal Nucleic Acid

scientific article

Enantioselective 2-Alkylation of 3-Substituted Indoles with Dual Chiral Lewis Acid/Hydrogen-Bond-Mediated Catalyst.

scientific article published on 27 December 2016

Enantioselective Alkynylation of Aromatic Aldehydes Catalyzed by a Sterically Highly Demanding Chiral-at-Rhodium Lewis Acid

scientific article published on 31 July 2017

Enantioselective catalytic β-amination through proton-coupled electron transfer followed by stereocontrolled radical-radical coupling

scientific article published on 15 June 2017

Enantioselective intramolecular C-H amination of aliphatic azides by dual ruthenium and phosphine catalysis

scientific article published on 29 January 2019

Exploiting Octahedral Stereocenters: From Enzyme Inhibition to Asymmetric Photoredox Catalysis

scientific article published on 22 March 2017

Exploring biologically relevant chemical space with metal complexes

scientific article

Extremely Tight Binding of a Ruthenium Complex to Glycogen Synthase Kinase 3

scientific article

From conventional to unusual enzyme inhibitor scaffolds: the quest for target specificity

scientific article published on February 15, 2011

From imide to lactam metallo-pyridocarbazoles: distinct scaffolds for the design of selective protein kinase inhibitors

scientific article published on December 2009

GSK3β inhibition blocks melanoma cell/host interactions by downregulating N-cadherin expression and decreasing FAK phosphorylation

scientific article published on 19 July 2012

Kinetic Resolution of Epoxides with CO2 Catalyzed by a Chiral-at-Iridium Complex

scientific article published on 21 November 2018

Metal complex catalysis in living biological systems ⬇️

scientific article published on February 25, 2013

Metal complexes as structural templates for targeting proteins

scientific article published on 19 February 2014

Non-ATP-Mimetic Organometallic Protein Kinase Inhibitor

scientific article

Non-C2-Symmetric Chiral-at-Ruthenium Catalyst for Highly Efficient Enantioselective Intramolecular C(sp3)-H Amidation

scientific article published on 21 November 2019

Octahedral Ruthenium Complex with Exclusive Metal-Centered Chirality for Highly Effective Asymmetric Catalysis.

scientific article published on 14 March 2017

On the structure and dynamics of duplex GNA

scientific article

Organometallic Pyridylnaphthalimide Complexes as Protein Kinase Inhibitors

scientific article

Origins of Enantioselectivity in Asymmetric Radical Additions to Octahedral Chiral-at-Rhodium Enolates: A Computational Study.

scientific article

PIM kinases as therapeutic targets against advanced melanoma

scientific article published on 19 July 2016

PIM1 kinase as a target for cancer therapy ⬇️

scientific article published on March 4, 2012

Preparation of chiral-at-metal catalysts and their use in asymmetric photoredox chemistry.

scientific article published in March 2018

Progress toward an expanded eukaryotic genetic code

scientific article

Rhenium Complexes with Red-Light-Induced Anticancer Activity

scientific article

Rhenium complexes with visible-light-induced anticancer activity

scientific article published on 8 April 2013

Ruthenium Pybox-Catalyzed Enantioselective Intramolecular C-H Amination of Sulfamoyl Azides en Route to Chiral Vicinal Diamines

scientific article published on 25 November 2020

Ruthenium half-sandwich complexes as protein kinase inhibitors: an N-succinimidyl ester for rapid derivatizations of the cyclopentadienyl moiety

scientific article

Ruthenium half-sandwich complexes as protein kinase inhibitors: derivatization of the pyridocarbazole pharmacophore ligand

scientific article

Ruthenium half-sandwich complexes bound to protein kinase Pim-1

scientific article

Similar Biological Activities of Two Isostructural Ruthenium and Osmium Complexes

scientific article

Solid-phase synthesis of tris-heteroleptic ruthenium(II) complexes and application to acetylcholinesterase inhibition

scientific article

Steering Asymmetric Lewis Acid Catalysis Exclusively with Octahedral Metal-Centered Chirality

scientific article published on 27 January 2017

Structurally Sophisticated Octahedral Metal Complexes as Highly Selective Protein Kinase Inhibitors

scientific article

Structure of anticancer ruthenium half-sandwich complex bound to glycogen synthase kinase 3β

scientific article

Structure-Based Design of an Organoruthenium Phosphatidyl-inositol-3-kinase Inhibitor Reveals a Switch Governing Lipid Kinase Potency and Selectivity

scientific article

Synthesis and cyclometalation of a pyrido[3,2-e]-2,10b-diaza-cyclopenta[c]fluorene-1,3-dione scaffold

