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List of works by Walter Berger

2-deprenyl-rheediaxanthone B isolated from Metaxya rostrata induces active cell death in colorectal tumor cells

scientific article (publication date: 2013)

A Multi-Threading Architecture to Support Interactive Visual Exploration

scientific article published on 01 November 2009

A SAR study of novel antiproliferative ruthenium and osmium complexes with quinoxalinone ligands in human cancer cell lines

scientific article

A bicistronic baculovirus vector for transient and stable protein expression in mammalian cells.

scientific article

A human model of epithelial to mesenchymal transition to monitor drug efficacy in hepatocellular carcinoma progression

scientific article published on March 2011

A model for structure-based comparison of many categories in small-multiple displays

scientific article published on December 2013

A novel bioassay for P-glycoprotein functionality using cytochalasin D

scientific article published on 01 March 1998

A novel class of bis- and tris-chelate diam(m)inebis(dicarboxylato)platinum(IV) complexes as potential anticancer prodrugs.

scientific article

A small upstream open reading frame causes inhibition of human major vault protein expression from a ubiquitous mRNA splice variant

scientific article (publication date: 6 April 2001)

Acquired nintedanib resistance in FGFR1-driven small cell lung cancer: role of endothelin-A receptor-activated ABCB1 expression

scientific article

Active vitamin D potentiates the anti-neoplastic effects of calcium in the colon: A cross talk through the calcium-sensing receptor

scientific article

Activins and follistatins: Emerging roles in liver physiology and cancer

scientific article

Aggressiveness of human melanoma xenograft models is promoted by aneuploidy-driven gene expression deregulation

scientific article

Altered membrane rigidity via enhanced endogenous cholesterol synthesis drives cancer cell resistance to destruxins.

scientific article published on 22 May 2018

An Organoruthenium Anticancer Agent Shows Unexpected Target Selectivity For Plectin.

scientific article published on 26 May 2017

An albumin-based tumor-targeted oxaliplatin prodrug with distinctly improved anticancer activity in vivo.

scientific article

Anion-Exchange Chromatography Coupled to High-Resolution Mass Spectrometry: A Powerful Tool for Merging Targeted and Non-targeted Metabolomics

scientific article

Another step toward DNA selective targeting: Ni(II) and Cu(II) complexes of a Schiff base ligand able to bind gene promoter G-quadruplexes

scientific article

Anticancer Activity of Metal Complexes: Involvement of Redox Processes ⬇️

scientific article published on May 11, 2011

Anticancer activity of methyl-substituted oxaliplatin analogs

scientific article published on 13 February 2012

Anticancer activity of the lanthanum compound [tris(1,10-phenanthroline)lanthanum(III)]trithiocyanate (KP772; FFC24).

scientific article published on 15 December 2005

Anticancer effects of zoledronic acid against human osteosarcoma cells.

scientific article published on June 2006

Anticancer metal drugs and immunogenic cell death.

scientific article published on 16 June 2016

Apelin promotes lymphangiogenesis and lymph node metastasis.

scientific article

Application of C60 Fullerene-Doxorubicin Complex for Tumor Cell Treatment In Vitro and In Vivo.

scientific article published in July 2015

Bacterial ghosts as adjuvant to oxaliplatin chemotherapy in colorectal carcinomatosis

scientific article published on 16 February 2018

Behavior of platinum(iv) complexes in models of tumor hypoxia: cytotoxicity, compound distribution and accumulation

scientific article published on 10 February 2016

Bilberry extract, its major polyphenolic compounds, and the soy isoflavone genistein antagonize the cytostatic drug erlotinib in human epithelial cells

scientific article published on 3 August 2016

Bimodal expression of Sprouty2 during the cell cycle is mediated by phase-specific Ras/MAPK and c-Cbl activities

scientific article

Bioimaging of isosteric osmium and ruthenium anticancer agents by LA-ICP-MS.

scientific article published on 7 March 2018

Biological activity of Pt prodrugs triggered by riboflavin-mediated bioorthogonal photocatalysis

scientific article published in Scientific Reports

CD44 drives aggressiveness and chemoresistance of a metastatic human osteosarcoma xenograft model

scientific article

Calpain-mediated integrin deregulation as a novel mode of action for the anticancer gallium compound KP46.

scientific article

Cancer Cell Resistance Against the Clinically Investigated Thiosemicarbazone COTI-2 Is Based on Formation of Intracellular Copper Complex Glutathione Adducts and ABCC1-Mediated Efflux

scientific article published on 15 November 2020

Canine and human sarcomas exhibit predominant FGFR1 expression and impaired viability after inhibition of signaling.

scientific article published on 9 April 2014

Cell migration or cytokinesis and proliferation?--revisiting the "go or grow" hypothesis in cancer cells in vitro.

scientific article

Cellular functions of vaults and their involvement in multidrug resistance.

