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List of works by Sean Emery

A Randomized Study of Pharmacokinetics, Efficacy, and Safety of 2 Raltegravir Plus Atazanavir Strategies in ART-Treated Adults

article

A comparison of computational models with and without genotyping for prediction of response to second-line HIV therapy.

scientific article published on 15 April 2014

A comparison of three computational modelling methods for the prediction of virological response to combination HIV therapy

scientific article

A novel chemokine-receptor-5 (CCR5) blocker, SCH532706, has differential effects on CCR5+CD4+ and CCR5+CD8+ T cell numbers in chronic HIV infection

scientific article published on June 2010

A phase I study of the pharmacokinetics and safety of passive immunotherapy with caprine anti-HIV antibodies, (PE)HRG214, in HIV-1-infected individuals

scientific article

A randomised trial comparing genotypic and virtual phenotypic interpretation of HIV drug resistance: the CREST study

scientific article

A randomised trial of subcutaneous intermittent interleukin-2 without antiretroviral therapy in HIV-infected patients: the UK-Vanguard Study

scientific article

A randomised, open-label comparison of three highly active antiretroviral therapy regimens including two nucleoside analogues and indinavir for previously untreated HIV-1 infection: the OzCombo1 study

article

A randomized factorial trial comparing 4 treatment regimens in treatment-naive HIV-infected persons with AIDS and/or a CD4 cell count <200 cells/μL in South Africa

scientific article

A randomized, controlled 24-week study of intermittent subcutaneous interleukin-2 in HIV-1 infected patients in Thailand

article

A randomized, placebo-controlled phase I trial of DNA prime, recombinant fowlpox virus boost prophylactic vaccine for HIV-1.

scientific article published in January 2006

Abacavir does not affect circulating levels of inflammatory or coagulopathic biomarkers in suppressed HIV: a randomized clinical trial

scientific article published on November 2010

An HIV-1 clade A/E DNA prime, recombinant fowlpox virus boost vaccine is safe, but non-immunogenic in a randomized phase I/IIa trial in Thai volunteers at low risk of HIV infection

scientific article published in October 2010

An objective case definition of lipodystrophy in HIV-infected adults: a case-control study

scientific article published in March 2003

An update to the HIV-TRePS system: the development of new computational models that do not require a genotype to predict HIV treatment outcomes

scientific article

Antiretroviral Resistance After First-Line Antiretroviral Therapy Failure in Diverse HIV-1 Subtypes in the SECOND-LINE Study

scientific article published on 26 June 2016

Antiretroviral agents: Focus on Maraviroc for the Treatment of HIV-1-Infected Adults

article

Antiretroviral roll-out: the problem of second-line therapy

scientific article published on July 2009

Assessing site performance in the Altair study, a multinational clinical trial

scientific article published on 8 April 2015

Associations between vitamin D metabolites, antiretroviral therapy and bone mineral density in people with HIV.

scientific article

Atazanavir trough plasma concentration monitoring in a cohort of HIV-1-positive individuals receiving highly active antiretroviral therapy

scientific article published on 4 July 2005

Baseline HIV-1 resistance, virological outcomes, and emergent resistance in the SECOND-LINE trial: an exploratory analysis.

scientific article published on 20 January 2015

Biomarkers and bacterial pneumonia risk in patients with treated HIV infection: a case-control study

scientific article

Body composition and metabolic outcomes after 96 weeks of treatment with ritonavir-boosted lopinavir plus either nucleoside or nucleotide reverse transcriptase inhibitors or raltegravir in patients with HIV with virological failure of a standard fir

scientific article published in November 2016

Bone mineral density in HIV participants randomized to raltegravir and lopinavir/ritonavir compared with standard second line therapy

scientific article published on September 2013

CD4 cell response to 3 doses of subcutaneous interleukin 2: meta-analysis of 3 Vanguard studies

scientific article published on 14 June 2004

Cerebrospinal fluid exposure of efavirenz and its major metabolites when dosed at 400 mg and 600 mg once daily: a randomized controlled trial

scientific article published on 11 December 2014

Changes in bone turnover and bone loss in HIV-infected patients changing treatment to tenofovir-emtricitabine or abacavir-lamivudine

scientific article (publication date: 2012)

