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List of works by Giovanni Luca Gravina

5-Azacitidine restores and amplifies the bicalutamide response on preclinical models of androgen receptor expressing or deficient prostate tumors

scientific article published on August 2010

A Letter to the Editor on the Article by Burri et al

scientific article published on 01 June 2010

A feasibility study of percutaneous Radiofrequency Ablation followed by Radiotherapy in the management of painful osteolytic bone metastases

scientific article

Additive antitumor effects of the epidermal growth factor receptor tyrosine kinase inhibitor, gefitinib (Iressa), and the nonsteroidal antiandrogen, bicalutamide (Casodex), in prostate cancer cells in vitro.

scientific article published on July 2005

Advances in imaging and in non-surgical salvage treatments after radiorecurrence in prostate cancer: what does the oncologist, radiotherapist and radiologist need to know?

scientific article published on 14 July 2012

Advances in prostate cancer research and treatment.

scientific article published on 18 August 2014

Akt down-modulation induces apoptosis of human prostate cancer cells and synergizes with EGFR tyrosine kinase inhibitors

scientific article

Alexithymia and vaginismus: a preliminary correlation perspective.

scientific article

Angiotensin-converting-enzyme inhibition counteracts angiotensin II-mediated endothelial cell dysfunction by modulating the p38/SirT1 axis.

scientific article published on October 2013

Anti-tumour efficacy on glioma models of PHA-848125, a multi-kinase inhibitor able to cross the blood-brain barrier

scientific article published on May 2013

Antitumor effects of carnertinib in castration resistant prostate cancer models: a comparative study with erlotinib

scientific article published on 28 March 2011

Antitumor effects of saffron-derived carotenoids in prostate cancer cell models

scientific article published on 11 May 2014

Arachidonic acid modulates the crosstalk between prostate carcinoma and bone stromal cells

scientific article

Assessment of dose exposure and image quality in coronary angiography performed by 640-slice CT: a comparison between adaptive iterative and filtered back-projection algorithm by propensity analysis

scientific article published on 20 February 2014

Attachment styles and sexual dysfunctions: a case-control study of female and male sexuality.

scientific article published on 14 August 2014

Azacitidine improves antitumor effects of docetaxel and cisplatin in aggressive prostate cancer models

scientific article published on 19 January 2009

Bicalutamide demonstrates biologic effectiveness in prostate cancer cell lines and tumor primary cultures irrespective of Her2/neu expression levels

scientific article published on 13 March 2009

Bicalutamide increases phospho-Akt levels through Her2 in patients with prostate cancer

scientific article published in September 2007

Bioclinical parameters driving decision-making of subsequent lines of treatment in metastatic castration-resistant prostate cancer

scientific article published on 28 May 2014

Bladder outlet obstruction index and maximal flow rate during urodynamic study as powerful predictors for the detection of urodynamic obstruction in women.

scientific article published in January 2007

Bombesin-dependent pro-MMP-9 activation in prostatic cancer cells requires beta1 integrin engagement

scientific article published on October 2002

CXCR4 pharmacogical inhibition reduces bone and soft tissue metastatic burden by affecting tumor growth and tumorigenic potential in prostate cancer preclinical models.

scientific article published on 12 June 2015

Can Radiotherapy be Combined with Radiofrequency Ablation in the Management of Symptomatic Osteolytic Skeletal Metastasis?

scientific article published on 23 November 2010

Cavoatrial tumor thrombectomy with systemic circulatory arrest and antegrade cerebral perfusion.

scientific article published in April 2007

Challenges to treat hypogonadism in prostate cancer patients: implications for endocrinologists, urologists and radiotherapists

scientific article

Chronic azacitidine treatment results in differentiating effects, sensitizes against bicalutamide in androgen-independent prostate cancer cells

scientific article

Close correlation between MEK/ERK and Aurora-B signaling pathways in sustaining tumorigenic potential and radioresistance of gynecological cancer cell lines.

scientific article published on 5 November 2013

Crocus sativus stigma extract and its major constituent crocin possess significant antiproliferative properties against human prostate cancer.

