List of works - Markus Fendt

2,3,5-Trimethyl-3-thiazoline (TMT), a component of fox odor - just repugnant or really fear-inducing?

scientific article published on 15 May 2008

5,7-dihydroxytryptamine injections into the prefrontal cortex and nucleus accumbens differently affect prepulse inhibition and baseline startle magnitude in rats.

scientific article published on 21 March 2009

Altered NMDA receptor expression and behavior following postnatal hypoxia: potential relevance to schizophrenia.

scientific article published on 23 October 2006

Amphetamine injections into the nucleus accumbens affect neither acquisition/expression of conditioned fear nor baseline startle response

scientific article published on 10 December 2004

Amygdaloid N-methyl-D-aspartate and gamma-aminobutyric acid(A) receptors regulate sensorimotor gating in a dopamine-dependent way in rats

scientific article published in January 2000

Amygdaloid metabotropic glutamate receptor subtype 7 is involved in the acquisition of conditioned fear

scientific article published in July 2008

Amygdaloid noradrenaline is involved in the sensitization of the acoustic startle response in rats

scientific article published in June 1994

Anxiogenic-like effects of opiate withdrawal seen in the fear-potentiated startle test, an interdisciplinary probe for drug-related motivational states

scientific article

Aversion- vs fear-inducing properties of 2,4,5-trimethyl-3-thiazoline, a component of fox odor, in comparison with those of butyric acid.

scientific article published in August 2009

Behavioral analysis of narcoleptic episodes in orexin-deficient mice.

scientific article published on 13 December 2013

Behavioral changes induced in rats by exposure to trimethylthiazoline, a component of fox odor

scientific article published in August 2005

Behavioural alterations in rats following neonatal hypoxia and effects of clozapine: implications for schizophrenia

scientific article published in July 2008

Benzimidazoles as Potent and Orally Active mGlu5 Receptor Antagonists with an Improved PK Profile

scientific article published on 2 November 2010

Blocking metabotropic glutamate receptor subtype 7 (mGlu7) via the Venus flytrap domain (VFTD) inhibits amygdala plasticity, stress, and anxiety-related behavior

scientific article

Carbachol injections into the nucleus accumbens disrupt acquisition and expression of fear-potentiated startle and freezing in rats

scientific article published on 3 April 2006

Carbachol injections into the nucleus accumbens induce 50 kHz calls in rats

scientific article published on 24 March 2006

Cholinergic modulation of the acoustic startle response in the caudal pontine reticular nucleus of the rat.

scientific article

Chronic inhibition of GABA synthesis in the infralimbic cortex facilitates conditioned safety memory and reduces contextual fear

scientific article published on 24 April 2020

Clonidine injections into the lateral nucleus of the amygdala block acquisition and expression of fear-potentiated startle

scientific article published in January 2002

Clozapine attenuates the locomotor sensitisation and the prepulse inhibition deficit induced by a repeated oral administration of Catha edulis extract and cathinone in rats

scientific article published on 5 February 2005

Conditioned behavioral responses to a context paired with the predator odor trimethylthiazoline

scientific article published in June 2007

Corticotropin-releasing factor in the caudal pontine reticular nucleus mediates the expression of fear-potentiated startle in the rat.

scientific article published in February 1997

Deficiency of the immunoproteasome subunit β5i/LMP7 supports the anxiogenic effects of mild stress and facilitates cued fear memory in mice

scientific article published on 20 February 2019

Detecting danger--or just another odorant? Olfactory sensitivity for the fox odor component 2,4,5-trimethylthiazoline in four species of mammals

scientific article published on 15 December 2004

Detection and avoidance of a carnivore odor by prey

scientific journal article

Different regions of the periaqueductal grey are involved differently in the expression and conditioned inhibition of fear-potentiated startle

scientific article published in December 1998

Differential effects of wake promoting drug modafinil in aversive learning paradigms.

scientific article

Differential expression of presynaptic genes in a rat model of postnatal hypoxia: relevance to schizophrenia.

