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List of works by Adam K Wheatley

A Simple Flow-Cytometric Method Measuring B Cell Surface Immunoglobulin Avidity Enables Characterization of Affinity Maturation to Influenza A Virus.

scientific article published on 4 August 2015

A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.

scientific article published on 19 March 2018

Abnormal B cell memory subsets dominate HIV-specific responses in infected individuals

scientific article

Adaptive immunity to human coronaviruses is widespread but low in magnitude

scientific article

Adenovirus vector produced Zika virus-like particles induce a long-lived neutralising antibody response in mice

scientific article published in 2023

Aggregation by peptide conjugation rescues poor immunogenicity of the HA stem

scientific article published on 02 November 2020

Anti-Influenza Hyperimmune Immunoglobulin Enhances Fc-Functional Antibody Immunity During Human Influenza Infection

scientific article published on 01 September 2018

Antibody Responses with Fc-Mediated Functions after Vaccination of HIV-Infected Subjects with Trivalent Influenza Vaccine

scientific article

Antibody-dependent cellular cytotoxicity and influenza virus

scientific article

Antibody-dependent enhancement and SARS-CoV-2 vaccines and therapies

scientific article published on 09 September 2020

Antibody-dependent phagocytosis (ADP) responses following trivalent inactivated influenza vaccination of younger and older adults.

scientific article

At Least Three Doses of Leading Vaccines Essential for Neutralisation of SARS-CoV-2 Omicron Variant

scientific article published on 17 May 2022

Author Correction: A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite

scientific article published on 01 January 2019

Author Correction: Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses

scientific article published on 01 June 2019

Butyrophilin 2A1 is essential for phosphoantigen reactivity by γδ T cells

scientific article published on 09 January 2020

CD8<sup>+</sup> T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope display high naive precursor frequency and TCR promiscuity

scientific article published on 15 April 2021

Cellular Interactions of Liposomes and PISA Nanoparticles during Human Blood Flow in a Microvascular Network

scientific article published on 25 June 2020

Circulating TFH cells, serological memory, and tissue compartmentalization shape human influenza-specific B cell immunity.

scientific article published in February 2018

Co-expression of miRNA targeting the expression of PERK, but not PKR, enhances cellular immunity from an HIV-1 Env DNA vaccine

scientific article

Cross-lineage protection by human antibodies binding the influenza B hemagglutinin

scientific article published in Nature Communications

Defining B cell immunodominance to viruses

scientific article published on 13 February 2017

Design of Nanoparticulate Group 2 Influenza Virus Hemagglutinin Stem Antigens That Activate Unmutated Ancestor B Cell Receptors of Broadly Neutralizing Antibody Lineages

scientific article published on 26 February 2019

Distinct systems serology features in children, elderly and COVID patients

scientific article published on 18 May 2020

Efficient transcription through an intron requires the binding of an Sm-type U1 snRNP with intact stem loop II to the splice donor

scientific article published on 13 January 2010

Fc functional antibody responses to adjuvanted versus unadjuvanted seasonal influenza vaccination in community-dwelling older adults

scientific article published on 05 February 2020

Fc or not Fc; that is the question: Antibody Fc-receptor interactions are key to universal influenza vaccine design

scientific article

Fc-dependent functions are redundant to efficacy of anti-HIV antibody PGT121 in macaques

article

Flow cytometry reveals that H5N1 vaccination elicits cross-reactive stem-directed antibodies from multiple Ig heavy-chain lineages.

scientific article published on 05 February 2014

H5N1 Vaccine-Elicited Memory B Cells Are Genetically Constrained by the IGHV Locus in the Recognition of a Neutralizing Epitope in the Hemagglutinin Stem.

scientific article published on 15 June 2015

HIV-dependent depletion of influenza-specific memory B cells impacts B cell responsiveness to seasonal influenza immunisation.

scientific article published on 25 May 2016

Hemagglutinin head-specific responses dominate over stem-specific responses following prime boost with mismatched vaccines

scientific article published on 14 November 2019

High CD26 and Low CD94 Expression Identifies an IL-23 Responsive Vδ2+ T Cell Subset with a MAIT Cell-like Transcriptional Profile

scientific article published on 01 June 2020

Humoral and circulating follicular helper T cell responses in recovered patients with COVID-19

scientific article published on 13 July 2020

Hyperimmune bovine colostrum as a low-cost, large-scale source of antibodies with broad neutralizing activity for HIV-1 envelope with potential use in microbicides.

