List of works - Alfonso Carotenuto

1H and 15N sequential assignment and secondary structure of the monomeric N67D mutant of bovine seminal ribonuclease

article

A different molecular mechanism underlying antimicrobial and hemolytic actions of temporins A and L.

scientific article

A new, potent urotensin II receptor peptide agonist containing a Pen residue at the disulfide bridge

scientific article published in September 2002

A novel route to synthesize Freidinger lactams by micowave irradiation*

scientific article published on 01 November 2005

Alanine scanning analysis and structure-function relationships of the frog-skin antimicrobial peptide temporin-1Ta

article

Amino Acid derivatives as new zinc binding groups for the design of selective matrix metalloproteinase inhibitors.

scientific article

An N-glucosylated peptide detecting disease-specific autoantibodies, biomarkers of multiple sclerosis

scientific article

An ancestral host defence peptide within human β-defensin 3 recapitulates the antibacterial and antiviral activity of the full-length molecule

scientific article published on 21 December 2015

An investigation into the origin of the biased agonism associated with the urotensin II receptor activation

scientific article

Antiproliferative Sesterterpenes from the Caribbean Sponge Cacospongia cf. linteiformis ⬇️

scientific article published on February 1, 1998

Apoptosis therapy in cancer: the first single-molecule co-activating p53 and the translocator protein in glioblastoma.

scientific article published on 23 April 2014

Breast Tumor Cell Invasion and Pro-Invasive Activity of Cancer-Associated Fibroblasts Co-Targeted by Novel Urokinase-Derived Decapeptides

scientific article published on 24 August 2020

Characterization of a selective CaMKII peptide inhibitor

scientific article published on 22 January 2013

Conformation-activity relationship of designed glycopeptides as synthetic probes for the detection of autoantibodies, biomarkers of multiple sclerosis

scientific article

Conformational analysis of a glycosylated human myelin oligodendrocyte glycoprotein peptide epitope able to detect antibody response in multiple sclerosis.

scientific article

Conformational study on cyclic melanocortin ligands and new insight into their binding mode at the MC4 receptor

scientific article

Correction to New Anticancer Agents Mimicking Protein Recognition Motifs

scientific article published on 30 April 2015

De novo designed library of linear helical peptides: an exploratory tool in the discovery of protein-protein interaction modulators

scientific article

Design and Synthesis of Small Libraries of Peptidomimetics Based on a Thiazolidine Moiety

Design and synthesis of spirotryprostatin-inspired diketopiperazine systems from prolyl spirooxoindolethiazolidine derivatives

scientific article published on 29 April 2010

Design, Synthesis, Conformational Analysis, and Biological Studies of Urotensin-II Lactam Analogues

article

Design, synthesis and efficacy of novel G protein-coupled receptor kinase 2 inhibitors

scientific article

Design, synthesis, and cytotoxic evaluation of a new series of 3-substituted spiro[(dihydropyrazine-2,5-dione)-6,3'-(2',3'-dihydrothieno[2,3-b]naphtho-4',9'-dione)] derivatives

scientific article published on 22 March 2007

Design, synthesis, and cytotoxic evaluation of acyl derivatives of 3-aminonaphtho[2,3-b]thiophene-4,9-dione, a quinone-based system

scientific article published on 23 May 2011

Designed glucopeptides mimetics of myelin protein epitopes as synthetic probes for the detection of autoantibodies, biomarkers of multiple sclerosis.

scientific article published on 3 December 2012

Designed glycopeptides with different beta-turn types as synthetic probes for the detection of autoantibodies as biomarkers of multiple sclerosis

scientific article published on 20 August 2008

Development of Macrocyclic Peptidomimetics Containing Constrained α,α-Dialkylated Amino Acids with Potent and Selective Activity at Human Melanocortin Receptors.