scientific article

Differential roles of mGlu(7) and mGlu(8) in amygdala-dependent behavior and physiology

scientific article published on 7 May 2013

Discovery of 1H-pyrazolo[3,4-b]pyridines as potent dual orexin receptor antagonists (DORAs).

scientific article published on 19 October 2015

Distinct effects of IPSU and suvorexant on mouse sleep architecture

scientific article published on 10 December 2013

Dopamine D1 receptors and adenosine A1 receptors in the rat nucleus accumbens regulate motor activity but not prepulse inhibition

scientific article

Editorial: Scents that Matter-from Olfactory Stimuli to Genes, Behaviors and Beyond.

scientific article published on 09 February 2016

Effects of clonidine injections into the bed nucleus of the stria terminalis on fear and anxiety behavior in rats

scientific article published on 19 December 2004

Effects of the mGluR8 agonist (S)-3,4-DCPG in the lateral amygdala on acquisition/expression of fear-potentiated startle, synaptic transmission, and plasticity.

scientific article published on 26 September 2005

Enhancement of prepulse inhibition after blockade of GABA activity within the superior colliculus

scientific article

Ergoline-derived inverse agonists of the human h3 receptor for the treatment of narcolepsy.

scientific article

Exposure to urine of canids and felids, but not of herbivores, induces defensive behavior in laboratory rats

scientific article published on 01 December 2006

Expression and conditioned inhibition of fear-potentiated startle after stimulation and blockade of AMPA/Kainate and GABA(A) receptors in the dorsal periaqueductal gray

scientific article published in October 2000

Expression of freezing and fear-potentiated startle during sustained fear in mice.

scientific article published on 25 March 2015

Fox urine exposure induces avoidance behavior in rats and activates the amygdalar olfactory cortex

scientific article published on 15 November 2014

Gastrin-Releasing Peptide Signaling Plays a Limited and Subtle Role in Amygdala Physiology and Aversive Memory ⬇️

scientific article published on April 11, 2012

Group III metabotropic glutamate receptors inhibit startle-mediating giant neurons in the caudal pontine reticular nucleus but do not mediate synaptic depression/short-term habituation of startle

scientific article published on August 2010

Identification of a novel series of orexin receptor antagonists with a distinct effect on sleep architecture for the treatment of insomnia

scientific article published on 18 September 2013

Immediate and punitive impact of mechanosensory disturbance on olfactory behaviour of larval Drosophila.

scientific article

Inactivation of the lateral septum blocks fox odor-induced fear behavior

scientific article published in April 2008

Increased anxiety but normal fear and safety learning in orexin-deficient mice

scientific article published on 10 December 2016

Injections of the somatostatin receptor type 2 agonist L-054,264 into the amygdala block expression but not acquisition of conditioned fear in rats

scientific article published on 15 February 2014

Innate or learned acoustic recognition of avian predators in rodents?

scientific article published in February 2009

Intra-amygdala injections of neuropeptide S block fear-potentiated startle

scientific article published on 15 March 2010

Kinetic properties of "dual" orexin receptor antagonists at OX1R and OX2R orexin receptors

scientific article published on 3 December 2013

Lesions of the central gray block conditioned fear as measured with the potentiated startle paradigm

scientific article published in January 1996

Lesions of the central gray block the sensitization of the acoustic startle response in rats

scientific article published on October 1994

Lesions of the dorsal hippocampus block trace fear conditioned potentiation of startle

scientific article published in June 2005

Memory enhancement by ferulic acid ester across species

scientific article published on 24 October 2018

Metabotropic glutamate receptors are involved in amygdaloid plasticity

scientific article published in May 2002

NMDA receptors in the pontine brainstem are necessary for fear potentiation of the startle response

scientific article published in December 1996

Narcoleptic episodes in orexin-deficient mice are increased by both attractive and aversive odors

scientific article

Neuropeptide S receptor deficiency modulates spontaneous locomotor activity and the acoustic startle response

scientific article published in October 2010

Noradrenaline transmission within the ventral bed nucleus of the stria terminalis is critical for fear behavior induced by trimethylthiazoline, a component of fox odor.

