List of works - Salvatore Ferla

3-Aryl/Heteroaryl-5-amino-1-(3′,4′,5′-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of tubulin polymerization

scholarly article by Romeo Romagnoli published in October 2018

A new antiviral scaffold for human norovirus identified with computer-aided approaches on the viral polymerase

scientific article published on 05 December 2019

A new series of bicalutamide, enzalutamide and enobosarm derivatives carrying pentafluorosulfanyl (SF5) and pentafluoroethyl (C2F5) substituents: Improved antiproliferative agents against prostate cancer

scientific article published on 03 July 2019

Broad-spectrum non-nucleoside inhibitors for caliciviruses.

scientific article

Combining bioinformatics, cheminformatics, functional genomics and whole organism approaches for identifying epigenetic drug targets in Schistosoma mansoni

scientific article published on 13 November 2018

Computational Studies towards the Identification of Novel Rhodopsin-Binding Compounds as Chemical Chaperones for Misfolded Opsins

scientific article published on 23 October 2020

Design and Synthesis of Potent in Vitro and in Vivo Anticancer Agents Based on 1-(3',4',5'-Trimethoxyphenyl)-2-Aryl-1H-Imidazole

scientific article published on 24 May 2016

Design and synthesis of novel bicalutamide and enzalutamide derivatives as antiproliferative agents for the treatment of prostate cancer

scientific article published on 22 April 2016

Design, synthesis and biological evaluation of novel vicinal diaryl-substituted 1H-Pyrazole analogues of combretastatin A-4 as highly potent tubulin polymerization inhibitors

scientific article published on 01 August 2019

Discovery of novel multi-target indole-based derivatives as potent and selective inhibitors of chikungunya virus replication

scientific article published on 31 October 2016

In silico screening for human norovirus antivirals reveals a novel non-nucleoside inhibitor of the viral polymerase.

scientific article published on 7 March 2018

Networks of enzymatically oxidized membrane lipids support calcium-dependent coagulation factor binding to maintain hemostasis.

scientific article

Novel styryl-indoles as small molecule inhibitors of 25-hydroxyvitamin D-24-hydroxylase (CYP24A1): Synthesis and biological evaluation

scientific article

Novel symmetrical phenylenediamines as potential anti-hepatitis C virus agents.

scientific article published on 4 November 2016

Polyfluorinated groups in medicinal chemistry.

scientific article published on January 2015

Quercetin derivatives as novel antihypertensive agents: Synthesis and physiological characterization

scientific article published on 26 November 2015

Rational design and synthesis of novel anti-prostate cancer agents bearing a 3,5-bis-trifluoromethylphenyl moiety

scientific article published on 2 June 2016

Rational design and synthesis of novel phenylsulfonyl-benzamides as anti-prostate cancer agents.

scientific article published on 26 May 2017

Small-molecule inhibitors of 25-hydroxyvitamin D-24-hydroxylase (CYP24A1): synthesis and biological evaluation

scientific article published on 8 September 2014

Structure-activity relationship study of itraconazole, a broad-range inhibitor of picornavirus replication that targets oxysterol-binding protein (OSBP)

scientific article published on 26 May 2018

Synthesis and biological evaluation of 6-substituted-5-fluorouridine ProTides

scientific article published on 2 December 2017

List of works by Salvatore Ferla

3-Aryl/Heteroaryl-5-amino-1-(3′,4′,5′-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of tubulin polymerization

A new antiviral scaffold for human norovirus identified with computer-aided approaches on the viral polymerase

A new series of bicalutamide, enzalutamide and enobosarm derivatives carrying pentafluorosulfanyl (SF5) and pentafluoroethyl (C2F5) substituents: Improved antiproliferative agents against prostate cancer

Broad-spectrum non-nucleoside inhibitors for caliciviruses.

Combining bioinformatics, cheminformatics, functional genomics and whole organism approaches for identifying epigenetic drug targets in Schistosoma mansoni

Computational Studies towards the Identification of Novel Rhodopsin-Binding Compounds as Chemical Chaperones for Misfolded Opsins

Design and Synthesis of Potent in Vitro and in Vivo Anticancer Agents Based on 1-(3',4',5'-Trimethoxyphenyl)-2-Aryl-1H-Imidazole

Design and synthesis of novel bicalutamide and enzalutamide derivatives as antiproliferative agents for the treatment of prostate cancer

Design, synthesis and biological evaluation of novel vicinal diaryl-substituted 1H-Pyrazole analogues of combretastatin A-4 as highly potent tubulin polymerization inhibitors

Discovery of novel multi-target indole-based derivatives as potent and selective inhibitors of chikungunya virus replication

In silico screening for human norovirus antivirals reveals a novel non-nucleoside inhibitor of the viral polymerase.

Networks of enzymatically oxidized membrane lipids support calcium-dependent coagulation factor binding to maintain hemostasis.

Novel styryl-indoles as small molecule inhibitors of 25-hydroxyvitamin D-24-hydroxylase (CYP24A1): Synthesis and biological evaluation

Novel symmetrical phenylenediamines as potential anti-hepatitis C virus agents.

Polyfluorinated groups in medicinal chemistry.

Quercetin derivatives as novel antihypertensive agents: Synthesis and physiological characterization

Rational design and synthesis of novel anti-prostate cancer agents bearing a 3,5-bis-trifluoromethylphenyl moiety

Rational design and synthesis of novel phenylsulfonyl-benzamides as anti-prostate cancer agents.

Small-molecule inhibitors of 25-hydroxyvitamin D-24-hydroxylase (CYP24A1): synthesis and biological evaluation

Structure-activity relationship study of itraconazole, a broad-range inhibitor of picornavirus replication that targets oxysterol-binding protein (OSBP)

Synthesis and biological evaluation of 6-substituted-5-fluorouridine ProTides