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List of works by Ching-Hsuan Tung

A Bioluminogenic Probe for Monitoring Tyrosinase Activity

scientific article published on 3 January 2017

A Branched Fluorescent Peptide Probe for Imaging of Activated Platelets

scientific article published on 01 January 2005

A Multiresponsive Nanohybrid to Enhance the Lysosomal Delivery of Oxygen and Photosensitizers

scientific article published on 09 September 2019

A Quick Responsive Fluorogenic pH Probe for Ovarian Tumor Imaging

scientific article

A benzothiazole alkyne fluorescent sensor for Cu detection in living cell

scientific article published on 11 January 2012

A cancer cell-activatable aptamer-reporter system for one-step assay of circulating tumor cells

scientific article published on 12 August 2014

A cardiac tissue-specific binding agent of troponin I.

scientific article published on October 2012

A cell surface clicked navigation system to direct specific bone targeting

scientific article published on 26 December 2017

A fabricated siRNA nanoparticle for ultra-long gene silencing in vivo.

scientific article

A fluorescent nanosensor for apoptotic cells

scientific article published in March 2006

A fluorogenic probe for β-galactosidase activity imaging in living cells.

scientific article published on 19 September 2013

A mitochondrial targeted fusion peptide exhibits remarkable cytotoxicity

scientific article published in August 2006

A novel method for imaging apoptosis using a caspase-1 near-infrared fluorescent probe

scientific article published on March 2004

A practical approach for the preparation of monofunctional azulenyl squaraine dye.

scientific article

A self-immolative reporter for beta-galactosidase sensing

scientific article published on 01 March 2007

Adenovirus-mediated expression of antisense urokinase plasminogen activator receptor and antisense cathepsin B inhibits tumor growth, invasion, and angiogenesis in gliomas

scientific article published in June 2004

An authentic imaging probe to track cell fate from beginning to end.

scientific article published on 17 October 2014

An effective method of on-resin disulfide bond formation in peptides

scientific article published on 01 March 2005

Aptamer-Gemcitabine Conjugates with Enzymatically Cleavable Linker for Targeted Delivery and Intracellular Drug Release in Cancer Cells

scientific article published on 30 April 2022

Arginine containing peptides as delivery vectors.

scientific article

Beyond chemotherapeutics: cisplatin as a temporary buckle to fabricate drug-loaded nanogels

scientific article published on 21 December 2016

Bidentate iminodiacetate modified dendrimer for bone imaging.

scientific article published on 20 January 2017

Cisplatin Cross-Linked Multifunctional Nanodrugplexes for Combination Therapy

scientific article

Conjugation of a photosensitizer to an oligoarginine-based cell-penetrating peptide increases the efficacy of photodynamic therapy

scientific article published on April 2006

Construction of a novel chimera consisting of a chelator-containing Tat peptide conjugated to a morpholino antisense oligomer for technetium-99m labeling and accelerating cellular kinetics.

scientific article

DNA binding chelates for nonviral gene delivery imaging

scientific article published in April 2001

Design and synthesis of a mitochondria-targeting carrier for small molecule drugs.

scientific article

Design, synthesis and assay of tetrapeptide-acridine mimics of ribonuclease

scientific article published on 01 October 1992

Design, synthesis, and characterization of urokinase plasminogen-activator-sensitive near-infrared reporter

scientific article

Detection of dysplastic intestinal adenomas using enzyme-sensing molecular beacons in mice

scientific article published on 01 February 2002

Detection of hydroxyapatite in calcified cardiovascular tissues

scientific article

Detection of pancreatic cancer tumours and precursor lesions by cathepsin E activity in mouse models.

scientific article

Developing Visible Fluorogenic ‘Click-On’ Dyes for Cellular Imaging

scientific article published on August 15, 2011

Developing a far-red fluorogenic beta-galactosidase probe for senescent cell imaging and photoablation

scientific article published on 04 February 2022

Developing a peptide-based near-infrared molecular probe for protease sensing

scientific article

Development of a dual fluorogenic and chromogenic dipeptidyl peptidase IV substrate

scientific article published on 6 March 2006

Development of a fluorescent cardiomyocyte specific binding probe

scientific article

Development of benzothiazole 'click-on' fluorogenic dyes

scientific article published on 5 November 2010

Distribution of calcification in carotid endarterectomy tissues: comparison of micro-computed tomography imaging with histology.