scientific article published in June 2005

Observational Fear Learning in Rats: Role of Trait Anxiety and Ultrasonic Vocalization

scientific article published in 2021

Olfactory neuron-specific expression of A30P α-synuclein exacerbates dopamine deficiency and hyperactivity in a novel conditional model of early Parkinson's disease stages

scientific article

Onset and offset of aversive events establish distinct memories requiring fear and reward networks

scientific article published on 16 October 2012

Pain-relief learning in flies, rats, and man: basic research and applied perspectives

scientific article

Pharmacological interference with metabotropic glutamate receptor subtype 7 but not subtype 5 differentially affects within- and between-session extinction of Pavlovian conditioned fear.

scientific article published on 10 November 2011

Piperidyl amides as novel, potent and orally active mGlu5 receptor antagonists with anxiolytic-like activity

scientific article published on 5 November 2009

Predator odor exposure increases food-carrying behavior in rats

scientific article published on 7 November 2015

Prefrontal dopamine D4 receptors are involved in encoding fear extinction

scientific journal article

Relief learning is dependent on NMDA receptor activation in the nucleus accumbens

scientific article

Relief learning is distinguished from safety learning by the requirement of the nucleus accumbens.

scientific article published on July 2014

Relief learning requires a coincident activation of dopamine D1 and NMDA receptors within the nucleus accumbens.

scientific article published on 25 November 2016

Relief memory consolidation requires protein synthesis within the nucleus accumbens

scientific article published on 11 January 2016

Role of the substantia nigra pars reticulata in sensorimotor gating, measured by prepulse inhibition of startle in rats

scientific article published in December 2000

Sensitization of prepulse inhibition deficits by repeated administration of dizocilpine.

scientific article

Standardized extract of Ficus platyphylla reverses apomorphine-induced changes in prepulse inhibition and locomotor activity in rats

scientific article

Synchronous evolution of an odor biosynthesis pathway and behavioral response

scientific journal article

TMT-induced autonomic and behavioral changes and the neural basis of its processing.

scientific article

Temporary inactivation of the anterior part of the bed nucleus of the stria terminalis blocks alarm pheromone-induced defensive behavior in rats.

scientific article

Temporary inactivation of the medial and basolateral amygdala differentially affects TMT-induced fear behavior in rats

scientific article

Temporary inactivation of the nucleus accumbens disrupts acquisition and expression of fear-potentiated startle in rats.

scientific article

Temporary inactivation of the perirhinal cortex by muscimol injections block acquisition and expression of fear-potentiated startle

scientific article published in February 2004

Temporary inactivation of the rostral perirhinal cortex induces an anxiolytic-like effect on the elevated plus-maze and on the yohimbine-enhanced startle response

scientific article published on September 2005

The acoustic startle response in inbred Roman high- and low-avoidance rats

scientific article published in November 1997

The dual orexin receptor antagonist almorexant induces sleep and decreases orexin-induced locomotion by blocking orexin 2 receptors

scientific article

The effect of mGlu8 deficiency in animal models of psychiatric diseases

scientific article published on 8 August 2009

The effects of muscimol and AMN082 injections into the medial prefrontal cortex on the expression and extinction of conditioned fear in mice

scientific article published in April 2012

The metabotropic glutamate receptor antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP) blocks fear conditioning in rats

scientific article published in July 2001

The neuroanatomical and neurochemical basis of conditioned fear.

scientific article

The norepinephrine reuptake inhibitor reboxetine is more potent in treating murine narcoleptic episodes than the serotonin reuptake inhibitor escitalopram

scientific article

The olfactory hole-board test in rats: a new paradigm to study aversion and preferences to odors.

scientific article

The superior olivary complex is necessary for the full expression of the acoustic but not tactile startle response in rats

scientific article published on 01 March 2000

Translational value of startle modulations ⬇️

scientific article published on March 23, 2013

[Drug treatment of Alzheimer's dementia : Status quo and perspectives]

scientific article published on 01 July 2019

mGluR7 facilitates extinction of aversive memories and controls amygdala plasticity

scientific article published on 21 August 2007

List of works by Markus Fendt

2,3,5-Trimethyl-3-thiazoline (TMT), a component of fox odor - just repugnant or really fear-inducing?