Changes in plasma lipidome following initiation of antiretroviral therapy

scientific article published in PLoS ONE

Chemokine receptor genotype and response to interleukin-2 therapy in HIV-1-infected individuals

article

Circulating microRNAs in Sera Correlate with Soluble Biomarkers of Immune Activation but Do Not Predict Mortality in ART Treated Individuals with HIV-1 Infection: A Case Control Study

scientific article published on 14 October 2015

Clinical trials of antiretroviral therapy in developing countries

scientific article published on 01 February 2000

Combined analysis of two-year follow-up from two open-label randomized trials comparing efficacy of three nucleoside reverse transcriptase inhibitor backbones for previously untreated HIV-1 infection: OzCombo 1 and 2.

scientific article published in July 2003

Comprehensive Pharmacokinetic, Pharmacodynamic and Pharmacogenetic Evaluation of Once-Daily Efavirenz 400 and 600 mg in Treatment-Naïve HIV-Infected Patients at 96 Weeks: Results of the ENCORE1 Study

scientific article published on 29 December 2015

Computational models as predictors of HIV treatment outcomes for the Phidisa cohort in South Africa

scientific article

Considerations in the rationale, design and methods of the Strategic Timing of AntiRetroviral Treatment (START) study

scientific article published on 30 April 2012

Demographic and HIV-specific characteristics of participants enrolled in the INSIGHT Strategic Timing of AntiRetroviral Treatment (START) trial

scientific article

Determination of clinically relevant cutoffs for HIV-1 phenotypic resistance estimates through a combined analysis of clinical trial and cohort data

scientific article

Differences in the direction of change of cerebral function parameters are evident over three years in HIV-infected individuals electively commencing initial cART.

scientific article published on 27 February 2015

Disease Progression and Fatal Outcomes in HIV‐Infected Patients during Interruption of Antiretroviral Treatment

article

Does choice of combination antiretroviral therapy (cART) alter changes in cerebral function testing after 48 weeks in treatment-naive, HIV-1-infected individuals commencing cART? A randomized, controlled study.

scientific article

Dynamics of cognitive change in HIV-infected individuals commencing three different initial antiretroviral regimens: a randomized, controlled study

article

Early antiretroviral therapy with raltegravir generates sustained reductions in HIV reservoirs but not lower T-cell activation levels

scientific article published on May 2015

Efavirenz plasma concentrations did not predict cessation of therapy due to neuropsychiatric symptoms in a large randomized trial

scientific article published in October 2009

Efavirenz versus Boosted Atazanavir or Zidovudine and Abacavir in Antiretroviral Treatment–Naive, HIV‐Infected Subjects: Week 48 Data from the Altair Study ⬇️

scientific article published on October 1, 2010

Effect of nucleoside reverse transcriptase inhibitors on CD4 T-cell recovery in HIV-1-infected individuals receiving long-term fully suppressive combination antiretroviral therapy.

scientific article

Effect of rosiglitazone on peroxisome proliferator-activated receptor gamma gene expression in human adipose tissue is limited by antiretroviral drug-induced mitochondrial dysfunction

scientific article published in December 2008

Effects of IL-2 therapy in asymptomatic HIV-infected individuals on proliferative responses to mitogens, recall antigens and HIV-related antigens

scientific article

Effects of alpha-tocopherol on carbon tetrachloride metabolism in rat liver microsomes.

scientific article published on January 1987

Efficacy and safety of efavirenz 400 mg daily versus 600 mg daily: 96-week data from the randomised, double-blind, placebo-controlled, non-inferiority ENCORE1 study

scientific article published on 12 April 2015

Evaluation in macaques of HIV-1 DNA vaccines containing primate CpG motifs and fowlpoxvirus vaccines co-expressing IFN? or IL-12

article

Evaluation of ultrasound for assessing facial lipoatrophy in a randomized, placebo-controlled trial

scientific article published in August 2005

Evolution of CD4+ T cell count in HIV-1-infected adults receiving antiretroviral therapy with sustained long-term virological suppression

scientific article published in June 2009

HIV DNA subspecies persist in both activated and resting memory CD4+ T cells during antiretroviral therapy

scientific article published on 08 January 2014

HIV disease progression in a patient cohort treated via a clinical research network in a resource limited setting

article

HIV lipodystrophy in participants randomised to lopinavir/ritonavir (LPV/r) +2-3 nucleoside/nucleotide reverse transcriptase inhibitors (N(t)RTI) or LPV/r + raltegravir as second-line antiretroviral therapy

scientific article published on 30 October 2013

HLA alleles association with changes in bone mineral density in HIV-1-infected adults changing treatment to tenofovir-emtricitabine or abacavir-lamivudine

scientific article

High levels of human antigen-specific CD4+ T cells in peripheral blood revealed by stimulated coexpression of CD25 and CD134 (OX40).

