Search filters

List of works by Kirk J McManus

A Gly565-->Ala substitution in human erythroid band 3 accounts for the Wu blood group polymorphism

scientific article

A novel multiplexed, image-based approach to detect phenotypes that underlie chromosome instability in human cells

scientific article

ATM-dependent DNA damage-independent mitotic phosphorylation of H2AX in normally growing mammalian cells.

scientific article

Amino acid substitutions in human erythroid protein band 3 account for the low-incidence antigens NFLD and BOW

scientific article published on 01 March 2000

An Automated, Single Cell Quantitative Imaging Microscopy Approach to Assess Micronucleus Formation, Genotoxicity and Chromosome Instability

scientific article published on 02 February 2020

An Evolutionarily Conserved Synthetic Lethal Interaction Network Identifies FEN1 as a Broad-Spectrum Target for Anticancer Therapeutic Development ⬇️

scientific article published on January 31, 2013

An amino acid substitution in the putative second extracellular loop of RBC band 3 accounts for the Froese blood group polymorphism

scientific article published in October 2000

Catalytic function of the PR-Set7 histone H4 lysine 20 monomethyltransferase is essential for mitotic entry and genomic stability

scientific article published on 14 May 2008

Characterizing Microsatellite Instability and Chromosome Instability in Interval Colorectal Cancers

Characterizing the prevalence of chromosome instability in interval colorectal cancer

scientific article

Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers

scientific article

Chromosome Instability; Implications in Cancer Development, Progression, and Clinical Outcomes

scientific article published on 29 March 2020

Chromosome location of genes encoding human blood groups

scientific article

Correction: An Evolutionarily Conserved Synthetic Lethal Interaction Network Identifies FEN1 as a Broad-Spectrum Target for Anticancer Therapeutic Development

scientific article published on 18 February 2013

Detecting Chromosome Instability in Cancer: Approaches to Resolve Cell-to-Cell Heterogeneity

scientific article published on 15 February 2019

Developing Targeted Therapies That Exploit Aberrant Histone Ubiquitination in Cancer

scientific article published on 16 February 2019

Diminished Condensin Gene Expression Drives Chromosome Instability That May Contribute to Colorectal Cancer Pathogenesis

scientific article published on 28 July 2019

Distinct dynamics and distribution of histone methyl-lysine derivatives in mouse development

scientific article published in December 2004

Distinctive Swann blood group genotypes: molecular investigations

scientific article published on 01 January 2000

Dynamic changes in histone H3 lysine 9 methylations: identification of a mitosis-specific function for dynamic methylation in chromosome congression and segregation

scientific article published on 21 December 2005

Establishing a biological profile for interval colorectal cancers.

scientific article published on 20 May 2014

Evolving Therapeutic Strategies to Exploit Chromosome Instability in Cancer

scientific article published in November 2017

KIF11 silencing and inhibition induces chromosome instability that may contribute to cancer

scientific article published on 16 May 2017

Mitotic accumulation of dimethylated lysine 79 of histone H3 is important for maintaining genome integrity during mitosis in human cells

scientific article published on 22 December 2014

Predisposition to Cancer Caused by Genetic and Functional Defects of Mammalian Atad5 ⬇️

scientific article published on August 25, 2011

Quantitative analysis of CBP- and P300-induced histone acetylations in vivo using native chromatin.

scientific article published in November 2003

Reduced Expression of Genes Regulating Cohesion Induces Chromosome Instability that May Promote Cancer and Impact Patient Outcomes

scientific article published on 17 January 2020

Reduced RBX1 expression induces chromosome instability and promotes cellular transformation in high-grade serous ovarian cancer precursor cells

scientific article published on 05 December 2020

Reduced SKP1 Expression Induces Chromosome Instability through Aberrant Cyclin E1 Protein Turnover

scientific article published on 25 February 2020

Reduced SKP1 and CUL1 expression underlies increases in Cyclin E1 and chromosome instability in cellular precursors of high-grade serous ovarian cancer

Regulation of chromatin structure via histone post-translational modification and the link to carcinogenesis.

scientific article published on December 2013

Sequencing of Candidate Chromosome Instability Genes in Endometrial Cancers Reveals Somatic Mutations in ESCO1, CHTF18, and MRE11A ⬇️

scientific article published on June 3, 2013

Sister chromatid cohesion defects are associated with chromosome instability in Hodgkin lymphoma cells ⬇️

scientific article published on August 20, 2013

Specific synthetic lethal killing of RAD54B-deficient human colorectal cancer cells by FEN1 silencing.

scholarly article

Synthetic genetic targeting of genome instability in cancer.

scientific article published on 24 June 2013

Synthetic lethal targeting of RNF20 through PARP1 silencing and inhibition

scientific article published in May 2017

Synthetic lethal targeting of superoxide dismutase 1 selectively kills RAD54B-deficient colorectal cancer cells

scientific article published on 03 September 2013

Targeting SOD1 induces synthetic lethal killing in BLM- and CHEK2-deficient colorectal cancer cells

scientific article

The ELO blood group polymorphism is located in the putative first extracellular loop of human erythrocyte band 3.

scientific article

The F-box protein, FBXO7, is required to maintain chromosome stability in humans

scientific article published on 01 May 2022

The enigmatic oncogene and tumor suppressor-like properties of RAD54B: Insights into genome instability and cancer

scientific article published on 13 March 2017

The relationship between histone H3 phosphorylation and acetylation throughout the mammalian cell cycle.

scientific article published on August 2006

The steroid receptor RNA activator protein (SRAP) controls cancer cell migration/motility.

scientific article

The synthetic lethal killing of RAD54B-deficient colorectal cancer cells by PARP1 inhibition is enhanced with SOD1 inhibition.

scientific article

The temporal dynamics of chromosome instability in ovarian cancer cell lines and primary patient samples.

scientific article

The transcriptional regulator CBP has defined spatial associations within interphase nuclei.

scientific article

Ubiquitin Specific Peptidase 22 Regulates Histone H2B Mono-Ubiquitination and Exhibits Both Oncogenic and Tumor Suppressor Roles in Cancer

scientific article published on 6 December 2017

Using quantitative imaging microscopy to define the target substrate specificities of histone post-translational-modifying enzymes.

scientific article published in August 2005

Paulina is supported by:

About Paulina

Help