List of works - Sabrina Dallavalle

3-Arylidene-N-hydroxyoxindoles: A New Class of Compounds Endowed with Antitumor Activity

scientific article published on 17 June 2016

4-Quinolone fused heterocyclic ring systems by intramolecular reactions of 4-quinolone-2-carboxamides

7-Azaindole-1-carboxamides as a new class of PARP-1 inhibitors.

scientific article published on 22 December 2013

A New Azoxyalkene from a Strain of anActinomadura-Like Fungus

scientific article published on 01 June 2003

A Novel Enhancement of Nano Structure by Organic Acid Dopants in Emulsion Polymerization of Poly(o-toluidine)

A Synthetic Approach to Sporotricale Methylether

A derivative of the natural compound kakuol affects DNA relaxation of topoisomerase IB inhibiting the cleavage reaction.

scientific article published on 19 December 2012

A new 3,4-seco-lupane derivative from Lasianthus gardneri

scientific article

A new group of oxime carbamates as reversible inhibitors of fatty acid amide hydrolase.

scientific article published on 15 June 2010

A new synthesis of isoaurones: cytotoxic activity of compounds related to the alleged structure of isoaurostatin

scientific article

A new synthesis of the cytotoxic alkaloid Luotonine A

A novel atypical retinoid endowed with proapoptotic and antitumor activity

scientific article published in March 2003

A predictive active site model for the cyclohexanone monooxygenase catalyzed oxidation of sulfides to chiral sulfoxides

article

Absolute Configuration of Sporotricale and Structure of 6-Hydroxysporotricale

scientific article published on 01 December 2006

Acremines A–F, novel secondary metabolites produced by a strain of an endophytic Acremonium, isolated from sporangiophores of Plasmopara viticola in grapevine leaves

Acremines H–N, novel prenylated polyketide metabolites produced by a strain of Acremonium byssoides ⬇️

An unusual dimer of camptothecin-7-aldehyde

Antibacterial and antifungal activities of 2,3-pyrrolidinedione derivatives against oral pathogens

scientific article published on 04 February 2016

Antimicrobial activity of resveratrol-derived monomers and dimers against foodborne pathogens

scientific article published on 20 December 2019

Antitumor Activity of the Retinoid-Related Molecules (E)-3-(4'-Hydroxy-3'-adamantylbiphenyl-4-yl)acrylic Acid (ST1926) and 6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalene Carboxylic Acid (CD437) in F9 Teratocarcinoma: Role of Retinoic Acid Receptor

scientific article published on 20 June 2006

Apoptosis-mediated anticancer activity in prostate cancer cells of a chestnut honey (Castanea sativa L.) quinoline-pyrrolidine gamma-lactam alkaloid

scientific article published on 04 May 2021

Asymmetric oxidation of sulfides by cyclohexanone monooxygenase

Autopoietic Self-Reproduction of Chiral Fatty Acid Vesicles

scientific article published in 1997

Biphenyl-4-yl-acrylohydroxamic acids: Identification of a novel indolyl-substituted HDAC inhibitor with antitumor activity.

scientific article published on 3 February 2016

Camptothecin and Analogs: Structure and Synthetic Efforts

Conducting Polyaniline is an Efficient Catalyst for Synthesis of 3,4-dihydropyrimidin-2-(1H)-one Derivative Under Solvent-Free Conditions

Corrigendum to “Natural and semisynthetic azaphilones as a new scaffold for Hsp90 inhibitors” [Bioorg. Med. Chem. 18 (2010) 6031–6043]

scholarly article published in Bioorganic & Medicinal Chemistry

Current status and perspectives in the development of camptothecins

scientific article (publication date: 2002)

Design, modeling, synthesis and biological activity evaluation of camptothecin-linked platinum anticancer agents

scientific article published on March 2013

Design, synthesis, and evaluation of biphenyl-4-yl-acrylohydroxamic acid derivatives as histone deacetylase (HDAC) inhibitors

scientific article

Development and therapeutic impact of HDAC6-selective inhibitors

scientific article published on 21 June 2012

Discovery of a Novel, Isothiazolonaphthoquinone-Based Small Molecule Activator of FOXO Nuclear-Cytoplasmic Shuttling

scientific article published in 2016

Dual-active antifungal agents containing strobilurin and SDHI-based pharmacophores

scientific article published on 06 August 2019

Efficient Synthesis of 3,7-Diaryl-1,4-dihydro[1,2,4]triazolo[5,1-c][1,2,4]triazines

article published in 2012

Embelin as Lead Compound for New Neuroserpin Polymerization Inhibitors

scientific article published on 11 July 2020

Enantioselective total synthesis and absolute configuration of the alleged structure of crassinervic acid