scientific article

Synthesis of cyclopentadienyl ruthenium complexes bearing pendant chelating picolinates through an electrophilic precursor

scientific article published on February 2008

Synthesis of β-Substituted γ-Aminobutyric Acid Derivatives through Enantioselective Photoredox Catalysis

scientific article published on 30 July 2018

Targeting Large Kinase Active Site with Rigid, Bulky Octahedral Ruthenium Complexes

scientific article

Targeting proteins with metal complexes

scientific article published on 12 January 2009

The Art of Filling Protein Pockets Efficiently with Octahedral Metal Complexes

scientific article

The Crystal Structure of BRAF in Complex with an Organoruthenium Inhibitor Reveals a Mechanism for Inhibition of an Active Form of BRAF Kinase

scientific article

Transition-metal-mediated uncaging in living human cells—an emerging alternative to photolabile protecting groups

scientific article published on 02 January 2015

Understanding Rate Acceleration and Stereoinduction of an Asymmetric Giese Reaction Mediated by a Chiral Rhodium Catalyst.

scientific article published on 31 May 2017

Unusual eta2-allene osmacycle with apoptotic properties

scientific article

Visible-Light-Activated Asymmetric β-C-H Functionalization of Acceptor-Substituted Ketones with 1,2-Dicarbonyl Compounds.

scientific article published on 21 November 2017

Visible-Light-Activated Catalytic Enantioselective β-Alkylation of α,β-Unsaturated 2-Acyl Imidazoles Using Hantzsch Esters as Radical Reservoirs

scientific article published on 20 July 2018

List of works by Eric Meggers

A Novel Copper-Mediated DNA Base Pair

A second-generation copper(II)-mediated metallo-DNA-base pair

A simple glycol nucleic acid

An Organometallic Inhibitor for the Human Repair Enzyme 7,8-Dihydro-8-oxoguanosine Triphosphatase

Arylketone π-Conjugation Controls Enantioselectivity in Asymmetric Alkynylations Catalyzed by Centrochiral Ruthenium Complexes

Asymmetric Construction of 3,3-Disubstituted Oxindoles Bearing Vicinal Quaternary-Tertiary Carbon Stereocenters Catalyzed by a Chiral-at-Rhodium Complex

Asymmetric Photocatalysis by Intramolecular Hydrogen-Atom Transfer in Photoexcited Catalyst-Substrate Complex

Asymmetric Photocatalysis with Bis-cyclometalated Rhodium Complexes

Asymmetric Ring-Closing Aminooxygenation of Alkenes en Route to 2-Amino-1,3-Diols with Vicinal Stereocenters

Asymmetric [3+2] Photocycloadditions of Cyclopropanes with Alkenes or Alkynes via Visible Light Excitation of Catalyst-Bound Substrates.

Asymmetric catalysis activated by visible light

Asymmetric catalysis mediated by the ligand sphere of octahedral chiral-at-metal complexes

Asymmetric catalysis with a chiral-at-osmium complex

Atomic resolution duplex structure of the simplified nucleic acid GNA

Atroposelective Synthesis of Axially Chiral N-Arylpyrroles by Chiral-at-Rhodium Catalysis

Bioactive cyclometalated phthalimides: design, synthesis and kinase inhibition

Bis-Cyclometalated Indazole Chiral-at-Rhodium Catalyst for Asymmetric Photoredox Cyanoalkylations

Catalytic Asymmetric Dearomatization by Visible-Light-Activated [2+2] Photocycloaddition

Catalytic Enantioselective Intramolecular C(sp3 )-H Amination of 2-Azidoacetamides

Catalytic asymmetric synthesis of a nitrogen heterocycle through stereocontrolled direct photoreaction from electronically excited state

Chiral auxiliaries as emerging tools for the asymmetric synthesis of octahedral metal complexes

Chiral-at-Iron Catalyst: Expanding the Chemical Space for Asymmetric Earth-Abundant Metal Catalysis

Combining the catalytic enantioselective reaction of visible-light-generated radicals with a by-product utilization system.

Crystal structure of the PIM2 kinase in complex with an organoruthenium inhibitor

Development of organometallic S6K1 inhibitors

Direct Visible-Light-Excited Asymmetric Lewis Acid Catalysis of Intermolecular [2+2] Photocycloadditions

Discovery of a strongly apoptotic ruthenium complex through combinatorial coordination chemistry

Duplex Structure of a Minimal Nucleic Acid

Enantioselective 2-Alkylation of 3-Substituted Indoles with Dual Chiral Lewis Acid/Hydrogen-Bond-Mediated Catalyst.