scientific article published on August 2006

Cerebrospinal Fluid Penetration and Combination Therapy of Entrectinib for Disseminated <i>ROS1/NTRK</i>-Fusion Positive Pediatric High-Grade Glioma

scientific article published on 18 December 2020

Chromosomal dynamics of cell cycle regulator gene p21 during transcriptional activation ⬇️

scientific article published on October 23, 2010

Chromosomal imbalances in primary and metastatic melanomas: over-representation of essential telomerase genes

scientific article published on October 2003

Chronic arsenic trioxide exposure leads to enhanced aggressiveness via Met oncogene addiction in cancer cells

scientific article published on 28 March 2016

Circulating activin A is a novel prognostic biomarker in malignant pleural mesothelioma - A multi-institutional study.

scientific article published on 8 June 2016

Circulating complement component 4d (C4d) correlates with tumor volume, chemotherapeutic response and survival in patients with malignant pleural mesothelioma.

scientific article published on 28 November 2017

Circulating fibrinogen is a prognostic and predictive biomarker in malignant pleural mesothelioma

scientific article published on 16 January 2014

Combined MEK and PI3K/p110β Inhibition as a Novel Targeted Therapy for Malignant Mesothelioma Displaying Sarcomatoid Features

scientific article published on 07 January 2020

Combined proteomics/miRNomics of dendritic cell immunotherapy-treated glioblastoma patients as a screening for survival-associated factors

scientific article published on 16 January 2020

Comparative in vitro and in vivo pharmacological investigation of platinum(IV) complexes as novel anticancer drug candidates for oral application.

scientific article

Comparative studies of oxaliplatin-based platinum(iv) complexes in different in vitro and in vivo tumor models

scientific article

Computed determination of the in vitro optimal chemocombinations of sphaeropsidin A with chemotherapeutic agents to combat melanomas

scientific article

Cytogenetic and comparative genomic hybridization findings in four cases of breast cancer after neoadjuvant chemotherapy.

scientific article

DNA damage, somatic aneuploidy, and malignant sarcoma susceptibility in muscular dystrophies

scientific article

DR-01NOVEL PEDIATRIC EPENDYMOMA MODELS SHOW HIGH CHEMOTHERAPY-RESISTANCE AND HYPERACTIVATION OF ABC-TRANSPORTERS.

scientific article published in November 2014

Deciphering the chemical instability of sphaeropsidin A under physiological conditions - degradation studies and structural elucidation of the major metabolite

scientific article published on 05 October 2020

Deregulation of the activin/follistatin system in hepatocarcinogenesis

scientific article

Design, synthesis, nuclear localization, and biological activity of a fluorescent duocarmycin analog, HxTfA.

scientific article published on 5 March 2018

Destruxins: fungal-derived cyclohexadepsipeptides with multifaceted anticancer and antiangiogenic activities

scientific article published on 6 June 2013

Detection and quantification of transcripts for the catalytic subunit TERT and the RNA component of telomerase in rat tissue

scientific article published on June 2003

Differences in protein binding and excretion of Triapine and its Fe(III) complex

scientific article published on 19 October 2015

Differential effects of polymorphic alleles of FGF receptor 4 on colon cancer growth and metastasis

scientific article

Discovery and Characterization of R/S-N-3-Cyanophenyl-N'-(6-tert-butoxycarbonylamino-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-4-yl)urea, a New Histone Deacetylase Class III Inhibitor Exerting Antiproliferative Activity against Cancer Cell Lines.

scientific article

Distinct Epidemiology and Clinical Consequence of Classic Versus Rare EGFR Mutations in Lung Adenocarcinoma.

scientific article published on May 2015

Distinct activity of the bone-targeted gallium compound KP46 against osteosarcoma cells - synergism with autophagy inhibition

scientific article

Down-regulation of Sprouty2 in non-small cell lung cancer contributes to tumor malignancy via extracellular signal-regulated kinase pathway-dependent and -independent mechanisms

scientific article published on May 2007

Downregulation of TSLC1 and DAL-1 expression occurs frequently in breast cancer

scientific article published on 27 January 2007

Dual inhibition of EGFR and mTOR pathways in small cell lung cancer.

scientific article

Dynamics of CRISPR/Cas9-mediated genomic editing of the AXL locus in hepatocellular carcinoma cells.

scientific article published on 13 December 2017

Dysregulated Expression of the MicroRNA miR-137 and Its Target YBX1 Contribute to the Invasive Characteristics of Malignant Pleural Mesothelioma.

scientific article published on 4 November 2017

EGCG-meditated cyto- and genotoxicity in HaCat keratinocytes is impaired by cell-mediated clearance of auto-oxidation-derived H2O2: an algorithm for experimental setting correction

scientific article published on 15 June 2011

EGFR is not a major driver for osteosarcoma cell growth in vitro but contributes to starvation and chemotherapy resistance.