5,7-dihydroxytryptamine injections into the prefrontal cortex and nucleus accumbens differently affect prepulse inhibition and baseline startle magnitude in rats.

Altered NMDA receptor expression and behavior following postnatal hypoxia: potential relevance to schizophrenia.

Amphetamine injections into the nucleus accumbens affect neither acquisition/expression of conditioned fear nor baseline startle response

Amygdaloid N-methyl-D-aspartate and gamma-aminobutyric acid(A) receptors regulate sensorimotor gating in a dopamine-dependent way in rats

Amygdaloid metabotropic glutamate receptor subtype 7 is involved in the acquisition of conditioned fear

Amygdaloid noradrenaline is involved in the sensitization of the acoustic startle response in rats

Anxiogenic-like effects of opiate withdrawal seen in the fear-potentiated startle test, an interdisciplinary probe for drug-related motivational states

Aversion- vs fear-inducing properties of 2,4,5-trimethyl-3-thiazoline, a component of fox odor, in comparison with those of butyric acid.

Behavioral analysis of narcoleptic episodes in orexin-deficient mice.

Behavioral changes induced in rats by exposure to trimethylthiazoline, a component of fox odor

Behavioural alterations in rats following neonatal hypoxia and effects of clozapine: implications for schizophrenia

Benzimidazoles as Potent and Orally Active mGlu5 Receptor Antagonists with an Improved PK Profile

Blocking metabotropic glutamate receptor subtype 7 (mGlu7) via the Venus flytrap domain (VFTD) inhibits amygdala plasticity, stress, and anxiety-related behavior

Carbachol injections into the nucleus accumbens disrupt acquisition and expression of fear-potentiated startle and freezing in rats

Carbachol injections into the nucleus accumbens induce 50 kHz calls in rats

Cholinergic modulation of the acoustic startle response in the caudal pontine reticular nucleus of the rat.

Chronic inhibition of GABA synthesis in the infralimbic cortex facilitates conditioned safety memory and reduces contextual fear

Clonidine injections into the lateral nucleus of the amygdala block acquisition and expression of fear-potentiated startle

Clozapine attenuates the locomotor sensitisation and the prepulse inhibition deficit induced by a repeated oral administration of Catha edulis extract and cathinone in rats

Conditioned behavioral responses to a context paired with the predator odor trimethylthiazoline

Corticotropin-releasing factor in the caudal pontine reticular nucleus mediates the expression of fear-potentiated startle in the rat.

Deficiency of the immunoproteasome subunit β5i/LMP7 supports the anxiogenic effects of mild stress and facilitates cued fear memory in mice

Detecting danger--or just another odorant? Olfactory sensitivity for the fox odor component 2,4,5-trimethylthiazoline in four species of mammals

Detection and avoidance of a carnivore odor by prey

Different regions of the periaqueductal grey are involved differently in the expression and conditioned inhibition of fear-potentiated startle

Differential effects of wake promoting drug modafinil in aversive learning paradigms.

Differential expression of presynaptic genes in a rat model of postnatal hypoxia: relevance to schizophrenia.

Differential roles of mGlu(7) and mGlu(8) in amygdala-dependent behavior and physiology

Discovery of 1H-pyrazolo[3,4-b]pyridines as potent dual orexin receptor antagonists (DORAs).

Distinct effects of IPSU and suvorexant on mouse sleep architecture

Dopamine D1 receptors and adenosine A1 receptors in the rat nucleus accumbens regulate motor activity but not prepulse inhibition

Editorial: Scents that Matter-from Olfactory Stimuli to Genes, Behaviors and Beyond.

Effects of clonidine injections into the bed nucleus of the stria terminalis on fear and anxiety behavior in rats

Effects of the mGluR8 agonist (S)-3,4-DCPG in the lateral amygdala on acquisition/expression of fear-potentiated startle, synaptic transmission, and plasticity.

Enhancement of prepulse inhibition after blockade of GABA activity within the superior colliculus

Ergoline-derived inverse agonists of the human h3 receptor for the treatment of narcolepsy.