scientific article published on January 2013

Detection of telomerase activity in prostate massage samples improves differentiating prostate cancer from benign prostatic hyperplasia

scientific article published on 29 January 2004

Differential effects of PXD101 (belinostat) on androgen-dependent and androgen-independent prostate cancer models

scientific article

Dual PI3K/mTOR inhibitor, XL765 (SAR245409), shows superior effects to sole PI3K [XL147 (SAR245408)] or mTOR [rapamycin] inhibition in prostate cancer cell models.

scientific article published on 29 July 2015

Effects of 5 alpha reductase inhibitors on androgen-dependent human prostatic carcinoma cells.

scientific article published on 14 January 2005

Effects of EGFR tyrosine kinase inhibitor erlotinib in prostate cancer cells in vitro.

scientific article

Effects of blocking urokinase receptor signaling by antisense oligonucleotides in a mouse model of experimental prostate cancer bone metastases.

scientific article

Effects of dutasteride on prostate carcinoma primary cultures: a comparative study with finasteride and MK386.

scientific article published on 22 May 2008

Epidermal growth factor modulates prostate cancer cell invasiveness regulating urokinase-type plasminogen activator activity. EGF-receptor inhibition may prevent tumor cell dissemination.

scientific article

Factors associated with climacteric symptoms in women around menopause attending menopause clinics in Italy

scientific article published in November 2005

Foreign bodies aspirated in children: role of bronchoscopy.

scientific article

Gender identity rather than sexual orientation impacts on facial preferences

scientific article published on 27 July 2014

Health-related characteristics and unmet needs of men with erectile dysfunction: a survey in five European countries

scientific article published on 9 December 2013

Her2 crosstalks with TrkA in a subset of prostate cancer cells: rationale for a guided dual treatment

scientific article

Hormonal therapy promotes hormone-resistant phenotype by increasing DNMT activity and expression in prostate cancer models

scientific article published on 11 October 2011

Hypofractionated radical radiotherapy in elderly patients with medically inoperable stage I–II non-small-cell lung cancer

scientific article published on 01 January 2010

Hypoxia sustains glioblastoma radioresistance through ERKs/DNA-PKcs/HIF-1α functional interplay.

scientific article published on 24 March 2014

Image quality and radiation dose of single heartbeat 640-slice coronary CT angiography: a comparison between patients with chronic atrial fibrillation and subjects in normal sinus rhythm by propensity analysis.

scientific article published on 2 January 2015

In vitro and in vivo effects of bicalutamide on the expression of TrkA and P75 neurotrophin receptors in prostate carcinoma

scientific article

Increased levels of DNA methyltransferases are associated with the tumorigenic capacity of prostate cancer cells

scientific article published on 18 December 2012

Integrating psychotherapy and pharmacotherapy in the treatment of premature ejaculation

scientific article

Intravesical instillations with polydeoxyribonucleotides reduce symptoms of radiation-induced cystitis in patients treated with radiotherapy for pelvic cancer: a pilot study.

scientific article published on 10 December 2013

Is testosterone a friend or a foe of the prostate?

scientific article published on April 2011

Late morbidity and oncological outcome after radical hypofractionated radiotherapy in men with prostate cancer

scientific article published on 01 November 2010

MEK/ERK inhibitor U0126 increases the radiosensitivity of rhabdomyosarcoma cells in vitro and in vivo by downregulating growth and DNA repair signals

scientific article published in January 2011

May antioxidant therapy improve sperm parameters of men with persistent oligospermia after retrograde embolization for varicocele?

scientific article published on 3 November 2007

Measurement of the thickness of the urethrovaginal space in women with or without vaginal orgasm

scientific article

Molecular aspects of gefitinib antiproliferative and pro-apoptotic effects in PTEN-positive and PTEN-negative prostate cancer cell lines.

scientific article published on December 2005

Nucleo-cytoplasmic transport as a therapeutic target of cancer

scientific article

Ontogenetic profile of the expression of thyroid hormone receptors in rat and human corpora cavernosa of the penis

scientific article

Oral Platelet Gel Supernatant Plus Supportive Medical Treatment Versus Supportive Medical Treatment in the Management of Radiation-induced Oral Mucositis: A Matched Explorative Active Control Trial by Propensity Analysis

scientific article published on 16 January 2015

Osteoblast-derived TGFbeta-1 modulates matrix degrading protease expression and activity in prostate cancer cells