scientific article published on 2 November 2015

EGFR-targeting peptide-coupled platinum(IV) complexes.

scientific article

EVI1 inhibits apoptosis induced by antileukemic drugs via upregulation of CDKN1A/p21/WAF in human myeloid cells

scientific article

EVI1 promotes tumor growth via transcriptional repression of MS4A3.

scientific article published on 21 March 2015

Ecdysteroids sensitize MDR and non-MDR cancer cell lines to doxorubicin, paclitaxel, and vincristine but tend to protect them from cisplatin

scientific article published on 17 May 2015

Effect of 1,25-dihydroxyvitamin D3 on the Wnt pathway in non-malignant colonic cells.

scientific article

Effects of multidrug resistance-related ATP-binding-cassette transporter proteins on the cytoskeletal activity of cytochalasins

scientific article published in December 1997

Effects of the anthelmintic drug PF1022A on mammalian tissue and cells

scientific article

Electronic State of Sodium trans-[Tetrachloridobis(1H-indazole)ruthenate(III)] (NKP-1339) in Tumor, Liver and Kidney Tissue of a SW480-bearing Mouse.

scientific article published on 23 January 2017

Enhanced anticancer activity and circumvention of resistance mechanisms by novel polymeric/ phospholipidic nanocarriers of doxorubicin

scientific article published on July 2014

Enniatin exerts p53-dependent cytostatic and p53-independent cytotoxic activities against human cancer cells

scientific article published on 28 February 2007

Epigenetic down-regulation of integrin α7 increases migratory potential and confers poor prognosis in malignant pleural mesothelioma.

scientific article published on 26 May 2015

Erythropoietin receptor expression is a potential prognostic factor in human lung adenocarcinoma

scientific article

Evidence for a role of FGF-2 and FGF receptors in the proliferation of non-small cell lung cancer cells

scientific article

Ex-vivo analysis of quantitative 5-ALA fluorescence intensity in diffusely infiltrating gliomas using a handheld spectroscopic probe: Correlation with histopathology, proliferation and microvascular density

scientific article published on 16 May 2019

Expression of FGFR1-4 in Malignant Pleural Mesothelioma Tissue and Corresponding Cell Lines and its Relationship to Patient Survival and FGFR Inhibitor Sensitivity

scientific article published on 16 September 2019

Expression of the lung resistance-related protein in human and rat hepatocarcinogenesis

scientific article published in November 2002

Expression of the major vault protein LRP in human non-small-cell lung cancer cells: activation by short-term exposure to antineoplastic drugs

scientific article published on October 2000

Expression of the multidrug resistance-associated protein (MRP) and chemoresistance of human non-small-cell lung cancer cells

scientific article published on September 1997

FGF18 in colorectal tumour cells: autocrine and paracrine effects

scientific article

FGF2 and EGF induce epithelial-mesenchymal transition in malignant pleural mesothelioma cells via a MAPKinase/MMP1 signal.

scientific article published in April 2018

FGF5 as an oncogenic factor in human glioblastoma multiforme: autocrine and paracrine activities

scientific article published on 24 March 2008

FGF5 is expressed in melanoma and enhances malignancy in vitro and in vivo.

scientific article published on 23 September 2017

FGF8 induces therapy resistance in neoadjuvantly radiated rectal cancer

scientific article published on 01 October 2018

Fibroblast growth factor receptor 3 isoforms: Novel therapeutic targets for hepatocellular carcinoma?

scientific article published in August 2015

Fibroblast growth factor receptor 3-IIIc mediates colorectal cancer growth and migration.

scientific article

Fibroblast growth factor receptor 4 induced resistance to radiation therapy in colorectal cancer

scientific article published on 17 September 2016

Fibroblast growth factor receptor 4: a putative key driver for the aggressive phenotype of hepatocellular carcinoma.

scientific article

Fibroblast growth factor receptors as therapeutic targets in human melanoma: synergism with BRAF inhibition

scientific article

Functional classification of cellular proteome profiles support the identification of drug resistance signatures in melanoma cells.

scientific article published on 19 June 2013

Galectin 1 proangiogenic and promigratory effects in the Hs683 oligodendroglioma model are partly mediated through the control of BEX2 expression

scientific article published on May 2009

Galectin-1 is implicated in the protein kinase C epsilon/vimentin-controlled trafficking of integrin-beta1 in glioblastoma cells

scientific article

Gliomasphere marker combinatorics: multidimensional flow cytometry detects CD44+/CD133+/ITGA6+/CD36+ signature

scientific article published on 22 November 2018

Green tea extract and (-)-epigallocatechin-3-gallate, the major tea catechin, exert oxidant but lack antioxidant activities.

