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List of works by Edgar Julián Paredes Gamero

17β-Estradiol and steady-state concentrations of H2O2: antiapoptotic effect in endometrial cells from patients with endometriosis.

scientific article published on 14 February 2013

4-Deoxyraputindole C induces cell death and cell cycle arrest in tumor cell lines

scientific article published on 07 December 2018

4′-Hydroxy-6,7-methylenedioxy-3-methoxyflavone: A novel flavonoid from Dulacia egleri with potential inhibitory activity against cathepsins B and L

scientific article published on 13 August 2018

A heparin mimetic isolated from a marine shrimp suppresses neovascularization.

scientific article

A high-fat diet increases interleukin-3 and granulocyte colony-stimulating factor production by bone marrow cells and triggers bone marrow hyperplasia and neutrophilia in Wistar rats

scientific article published in April 2013

A synthetic fragment of leptin increase hematopoietic stem cell population and improve its engraftment ability.

scientific article published in July 2015

Activation of P2Y1 receptor triggers two calcium signaling pathways in bone marrow erythroblasts

scientific article published on 20 February 2006

Activation of the low molecular weight protein tyrosine phosphatase in keratinocytes exposed to hyperosmotic stress

scientific article published on 17 March 2015

Altered Cellular Homeostasis in Murine MPS I Fibroblasts: Evidence of Cell-Specific Physiopathology

scientific article

Angiotensin II binding to angiotensin I-converting enzyme triggers calcium signaling.

scientific article published on 21 March 2011

Anti-Cancer Phytometabolites Targeting Cancer Stem Cells

scientific article

Antimicrobial, antioxidant and cytotoxic activities of propolis from Melipona orbignyi (Hymenoptera, Apidae).

scientific article published on 9 January 2014

Antioxidant and cytotoxic activity of hydroethanolic extract from Jacaranda decurrens leaves

scientific article

Antioxidant and cytotoxic activity of propolis of Plebeia droryana and Apis mellifera (Hymenoptera, Apidae) from the Brazilian Cerrado biome

scientific article published on 12 September 2017

Antioxidant, Cytotoxic, and Toxic Activities of Propolis from Two Native Bees in Brazil: Scaptotrigona depilis and Melipona quadrifasciata anthidioides

scientific article published on 9 March 2017

Antitumor Potential of S-Nitrosothiol-Containing Polymeric Nanoparticles against Melanoma

scientific article

Assessment of fatty infiltration of the multifidus muscle in patients with adolescent idiopathic scoliosis through evaluation by magnetic resonance imaging compared with histological analysis: a diagnostic accuracy study

scientific article published on 01 July 2019

Autophagy inhibited Ehrlich ascitic tumor cells apoptosis induced by the nitrostyrene derivative compounds: relationship with cytosolic calcium mobilization

scientific article published on 29 December 2011

Bauhinia forficata lectin (BfL) induces cell death and inhibits integrin-mediated adhesion on MCF7 human breast cancer cells.

scientific article published on 15 March 2014

Cafestol, a diterpene molecule found in coffee, induces leukemia cell death

scientific article

Calcium influx through L-type channels attenuates skeletal muscle contraction via inhibition of adenylyl cyclases

scientific article published on 17 October 2013

Canthin-6-one induces cell death, cell cycle arrest and differentiation in human myeloid leukemia cells.

scientific article published in February 2017

Cell-permeable gomesin peptide promotes cell death by intracellular Ca(2+) overload.

scientific article

Changes in human intervertebral disc biochemical composition and bony end plates between middle and old age

scientific article published in PLoS ONE

Changes in intracellular Ca2+ levels induced by cytokines and P2 agonists differentially modulate proliferation or commitment with macrophage differentiation in murine hematopoietic cells

scientific article

Characterization of Brown spider (Loxosceles intermedia) hemolymph: cellular and biochemical analyses.

scientific article published on 24 February 2015

Characterization of dual effects induced by antimicrobial peptides: regulated cell death or membrane disruption

scientific article

Chemical constituents and antileukemic activity of Eugenia dysenterica

scientific article published on 22 December 2016

Chemical reduction of carboxyl groups in heparin abolishes its vasodilatory activity

scientific article published on 01 April 2012

Chlorella vulgaris restores bone marrow cellularity and cytokine production in lead-exposed mice

article

Chlorella vulgaris treatment ameliorates the suppressive effects of single and repeated stressors on hematopoiesis

scientific article published on 12 December 2012

Comparison of Cytotoxic Activity in Leukemic Lineages Reveals Important Features of β-Hairpin Antimicrobial Peptides.