scientific article

Development of antiviral fusion inhibitors: short modified peptides derived from the transmembrane glycoprotein of feline immunodeficiency virus

scientific article published in May 2006

Discovery of Novel Potent and Selective Agonists at the Melanocortin-3 Receptor

scientific article published on 24 November 2015

Discovery of PTPRJ agonist peptides that effectively inhibit in vitro cancer cell proliferation and tube formation

scientific article

Exploring the N-Terminal Region of C-X-C Motif Chemokine 12 (CXCL12): Identification of Plasma-Stable Cyclic Peptides As Novel, Potent C-X-C Chemokine Receptor Type 4 (CXCR4) Antagonists

scientific article

Functional Selectivity Revealed by N-Methylation Scanning of Human Urotensin II and Related Peptides

scientific article published on 23 January 2019

Identification of the spiro(oxindole-3,3'-thiazolidine)-based derivatives as potential p53 activity modulators

scientific article published on 8 November 2010

Isolation and functional characterization of peptide agonists of PTPRJ, a tyrosine phosphatase receptor endowed with tumor suppressor activity

scientific article

Lead Optimization of P5U and Urantide: Discovery of Novel Potent Ligands at the Urotensin-II Receptor

scientific article published on 10 July 2014

Ligand-Based NMR Study of C-X-C Chemokine Receptor Type 4 (CXCR4)-Ligand Interactions on Living Cancer Cells

scientific article published on 9 March 2018

Lipidated peptides derived from intracellular loops 2 and 3 of the urotensin II receptor act as biased allosteric ligands

scientific article published on 10 August 2021

Morphiceptin analogues containing a dipeptide mimetic structure: an investigation on the bioactive topology at the mu-receptor

scientific article published in May 2005

Native PAGE to study the interaction between the oncosuppressor p53 and its protein ligands

scientific article published on 02 January 2015

New anticancer agents mimicking protein recognition motifs

scientific article published on 19 August 2013

New insight into the binding mode of peptide ligands at Urotensin-II receptor: structure-activity relationships study on P5U and urantide

scientific article

New insight into the binding mode of peptides at urotensin-II receptor by Trp-constrained analogues of P5U and urantide

scientific article published on 25 March 2013

New insight into the mechanism of action of the temporin antimicrobial peptides

scientific article

Novel cyclic biphalin analogue with improved antinociceptive properties.

scientific article published on 14 July 2014

Novel octreotide dicarba-analogues with high affinity and different selectivity for somatostatin receptors

scientific article published on August 2010

Novel sst5-selective somatostatin dicarba-analogues: synthesis and conformation-affinity relationships

scientific article published on 23 January 2008

Novel α-MSH peptide analogues with broad spectrum antimicrobial activity

scientific article

Opposite modulation of cell migration by distinct subregions of urokinase connecting peptide

scientific article published on 20 March 2013

Porrigenins A and B, novel cytotoxic and antiproliferative sapogenins isolated from Allium porrum

scientific article published on 01 October 1997

Retroinverso analogue of the antiviral octapeptide C8 inhibits feline immunodeficiency virus in serum.

scientific article published in May 2003

SAR study and conformational analysis of a series of novel peptide G protein-coupled receptor kinase 2 inhibitors

scientific article published in January 2014

Sequence-specific 1H, 13C and 15N assignment and secondary structure of the apo EH2 domain of mouse Eps15

scientific article published on 01 May 1999

Spiro[(dihydropyrazin-2,5-dione)-6,3'-(2',3'-dihydrothieno[2,3-b]naphtho-4',9'-dione)]-based cytotoxic agents: structure-activity relationship studies on the substituent at N4-position of the diketopiperazine domain

scientific article

Spirostanol saponins of Allium porrum L

scientific article published on 01 August 1999

Structural studies on Hgr3 orphan receptor ligand prolactin-releasing peptide

scientific article

Structure-Activity Relationship Studies, SPR Affinity Characterization, and Conformational Analysis of Peptides That Mimic the HNK-1 Carbohydrate Epitope.

scientific article published on 12 April 2017

Structure-Activity Relationships and Biological Characterization of a Novel, Potent, and Serum Stable C-X-C Chemokine Receptor Type 4 (CXCR4) Antagonist

scientific article published on 10 November 2017

Structure-activity relationship, conformational and biological studies of temporin L analogues

scientific article

Structure?function Relationships and Conformational Properties of ?-MSH(6?13) Analogues with Candidacidal Activity

scientific article published on 01 January 2007

Structures and micelle locations of the nonlipidated and lipidated C-terminal membrane anchor of 2',3'-cyclic nucleotide-3'-phosphodiesterase

scientific article published on 13 December 2007

Synthesis and pharmacological evaluation of some 4-oxo-quinoline-2-carboxylic acid derivatives as anti-inflammatory and analgesic agents

scientific article published on October 2010

Synthesis, in vitro, and in cell studies of a new series of [indoline-3,2'-thiazolidine]-based p53 modulators

scientific article published on 26 June 2013

The effect of d-amino acid substitution on the selectivity of temporin L towards target cells: identification of a potent anti-Candida peptide

scientific article published on 10 September 2012

The flavonoids of Allium neapolitanum

scientific article published on 01 March 1997

The flavonoids of Allium ursinum

scientific article published on 01 February 1996

Unraveling the Active Conformation of Urotensin II

Unraveling the active conformation of urotensin II.