scientific article

Hellebrin and its aglycone form hellebrigenin display similar in vitro growth inhibitory effects in cancer cells and binding profiles to the alpha subunits of the Na+/K+-ATPase

scientific article published on 26 April 2013

Heterocyclic complexes of ruthenium(III) induce apoptosis in colorectal carcinoma cells.

scientific article published on 16 October 2004

High circulating activin A level is associated with tumor progression and predicts poor prognosis in lung adenocarcinoma.

scientific article

High rate of FGFR1 amplifications in brain metastases of squamous and non-squamous lung cancer.

scientific article published on 17 October 2013

Human tripartite motif protein 52 is required for cell context-dependent proliferation.

scientific article published on 5 February 2018

Hydrogen peroxide mediates EGCG-induced antioxidant protection in human keratinocytes

scientific article published on 12 August 2010

Impact of CYP24A1 overexpression on growth of colorectal tumour xenografts in mice fed with vitamin D and soy.

scientific article published on 3 August 2015

Impact of Stepwise NH2-Methylation of Triapine on the Physicochemical Properties, Anticancer Activity, and Resistance Circumvention

scientific article published on 23 June 2016

Impact of metal coordination on cytotoxicity of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (triapine) and novel insights into terminal dimethylation.

scientific article published in August 2009

Impact of terminal dimethylation on the resistance profile of α-N-heterocyclic thiosemicarbazones

scientific article published on 15 March 2012

In vitro studies on cisplatin focusing on kinetic aspects of intracellular chemistry by LC-ICP-MS.

scientific article published in June 2013

Influence of ascorbic acid on the activity of the investigational anticancer drug KP1019.

scientific article published on 26 June 2011

Influence of extracellular pH on the cytotoxicity, cellular accumulation, and DNA interaction of novel pH-sensitive 2-aminoalcoholatoplatinum(II) complexes

scientific article published on 26 January 2013

Interaction between fatty acid synthase- and ErbB-systems in ovarian cancer cells

scientific article

Interaction of FGF9 with FGFR3-IIIb/IIIc, a putative driver of growth and aggressive behavior of hepatocellular carcinoma

scientific article published on 07 May 2020

Interactions between ABC-transport proteins and the secondary Fusarium metabolites enniatin and beauvericin

scientific article

Interim analysis of a real-world precision medicine platform for molecular profiling of metastatic or advanced cancers: MONDTI

scientific article published on 17 July 2019

Intracellular protein binding patterns of the anticancer ruthenium drugs KP1019 and KP1339.

scientific article published on 11 March 2010

Intrathoracic solitary fibrous tumor - an international multicenter study on clinical outcome and novel circulating biomarkers

scientific article published on 2 October 2017

Intrinsic MDR-1 gene and P-glycoprotein expression in human melanoma cell lines.

scientific article published in December 1994

Intrinsic and Acquired Forms of Resistance against the Anticancer Ruthenium Compound KP1019 [Indazolium trans-[tetrachlorobis(1H-indazole)ruthenate (III)] (FFC14A)

scientific article published on 26 August 2004

Intrinsic fluorescence of the clinically approved multikinase inhibitor nintedanib reveals lysosomal sequestration as resistance mechanism in FGFR-driven lung cancer.

scientific article published on 7 September 2017

Irinotecan Upregulates Fibroblast Growth Factor Receptor 3 Expression in Colorectal Cancer Cells, Which Mitigates Irinotecan-Induced Apoptosis

scientific article

Is fibroblast growth factor receptor 4 a suitable target of cancer therapy?

scientific article

KP1019, a new redox-active anticancer agent--preclinical development and results of a clinical phase I study in tumor patients

scientific article published on October 2008

Ki67 index is an independent prognostic factor in epithelioid but not in non-epithelioid malignant pleural mesothelioma: a multicenter study

scientific article published on 29 January 2015

Lipid droplet-mediated scavenging as novel intrinsic and adaptive resistance factor against the multikinase inhibitor ponatinib

scientific article published on 16 February 2020

Long-Term Vemurafenib Exposure Induced Alterations of Cell Phenotypes in Melanoma: Increased Cell Migration and Its Association with EGFR Expression

scientific article published on 11 September 2019

Loss of CUL4A expression is underlying cisplatin hypersensitivity in colorectal carcinoma cells with acquired trabectedin resistance

scientific article published on 17 January 2017

Loss of phosphodiesterase 4D mediates acquired triapine resistance via Epac-Rap1-Integrin signaling.

scientific article published on 02 September 2016

Lysosomal Sequestration Impairs the Activity of the Preclinical FGFR Inhibitor PD173074

MET expression in melanoma correlates with a lymphangiogenic phenotype

scientific article published on 7 May 2012

Macromolecular Pt(IV) Prodrugs from Poly(organo)phosphazenes.

