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List of works by Dean A. Lee

A Novel Method for Assessment of Natural Killer Cell Cytotoxicity Using Image Cytometry

scientific article (publication date: 2015)

A high throughput microelectroporation device to introduce a chimeric antigen receptor to redirect the specificity of human T cells

scientific article

Acquisition, preparation, and functional assessment of human NK cells for adoptive immunotherapy

scientific article published on 01 January 2010

Activated peripheral T lymphocytes undergo apoptosis when cultured with monocytes activated by HLA class II ligation

scientific article published on 01 October 2003

Activating and propagating polyclonal gamma delta T cells with broad specificity for malignancies

scientific article

Advances in clinical NK cell studies: Donor selection, manufacturing and quality control

scientific article published on 11 November 2015

Aerosol interleukin-2 induces natural killer cell proliferation in the lung and combination therapy improves the survival of mice with osteosarcoma lung metastasis.

scientific article

Antibody Fc engineering improves frequency and promotes kinetic boosting of serial killing mediated by NK cells.

scientific article

Antigen presenting cell-mediated expansion of human umbilical cord blood yields log-scale expansion of natural killer cells with anti-myeloma activity.

scientific article

Autologous bone marrow mononuclear cell therapy for severe traumatic brain injury in children

scientific article published in March 2011

Autologous bone marrow mononuclear cells reduce therapeutic intensity for severe traumatic brain injury in children

scientific article

Bioengineering T cells to target carbohydrate to treat opportunistic fungal infection.

scientific article

C/EBPbeta suppression by interruption of CUGBP1 resulting from a complex rearrangement of MLL.

scientific article published in September 2007

Cellular engineering and therapy in combination with cord blood allografting in pediatric recipients

scientific article published on 14 September 2015

Cellular therapy: Adoptive immunotherapy with expanded natural killer cells

scientific article published on 01 July 2019

Chimeric antigen receptor (CAR)-specific monoclonal antibody to detect CD19-specific T cells in clinical trials

scientific article (publication date: 2013)

Chromatin remodelling at the topoisomerase II-beta promoter is associated with enhanced sensitivity to etoposide in human neuroblastoma cell lines

scientific article published on October 2010

Clinical-scale derivation of natural killer cells from human pluripotent stem cells for cancer therapy.

scientific article published on 20 March 2013

Combining CD19 redirection and alloanergization to generate tumor-specific human T cells for allogeneic cell therapy of B-cell malignancies.

scientific article

Cytotoxicity of CD56-positive lymphocytes against autologous B-cell precursor acute lymphoblastic leukemia cells

scientific article published on 19 August 2014

Decitabine has a biphasic effect on natural killer cell viability, phenotype, and function under proliferative conditions

scientific article published on 16 January 2013

Defining and managing career challenges for mid-career and senior stage pediatric hematologist/oncologists

scientific article published in December 2010

EBV+ lymphoproliferative disease following prolonged chemotherapy for refractory LCH.

scientific article published in March 2008

Engineering lymph node homing of ex vivo-expanded human natural killer cells via trogocytosis of the chemokine receptor CCR7.

scientific article

Evaluation of serum-free media formulations in feeder cell-stimulated expansion of natural killer cells

scientific article published on 08 April 2020

Expansion, Purification, and Functional Assessment of Human Peripheral Blood NK Cells ⬇️

scientific article published on 02 February 2011

Expression of carcinoma, apoptosis, and cell-death-related genes are determinants for sensitivity of pediatric cancer cell lines to lysis by natural killer cells

scientific article published on 15 July 2019

Fenretinide sensitizes multidrug-resistant human neuroblastoma cells to antibody-independent and ch14.18-mediated NK cell cytotoxicity.

scientific article

Granulocytic sarcoma presenting as pneumonia in a child with t(8;21) acute myelogenous leukemia: diagnosis by fluorescent in situ hybridization

scientific article published on July 2004

HIV false positivity after hepatitis B vaccination

scientific article published in April 1992

Haploidentical Hematopoietic Stem Cell Transplantation as a Platform for Post-Transplantation Cellular Therapy

scientific article

Haploidentical Natural Killer Cells Infused before Allogeneic Stem Cell Transplantation for Myeloid Malignancies: A Phase I Trial

scientific article published on 15 April 2016

IL-12 and IL-27 sequential gene therapy via intramuscular electroporation delivery for eliminating distal aggressive tumors.

scientific article

Identifying candidate allogeneic NK-cell donors for hematopoietic stem-cell transplantation based on functional phenotype.