scientific article published on 01 June 2000

Osteopontin enhances the cell proliferation induced by the epidermal growth factor in human prostate cancer cells

scientific article published on May 2004

Ozarelix, a fourth generation GnRH antagonist, induces apoptosis in hormone refractory androgen receptor negative prostate cancer cells modulating expression and activity of death receptors

scientific article published on September 2010

PXD101 potentiates hormonal therapy and prevents the onset of castration-resistant phenotype modulating androgen receptor, HSP90, and CRM1 in preclinical models of prostate cancer

scientific article published on 21 May 2013

Phenotypic characterization of human prostatic stromal cells in primary cultures derived from human tissue samples

scientific article published on 10 April 2013

Platelet‐Derived Growth Factor Regulation of Type‐5 Phosphodiesterase in Human and Rat Penile Smooth Muscle Cells

Post-traumatic stress disorder, coping strategies and type 2 diabetes: psychometric assessment after L'Aquila earthquake

scientific article published on 19 November 2014

Pregnant Women's Preferences for Men's Faces Differ Significantly from Nonpregnant Women

scientific article published on 5 March 2015

Premature ejaculation results in female sexual distress: standardization and validation of a new diagnostic tool for sexual distress

scientific article

Pyrazolo[3,4-d]pyrimidines c-Src inhibitors reduce epidermal growth factor-induced migration in prostate cancer cells

scientific article published on 14 September 2006

SIAMS survey on sexological screening during the assisted reproductive technologies in Italy.

scientific article

Squamous cell carcinoma of the rectum: The treatment paradigm.

scientific article published on 24 April 2015

Subjective and objective measures of late genitourinary morbidity following hypofractionated radiotherapy in men with prostate cancer.

scientific article published on 23 June 2009

Suppression of EGF-R signaling reduces the incidence of prostate cancer metastasis in nude mice

scientific article published on March 2006

Surgical and biologic outcomes after neoadjuvant bicalutamide treatment in prostate cancer

scientific article published in October 2007

Tamsulosin treatment increases clinical success rate of single extracorporeal shock wave lithotripsy of renal stones

scientific article published in July 2005

The ENDOTRIAL study: a spontaneous, open-label, randomized, multicenter, crossover study on the efficacy of sildenafil, tadalafil, and vardenafil in the treatment of erectile dysfunction.

scientific article published on 29 June 2009

The TORC1/TORC2 inhibitor, Palomid 529, reduces tumor growth and sensitizes to docetaxel and cisplatin in aggressive and hormone-refractory prostate cancer cells.

scientific article published on July 2011

The ontogenetic expression pattern of type 5 phosphodiesterase correlates with androgen receptor expression in rat corpora cavernosa

scientific article published on 9 December 2008

The psychosexual profile of sexual assistants: an internet-based explorative study

scientific article

The sexual attraction toward disabilities: a preliminary internet-based study.

scientific article

Topical application of platelet supernatant gel in the management of radiotherapy-induced mucositis: a case report

scientific article published on 22 October 2013

Torc1/Torc2 inhibitor, Palomid 529, enhances radiation response modulating CRM1-mediated survivin function and delaying DNA repair in prostate cancer models

scientific article published on 8 April 2014

Treatment of Solitary Painful Osseous Metastases with Radiotherapy, Cryoablation or Combined Therapy: Propensity Matching Analysis in 175 Patients

scientific article published on 23 June 2015

Urodynamic Obstruction in Women With Stress Urinary Incontinence—Do Nonintubated Uroflowmetry and Symptoms Aid Diagnosis?

scientific article published on 16 July 2007

Urodynamic parameters after solifenacin treatment in men with overactive bladder symptoms and detrusor underactivity.

scientific article published in January 2009

Valproic acid induces apoptosis in prostate carcinoma cell lines by activation of multiple death pathways

scientific article published on November 2006

Vesicle-associated urokinase plasminogen activator promotes invasion in prostate cancer cell lines

scientific article published on January 2000

Vitamin D protects human endothelial cells from H₂O₂ oxidant injury through the Mek/Erk-Sirt1 axis activation.

scientific article

XPO1/CRM1-selective inhibitors of nuclear export (SINE) reduce tumor spreading and improve overall survival in preclinical models of prostate cancer (PCa).

scientific article published on 5 October 2014

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