Enol carbamates as inhibitors of fatty acid amide hydrolase (FAAH) endowed with high selectivity for FAAH over the other targets of the endocannabinoid system

scientific article published in March 2010

First total synthesis of cyrmenin B1.

scientific article published in January 2009

First total synthesis of the antifungal antibiotic thiobutacin

First total synthesis of topopyrone C

Hybrid topoisomerase I and HDAC inhibitors as dual action anticancer agents

scientific article published in PLoS ONE

Identification of a novel arylpiperazine scaffold for fatty acid amide hydrolase inhibition with improved drug disposition properties

scientific article published on 22 November 2012

Identification of new scaffolds with anti-tumor action toward human glioblastoma cells

Improved Synthesis of Farinomalein and Its Analogs

Influence of the adamantyl moiety on the activity of biphenylacrylohydroxamic acid-based HDAC inhibitors

scientific article published on 8 April 2014

Interaction between double helix DNA fragments and a new topopyrone acting as human topoisomerase I poison

scientific article

Intramolecular Friedel-Crafts Reaction of Indoles with Carbonyl Groups: A Simple Synthesis of 3- and 4-Substituted β-Carbolin-1-ones

Intramolecular N-acyliminium ion versus Friedel–Crafts cyclization onto 3-indoles: synthesis of the novel rings pyrrolizino[2,1-b]indole and homologues

Investigation on the ZBG-functionality of phenyl-4-yl-acrylohydroxamic acid derivatives as histone deacetylase inhibitors

scientific article published on 5 September 2015

Isoxazolo(aza)naphthoquinones: a new class of cytotoxic Hsp90 inhibitors

scientific article published on 28 March 2012

Mode of binding of camptothecins to double helix oligonucleotides

scientific article

Natural Compound-derived Cytochrome bc1 Complex Inhibitors as Antifungal Agents

scientific article published on 07 October 2020

Natural Products as Sources of New Fungicides: Synthesis and Antifungal Activity of Zopfiellin Analogues

scientific article published on 20 February 2012

Natural and semisynthetic azaphilones as a new scaffold for Hsp90 inhibitors

scientific article published on July 2010

New retinoid derivatives as back-ups of Adarotene

scientific article

Novel 7-oxyiminomethyl derivatives of camptothecin with potent in vitro and in vivo antitumor activity

scientific article

Novel 7-substituted camptothecins with potent antitumor activity

scientific article

Novel PARP-1 inhibitors based on a 2-propanoyl-3H-quinazolin-4-one scaffold

scientific article

Novel cytotoxic 7-iminomethyl and 7-aminomethyl derivatives of camptothecin.

scientific article

Novel tumor-targeted RGD peptide-camptothecin conjugates: synthesis and biological evaluation

scientific article

Optimized synthesis and enhanced efficacy of novel triplex-forming camptothecin derivatives based on gimatecan

scientific article

Perspectives in camptothecin development

article

Perspectives in the development of hybrid bifunctional antitumour agents

scientific article published on 11 June 2015

Polyindole-ZnO Nanocomposite: Synthesis, Characterization and Heterogeneous Catalyst for the 3,4-Dihydropyrimidinone Synthesis under Solvent-free Conditions

Preclinical efficacy of ST1976, a novel camptothecin analog of the 7-oxyiminomethyl series

scientific article published on 9 November 2006

Preclinical profile of antitumor activity of a novel hydrophilic camptothecin, ST1968.

scientific article

Promysalin is a salicylate-containing antimicrobial with a cell-membrane-disrupting mechanism of action on Gram-positive bacteria

scientific article published on 18 August 2017

Protoilludane sesquiterpenoids as scaffold structures for new antimicrobials against Mannheimia haemolytica

scientific article published on 24 October 2012

Putative SARS-CoV-2 Mpro Inhibitors from an In-House Library of Natural and Nature-Inspired Products: A Virtual Screening and Molecular Docking Study

scientific article published on 17 August 2020

Screening of the chemical composition and bioactivity of Waldheimia glabra (Decne.) Regel essential oil.

