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List of works by Najoua Lalaoui

'Did He Who Made the Lamb Make Thee?' New Developments in Treating the 'Fearful Symmetry' of Acute Myeloid Leukemia

scientific article published on 11 February 2017

Antagonism of IAPs Enhances CAR T-cell Efficacy

scientific article published on 16 January 2019

Autophagy and AML--food for thought.

scientific article

Chemotherapy overcomes TRAIL-R4-mediated TRAIL resistance at the DISC level

scientific article

Colony-stimulating factor-1-induced oscillations in phosphatidylinositol-3 kinase/AKT are required for caspase activation in monocytes undergoing differentiation into macrophages

scientific article published on 31 August 2009

Combination of IAP antagonist and IFNγ activates novel caspase-10- and RIPK1-dependent cell death pathways.

scientific article published on 20 January 2017

Death Receptor-Induced Apoptosis Signalling Regulation by Ezrin Is Cell Type Dependent and Occurs in a DISC-Independent Manner in Colon Cancer Cells

scientific article published on 26 May 2015

Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2.

scientific article

Dynamics of HPV16 DNA load reflect the natural history of cervical HPV-associated lesions

scientific article

Functionally distinct roles for different miR-155 expression levels through contrasting effects on gene expression, in acute myeloid leukaemia

scientific article published on 14 October 2016

Inhibitor of Apoptosis Proteins (IAPs) Limit RIPK1-Mediated Skin Inflammation

scientific article published on 21 June 2017

Jekyll & Hyde: The Other Life of the Death Ligand TRAIL.

scientific article published in February 2017

Linear ubiquitin chain assembly complex coordinates late thymic T-cell differentiation and regulatory T-cell homeostasis

scientific article published on 18 November 2016

MK2 Inhibition Induces p53-Dependent Senescence in Glioblastoma Cells

scientific article published on 11 March 2020

MK2 Phosphorylates RIPK1 to Prevent TNF-Induced Cell Death

scientific article

MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis

scientific article published on 19 June 2020

Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease

scientific article published on 11 December 2019

P53-mediated upregulation of DcR1 impairs oxaliplatin/TRAIL-induced synergistic anti-tumour potential in colon cancer cells

scientific article

PD-L1 and IAPs co-operate to protect tumors from cytotoxic lymphocyte-derived TNF.

scientific article published on 30 June 2017

Quercetin-mediated Mcl-1 and survivin downregulation restores TRAIL-induced apoptosis in non-Hodgkin's lymphoma B cells

scientific article published on 20 September 2011

RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis

scientific article published on 8 May 2014

Recent advances in understanding inhibitor of apoptosis proteins

Relevance of necroptosis in cancer

scientific article published on 6 December 2016

Synergistic action of the MCL-1 inhibitor S63845 with current therapies in preclinical models of triple-negative and HER2-amplified breast cancer

scientific article published in August 2017

TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice.

scientific article

TRAIL in cancer therapy: present and future challenges

scientific article

TRAIL-R4 promotes tumor growth and resistance to apoptosis in cervical carcinoma HeLa cells through AKT

scientific article

Tankyrase-mediated ADP-ribosylation is a regulator of TNF-induced death

scientific article published on 11 May 2022

Targeting p38 or MK2 Enhances the Anti-Leukemic Activity of Smac-Mimetics.

scientific article published in February 2016

Targeting triple-negative breast cancers with the Smac-mimetic birinapant

scientific article published on 27 April 2020

The Pseudokinase MLKL and the Kinase RIPK3 Have Distinct Roles in Autoimmune Disease Caused by Loss of Death-Receptor-Induced Apoptosis

scientific article

The TNF Receptor Superfamily-NF-κB Axis Is Critical to Maintain Effector Regulatory T Cells in Lymphoid and Non-lymphoid Tissues

scientific article published on 4 September 2017

The caspase-8 inhibitor emricasan combines with the SMAC mimetic birinapant to induce necroptosis and treat acute myeloid leukemia

scientific article

The molecular relationships between apoptosis, autophagy and necroptosis

scientific article

The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism

scientific article

Tumor immune evasion arises through loss of TNF sensitivity

scientific article published on 01 May 2018

Viral MLKL Homologs Subvert Necroptotic Cell Death by Sequestering Cellular RIPK3

scientific article published on 01 September 2019

cIAPs and XIAP regulate myelopoiesis through cytokine production in an RIPK1- and RIPK3-dependent manner

scientific article published on 04 February 2014

dsRNA induces apoptosis through an atypical death complex associating TLR3 to caspase-8.

scientific article

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