scientific article published on 27 July 2009

Hip structural parameters over 96 weeks in HIV-infected adults switching treatment to tenofovir-emtricitabine or abacavir-lamivudine

scientific article

Immune reconstitution in HIV infection

article

Immune-based therapies in HIV infection

article

Immunodeficiency and the risk of serious clinical endpoints in a well studied cohort of treated HIV-infected patients

scientific article

Immunomodulators as adjunctive therapy for HIV-1 infection

article

Impact of lamivudine on HIV and hepatitis B virus-related outcomes in HIV/hepatitis B virus individuals in a randomized clinical trial of antiretroviral therapy in southern Africa ⬇️

scientific article published on September 10, 2011

Impact of treatment with raltegravir during primary or chronic HIV infection on RNA decay characteristics and the HIV viral reservoir

scientific article published in November 2011

Improved quality of life with immediate versus deferred initiation of antiretroviral therapy in early asymptomatic HIV infection

scientific article published on 24 January 2017

In vivo, nucleoside reverse-transcriptase inhibitors alter expression of both mitochondrial and lipid metabolism genes in the absence of depletion of mitochondrial DNA.

scientific article published on 12 April 2005

Inferior clinical outcome of the CD4+ cell count-guided antiretroviral treatment interruption strategy in the SMART study: role of CD4+ Cell counts and HIV RNA levels during follow-up

scientific article published in April 2008

Initiation of Antiretroviral Therapy in Early Asymptomatic HIV Infection

scientific article

Integrated HIV DNA accumulates prior to treatment while episomal HIV DNA records ongoing transmission afterwards

scientific article published in March 2012

Intensification of antiretroviral therapy with raltegravir or addition of hyperimmune bovine colostrum in HIV-infected patients with suboptimal CD4+ T-cell response: a randomized controlled trial

scientific article published on 19 September 2011

Lipid profiles in HIV-infected adults receiving atazanavir and atazanavir/ritonavir: systematic review and meta-analysis of randomized controlled trials

scientific article published on 16 June 2010

Lipodystrophy following antiretroviral therapy of primary HIV infection

article

Low-dose versus standard-dose ritonavir-boosted atazanavir in virologically suppressed Thai adults with HIV (LASA): a randomised, open-label, non-inferiority trial

scientific article published on 24 May 2016

Major clinical outcomes in antiretroviral therapy (ART)-naive participants and in those not receiving ART at baseline in the SMART study

scientific article

Maraviroc, as a Switch Option, in HIV-1-infected Individuals With Stable, Well-controlled HIV Replication and R5-tropic Virus on Their First Nucleoside/Nucleotide Reverse Transcriptase Inhibitor Plus Ritonavir-boosted Protease Inhibitor Regimen: Wee

scientific article published on 5 April 2016

Metabolic disorders and cardiovascular consequences of  HIV infection and antiretroviral  therapy

scientific article published on July 2009

Minor changes in calculated creatinine clearance and anion-gap are associated with tenofovir disoproxil fumarate-containing highly active antiretroviral therapy

scientific article published in March 2006

Nadir CD4 count and monthly income predict cervical squamous cell abnormalities in HIV-positive women in a resource-limited setting

scientific article published in August 2008

No effect of rosiglitazone for treatment of HIV-1 lipoatrophy: randomised, double-blind, placebo-controlled trial.

scientific article published in February 2004

Outpatient Continuous Intravenous Interleukin‐2 or Subcutaneous, Polyethylene Glycol‐Modified Interleukin‐2 in Human Immunodeficiency Virus‐Infected Patients: A Randomized, Controlled, Multicenter Study ⬇️

scientific article published on October 1, 1998

Pharmacokinetic and Pharmacodynamic Comparison of Once-Daily Efavirenz (400 mg vs. 600 mg) in Treatment-Naïve HIV-Infected Patients: Results of the ENCORE1 Study

scientific article published on 5 June 2015

Pharmacokinetics of lamivudine and lamivudine-triphosphate after administration of 300 milligrams and 150 milligrams once daily to healthy volunteers: results of the ENCORE 2 study

scientific article published on 19 December 2011

Pharmacokinetics of plasma lopinavir/ritonavir following the administration of 400/100 mg, 200/150 mg and 200/50 mg twice daily in HIV-negative volunteers

scientific article published on 17 December 2010

Plasma levels of soluble CD14 independently predict mortality in HIV infection

scientific article

Poly-l-lactic acid for HIV-1 facial lipoatrophy: 48-week follow-up

scientific article published in March 2009

Pre-therapy inflammation and coagulation activation and long-term CD4 count responses to the initiation of antiretroviral therapy

scientific article published on 11 May 2015

Predicting the potential benefits of early initiation of ART: time to do a trial to find out