scientific article published on 15 October 2015

Sequence-specific targeting of IGF-I and IGF-IR genes by camptothecins

scientific article

Short Synthesis of Cytotoxic 4‐Arylcoumarins

Sodium 4-Carboxymethoxyimino-(4-HPR) a Novel Water-Soluble Derivative of 4-Oxo-4-HPR Endowed with In Vivo Anticancer Activity on Solid Tumors

scientific article

Structure and absolute configuration of new acidic metabolites from Stachys ehrenbergii

article published in 2011

Study of Biological Activity of Conducting Poly(N-Ethylaniline) Nanoparticles Doped with Organic Acid

Synthesis and Antifungal Activity of 2-Hydroxy-4,5-methylenedioxyaryl Ketones as Analogues of Kakuol

scientific article published on 01 April 2010

Synthesis and RET protein kinase inhibitory activity of 3-arylureidobenzylidene-indolin-2-ones

scientific article published on 30 April 2007

Synthesis and StructureActivity Relationships of Antifungal Crassinervic Acid Analogs

scientific article published on 01 January 2012

Synthesis and antifungal activity of a series of N-substituted [2-(2,4-dichlorophenyl)-3-(1,2,4-triazol-1-yl)]propylamines

scientific article published in October 2007

Synthesis and characterization of Polyindole and its catalytic performance study as a heterogeneous catalyst

Synthesis and cytotoxic activity of a new series of topoisomerase I inhibitors

scientific article published on 25 December 2007

Synthesis and cytotoxic activity of new 9-substituted camptothecins

scientific article published on 10 April 2008

Synthesis and cytotoxic activity of polyamine analogues of camptothecin

scientific article published on August 2006

Synthesis and cytotoxic activity of substituted 7-aryliminomethyl derivatives of camptothecin

scientific article published on June 2004

Synthesis and cytotoxic activity of substituted luotonin A derivatives

scientific article

Synthesis and evaluation of structural requirements for antifungal activity of cyrmenin B1 analogues

Synthesis and structure-activity relationships of a new series of retinoid-related biphenyl-4-ylacrylic acids endowed with antiproliferative and proapoptotic activity

scientific article published on July 2005

Synthesis and structure-activity relationships of new antiproliferative and proapoptotic retinoid-related biphenyl-4-yl-acrylic acids

scientific article

Synthesis and topoisomerase I inhibitory activity of a novel diazaindeno[2,1-b]phenanthrene analogue of Lamellarin D.

scientific article

Synthesis of (+)-Spirolaxine Methyl Ether

scientific article published on 01 August 2006

Synthesis of 5,6-dihydro-4H -benzo[d ]isoxazol-7-one and 5,6-dihydro-4H -isoxazolo[5,4-c ]pyridin-7-one Derivatives as Potential Hsp90 Inhibitors

scientific article published on 30 April 2015

Synthesis of a leopolic acid-inspired tetramic acid with antimicrobial activity against multidrug-resistant bacteria

scientific article published on 24 September 2018

Synthesis of chiral benzyl alkyl sulfoxides by cyclohexanone monooxygenase from Acinetobacter NCIB 9871

Synthesis of natural maleimides farinomaleins C–E and evaluation of their antifungal activity

Synthesis of new cytotoxic E-ring modified camptothecins

Synthesis of photoactivable inhibitors of osteoclast vacuolar ATPase

scientific article published on May 2003

Synthesis of the Tripeptide Antibiotic Resormycin

Synthesis, modeling, and RET protein kinase inhibitory activity of 3- and 4-substituted beta-carbolin-1-ones

scientific article published on December 2008

Synthetic retinoids as potential antitumour agents

The antiproliferative and proapoptotic effects of cladosporols A and B are related to their different binding mode as PPARγ ligands

scientific article published on 16 March 2016

Total Synthesis of Berkeleyamide A and its 10-epi Isomer

Total synthesis of leopolic acid A, a natural 2,3-pyrrolidinedione with antimicrobial activity

scientific article published on 29 July 2016

Total synthesis of the natural product benzo[j]fluoranthene-4,9-diol: an approach to the synthesis of oxygenated benzo[j]fluoranthenes.

scientific article published on 11 October 2013

Total synthesis of the salicyldehydroproline-containing antibiotic promysalin

Ultrasound Synthesis of Polyindole–TiO2 Nanocomposite and Evaluation of Antibacterial Activity

Water-soluble derivatives of 4-oxo-N-(4-hydroxyphenyl) retinamide: synthesis and biological activity.

scientific article published on 2 May 2016

List of works by Sabrina Dallavalle

3-Arylidene-N-hydroxyoxindoles: A New Class of Compounds Endowed with Antitumor Activity

4-Quinolone fused heterocyclic ring systems by intramolecular reactions of 4-quinolone-2-carboxamides

7-Azaindole-1-carboxamides as a new class of PARP-1 inhibitors.