scientific article published on 17 December 2016

Comparison of treatments of peripheral arterial disease with mesenchymal stromal cells and mesenchymal stromal cells modified with granulocyte and macrophage colony-stimulating factor

scientific article published on 7 May 2013

Could a plant derived protein potentiate the anticancer effects of a stem cell in brain cancer?

scientific article

Cytotoxicity of phenothiazine derivatives associated with mitochondrial dysfunction: A structure-activity investigation

scientific article published on 14 February 2015

Differentiation of hematopoietic stem cell and myeloid populations by ATP is modulated by cytokines.

scientific article published on 02 June 2011

Divergent effects of Wnt5b on IL-3- and GM-CSF-induced myeloid differentiation

scientific article published on 17 December 2019

Dual role of P2 receptors during osteoblast differentiation

scientific article

Effects of Sleep Deprivation on Mice Bone Marrow and Spleen B Lymphopoiesis

scientific article published on 30 October 2015

Ent-7α-acetoxytrachyloban-18-oic acid and ent-7α-hydroxytrachyloban-18-oic acid from Xylopia langsdorfiana A. St-Hil. & Tul. modulate K(+) and Ca(2+) channels to reduce cytosolic calcium concentration on guinea pig ileum

scientific article published on 27 December 2011

Essential oil from Xylopia frutescens Aubl. reduces cytosolic calcium levels on guinea pig ileum: mechanism underlying its spasmolytic potential

scientific article published on 16 September 2015

Essential oil from the leaves of Xylopia langsdorfiana (Annonaceae) as a possible spasmolytic agent.

scientific article

Ethanolic Extract of Senna velutina Roots: Chemical Composition, In Vitro and In Vivo Antitumor Effects, and B16F10-Nex2 Melanoma Cell Death Mechanisms

scientific article published on 12 June 2019

Evaluation of In Vitro Antioxidant and Anticancer Properties of the Aqueous Extract from the Stem Bark of

scientific article published on 17 August 2018

Exercise and caloric restriction alter the immune system of mice submitted to a high-fat diet.

scientific article published on 13 March 2013

Flavonoid galetin 3,6-dimethyl ether attenuates guinea pig ileum contraction through K(+) channel activation and decrease in cytosolic calcium concentration

scientific article published on 6 October 2015

Fucan effect on CHO cell proliferation and migration.

scientific article

Functional and molecular evidence for heteromeric association of P2Y1 receptor with P2Y2 and P2Y4 receptors in mouse granulocytes

scientific article

Gemfibrozil Induces Anemia, Leukopenia and Reduces Hematopoietic Stem Cells via PPAR-α in Mice

scientific article published on 17 July 2020

Gomesin acts in the immune system and promotes myeloid differentiation and monocyte/macrophage activation in mouse.

scientific article published on 7 September 2016

Growth inhibitory activity of a novel lectin from Cliona varians against K562 human erythroleukemia cells.

scientific article

Hematopoietic modulators as potential agents for the treatment of leukemia

scientific article published on January 1, 2013

Hematopoietic stem cell expansion caused by a synthetic fragment of leptin

scientific article published on 01 October 2013

Heparan sulfate mediates trastuzumab effect in breast cancer cells

scientific article

Heparin induces rat aorta relaxation via integrin-dependent activation of muscarinic M3 receptors.

scientific article published on 30 August 2010

Heparin-integrin interaction in endothelial cells: Downstream signaling and heparan sulfate expression

scientific article published on 01 June 2012

Hydrogen peroxide (H2O2) induces leukemic but not normal hematopoietic cell death in a dose-dependent manner

scientific article published on 23 December 2013

Impaired Hematopoiesis and Disrupted Monocyte/Macrophage Homeostasis in Mucopolysaccharidosis Type I Mice.

scientific article published on 3 August 2015

Influence of protein corona on the transport of molecules into cells by mesoporous silica nanoparticles

scientific article published on 25 July 2013

Interface between breast cancer cells and the tumor microenvironment using platelet-rich plasma to promote tumor angiogenesis - influence of platelets and fibrin bundles on the behavior of breast tumor cells

scientific article

Internalization and degradation of heparin is not required for stimulus of heparan sulfate proteoglycan synthesis

scientific article

Involvement of P2 receptors in hematopoiesis and hematopoietic disorders, and as pharmacological targets

scientific article published on 20 December 2019

Ionic and biochemical characterization of bovine intervertebral disk

scientific article published on 04 March 2016

Kinin B1 receptor deficiency attenuates cisplatin-induced acute kidney injury by modulating immune cell migration

scientific article published on 20 December 2013

Leaf and Root Extracts from Campomanesia adamantium (Myrtaceae) Promote Apoptotic Death of Leukemic Cells via Activation of Intracellular Calcium and Caspase-3.

