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List of works by Julia Lorenzo

A carboxypeptidase inhibitor from the tick Rhipicephalus bursa: isolation, cDNA cloning, recombinant expression, and characterization

scientific article published on 23 November 2004

A novel quinoline molecular probe and the derived functionalized gold nanoparticles: sensing properties and cytotoxicity studies in MCF-7 human breast cancer cells

scientific article

A novel vanadyl complex with a polypyridyl DNA intercalator as ligand: a potential anti-protozoa and anti-tumor agent

scientific article

Amorphous Coordination Polymer Particles for Biomedicine

Amyloid formation by human carboxypeptidase D transthyretin-like domain under physiological conditions

scientific article published on 7 October 2014

Antitumor and antiparasitic activity of novel ruthenium compounds with polycyclic aromatic ligands

scientific article published on 09 June 2015

Biocatalytic synthesis, antimicrobial properties and toxicity studies of arginine derivative surfactants

scientific article published on 18 April 2015

Biochemical and MALDI-TOF Mass Spectrometric Characterization of a Novel Native and Recombinant Cystine Knot Miniprotein from Solanum tuberosum subsp. andigenum cv. Churqueña.

scientific article published on 28 February 2018

Biochemical characterization of a novel carboxypeptidase inhibitor from a variety of Andean potatoes

scientific article published on 28 October 2015

Biochemical characterization of the YBPCI miniprotein, the first carboxypeptidase inhibitor isolated from Yellow Bell Pepper (Capsicum annuum L). A novel contribution to the knowledge of miniproteins stability

scientific article

Biocompatible polydopamine-like particles for the removal of heavy metals at extremely low concentrations

scholarly article in RSC Advances, vol. 6 no. 46, 2016

C-terminomics screen for natural substrates of cytosolic carboxypeptidase 1 reveals processing of acidic protein C termini

scientific article published on 7 November 2014

Carboxyl group (-CO2 H) functionalized coordination polymer nanoparticles as efficient platforms for drug delivery

scientific article published on 5 October 2014

Carboxypeptidase inhibition by NvCI suppresses airway hyperreactivity in a mouse asthma model

scientific article published on 02 January 2021

Characterization of the substrate specificity of human carboxypeptidase A4 and implications for a role in extracellular peptide processing

scientific article

Characterization, Recombinant Production and Structure-Function Analysis of NvCI, A Picomolar Metallocarboxypeptidase Inhibitor from the Marine Snail Nerita versicolor

scientific article published on 29 August 2019

Conserved effects and altered trafficking of Cetuximab antibodies conjugated to gold nanoparticles with precise control of their number and orientation

scientific article published on 27 April 2017

Crystal structure and mechanism of human carboxypeptidase O: Insights into its specific activity for acidic residues.

scientific article published on 10 April 2018

Cytotoxicity studies of [PtCl2(H2bim)] (H2bim=2,2′-biimidazole): Study of its interaction with a small protein PCI (potato carboxypeptidase inhibitor)

article by Yolanda Parajó et al published February 2009 in Inorganica Chimica Acta

DNA binding studies of a series of cis-[Pt(Am)2X2] complexes (Am=inert amine, X=labile carboxylato ligand)

DNA interaction and antiproliferative behavior of the water soluble platinum supramolecular squares [(en)Pt(N-N)]4(NO3)8 (en=ethylenediamine, N-N=4,4'-bipyridine or 1,4-bis(4-pyridyl)tetrafluorobenzene).

scientific article published on 3 January 2007

DNA interaction and cytotoxicity studies of new ruthenium(II) cyclopentadienyl derivative complexes containing heteroaromatic ligands

article

Design and synthesis of new antitumor agents with the 1,7-epoxycyclononane framework. Study of their anticancer action mechanism by a model compound

scientific article published on 18 May 2018

Dual T1/T2 MRI contrast agent based on hybrid SPION@coordination polymer nanoparticles

scholarly article in RSC Advances, vol. 5 no. 105, 2015

Dual-Fluorescent Nanoscale Coordination Polymers via a Mixed-Ligand Synthetic Strategy and Their Use for Multichannel Imaging

Engineered nonviral nanocarriers for intracellular gene delivery applications

article

Evaluation of the metal-dependent cytotoxic behaviour of coordination compounds

scientific article published on 16 March 2018

Facile preparation of cationic gold nanoparticle-bioconjugates for cell penetration and nuclear targeting.