A New Azoxyalkene from a Strain of anActinomadura-Like Fungus

A Novel Enhancement of Nano Structure by Organic Acid Dopants in Emulsion Polymerization of Poly(o-toluidine)

A Synthetic Approach to Sporotricale Methylether

A derivative of the natural compound kakuol affects DNA relaxation of topoisomerase IB inhibiting the cleavage reaction.

A new 3,4-seco-lupane derivative from Lasianthus gardneri

A new group of oxime carbamates as reversible inhibitors of fatty acid amide hydrolase.

A new synthesis of isoaurones: cytotoxic activity of compounds related to the alleged structure of isoaurostatin

A new synthesis of the cytotoxic alkaloid Luotonine A

A novel atypical retinoid endowed with proapoptotic and antitumor activity

A predictive active site model for the cyclohexanone monooxygenase catalyzed oxidation of sulfides to chiral sulfoxides

Absolute Configuration of Sporotricale and Structure of 6-Hydroxysporotricale

Acremines A–F, novel secondary metabolites produced by a strain of an endophytic Acremonium, isolated from sporangiophores of Plasmopara viticola in grapevine leaves

Acremines H–N, novel prenylated polyketide metabolites produced by a strain of Acremonium byssoides ⬇️

An unusual dimer of camptothecin-7-aldehyde

Antibacterial and antifungal activities of 2,3-pyrrolidinedione derivatives against oral pathogens

Antimicrobial activity of resveratrol-derived monomers and dimers against foodborne pathogens

Antitumor Activity of the Retinoid-Related Molecules (E)-3-(4'-Hydroxy-3'-adamantylbiphenyl-4-yl)acrylic Acid (ST1926) and 6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalene Carboxylic Acid (CD437) in F9 Teratocarcinoma: Role of Retinoic Acid Receptor

Apoptosis-mediated anticancer activity in prostate cancer cells of a chestnut honey (Castanea sativa L.) quinoline-pyrrolidine gamma-lactam alkaloid

Asymmetric oxidation of sulfides by cyclohexanone monooxygenase

Autopoietic Self-Reproduction of Chiral Fatty Acid Vesicles

Biphenyl-4-yl-acrylohydroxamic acids: Identification of a novel indolyl-substituted HDAC inhibitor with antitumor activity.

Camptothecin and Analogs: Structure and Synthetic Efforts

Conducting Polyaniline is an Efficient Catalyst for Synthesis of 3,4-dihydropyrimidin-2-(1H)-one Derivative Under Solvent-Free Conditions

Corrigendum to “Natural and semisynthetic azaphilones as a new scaffold for Hsp90 inhibitors” [Bioorg. Med. Chem. 18 (2010) 6031–6043]

Current status and perspectives in the development of camptothecins

Design, modeling, synthesis and biological activity evaluation of camptothecin-linked platinum anticancer agents

Design, synthesis, and evaluation of biphenyl-4-yl-acrylohydroxamic acid derivatives as histone deacetylase (HDAC) inhibitors

Development and therapeutic impact of HDAC6-selective inhibitors

Discovery of a Novel, Isothiazolonaphthoquinone-Based Small Molecule Activator of FOXO Nuclear-Cytoplasmic Shuttling

Dual-active antifungal agents containing strobilurin and SDHI-based pharmacophores

Efficient Synthesis of 3,7-Diaryl-1,4-dihydro[1,2,4]triazolo[5,1-c][1,2,4]triazines

Embelin as Lead Compound for New Neuroserpin Polymerization Inhibitors

Enantioselective total synthesis and absolute configuration of the alleged structure of crassinervic acid

Enol carbamates as inhibitors of fatty acid amide hydrolase (FAAH) endowed with high selectivity for FAAH over the other targets of the endocannabinoid system

First total synthesis of cyrmenin B1.