scientific article

Major vault protein supports glioblastoma survival and migration by upregulating the EGFR/PI3K signalling axis

scientific article

Maleimide-functionalised platinum(IV) complexes as a synthetic platform for targeted drug delivery.

scientific article published on March 2013

Mechanisms underlying reductant-induced reactive oxygen species formation by anticancer copper(II) compounds

scientific article

Metal Drugs and the Anticancer Immune Response

scientific article published on 29 November 2018

Metal drugs become targeted.

scientific article

Metal-Arene Complexes with Indolo[3,2-c]-quinolines: Effects of Ruthenium vs Osmium and Modifications of the Lactam Unit on Intermolecular Interactions, Anticancer Activity, Cell Cycle, and Cellular Accumulation

scientific article published on 17 January 2013

Metal-based paullones as putative CDK inhibitors for antitumor chemotherapy

scientific article published on 13 November 2007

Mouse tissue distribution and persistence of the food-born fusariotoxins Enniatin B and Beauvericin

scientific article

Multi-scale imaging of anticancer platinum(iv) compounds in murine tumor and kidney

scientific article published on 03 February 2016

Multidrug resistance markers P-glycoprotein, multidrug resistance protein 1, and lung resistance protein in non-small cell lung cancer: prognostic implications.

scientific article

Multidrug-resistant cancer cells are preferential targets of the new antineoplastic lanthanum compound KP772 (FFC24).

scientific article

Multiple chromosomal abnormalities in human liver (pre)neoplasia

scientific article published on 01 April 2004

Myeloid STAT3 promotes formation of colitis-associated colorectal cancer in mice

scientific article published on 22 January 2015

NKP-1339, a first-in-class anticancer drug showing mild side effects and activity in patients suffering from advanced refractory cancer.

scientific article published on 17 September 2012

Nanoformulation improves activity of the (pre)clinical anticancer ruthenium complex KP1019.

scientific article published on May 2014

Nanoformulations of anticancer FGFR inhibitors with improved therapeutic index

scientific article published on 16 August 2018

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

scientific article

New cellular tools reveal complex epithelial-mesenchymal interactions in hepatocarcinogenesis

scientific article

Nintedanib Is Active in Malignant Pleural Mesothelioma Cell Models and Inhibits Angiogenesis and Tumor Growth In Vivo

scientific article published on 03 May 2018

Novel inhibitors of cyclin-dependent kinases combat hepatocellular carcinoma without inducing chemoresistance.

scientific article published on 12 August 2013

Novel p53-dependent anticancer strategy by targeting iron signaling and BNIP3L-induced mitophagy.

scientific article published on 26 October 2015

Ophiobolin A induces paraptosis-like cell death in human glioblastoma cells by decreasing BKCa channel activity.

scientific article published on 28 March 2013

Ophiobolin A, a sesterterpenoid fungal phytotoxin, displays higher in vitro growth-inhibitory effects in mammalian than in plant cells and displays in vivo antitumor activity.

scientific article published on 10 June 2013

Opposing Roles of JNK and p38 in Lymphangiogenesis in Melanoma.

scientific article published on 29 January 2016

Organometallic anticancer complexes of lapachol: metal centre-dependent formation of reactive oxygen species and correlation with cytotoxicity

scientific article published on April 2013

Organometallic indolo[3,2-c]quinolines versus indolo[3,2-d]benzazepines: synthesis, structural and spectroscopic characterization, and biological efficacy

scientific article

Osmium(IV) complexes with 1H- and 2H-indazoles: tautomer identity versus spectroscopic properties and antiproliferative activity

scientific article

Overexpression of Aurora-A in primary cells interferes with S-phase entry by diminishing Cyclin D1 dependent activities

scientific article published on 16 March 2011

Overexpression of Hsp27 affects the metastatic phenotype of human melanoma cells in vitro

scientific article

Overexpression of Hsp27 in a human melanoma cell line: regulation of E-cadherin, MUC18/MCAM, and plasminogen activator (PA) system

scientific article

Overexpression of the human major vault protein in astrocytic brain tumor cells

scientific article

Oxidative stress and DNA interactions are not involved in Enniatin- and Beauvericin-mediated apoptosis induction

scientific article

P-glycoprotein regulates chemosensitivity in early developmental stages of the mouse

scientific article published in December 1993

P01.02FIBROBLAST GROWTH FACTOR 4 CONTRIBUTES TO 3-DIMENSIONAL GROWTH OF HUMAN GLIOBLASTOMA.

scientific article published in September 2014

P01.14PRESENCE OF A STEM CELL-LIKE CELL SUBPOPULATION IS ASSOCIATED WITH ENHANCED SURVIVAL OF GLIOBLASTOMA PATIENTS.

scientific article published in September 2014

P04.24MUTATIONS OF THE TERT PROMOTER CORRELATE WITH ENHANCED TELOMERASE ACTIVATION AND PREDICT A WORSE PROGNOSIS IN PRIMARY GLIOBLASTOMA PATIENTS.