scientific article published on 14 August 2017

Leukemia stem cell immunophenotyping tool for diagnostic, prognosis, and therapeutics

scientific article published on 10 November 2019

Low-intensity pulsed ultrasound-dependent osteoblast proliferation occurs by via activation of the P2Y receptor: role of the P2Y1 receptor

scientific article published on 23 September 2009

Myelopoiesis modulation by ACE hyperfunction in kinin B(1) receptor knockout mice: relationship with AcSDKP levels.

scientific article

Nitric oxide-induced murine hematopoietic stem cell fate involves multiple signaling proteins, gene expression, and redox modulation.

scientific article published in November 2014

Organopalladium compound 7b targets mitochondrial thiols and induces caspase-dependent apoptosis in human myeloid leukemia cells

scientific article published on 6 June 2013

P2X(7) receptor in the kidneys of diabetic rats submitted to aerobic training or to N-acetylcysteine supplementation [corrected].

scientific article

P2X7 receptor activity regulation: the role of CD44 proteoglycan GAG chains

scientific article published on 26 November 2015

P2X7-induced apoptosis decreases by aging in mice myeloblasts

scientific article published on 22 December 2006

PLCγ2 and PKC are important to myeloid lineage commitment triggered by M-SCF and G-CSF.

scientific article published in January 2014

Palladacycle (BPC) antitumour activity against resistant and metastatic cell lines: the relationship with cytosolic calcium mobilisation and cathepsin B activity.

scientific article published on 28 March 2014

Palladacycles catalyse the oxidation of critical thiols of the mitochondrial membrane proteins and lead to mitochondrial permeabilization and cytochrome c release associated with apoptosis.

scientific article

Paradoxical sleep deprivation impairs mouse survival after infection with malaria parasites

scientific article published on 28 April 2015

Phosphoproteome reveals an atlas of protein signaling networks during osteoblast adhesion

scientific article

Pre-clinical antitumour evaluation of Biphosphinic Palladacycle Complex in human leukaemia cells

scientific article published on 5 November 2008

Primary Human Uterine Leiomyoma Cell Culture Quality Control: Some Properties of Myometrial Cells Cultured under Serum Deprivation Conditions in the Presence of Ovarian Steroids.

scientific article

Problems caused by high concentration of ATP on activation of the P2X7 receptor in bone marrow cells loaded with the Ca2+ fluorophore fura-2.

scientific article

Profiling the changes in signaling pathways in ascorbic acid/β-glycerophosphate-induced osteoblastic differentiation

scientific article published on 01 January 2011

Promyelocytic leukemia protein in mesenchymal stem cells is essential for leukemia progression

scientific article published on 01 August 2018

Requirement for PLCγ2 in IL-3 and GM-CSF-stimulated MEK/ERK phosphorylation in murine and human hematopoietic stem/progenitor cells.

scientific article

Resistance to degradation and cellular distribution are important features for the antitumor activity of gomesin

scientific article

Riboflavin and photoproducts in MC3T3-E1 differentiation

scientific article published on 3 August 2010

Simple Method to Genotype the ACTN3 r577x Polymorphism.

scientific article published in April 2015

Sleep deprivation impairs calcium signaling in mouse splenocytes and leads to a decreased immune response.

scientific article

The ACTN3 R577X polymorphism affects the lipid profile and the prognosis of nutritional intervention in HIV-positive patients.

scientific article

The Chemical Profile of Senna velutina Leaves and Their Antioxidant and Cytotoxic Effects

scientific article (publication date: 2016)

The impaired viability of prostate cancer cell lines by the recombinant plant kallikrein inhibitor.

scientific article published on 19 March 2013

Therapeutic ultrasound promotes plasmid DNA uptake by clathrin-mediated endocytosis

scientific article published on July 2011

[1-8-NαC]-Zanriorb A1, a Proapoptotic Orbitide from Leaves of Zanthoxylum riedelianum.

scientific article

α-Tocopherol induces hematopoietic stem/progenitor cell expansion and ERK1/2-mediated differentiation

scientific article

γ-Rays-generated ROS induce apoptosis via mitochondrial and cell cycle alteration in smooth muscle cells.

scientific article published on 2 May 2014