Exposure to urine of canids and felids, but not of herbivores, induces defensive behavior in laboratory rats

Expression and conditioned inhibition of fear-potentiated startle after stimulation and blockade of AMPA/Kainate and GABA(A) receptors in the dorsal periaqueductal gray

Expression of freezing and fear-potentiated startle during sustained fear in mice.

Fox urine exposure induces avoidance behavior in rats and activates the amygdalar olfactory cortex

Gastrin-Releasing Peptide Signaling Plays a Limited and Subtle Role in Amygdala Physiology and Aversive Memory ⬇️

Group III metabotropic glutamate receptors inhibit startle-mediating giant neurons in the caudal pontine reticular nucleus but do not mediate synaptic depression/short-term habituation of startle

Identification of a novel series of orexin receptor antagonists with a distinct effect on sleep architecture for the treatment of insomnia

Immediate and punitive impact of mechanosensory disturbance on olfactory behaviour of larval Drosophila.

Inactivation of the lateral septum blocks fox odor-induced fear behavior

Increased anxiety but normal fear and safety learning in orexin-deficient mice

Injections of the somatostatin receptor type 2 agonist L-054,264 into the amygdala block expression but not acquisition of conditioned fear in rats

Innate or learned acoustic recognition of avian predators in rodents?

Intra-amygdala injections of neuropeptide S block fear-potentiated startle

Kinetic properties of "dual" orexin receptor antagonists at OX1R and OX2R orexin receptors

Lesions of the central gray block conditioned fear as measured with the potentiated startle paradigm

Lesions of the central gray block the sensitization of the acoustic startle response in rats

Lesions of the dorsal hippocampus block trace fear conditioned potentiation of startle

Memory enhancement by ferulic acid ester across species

Metabotropic glutamate receptors are involved in amygdaloid plasticity

NMDA receptors in the pontine brainstem are necessary for fear potentiation of the startle response

Narcoleptic episodes in orexin-deficient mice are increased by both attractive and aversive odors

Neuropeptide S receptor deficiency modulates spontaneous locomotor activity and the acoustic startle response

Noradrenaline transmission within the ventral bed nucleus of the stria terminalis is critical for fear behavior induced by trimethylthiazoline, a component of fox odor.

Observational Fear Learning in Rats: Role of Trait Anxiety and Ultrasonic Vocalization

Olfactory neuron-specific expression of A30P α-synuclein exacerbates dopamine deficiency and hyperactivity in a novel conditional model of early Parkinson's disease stages

Onset and offset of aversive events establish distinct memories requiring fear and reward networks

Pain-relief learning in flies, rats, and man: basic research and applied perspectives

Pharmacological interference with metabotropic glutamate receptor subtype 7 but not subtype 5 differentially affects within- and between-session extinction of Pavlovian conditioned fear.

Piperidyl amides as novel, potent and orally active mGlu5 receptor antagonists with anxiolytic-like activity

Predator odor exposure increases food-carrying behavior in rats

Prefrontal dopamine D4 receptors are involved in encoding fear extinction

Relief learning is dependent on NMDA receptor activation in the nucleus accumbens

Relief learning is distinguished from safety learning by the requirement of the nucleus accumbens.

Relief learning requires a coincident activation of dopamine D1 and NMDA receptors within the nucleus accumbens.

Relief memory consolidation requires protein synthesis within the nucleus accumbens

Role of the substantia nigra pars reticulata in sensorimotor gating, measured by prepulse inhibition of startle in rats

Sensitization of prepulse inhibition deficits by repeated administration of dizocilpine.

Standardized extract of Ficus platyphylla reverses apomorphine-induced changes in prepulse inhibition and locomotor activity in rats

Synchronous evolution of an odor biosynthesis pathway and behavioral response

TMT-induced autonomic and behavioral changes and the neural basis of its processing.

Temporary inactivation of the anterior part of the bed nucleus of the stria terminalis blocks alarm pheromone-induced defensive behavior in rats.

Temporary inactivation of the medial and basolateral amygdala differentially affects TMT-induced fear behavior in rats