scientific article published in September 2014

P33. Potential clinical relevance of in vitro migratory activity in malignant pleural mesothelioma.

scientific article published in October 2014

P34. Exploring cell plasticity in malignant pleural mesothelioma.

scientific article published in October 2014

P35. Fibroblast growth factor signals and their connection to micrornas in malignant pleural mesothelioma

scientific article published in October 2014

P36. The prognostic potential of circulating and tissue activin A level in malignant pleural mesothelioma.

scientific article published in October 2014

P44. Activin A is novel circulating biomarker in lung cancer.

scientific article

Pan-RAF and MEK vertical inhibition enhances therapeutic response in non-V600 BRAF mutant cells.

scientific article published on 8 May 2018

Podoplanin expression in primary brain tumors induces platelet aggregation and increases risk of venous thromboembolism.

scientific article published on 10 January 2017

Poly(lactic acid) nanoparticles of the lead anticancer ruthenium compound KP1019 and its surfactant-mediated activation

scientific article published on 29 October 2013

Possible role of the multidrug resistance-associated protein (MRP) in chemoresistance of human melanoma cells

scientific article published on March 1997

Post-digestion stabilization of osmium enables quantification by ICP-MS in cell culture and tissue

scientific article published on 01 June 2017

Preclinical studies on metal based anticancer drugs as enabled by integrated metallomics and metabolomics

scientific article published on 01 October 2019

Prenylation inhibition-induced cell death in melanoma: reduced sensitivity in BRAF mutant/PTEN wild-type melanoma cells

scientific article

Pretreatment serum C-reactive protein levels predict benefit from multimodality treatment including radical surgery in malignant pleural mesothelioma: a retrospective multicenter analysis

scientific article published in August 2012

Prognostic quality of activating TERT promoter mutations in glioblastoma: interaction with the rs2853669 polymorphism and patient age at diagnosis

scientific article

Prognostic significance of telomerase-associated parameters in glioblastoma: effect of patient age.

scientific article published on 7 February 2013

Promoter methylation patterns of ABCB1, ABCC1 and ABCG2 in human cancer cell lines, multidrug-resistant cell models and tumor, tumor-adjacent and tumor-distant tissues from breast cancer patients.

scientific article published on 28 September 2016

Promyelocytic HL60 cells express NADPH oxidase and are excellent targets in a rapid spectrophotometric microplate assay for extracellular superoxide

scientific article published on 26 September 2003

Quantitative bioimaging by LA-ICP-MS: a methodological study on the distribution of Pt and Ru in viscera originating from cisplatin- and KP1339-treated mice.

scientific article

Rapid generation of hydrogen peroxide contributes to the complex cell death induction by the angucycline antibiotic landomycin E.

scientific article published on 9 February 2017

Relevance of microRNA modulation in chemoresistant colon cancer in vitro.

scientific article

Resistance against novel anticancer metal compounds: differences and similarities

scientific article published on February 2008

Response of experimental malignant melanoma models to the pan-Aurora kinase inhibitor VE-465.

scientific article published in December 2010

Review of cancer treatment with immune checkpoint inhibitors : Current concepts, expectations, limitations and pitfalls.

scientific article published on 2 November 2017

Ribonucleotide reductase as one important target of [Tris(1,10-phenanthroline)lanthanum(III)] trithiocyanate (KP772).

scientific article

Ruthenium-arene complexes bearing naphthyl-substituted 1,3-dioxoindan-2-carboxamides ligands for G-quadruplex DNA recognition

scientific article published on 11 July 2019

SP-transcription factors are involved in basal MVP promoter activity and its stimulation by HDAC inhibitors

scientific article published on April 2004

Self-assembled Pt2L2 boxes strongly bind G-quadruplex DNA and influence gene expression in cancer cells

scientific article

Sensitivity of Melanoma Cells to EGFR and FGFR Activation but Not Inhibition is Influenced by Oncogenic BRAF and NRAS Mutations.

scientific article published on 9 March 2015

Sensitivity towards the GRP78 inhibitor KP1339/IT-139 is characterized by apoptosis induction via caspase 8 upon disruption of ER homeostasis.

scientific article published on 14 July 2017

Serum-binding properties of isosteric ruthenium and osmium anticancer agents elucidated by SEC-ICP-MS

scientific article published on 25 August 2018

Seven novel and stable translocations associated with oncogenic gene expression in malignant melanoma.

scientific article

Silencing of protein kinase D2 induces glioma cell senescence via p53-dependent and -independent pathways.

scientific article

Simultaneous blockade of the epidermal growth factor receptor/mammalian target of rapamycin pathway by epidermal growth factor receptor inhibitors and rapamycin results in reduced cell growth and survival in biliary tract cancer cells

scientific article

Spatio-temporally precise activation of engineered receptor tyrosine kinases by light.