scientific article published in March 2004

Urantide conformation and interaction with the urotensin-II receptor.

scientific article

Urokinase receptor derived peptides as potent inhibitors of the formyl peptide receptor type 1-triggered cell migration.

scientific article published in December 2017

Urotensin-II receptor antagonists.

scientific article

Urotensin-II receptor ligands. From agonist to antagonist activity

scientific article published in November 2005

Urotensin-II receptor peptide agonists

scientific article published in September 2004

List of works by Alfonso Carotenuto

1H and 15N sequential assignment and secondary structure of the monomeric N67D mutant of bovine seminal ribonuclease

A different molecular mechanism underlying antimicrobial and hemolytic actions of temporins A and L.

A new, potent urotensin II receptor peptide agonist containing a Pen residue at the disulfide bridge

A novel route to synthesize Freidinger lactams by micowave irradiation*

Alanine scanning analysis and structure-function relationships of the frog-skin antimicrobial peptide temporin-1Ta

Amino Acid derivatives as new zinc binding groups for the design of selective matrix metalloproteinase inhibitors.

An N-glucosylated peptide detecting disease-specific autoantibodies, biomarkers of multiple sclerosis

An ancestral host defence peptide within human β-defensin 3 recapitulates the antibacterial and antiviral activity of the full-length molecule

An investigation into the origin of the biased agonism associated with the urotensin II receptor activation

Antiproliferative Sesterterpenes from the Caribbean Sponge Cacospongia cf. linteiformis ⬇️

Apoptosis therapy in cancer: the first single-molecule co-activating p53 and the translocator protein in glioblastoma.

Breast Tumor Cell Invasion and Pro-Invasive Activity of Cancer-Associated Fibroblasts Co-Targeted by Novel Urokinase-Derived Decapeptides

Characterization of a selective CaMKII peptide inhibitor

Conformation-activity relationship of designed glycopeptides as synthetic probes for the detection of autoantibodies, biomarkers of multiple sclerosis

Conformational analysis of a glycosylated human myelin oligodendrocyte glycoprotein peptide epitope able to detect antibody response in multiple sclerosis.

Conformational study on cyclic melanocortin ligands and new insight into their binding mode at the MC4 receptor

Correction to New Anticancer Agents Mimicking Protein Recognition Motifs

De novo designed library of linear helical peptides: an exploratory tool in the discovery of protein-protein interaction modulators

Design and Synthesis of Small Libraries of Peptidomimetics Based on a Thiazolidine Moiety

Design and synthesis of spirotryprostatin-inspired diketopiperazine systems from prolyl spirooxoindolethiazolidine derivatives

Design, Synthesis, Conformational Analysis, and Biological Studies of Urotensin-II Lactam Analogues

Design, synthesis and efficacy of novel G protein-coupled receptor kinase 2 inhibitors

Design, synthesis, and cytotoxic evaluation of a new series of 3-substituted spiro[(dihydropyrazine-2,5-dione)-6,3'-(2',3'-dihydrothieno[2,3-b]naphtho-4',9'-dione)] derivatives

Design, synthesis, and cytotoxic evaluation of acyl derivatives of 3-aminonaphtho[2,3-b]thiophene-4,9-dione, a quinone-based system

Designed glucopeptides mimetics of myelin protein epitopes as synthetic probes for the detection of autoantibodies, biomarkers of multiple sclerosis.

Designed glycopeptides with different beta-turn types as synthetic probes for the detection of autoantibodies as biomarkers of multiple sclerosis

Development of Macrocyclic Peptidomimetics Containing Constrained α,α-Dialkylated Amino Acids with Potent and Selective Activity at Human Melanocortin Receptors.

