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List of works by Anna Tsimelzon

A phase II neoadjuvant trial of anastrozole, fulvestrant, and gefitinib in patients with newly diagnosed estrogen receptor positive breast cancer

scientific article published on 27 July 2011

A renewable tissue resource of phenotypically stable, biologically and ethnically diverse, patient-derived human breast cancer xenograft models

scientific article published on 04 June 2013

Ablation of steroid receptor coactivator-3 resembles the human CACT metabolic myopathy

scientific article

Alterations of gene expression in the development of early hyperplastic precursors of breast cancer

scientific article published in July 2007

Analysis of phosphatases in ER-negative breast cancers identifies DUSP4 as a critical regulator of growth and invasion

scientific article published on 08 July 2016

Androgen receptor overexpression induces tamoxifen resistance in human breast cancer cells

scientific article

Androgen receptor promotes tamoxifen agonist activity by activation of EGFR in ERα-positive breast cancer

scientific article published on 20 October 2015

CAPER is vital for energy and redox homeostasis by integrating glucose-induced mitochondrial functions via ERR-α-Gabpa and stress-induced adaptive responses via NF-κB-cMYC

scientific article

Comprehensive genomic analysis identifies novel subtypes and targets of triple-negative breast cancer

scientific article

Decreased TGFbeta signaling and increased COX2 expression in high risk women with increased mammographic breast density

scientific article published on 25 February 2009

Development of resistance to targeted therapies transforms the clinically associated molecular profile subtype of breast tumor xenografts

scientific article published on September 2008

Dicer-mediated upregulation of BCRP confers tamoxifen resistance in human breast cancer cells

scientific article published on 30 August 2011

ESR1 mutations affect anti-proliferative responses to tamoxifen through enhanced cross-talk with IGF signaling

scientific article

Elevated expression of mitogen-activated protein kinase phosphatase 3 in breast tumors: a mechanism of tamoxifen resistance

scientific article published on June 2006

Estrogen and insulin-like growth factor-I (IGF-I) independently down-regulate critical repressors of breast cancer growth

scientific article published on 04 May 2011

FOXA1 overexpression mediates endocrine resistance by altering the ER transcriptome and IL-8 expression in ER-positive breast cancer

scientific article published on 06 October 2016

Growth of triple-negative breast cancer cells relies upon coordinate autocrine expression of the proinflammatory cytokines IL-6 and IL-8.

scientific article published on 30 April 2013

HER2 Signaling Drives DNA Anabolism and Proliferation through SRC-3 Phosphorylation and E2F1-Regulated Genes

scientific article

High IGF-IR activity in triple-negative breast cancer cell lines and tumorgrafts correlates with sensitivity to anti-IGF-IR therapy

scientific article

Identification of novel kinase targets for the treatment of estrogen receptor-negative breast cancer

scientific article published on 06 October 2009

Identification of tumor-initiating cells in a p53-null mouse model of breast cancer

scientific article published on June 2008

Intratumoral heterogeneity in a Trp53-null mouse model of human breast cancer

scientific article published on 3 March 2015

Loss of Rho GDIα and resistance to tamoxifen via effects on estrogen receptor α

scientific article

Metastasis tumor-associated protein 2 enhances metastatic behavior and is associated with poor outcomes in estrogen receptor-negative breast cancer

scientific article published on 28 September 2013

Patterns of resistance and incomplete response to docetaxel by gene expression profiling in breast cancer patients

scientific article

Phosphatase PTP4A3 Promotes Triple-Negative Breast Cancer Growth and Predicts Poor Patient Survival

scientific article published on 26 February 2016

Research Resource: A Reference Transcriptome for Constitutive Androstane Receptor and Pregnane X Receptor Xenobiotic Signaling

scientific article

Research Resource: Roles for Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CaMKK2) in Systems Metabolism

scientific article published on 22 March 2016

Research resource: expression profiling reveals unexpected targets and functions of the human steroid receptor RNA activator (SRA) gene

scientific article

Research resource: tissue- and pathway-specific metabolomic profiles of the steroid receptor coactivator (SRC) family

scientific article published on 11 January 2013

SAFB1 mediates repression of immune regulators and apoptotic genes in breast cancer cells

scientific article

SRC-2 coactivator deficiency decreases functional reserve in response to pressure overload of mouse heart

scientific article (publication date: 2012)

Tamoxifen resistance in breast tumors is driven by growth factor receptor signaling with repression of classic estrogen receptor genomic function

scientific article

The SOX11 transcription factor is a critical regulator of basal-like breast cancer growth, invasion, and basal-like gene expression

scientific article published on 17 February 2016

Transcriptional profiling of mammary gland side population cells

scientific article

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