scientific article

Specific antioxidant compounds differentially modulate cytotoxic activity of doxorubicin and cisplatin: in vitro and in vivo study

scientific article

Sphaeropsidin A shows promising activity against drug-resistant cancer cells by targeting regulatory volume increase

scientific article

Spheroid glioblastoma culture conditions as antigen source for dendritic cell-based immunotherapy: spheroid proteins are survival-relevant targets but can impair immunogenic interferon γ production

scientific article published on 08 April 2019

Stable protein expression in mammalian cells using baculoviruses.

scientific article published on January 2012

Stated response to increased enforcement density and penalty size for speeding and driving unbelted.

scientific article published on 18 April 2012

Structural simplification of bioactive natural products with multicomponent synthesis. 3. Fused uracil-containing heterocycles as novel topoisomerase-targeting agents

scientific article

Structure-Related Mode-of-Action Differences of Anticancer Organoruthenium Complexes with β-Diketonates

scientific article

Structure-activity relationships for ruthenium and osmium anticancer agents - towards clinical development

scientific article published on 24 November 2017

Subcellular Duplex DNA and G-Quadruplex Interaction Profiling of a Hexagonal PtII Metallacycle

scientific article published on 08 May 2019

Subtype-specific KRAS mutations in advanced lung adenocarcinoma: a retrospective study of patients treated with platinum-based chemotherapy

scientific article

Suppression of activin A signals inhibits growth of malignant pleural mesothelioma cells ⬇️

scientific article published on November 20, 2012

Synergistic anticancer activity of arsenic trioxide with erlotinib is based on inhibition of EGFR-mediated DNA double-strand break repair

scientific article published on 2 April 2013

Synergistic effect of Sorafenib and Sunitinib with Enzastaurin, a selective protein kinase C inhibitor in renal cell carcinoma cell lines

scientific article

Synergistic effects of erlotinib and everolimus on bronchial carcinoids and large-cell neuroendocrine carcinomas with activated EGFR/AKT/mTOR pathway

scientific article

Synthesis and biological evaluation of biotin-conjugated anticancer thiosemicarbazones and their iron(III) and copper(II) complexes

scientific article published on 19 October 2018

Synthesis and in vivo anticancer evaluation of poly(organo)phosphazene-based metallodrug conjugates.

scientific article

Synthesis, Characterization and in vitro Studies of a Cathepsin B-Cleavable Prodrug of the VEGFR Inhibitor Sunitinib

scientific article published on 19 December 2018

TERT expression is susceptible to BRAF and ETS-factor inhibition in BRAFV600E/TERT promoter double-mutated glioma

scientific article published on 07 August 2019

TERT promoter mutations are associated with poor prognosis and cell immortalization in meningioma

scientific article published on 01 November 2018

THE ROLE OF REACTIVE OXYGEN SPECIES IN TUMOR CELLS APOPTOSIS INDUCED BY LANDOMYCIN A.

scientific article published in September 2015

Targeted proteolysis of plectin isoform 1a accounts for hemidesmosome dysfunction in mice mimicking the dominant skin blistering disease EBS-Ogna

scientific article (publication date: December 2011)

Targeting a Targeted Drug: An Approach Toward Hypoxia-Activatable Tyrosine Kinase Inhibitor Prodrugs.

scientific article published on 5 October 2016

Targeting fibroblast-growth-factor-receptor-dependent signaling for cancer therapy.

scientific article published on 07 March 2011

Telomerase activation in posterior fossa group A ependymomas is associated with dismal prognosis and chromosome 1q gain

scientific article

Telomerase reverse transcriptase promoter mutations identify a genomically defined and highly aggressive human pleural mesothelioma subgroup

scientific article published on 21 April 2020

Telomerase- and alternative telomere lengthening-independent telomere stabilization in a metastasis-derived human non-small cell lung cancer cell line: effect of ectopic hTERT.

scientific article published on April 2006

Temozolomide-induced modification of the CXC chemokine network in experimental gliomas ⬇️

scientific article published on March 8, 2011

Temsirolimus inhibits malignant pleural mesothelioma growth in vitro and in vivo: synergism with chemotherapy

scientific article

The FAK inhibitor BI 853520 inhibits spheroid formation and orthotopic tumor growth in malignant pleural mesothelioma

scientific article published on 11 December 2018

The First Anticancer Tris(pyrazolyl)borate Molybdenum(IV) Complexes: Tested in Vitro and in Vivo-A Comparison of O,O-, S,O-, and N,N-Chelate Effects

scientific article published on 19 November 2019

The Multi-Stimulus Box: an innovative learning device for the comparative study of object perception and recognition with various types of stimuli

scientific article published in September 2012

The Natural Fungal Metabolite Beauvericin Exerts Anticancer Activity In Vivo: A Pre-Clinical Pilot Study.