scientific article

Functional segregation and emerging role of cilia-related cytosolic carboxypeptidases (CCPs)

scientific article

Human pancreatic ribonuclease 1: expression and distribution in pancreatic adenocarcinoma

scientific article published on 01 September 2000

Identification of Carboxypeptidase Substrates by C-Terminal COFRADIC.

scientific article published in January 2017

Influence of PPh3 moiety in the anticancer activity of new organometallic ruthenium complexes

scientific article published on 15 March 2014

Influence of specific growth rate over the secretory expression of recombinant potato carboxypeptidase inhibitor in fed-batch cultures of Escherichia coli

article

Influence of the position of substituents in the cytotoxic activity of trans platinum complexes with hydroxymethyl pyridines

scientific article published on 19 October 2006

Inhibitors of aldehyde dehydrogenases of the 1A subfamily as putative anticancer agents: Kinetic characterization and effect on human cancer cells

scientific article published on 05 April 2019

Insights into the Two-Domain Architecture of the Metallocarboxypeptidase Inhibitor from theAscarisParasite Inferred from the Mechanism of Its Oxidative Folding

scientific article published in 2009

Integrated approach to produce a recombinant, His-tagged human α-galactosidase A in mammalian cells.

scientific article published on 25 May 2011

Internalization of cystatin C in human cell lines

scientific article

Iridium(III) coordination of N(6) modified adenine derivatives with aminoacid chains

scientific article published on 18 January 2020

Magnetic, fluorescent and hybrid nanoparticles: From synthesis to application in biosystems

scientific article published on 31 August 2019

Mechanism of action of potato carboxypeptidase inhibitor (PCI) as an EGF blocker

scientific article

New Cyclams and Their Copper(II) and Iron(III) Complexes: Synthesis and Potential Application as Anticancer Agents

scientific article published on 20 February 2019

New iron cyclopentadienyl complexes bearing different phosphane co -ligands: Structural factors vs. cytotoxicity

New iron(II) cyclopentadienyl derivative complexes: Synthesis and antitumor activity against human leukemia cancer cells

New palladium(II) and platinum(II) complexes with 9-aminoacridine: structures, luminiscence, theoretical calculations, and antitumor activity

scientific article

New palladium(II) and platinum(II) complexes with the model nucleobase 1-methylcytosine: antitumor activity and interactions with DNA.

scientific article published on October 2005

Nna1-like proteins are active metallocarboxypeptidases of a new and diverse M14 subfamily

scientific article

Non-toxic fluorescent alanine–fluorescein probe with green emission for dual colorimetric/fluorimetric sensing

article

Palladium(II) and platinum(II) organometallic complexes with the model nucleobase anions of thymine, uracil, and cytosine: antitumor activity and interactions with DNA of the platinum compounds

scientific article published on August 2006

Platinum complexes of diaminocarboxylic acids and their ethyl ester derivatives: the effect of the chelate ring size on antitumor activity and interactions with GMP and DNA.

scientific article published on September 2003

Proteome-derived peptide libraries to study the substrate specificity profiles of carboxypeptidases.

scientific article

Pt(IV)-based nanoscale coordination polymers: Antitumor activity, cellular uptake and interactions with nuclear DNA

Relaxometry studies of a highly stable nanoscale metal-organic framework made of Cu(II), Gd(III), and the macrocyclic DOTP.

scientific article published on 14 November 2013

Role of kinetic intermediates in the folding of leech carboxypeptidase inhibitor

scientific article published on 28 June 2004

Screening organometallic binuclear thiosemicarbazone ruthenium complexes as potential anti-tumour agents: cytotoxic activity and human serum albumin binding mechanism

scientific article published on May 2013

Secondary binding site of the potato carboxypeptidase inhibitor. Contribution to its structure, folding, and biological properties

scientific article published in June 2004

Silica Coated Iron/Iron Oxide Nanoparticles as a Nano-Platform for T2 Weighted Magnetic Resonance Imaging

scientific article published on 17 December 2019

Squaramide-Based Pt(II) Complexes as Potential Oxygen-Regulated Light-Triggered Photocages

scientific article published on 29 November 2018

Structure-function analysis of the short splicing variant carboxypeptidase encoded by Drosophila melanogaster silver

scientific article

Studies of the Antiproliferative Activity of Ruthenium (II) Cyclopentadienyl-Derived Complexes with Nitrogen Coordinated Ligands.