Development of antiviral fusion inhibitors: short modified peptides derived from the transmembrane glycoprotein of feline immunodeficiency virus

Discovery of Novel Potent and Selective Agonists at the Melanocortin-3 Receptor

Discovery of PTPRJ agonist peptides that effectively inhibit in vitro cancer cell proliferation and tube formation

Exploring the N-Terminal Region of C-X-C Motif Chemokine 12 (CXCL12): Identification of Plasma-Stable Cyclic Peptides As Novel, Potent C-X-C Chemokine Receptor Type 4 (CXCR4) Antagonists

Functional Selectivity Revealed by N-Methylation Scanning of Human Urotensin II and Related Peptides

Identification of the spiro(oxindole-3,3'-thiazolidine)-based derivatives as potential p53 activity modulators

Isolation and functional characterization of peptide agonists of PTPRJ, a tyrosine phosphatase receptor endowed with tumor suppressor activity

Lead Optimization of P5U and Urantide: Discovery of Novel Potent Ligands at the Urotensin-II Receptor

Ligand-Based NMR Study of C-X-C Chemokine Receptor Type 4 (CXCR4)-Ligand Interactions on Living Cancer Cells

Lipidated peptides derived from intracellular loops 2 and 3 of the urotensin II receptor act as biased allosteric ligands

Morphiceptin analogues containing a dipeptide mimetic structure: an investigation on the bioactive topology at the mu-receptor

Native PAGE to study the interaction between the oncosuppressor p53 and its protein ligands

New anticancer agents mimicking protein recognition motifs

New insight into the binding mode of peptide ligands at Urotensin-II receptor: structure-activity relationships study on P5U and urantide

New insight into the binding mode of peptides at urotensin-II receptor by Trp-constrained analogues of P5U and urantide

New insight into the mechanism of action of the temporin antimicrobial peptides

Novel cyclic biphalin analogue with improved antinociceptive properties.

Novel octreotide dicarba-analogues with high affinity and different selectivity for somatostatin receptors

Novel sst5-selective somatostatin dicarba-analogues: synthesis and conformation-affinity relationships

Novel α-MSH peptide analogues with broad spectrum antimicrobial activity

Opposite modulation of cell migration by distinct subregions of urokinase connecting peptide

Porrigenins A and B, novel cytotoxic and antiproliferative sapogenins isolated from Allium porrum

Retroinverso analogue of the antiviral octapeptide C8 inhibits feline immunodeficiency virus in serum.

SAR study and conformational analysis of a series of novel peptide G protein-coupled receptor kinase 2 inhibitors

Sequence-specific 1H, 13C and 15N assignment and secondary structure of the apo EH2 domain of mouse Eps15

Spiro[(dihydropyrazin-2,5-dione)-6,3'-(2',3'-dihydrothieno[2,3-b]naphtho-4',9'-dione)]-based cytotoxic agents: structure-activity relationship studies on the substituent at N4-position of the diketopiperazine domain

Spirostanol saponins of Allium porrum L

Structural studies on Hgr3 orphan receptor ligand prolactin-releasing peptide

Structure-Activity Relationship Studies, SPR Affinity Characterization, and Conformational Analysis of Peptides That Mimic the HNK-1 Carbohydrate Epitope.

Structure-Activity Relationships and Biological Characterization of a Novel, Potent, and Serum Stable C-X-C Chemokine Receptor Type 4 (CXCR4) Antagonist

Structure-activity relationship, conformational and biological studies of temporin L analogues

Structure?function Relationships and Conformational Properties of ?-MSH(6?13) Analogues with Candidacidal Activity

Structures and micelle locations of the nonlipidated and lipidated C-terminal membrane anchor of 2',3'-cyclic nucleotide-3'-phosphodiesterase

Synthesis and pharmacological evaluation of some 4-oxo-quinoline-2-carboxylic acid derivatives as anti-inflammatory and analgesic agents

Synthesis, in vitro, and in cell studies of a new series of [indoline-3,2'-thiazolidine]-based p53 modulators

The effect of d-amino acid substitution on the selectivity of temporin L towards target cells: identification of a potent anti-Candida peptide

The flavonoids of Allium neapolitanum

The flavonoids of Allium ursinum

Unraveling the Active Conformation of Urotensin II

Unraveling the active conformation of urotensin II.

Urantide conformation and interaction with the urotensin-II receptor.

Urokinase receptor derived peptides as potent inhibitors of the formyl peptide receptor type 1-triggered cell migration.

Urotensin-II receptor antagonists.

Urotensin-II receptor ligands. From agonist to antagonist activity

Urotensin-II receptor peptide agonists