scientific article published on 24 August 2017

The PI3 kinase/mTOR blocker NVP-BEZ235 overrides resistance against irreversible ErbB inhibitors in breast cancer cells.

scientific article published on 3 November 2010

The activin axis in liver biology and disease.

scientific article published on 25 September 2006

The gallium complex KP46 exerts strong activity against primary explanted melanoma cells and induces apoptosis in melanoma cell lines

scientific article

The influence of valerian treatment on "reaction time, alertness and concentration" in volunteers

scientific article

The major vault protein is responsive to and interferes with interferon-gamma-mediated STAT1 signals

scientific article published on 17 January 2006

The major vault protein mediates resistance to epidermal growth factor receptor inhibition in human hepatoma cells

scientific article published on 17 January 2012

The metastatic microenvironment: Claudin-1 suppresses the malignant phenotype of melanoma brain metastasis.

scientific article

The naturally born fusariotoxin enniatin B and sorafenib exert synergistic activity against cervical cancer in vitro and in vivo.

scientific article

The plasma membrane Ca2+ pump PMCA4b inhibits the migratory and metastatic activity of BRAF mutant melanoma cells.

scientific article

The ruthenium compound KP1339 potentiates the anticancer activity of sorafenib in vitro and in vivo

scientific article published on 18 June 2013

The thiosemicarbazone MeNNMe induces paraptosis by disrupting the ER thiol redox homeostasis based on protein disulfide isomerase inhibition

scientific article published on 15 October 2018

Thermodynamic Genome-Scale Metabolic Modeling of Metallodrug Resistance in Colorectal Cancer

scientific article published in 2021

Thiosemicarbazone Derivatives Developed to Overcome COTI-2 Resistance

scientific article published in 2022

Trabectedin Is Active against Malignant Pleural Mesothelioma Cell and Xenograft Models and Synergizes with Chemotherapy and Bcl-2 Inhibition In Vitro

scientific article published on 10 August 2016

Trabectedin has promising antineoplastic activity in high-grade meningioma

scientific article published on 5 March 2012

Triapine and a more potent dimethyl derivative induce endoplasmic reticulum stress in cancer cells.

scientific article published on 30 December 2013

Triapine-mediated ABCB1 induction via PKC induces widespread therapy unresponsiveness but is not underlying acquired triapine resistance.

scientific article

Trivanillic polyphenols with anticancer cytostatic effects through the targeting of multiple kinases and intracellular Ca2+ release

scientific article published on July 2012

Tumor microenvironment in focus: LA-ICP-MS bioimaging of a preclinical tumor model upon treatment with platinum(IV)-based anticancer agents.

scientific article published on 9 April 2015

Tumor-targeting of EGFR inhibitors by hypoxia-mediated activation

scientific article published on 30 July 2014

Unsymmetric mono- and dinuclear platinum(IV) complexes featuring an ethylene glycol moiety: synthesis, characterization, and biological activity

scientific article published on 17 December 2012

Up-regulation of 12(S)-lipoxygenase induces a migratory phenotype in colorectal cancer cells ⬇️

scientific article published on December 29, 2011

Up-regulation of the fibroblast growth factor 8 subfamily in human hepatocellular carcinoma for cell survival and neoangiogenesis.

scientific article published on 11 February 2011

Vaults and the major vault protein: novel roles in signal pathway regulation and immunity

scientific article

Vemurafenib resistance signature by proteome analysis offers new strategies and rational therapeutic concepts.

scientific article

Water-Soluble, Biocompatible Polyphosphazenes with Controllable and pH-Promoted Degradation Behavior

scientific article

Water-soluble cationic derivatives of indirubin, the active anticancer component from Indigo naturalis

scientific article

Whole genome amplification for CGH analysis: Linker-adapter PCR as the method of choice for difficult and limited samples

scientific article published on September 2004

Wnt1 is anti-lymphangiogenic in a melanoma mouse model

scientific article

X-ray absorption near edge structure spectroscopy to resolve the in vivo chemistry of the redox-active indazolium trans-[Tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019).

scientific article published on 31 January 2013

[11C]Erlotinib PET cannot detect acquired erlotinib resistance in NSCLC tumor xenografts in mice.

scientific article

p53 Loss Mediates Hypersensitivity to ETS Transcription Factor Inhibition Based on PARylation-Mediated Cell Death Induction

scientific article published on 30 October 2020

{(1R,2R,4R)-4-methyl-1,2-cyclohexanediamine}oxalatoplatinum(II): a novel enantiomerically pure oxaliplatin derivative showing improved anticancer activity in vivo

scientific article

{Ru(CO)x}-Core complexes with benzimidazole ligands: synthesis, X-ray structure and evaluation of anticancer activity in vivo.

scientific article published on 16 February 2017

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