scientific article published on 20 June 2010

Study and Preparation of Multifunctional Poly(L-Lysine)@Hyaluronic Acid Nanopolyplexes for the Effective Delivery of Tumor Suppressive MiR-34a into Triple-Negative Breast Cancer Cells

scientific article published on 24 November 2020

Study by HPLC-MS of the interaction of platinum antitumor complexes with potato carboxypeptidase inhibitor (PCI).

scientific article

Studying the reactivity of "old" Cu(II) complexes for "novel" anticancer purposes

scientific article published on 18 March 2019

Substrate Specificity and Structural Modeling of Human Carboxypeptidase Z: A Unique Protease with a Frizzled-Like Domain

scientific article published on 18 November 2020

Substrate specificity of human metallocarboxypeptidase D: Comparison of the two active carboxypeptidase domains.

scientific article published on 13 November 2017

Sustainable synthesis of luminescent CdTe quantum dots coated with modified silica mesoporous nanoparticles: Towards new protein scavengers and smart drug delivery carriers

Synthesis and Structural/Functional Characterization of Selective M14 Metallocarboxypeptidase Inhibitors Based on Phosphinic Pseudopeptide Scaffold: Implications on the Design of Specific Optical Probes

scientific article published on 13 February 2019

Synthesis of Co–Organosilane–Au Nanocomposites via a Controlled Interphasic Reduction

Synthesis of functionalized fluorescent silver nanoparticles and their toxicological effect in aquatic environments (Goldfish) and HEPG2 cells

scientific article published on 05 December 2013

Synthesis, Culture Medium Stability, and In Vitro and In Vivo Zebrafish Embryo Toxicity of Metal-Organic Framework Nanoparticles

article

Synthesis, DNA interaction and cytotoxicity studies of cis-{[1, 2-bis(aminomethyl)cyclohexane]dihalo}platinum(II) complexes

scientific article published on 8 January 2008

Synthesis, biological evaluation and SAR studies of novel bicyclic antitumor platinum(IV) complexes

scientific article published on 21 June 2014

Synthesis, characterization and antiproliferative studies of the enantiomers of cis-[(1,2-camphordiamine)dichloro]platinum(II) complexes.

scientific article published on 13 November 2007

Synthesis, characterization and biological activity of trans-platinum(II) and trans-platinum(IV) complexes with 4-hydroxymethylpyridine.

scientific article

The cytosolic carboxypeptidases CCP2 and CCP3 catalyze posttranslational removal of acidic amino acids

scientific article

The molecular shape and the field similarities as criteria to interpret SAR studies for fragment-based design of platinum(IV) anticancer agents. Correlation of physicochemical properties with cytotoxicity

scientific article published on 18 August 2016

The novel structure of a cytosolic M14 metallocarboxypeptidase (CCP) from Pseudomonas aeruginosa: a model for mammalian CCPs

scientific article

The three-dimensional structures of tick carboxypeptidase inhibitor in complex with A/B carboxypeptidases reveal a novel double-headed binding mode.

scientific article

Vanadium polypyridyl compounds as potential antiparasitic and antitumoral agents: new achievements

scientific article published on 12 November 2010

Vanadium(IV) and copper(II) complexes of salicylaldimines and aromatic heterocycles: Cytotoxicity, DNA binding and DNA cleavage properties

scientific article published on 08 March 2015

Versatile iron-catechol-based nanoscale coordination polymers with antiretroviral ligand functionalization and their use as efficient carriers in HIV/AIDS therapy

scientific article published on 01 December 2018

Water-soluble platinum(II) complexes of diamine chelating ligands bearing amino-acid type substituents: the effect of the linked amino acid and the diamine chelate ring size on antitumor activity, and interactions with 5'-GMP and DNA.

scientific article

[RuCl2(η6-p-cymene)(P*)] and [RuCl2(κ-P*-η6-arene)] Complexes Containing P-Stereogenic Phosphines. Activity in Transfer Hydrogenation and Interactions with DNA

pH-Responsive Relaxometric Behaviour of Coordination Polymer Nanoparticles Made of a Stable Macrocyclic Gadolinium Chelate

scientific article

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