scientific article

Identification of murine antigen-specific T follicular helper cells using an activation-induced marker assay

scientific article published on 22 February 2019

Immune profiling of influenza-specific B cell and T cell responses in macaques using flow cytometry-based assays

scientific article published on 01 August 2020

Immunogenic profile of SARS-CoV-2 spike in individuals recovered from COVID-19

scientific article published on 21 May 2020

Immunological Principles Guiding the Rational Design of Particles for Vaccine Delivery

scientific article published on 11 January 2017

Immunological basis for enhanced immunity of nanoparticle vaccines

scientific article published on 14 February 2019

Immunomodulation Induced by Host Pathogen Interaction

scientific article published on 29 August 2019

Improving immunological insights into the ferret model of human viral infectious disease

scientific article published on 03 October 2019

Inducible Bronchus-Associated Lymphoid Tissues (iBALT) Serve as Sites of B Cell Selection and Maturation Following Influenza Infection in Mice

scientific article published on 29 March 2019

Induction of HIV-1 subtype B and AE-specific neutralizing antibodies in mice and macaques with DNA prime and recombinant gp140 protein boost regimens.

scientific article published on 25 August 2009

Induction of humoral and cellular immune responses against the HIV-1 envelope protein using γ-retroviral virus-like particles

scientific article

Influenza lineage extinction during the COVID-19 pandemic?

scientific article published in 2021

Integrated immune dynamics define correlates of COVID-19 severity and antibody responses

scientific article published on 05 February 2021

Intranasal live influenza vaccine priming elicits localized B cell responses in mediastinal lymph nodes

scientific article published on 14 February 2018

Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain

scientific article published on 25 September 2021

Link between Low-Fouling and Stealth: A Whole Blood Biomolecular Corona and Cellular Association Analysis on Nanoengineered Particles

scientific article published on 18 April 2019

Live Adenovirus Type 4 Recombinants Induce Durable Neutralizing Antibody Responses to Influenza H5 with High Levels of Somatic Hypermutation in Humans.

scientific article

Longitudinal dynamics of the HIV-specific B cell response during intermittent treatment of primary HIV infection

scientific article

Loss of circulating CD4 T cells with B cell helper function during chronic HIV infection

scientific article published on 30 January 2014

Low pH Exposure During Immunoglobulin G Purification Methods Results in Aggregates That Avidly Bind Fcγ Receptors: Implications for Measuring Fc Dependent Antibody Functions

scientific article published on 11 October 2019

Lung-resident memory B cells established after pulmonary influenza infection display distinct transcriptional and phenotypic profiles

scientific article

Measuring immunity to SARS-CoV-2 infection: comparing assays and animal models

scientific article published on 02 November 2020

Modulating Targeting of Poly(ethylene glycol) Particles to Tumor Cells Using Bispecific Antibodies

scientific article published on 14 March 2019

Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses

scientific article published on 11 February 2019

Need for Speed: From Human SARS-CoV-2 Samples to Protective and Efficacious Antibodies in Weeks

scientific article published on 01 July 2020

Neutralising antibody titres as predictors of protection against SARS-CoV-2 variants and the impact of boosting: a meta-analysis ⬇️

journal article from 'The Lancet Microbe' published in 2021

Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection

scientific article

New Technologies for Influenza Vaccines

scientific article published on 06 November 2020

OA021-03. Design and development of DNA vaccines for the co-expression of micro-RNA and HIV-1 Env

article

Person-Specific Biomolecular Coronas Modulate Nanoparticle Interactions with Immune Cells in Human Blood

scientific article published on 28 October 2020

Preferential induction of cross-group influenza A hemagglutinin stem-specific memory B cells after H7N9 immunization in humans

scientific article published on July 2017

Prolonged evolution of the memory B cell response induced by a replicating adenovirus-influenza H5 vaccine

scientific article published on 01 April 2019

Prospects for antibody-based universal influenza vaccines in the context of widespread pre-existing immunity.

scientific article

Reconstituted B cell receptor signaling reveals carbohydrate-dependent mode of activation

scientific article published on 31 October 2016

Safety, tolerability, and immunogenicity of influenza vaccination with a high-density microarray patch: Results from a randomized, controlled phase I clinical trial

scientific article published on 17 March 2020

Self-assembling influenza nanoparticle vaccines drive extended germinal center activity and memory B cell maturation

scientific article published on 21 May 2020

Sequencing B cell receptors from ferrets (Mustela putorius furo)

scientific article published on 29 May 2020

Structural basis of biased T cell receptor recognition of an immunodominant HLA-A2 epitope of the SARS-CoV-2 spike protein

scientific article published on 10 August 2021

Subdominance and poor intrinsic immunogenicity limit humoral immunity targeting influenza HA stem

scientific article published on 22 January 2019

Suboptimal SARS-CoV-2-specific CD8+ T cell response associated with the prominent HLA-A*02:01 phenotype

scientific article published on 10 September 2020

The aryl hydrocarbon receptor controls cell-fate decisions in B cells.

scientific article published on 23 December 2016

Twist in the Tail: Escape from HIV Neutralising Antibodies at a Single Site Confers Broad Susceptibility to Others

scientific article published on 20 September 2016

Utility of the Sindbis replicon system as an Env-targeted HIV vaccine.

scientific article published on 13 March 2013

Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses

scientific article

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