scientific article published on 5 September 2014

Dual-Specificity Interaction of HIV-1 TAR RNA with Tat Peptide-Oligonucleotide Conjugates

scientific article published on May 1, 1995

Early diagnosis of osteoarthritis using cathepsin B sensitive near-infrared fluorescent probes

scientific article (publication date: March 2004)

Effect of lyso-phosphatidylcholine and Schnurri-3 on osteogenic transdifferentiation of vascular smooth muscle cells to calcifying vascular cells in 3D culture

scientific article published on 14 March 2013

Effective gene silencing by multilayered siRNA-coated gold nanoparticles

scientific article published on 30 December 2010

Enhanced cellular uptake and metabolic stability of lipo-oligoarginine peptides.

scientific article

Enhanced tumor detection using a folate receptor-targeted near-infrared fluorochrome conjugate.

scientific article published on May 2003

Enhancing membrane permeability by fatty acylation of oligoarginine peptides

scientific article

Enhancing the Cellular Delivery of Nanoparticles using Lipo-Oligoarginine Peptides

scientific article

Enzyme-targeted fluorescent imaging probes on a multiple antigenic peptide core

scientific article published on 01 July 2006

Exploring the structural requirements of collagen-binding peptides

scientific article published on April 2013

Facile metabolic glycan labeling strategy for exosome tracking.

scientific article published on 2 February 2018

Factor XIII deficiency causes cardiac rupture, impairs wound healing, and aggravates cardiac remodeling in mice with myocardial infarction

scientific article

Feasibility of in vivo multichannel optical imaging of gene expression: experimental study in mice

scientific article published on 01 August 2002

Fluorescence molecular tomography resolves protease activity in vivo

scientific article published on 24 June 2002

Fluorescence probe with a pH-sensitive trigger

scientific article published in March 2006

Fluorescent peptide probes for in vivo diagnostic imaging

scientific article published on 01 January 2004

Fortschritte in der optischen Bildgebung

scientific article published on 15 February 2001

Gold nanorod-photosensitizer complex for near-infrared fluorescence imaging and photodynamic/photothermal therapy in vivo

scientific article published on 18 January 2011

High efficiency synthesis of a bioconjugatable near-infrared fluorochrome

scientific article published on September 2003

High-efficiency intracellular magnetic labeling with novel superparamagnetic-Tat peptide conjugates

scientific article published in March 1999

Hybridization properties of oligodeoxynucleotide pairs bridged by polyarginine peptides

scientific article published on February 1996

Imaging gene delivery in a mouse model of congenital neuronal ceroid lipofuscinosis

scientific article published on September 8, 2011

Imaging of differential protease expression in breast cancers for detection of aggressive tumor phenotypes

scientific article published on 01 March 2002

Imaging reactive oxygen species in arthritis

scientific article published in July 2004

In vivo imaging of HIV protease activity in amplicon vector-transduced gliomas

scientific article

In vivo imaging of S-TRAIL-mediated tumor regression and apoptosis.

scientific article published in June 2005

In vivo imaging of beta-galactosidase activity using far red fluorescent switch

scientific article published in March 2004

In vivo imaging of protease activity in arthritis: a novel approach for monitoring treatment response

scientific article published on 01 August 2004

In vivo imaging of proteolytic activity in atherosclerosis

article

In vivo imaging of thrombin activity in experimental thrombi with thrombin-sensitive near-infrared molecular probe

scientific article published in November 2002

In-vivo imaging of tumor associated urokinase-type plasminogen activator activity

scientific article published on May 2006

Inducible release of TRAIL fusion proteins from a proapoptotic form for tumor therapy

scientific article published in May 2004

Inflammation in atherosclerosis: visualizing matrix metalloproteinase action in macrophages in vivo

scientific article published on 26 June 2006

Intermolecular [8+2] cycloaddition reactions of 2H-3-methoxycarbonylcyclohepta[b]furan-2-one with vinyl ethers: an approach to bicyclo[5.3.0]azulene derivatives

scientific article

Layer-by-layer construction of an oxygen-generating photo-responsive nanomedicine for enhanced photothermal and photodynamic combination therapy

scientific article published on 03 May 2019

Layered nanoprobe for long-lasting fluorescent cell label

scientific article published on 7 August 2012

Lipo-oligoarginine-based intracellular delivery

scientific article published on 01 January 2013

Lipo-oligoarginines as effective delivery vectors to promote cellular uptake

scientific article published on 9 August 2010

Live imaging of cysteine-cathepsin activity reveals dynamics of focal inflammation, angiogenesis, and polyp growth

scientific article (publication date: 2008)