First total synthesis of the antifungal antibiotic thiobutacin

First total synthesis of topopyrone C

Hybrid topoisomerase I and HDAC inhibitors as dual action anticancer agents

Identification of a novel arylpiperazine scaffold for fatty acid amide hydrolase inhibition with improved drug disposition properties

Identification of new scaffolds with anti-tumor action toward human glioblastoma cells

Improved Synthesis of Farinomalein and Its Analogs

Influence of the adamantyl moiety on the activity of biphenylacrylohydroxamic acid-based HDAC inhibitors

Interaction between double helix DNA fragments and a new topopyrone acting as human topoisomerase I poison

Intramolecular Friedel-Crafts Reaction of Indoles with Carbonyl Groups: A Simple Synthesis of 3- and 4-Substituted β-Carbolin-1-ones

Intramolecular N-acyliminium ion versus Friedel–Crafts cyclization onto 3-indoles: synthesis of the novel rings pyrrolizino[2,1-b]indole and homologues

Investigation on the ZBG-functionality of phenyl-4-yl-acrylohydroxamic acid derivatives as histone deacetylase inhibitors

Isoxazolo(aza)naphthoquinones: a new class of cytotoxic Hsp90 inhibitors

Mode of binding of camptothecins to double helix oligonucleotides

Natural Compound-derived Cytochrome bc1 Complex Inhibitors as Antifungal Agents

Natural Products as Sources of New Fungicides: Synthesis and Antifungal Activity of Zopfiellin Analogues

Natural and semisynthetic azaphilones as a new scaffold for Hsp90 inhibitors

New retinoid derivatives as back-ups of Adarotene

Novel 7-oxyiminomethyl derivatives of camptothecin with potent in vitro and in vivo antitumor activity

Novel 7-substituted camptothecins with potent antitumor activity

Novel PARP-1 inhibitors based on a 2-propanoyl-3H-quinazolin-4-one scaffold

Novel cytotoxic 7-iminomethyl and 7-aminomethyl derivatives of camptothecin.

Novel tumor-targeted RGD peptide-camptothecin conjugates: synthesis and biological evaluation

Optimized synthesis and enhanced efficacy of novel triplex-forming camptothecin derivatives based on gimatecan

Perspectives in camptothecin development

Perspectives in the development of hybrid bifunctional antitumour agents

Polyindole-ZnO Nanocomposite: Synthesis, Characterization and Heterogeneous Catalyst for the 3,4-Dihydropyrimidinone Synthesis under Solvent-free Conditions

Preclinical efficacy of ST1976, a novel camptothecin analog of the 7-oxyiminomethyl series

Preclinical profile of antitumor activity of a novel hydrophilic camptothecin, ST1968.

Promysalin is a salicylate-containing antimicrobial with a cell-membrane-disrupting mechanism of action on Gram-positive bacteria

Protoilludane sesquiterpenoids as scaffold structures for new antimicrobials against Mannheimia haemolytica

Putative SARS-CoV-2 Mpro Inhibitors from an In-House Library of Natural and Nature-Inspired Products: A Virtual Screening and Molecular Docking Study

Screening of the chemical composition and bioactivity of Waldheimia glabra (Decne.) Regel essential oil.

Sequence-specific targeting of IGF-I and IGF-IR genes by camptothecins

Short Synthesis of Cytotoxic 4‐Arylcoumarins

Sodium 4-Carboxymethoxyimino-(4-HPR) a Novel Water-Soluble Derivative of 4-Oxo-4-HPR Endowed with In Vivo Anticancer Activity on Solid Tumors

Structure and absolute configuration of new acidic metabolites from Stachys ehrenbergii

Study of Biological Activity of Conducting Poly(N-Ethylaniline) Nanoparticles Doped with Organic Acid

Synthesis and Antifungal Activity of 2-Hydroxy-4,5-methylenedioxyaryl Ketones as Analogues of Kakuol

Synthesis and RET protein kinase inhibitory activity of 3-arylureidobenzylidene-indolin-2-ones

Synthesis and StructureActivity Relationships of Antifungal Crassinervic Acid Analogs

Synthesis and antifungal activity of a series of N-substituted [2-(2,4-dichlorophenyl)-3-(1,2,4-triazol-1-yl)]propylamines