scientific article

Imaging of Sleeping Beauty-Modified CD19-Specific T Cells Expressing HSV1-Thymidine Kinase by Positron Emission Tomography

scientific article published on 31 May 2016

Immune profiles of desmoplastic small round cell tumor and synovial sarcoma suggest different immunotherapeutic susceptibility upfront compared to relapse specimens

scientific article published on 17 July 2018

In Vitro and In Vivo Antitumor Effect of Anti-CD33 Chimeric Receptor-Expressing EBV-CTL against CD33 Acute Myeloid Leukemia

scientific article published on 5 January 2012

Infusing CD19-directed T cells to augment disease control in patients undergoing autologous hematopoietic stem-cell transplantation for advanced B-lymphoid malignancies.

scientific article

Investigation of donor KIR content and matching in children undergoing hematopoietic cell transplantation for acute leukemia

scientific article published on 01 April 2020

Is there an expiration date for a cord blood unit in storage?

scientific article

Membrane-bound IL-21 promotes sustained ex vivo proliferation of human natural killer cells

scientific article

Mentoring in pediatric oncology: a report from the Children's Oncology Group Young Investigator Committee

scientific article published on August 2013

NK cell therapy: targeting disease relapse after hematopoietic stem cell transplantation

scientific article

Natural killer cell adoptive immunotherapy: Coming of age.

scientific article published on 13 February 2016

Natural killer cell therapy and aerosol interleukin-2 for the treatment of osteosarcoma lung metastasis.

scientific article

Natural killer cells for osteosarcoma.

scientific article

Natural killer cells stimulated with PM21 particles expand and biodistribute in vivo: Clinical implications for cancer treatment.

scientific article published on May 2016

New insights to the MLL recombinome of acute leukemias

scientific article

Phase I study of cord blood-derived natural killer cells combined with autologous stem cell transplantation in multiple myeloma

scientific article

Phase I trials using Sleeping Beauty to generate CD19-specific CAR T cells

scientific article published on 02 August 2016

Recurrent Stimulation of Natural Killer Cell Clones with K562 Expressing Membrane-Bound Interleukin-21 Affects Their Phenotype, Interferon-γ Production, and Lifespan

scientific article published on 21 January 2019

Redirecting T-Cell Specificity to EGFR Using mRNA to Self-limit Expression of Chimeric Antigen Receptor

scientific article published in June 2016

Repression of GSK3 restores NK cell cytotoxicity in AML patients

scientific article published on 4 April 2016

Reprogramming CD19-specific T cells with IL-21 signaling can improve adoptive immunotherapy of B-lineage malignancies.

scientific article

Results of a 2-arm, phase 2 clinical trial using post-transplantation cyclophosphamide for the prevention of graft-versus-host disease in haploidentical donor and mismatched unrelated donor hematopoietic stem cell transplantation

scientific article published on 12 July 2016

Rotavirus vaccines

scientific article published on 01 April 2006

Similar transplantation outcomes for acute myeloid leukemia and myelodysplastic syndrome patients with haploidentical versus 10/10 human leukocyte antigen-matched unrelated and related donors.

scientific article

Strategies for combining immunotherapy with radiation for anticancer therapy

scientific article (publication date: 2015)

T cells redirected to EphA2 for the immunotherapy of glioblastoma

scientific article

The hyperactive Sleeping Beauty transposase SB100X improves the genetic modification of T cells to express a chimeric antigen receptor

scientific article

The narrow-spectrum HDAC inhibitor entinostat enhances NKG2D expression without NK cell toxicity, leading to enhanced recognition of cancer cells

scientific article

The off-target effects of nonspecific NK cells

scientific article published in January 2015

Toward eliminating HLA class I expression to generate universal cells from allogeneic donors

scientific article published on 05 June 2013

Trace Evidence: Identifying Natural Cancer Killers After the Crime.

scientific article published on 24 September 2015

Transcription of the activating receptor NKG2D in natural killer cells is regulated by STAT3 tyrosine phosphorylation.

scientific article

Trastuzumab upregulates expression of HLA-ABC and T cell costimulatory molecules through engagement of natural killer cells and stimulation of IFNγ secretion.

scientific article published on 29 October 2015

Tumor lysing genetically engineered T cells loaded with multi-modal imaging agents

scientific article published on 28 March 2014

Tumor-specific human CD4+ regulatory T cells and their ligands: implications for immunotherapy

scientific article published in January 2004

Tuning Sensitivity of CAR to EGFR Density Limits Recognition of Normal Tissue While Maintaining Potent Antitumor Activity

scientific article

Universal artificial antigen presenting cells to selectively propagate T cells expressing chimeric antigen receptor independent of specificity

scientific article

Venous Thromboembolism in Pediatric Hematopoietic Cell Transplant: A Multicenter Cohort Study.

scientific article

piggyBac transposon/transposase system to generate CD19-specific T cells for the treatment of B-lineage malignancies

scientific article

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