Predictors of bacterial pneumonia in Evaluation of Subcutaneous Interleukin-2 in a Randomized International Trial (ESPRIT).

scientific article published on 31 August 2010

Predictors of clinical progression in HIV-1-infected adults initiating combination antiretroviral therapy with advanced disease in the Asia-Pacific region: results from the TREAT Asia HIV observational database

scientific article published on 19 February 2013

Predictors of limb fat gain in HIV positive patients following a change to tenofovir-emtricitabine or abacavir-lamivudine

scientific article (publication date: 2011)

Project Phidisa: development of clinical research capacity within the South African National Defence Force

scientific article published on January 2007

Pulmonary effects of immediate versus deferred antiretroviral therapy in HIV-positive individuals: a nested substudy within the multicentre, international, randomised, controlled Strategic Timing of Antiretroviral Treatment (START) trial

scientific article published on 20 October 2016

Raltegravir non-inferior to nucleoside based regimens in second-line therapy with lopinavir/ritonavir over 96 weeks: a randomised open label study for the treatment of HIV-1 infection

scientific article published in 2015

Raltegravir: a new choice in HIV and new chances for research

scientific article published on 3 August 2009

Reply

scientific article published in 2001

Reply to "Issues on results of the external quality assessment for proviral DNA testing of HIV-1 Tropism in the Maraviroc Switch collaborative study".

scientific article published on December 2013

Results of external quality assessment for proviral DNA testing of HIV tropism in the Maraviroc Switch collaborative study

scientific article published on 17 April 2013

Safety and immunogenicity of UBI HIV-1MN octameric V3 peptide vaccine administered by subcutaneous injection.

scientific article

Selective exclusion of treatment arms in multi-arm randomized clinical trials

Short Communication: Nonnucleoside Reverse Transcriptase Inhibitor Fold Change or Plasma Concentration as a Predictor of Virological Response over 48 Weeks in Highly Treatment Experienced HIV-Positive Individuals

article

Short communication: HIV blips while on antiretroviral therapy can indicate consistently detectable viral levels due to assay underreporting

scientific article published on 09 August 2013

Simplification of antiretroviral therapy with tenofovir-emtricitabine or abacavir-Lamivudine: a randomized, 96-week trial

scientific article published in November 2009

Soluble biomarkers and morbidity and mortality among people infected with HIV: summary of published reports from 1997 to 2010

scientific article

Substantial improvements in performance indicators achieved in a peripheral blood mononuclear cell cryopreservation quality assurance program using single donor samples

scientific article published on 18 October 2006

The Safety, Efficacy, and Pharmacokinetic Profile of a Switch in Antiretroviral Therapy to Saquinavir, Ritonavir, and Atazanavir Alone for 48 Weeks and a Switch in the Saquinavir Formulation

scientific article published in 2007

The development of an expert system to predict virological response to HIV therapy as part of an online treatment support tool

scientific article published in September 2011

The effect of cimetidine and ranitidine on paracetamol glucuronidation and sulphation in cultured rat hepatocytes

scientific article published on 01 May 1985

The evaluation of subcutaneous proleukin (interleukin-2) in a randomized international trial: rationale, design, and methods of ESPRIT.

scientific article published in April 2002

The impact of registration of clinical trials units: the UK experience

scientific article

The influence of HLA supertype on thymidine analogue associated with low peripheral fat in HIV.

scientific article published in November 2012

The normalized inhibitory quotient of boosted protease inhibitors is predictive of viral load response in treatment-experienced HIV-1-infected individuals

scientific article published in September 2005

The potential cost and benefits of raltegravir in simplified second-line therapy among HIV infected patients in Nigeria and South Africa

scientific article published on 15 February 2013

The search for an HIV cure: tackling latent infection

scientific article published on 05 March 2013

Therapeutic Strategies for HIV Infection — Time to Think Hard

article

Therapeutic vaccination against HIV: current progress and future possibilities

scientific article

Three-year durability of dual-nucleoside versus triple-nucleoside therapy in a Thai population with HIV infection

scientific article

Two patterns of cerebral metabolite abnormalities are detected on proton magnetic resonance spectroscopy in HIV-infected subjects commencing antiretroviral therapy.

scientific article

Vaccine-induced IgG2 anti-HIV p24 is associated with control of HIV in patients with a ‘high-affinity’ FcγRIIa genotype

article

Viral resuppression and detection of drug resistance following interruption of a suppressive non-nucleoside reverse transcriptase inhibitor-based regimen

scientific article

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