Enantioselective Alkynylation of Aromatic Aldehydes Catalyzed by a Sterically Highly Demanding Chiral-at-Rhodium Lewis Acid

Enantioselective catalytic β-amination through proton-coupled electron transfer followed by stereocontrolled radical-radical coupling

Enantioselective intramolecular C-H amination of aliphatic azides by dual ruthenium and phosphine catalysis

Exploiting Octahedral Stereocenters: From Enzyme Inhibition to Asymmetric Photoredox Catalysis

Exploring biologically relevant chemical space with metal complexes

Extremely Tight Binding of a Ruthenium Complex to Glycogen Synthase Kinase 3

From conventional to unusual enzyme inhibitor scaffolds: the quest for target specificity

From imide to lactam metallo-pyridocarbazoles: distinct scaffolds for the design of selective protein kinase inhibitors

GSK3β inhibition blocks melanoma cell/host interactions by downregulating N-cadherin expression and decreasing FAK phosphorylation

Kinetic Resolution of Epoxides with CO2 Catalyzed by a Chiral-at-Iridium Complex

Metal complex catalysis in living biological systems ⬇️

Metal complexes as structural templates for targeting proteins

Non-ATP-Mimetic Organometallic Protein Kinase Inhibitor

Non-C2-Symmetric Chiral-at-Ruthenium Catalyst for Highly Efficient Enantioselective Intramolecular C(sp3)-H Amidation

Octahedral Ruthenium Complex with Exclusive Metal-Centered Chirality for Highly Effective Asymmetric Catalysis.

On the structure and dynamics of duplex GNA

Organometallic Pyridylnaphthalimide Complexes as Protein Kinase Inhibitors

Origins of Enantioselectivity in Asymmetric Radical Additions to Octahedral Chiral-at-Rhodium Enolates: A Computational Study.

PIM kinases as therapeutic targets against advanced melanoma

PIM1 kinase as a target for cancer therapy ⬇️

Preparation of chiral-at-metal catalysts and their use in asymmetric photoredox chemistry.

Progress toward an expanded eukaryotic genetic code

Rhenium Complexes with Red-Light-Induced Anticancer Activity

Rhenium complexes with visible-light-induced anticancer activity

Ruthenium Pybox-Catalyzed Enantioselective Intramolecular C-H Amination of Sulfamoyl Azides en Route to Chiral Vicinal Diamines

Ruthenium half-sandwich complexes as protein kinase inhibitors: an N-succinimidyl ester for rapid derivatizations of the cyclopentadienyl moiety

Ruthenium half-sandwich complexes as protein kinase inhibitors: derivatization of the pyridocarbazole pharmacophore ligand

Ruthenium half-sandwich complexes bound to protein kinase Pim-1

Similar Biological Activities of Two Isostructural Ruthenium and Osmium Complexes

Solid-phase synthesis of tris-heteroleptic ruthenium(II) complexes and application to acetylcholinesterase inhibition

Steering Asymmetric Lewis Acid Catalysis Exclusively with Octahedral Metal-Centered Chirality

Structurally Sophisticated Octahedral Metal Complexes as Highly Selective Protein Kinase Inhibitors

Structure of anticancer ruthenium half-sandwich complex bound to glycogen synthase kinase 3β

Structure-Based Design of an Organoruthenium Phosphatidyl-inositol-3-kinase Inhibitor Reveals a Switch Governing Lipid Kinase Potency and Selectivity

Synthesis and cyclometalation of a pyrido[3,2-e]-2,10b-diaza-cyclopenta[c]fluorene-1,3-dione scaffold

Synthesis of cyclopentadienyl ruthenium complexes bearing pendant chelating picolinates through an electrophilic precursor

Synthesis of β-Substituted γ-Aminobutyric Acid Derivatives through Enantioselective Photoredox Catalysis

Targeting Large Kinase Active Site with Rigid, Bulky Octahedral Ruthenium Complexes

Targeting proteins with metal complexes

The Art of Filling Protein Pockets Efficiently with Octahedral Metal Complexes

The Crystal Structure of BRAF in Complex with an Organoruthenium Inhibitor Reveals a Mechanism for Inhibition of an Active Form of BRAF Kinase

Transition-metal-mediated uncaging in living human cells—an emerging alternative to photolabile protecting groups

Understanding Rate Acceleration and Stereoinduction of an Asymmetric Giese Reaction Mediated by a Chiral Rhodium Catalyst.

Unusual eta2-allene osmacycle with apoptotic properties

Visible-Light-Activated Asymmetric β-C-H Functionalization of Acceptor-Substituted Ketones with 1,2-Dicarbonyl Compounds.

Visible-Light-Activated Catalytic Enantioselective β-Alkylation of α,β-Unsaturated 2-Acyl Imidazoles Using Hantzsch Esters as Radical Reservoirs