List of works by Samuel M. Meier

Am(m)ines make the difference: organoruthenium am(m)ine complexes and their chemistry in anticancer drug development

scientific article published on 22 January 2013

An Organoruthenium Anticancer Agent Shows Unexpected Target Selectivity For Plectin.

scientific article published on 26 May 2017

Application of mass spectrometric techniques to delineate the modes-of-action of anticancer metallodrugs

scientific article published on July 2013

Aquaporins in cancer development: opportunities for bioinorganic chemistry to contribute novel chemical probes and therapeutic agents.

scientific article

Aqueous chemistry and antiproliferative activity of a pyrone-based phosphoramidate Ru(arene) anticancer agent.

scientific article

Bioimaging of isosteric osmium and ruthenium anticancer agents by LA-ICP-MS.

scientific article published on 7 March 2018

Biomolecule binding vs. anticancer activity: Reactions of Ru(arene)[(thio)pyr-(id)one] compounds with amino acids and proteins

scientific article published on 26 August 2011

Bulky N(,N)-(di)alkylethane-1,2-diamineplatinum(II) compounds as precursors for generating unsymmetrically substituted platinum(IV) complexes.

scientific article published on 21 June 2013

Capillary zone electrophoresis and capillary zone electrophoresis–electrospray ionization mass spectrometry studies on the behavior of anticancer cis- and trans-[dihalidobis(2-propanone oxime)platinum(II)] complexes in aqueous solutions

scientific article published on 28 July 2012

Characterizing activation mechanisms and binding preferences of ruthenium metallo-prodrugs by a competitive binding assay.

scientific article

Combined Proteome and Eicosanoid Profiling Approach for Revealing Implications of Human Fibroblasts in Chronic Inflammation

scientific article published on 20 January 2017

DNA or protein? Capillary zone electrophoresis-mass spectrometry rapidly elucidates metallodrug binding selectivity

scientific article

Daily Caffeine Intake Induces Concentration-Dependent Medial Temporal Plasticity in Humans: A Multimodal Double-Blind Randomized Controlled Trial

scientific article

Design Strategies and Medicinal Applications of Metal-Peptidic Bioconjugates

scientific article published on 03 April 2020

Dicopper(II) and dizinc(II) complexes with nonsymmetric dinucleating ligands based on indolo[3,2-c]quinolines: synthesis, structure, cytotoxicity, and intracellular distribution.

scientific article published on 16 August 2013

Dual Triggering of DNA Binding and Fluorescence via Photoactivation of a Dinuclear Ruthenium(II) Arene Complex

scientific article published on 12 May 2007

Efficiently Detecting Metallodrug-Protein Adducts: Ion Trap versus Time-of-Flight Mass Analyzers

scientific article published on 18 March 2014

Fragmentation methods on the balance: unambiguous top–down mass spectrometric characterization of oxaliplatin–ubiquitin binding sites

scientific article published on 08 November 2011

From hydrolytically labile to hydrolytically stable Ru(II)-arene anticancer complexes with carbohydrate-derived co-ligands.

scientific article published on 14 October 2010

Half-sandwich ruthenium(II) biotin conjugates as biological vectors to cancer cells

scientific article

Heteropentanuclear Oxalato-Bridged nd-4f (n=4, 5) Metal Complexes with NO Ligand: Synthesis, Crystal Structures, Aqueous Stability and Antiproliferative Activity

scientific article published on 10 August 2015

Identification of the structural determinants for anticancer activity of a ruthenium arene peptide conjugate

scientific article published on 27 May 2013

Influence of the π-coordinated arene on the anticancer activity of ruthenium(II) carbohydrate organometallic complexes

scientific article

Is the reactivity of M(II)-arene complexes of 3-hydroxy-2(1H)-pyridones to biomolecules the anticancer activity determining parameter?

scientific article published on September 2010

New Variations on the Theme of Gold(III) C∧N∧N Cyclometalated Complexes as Anticancer Agents: Synthesis and Biological Characterization

scientific article published on 20 November 2018

Novel metal(ii) arene 2-pyridinecarbothioamides: a rationale to orally active organometallic anticancer agents

On the binding modes of metal NHC complexes with DNA secondary structures: implications for therapy and imaging

scientific article published on 27 June 2017

Organometallic anticancer complexes of lapachol: metal centre-dependent formation of reactive oxygen species and correlation with cytotoxicity

scientific article published on April 2013

Plecstatin-1 induces an immunogenic cell death signature in colorectal tumour spheroids

scientific article published on 09 December 2020

Poly(lactic acid) nanoparticles of the lead anticancer ruthenium compound KP1019 and its surfactant-mediated activation

scientific article published on 29 October 2013

Post-digestion stabilization of osmium enables quantification by ICP-MS in cell culture and tissue

scientific article published on 01 June 2017

Protein ruthenation and DNA alkylation: chlorambucil-functionalized RAPTA complexes and their anticancer activity

scientific article published in February 2015

Proteomic and Metabolomic Analyses Reveal Contrasting Anti-Inflammatory Effects of an Extract of Mucor Racemosus Secondary Metabolites Compared to Dexamethasone

scientific article

Pyrone derivatives and metals: From natural products to metal-based drugs

Response Profiling Using Shotgun Proteomics Enables Global Metallodrug Mechanisms of Action To Be Established.

scientific article published on 7 November 2016

Rollover Cyclometalated Bipyridine Platinum Complexes as Potent Anticancer Agents: Impact of the Ancillary Ligands on the Mode of Action

scientific article published on 14 February 2018

Ruthenium-nitrosyl complexes with glycine, L-alanine, L-valine, L-proline, D-proline, L-serine, L-threonine, and L-tyrosine: synthesis, X-ray diffraction structures, spectroscopic and electrochemical properties, and antiproliferative activity

scientific article published on 20 February 2014

Selective targeting of PARP-1 zinc finger recognition domains with Au(iii) organometallics.

scientific article published on 2 January 2018

Sensing of Proteins by ICD Response of Iron(II) Clathrochelates Functionalized by Carboxyalkylsulfide Groups

scientific article published on 26 November 2020

Serum-binding properties of isosteric ruthenium and osmium anticancer agents elucidated by SEC-ICP-MS

scientific article published on 25 August 2018

Striking difference in antiproliferative activity of ruthenium- and osmium-nitrosyl complexes with azole heterocycles

scientific article

Structure-activity relationships for ruthenium and osmium anticancer agents - towards clinical development

scientific article published on 24 November 2017

Target profiling of an antimetastatic RAPTA agent by chemical proteomics: relevance to the mode of action

scientific article published on 9 February 2015

The metalation of hen egg white lysozyme impacts protein stability as shown by ion mobility mass spectrometry, differential scanning calorimetry, and X-ray crystallography

scientific article published on 31 March 2017

Time-dependent shotgun proteomics revealed distinct effects of an organoruthenium prodrug and its activation product on colon carcinoma cells

scientific article published on 01 January 2019

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