Lysosome Enlargement Enhanced Photochemotherapy Using a Multifunctional Nanogel

scientific article

Macrocyclic chelators with paramagnetic cations are internalized into mammalian cells via a HIV-tat derived membrane translocation peptide

scientific article

Mechanism-based fluorescent reporter for protein kinase A detection

scientific article published in August 2005

Membrane permeable esterase-activated fluorescent imaging probe

scientific article published on 20 July 2007

Molecular imaging of Cathepsin E-positive tumors in mice using a novel protease-activatable fluorescent probe.

scientific article

Molecular imaging of MMP expression and therapeutic MMP inhibition

scientific article published on August 2002

Molecular imaging of factor XIIIa activity in thrombosis using a novel, near-infrared fluorescent contrast agent that covalently links to thrombi

scientific article

Monofunctional near-infrared fluorochromes for imaging applications

scientific article published on September 2005

Multilayered Activatable Nanoprobe for Ultra-Bright Tumor Imaging

scientific article published on 19 November 2019

Nanoparticle Delivery of miR-708 Mimetic Impairs Breast Cancer Metastasis

scientific article published on 24 January 2019

Near-infrared fluorescent imaging of cerebral thrombi and blood-brain barrier disruption in a mouse model of cerebral venous sinus thrombosis

scientific article

Near-infrared fluorescent imaging of matrix metalloproteinase activity after myocardial infarction

scientific article published on 4 April 2005

Near-infrared optical imaging of protease activity for tumor detection

scientific article published on 01 December 1999

Non-invasive optical detection of cathepsin K-mediated fluorescence reveals osteoclast activity in vitro and in vivo.

scientific article published on 22 October 2008

Novel Factor XIII Probes for Blood Coagulation Imaging

article

Novel branching membrane translocational peptide as gene delivery vector

scientific article published on November 2002

Novel near-infrared cyanine fluorochromes: synthesis, properties, and bioconjugation

scientific article

Oligonucleotide aptamer-drug conjugates for targeted therapy of acute myeloid leukemia.

scientific article published on 15 July 2015

Oligonucleotide-poly-L-ornithine conjugates: binding to complementary DNA and RNA.

scholarly article

Optical Imaging of Matrix Metalloproteinase–2 Activity in Tumors: Feasibility Study in a Mouse Model

scientific article published on November 1, 2001

Optical Visualization of Cathepsin K Activity in Atherosclerosis With a Novel, Protease-Activatable Fluorescence Sensor

scientific article published on 09 April 2007

Optical zymography for specific detection of urokinase plasminogen activator activity in biological samples

scientific article published in March 2005

Osteocalcin biomimic recognizes bone hydroxyapatite

scientific article published on 9 June 2011

Pancreatic cancer-associated Cathepsin E as a drug activator

scientific article published on February 26, 2013

Peptide-based biomaterials for protease-enhanced drug delivery

scientific article published on 01 April 2006

Polyamine-linked oligonucleotides for DNA triple helix formation

scientific article published on November 1993

Preparation and physical properties of conjugates of oligodeoxynucleotides with poly(delta)ornithine peptides

scientific article published on 01 January 1993

Preparation of a cathepsin D sensitive near-infrared fluorescence probe for imaging

scientific article published on September 1999

Preparation of oligonucleotide-peptide conjugates

scientific article published on 01 November 1991

Protease-mediated phototoxicity of a polylysine-chlorin(E6) conjugate

scientific article published on July 2006

Protease-sensitive fluorescent nanofibers

scientific article published on 5 October 2007

Proteolysis: a biological process adapted in drug delivery, therapy, and imaging.

scientific article published on September 2009

Real-Time Visualization of Lysosome Destruction Using a Photosensitive Toluidine Blue Nanogel.

scientific article published on 4 January 2018

Redox-responsive cisplatin nanogels for anticancer drug delivery

scholarly article by Weiqi Zhang & Ching-Hsuan Tung published 24 July 2018 in Chemical Communications

Selective antitumor effect of novel protease-mediated photodynamic agent

scientific article published on 01 July 2006

Selective fluorescence probes for dipeptidyl peptidase activity-fibroblast activation protein and dipeptidyl peptidase IV.

scientific article published on 10 May 2007

Selective photo-ablation of glioma cells using an enzyme activatable photosensitizer

scientific article published on 22 October 2020

Sensing phosphatase activity by using gold nanoparticles

scientific article published on 01 January 2007

Sensitive luciferin derived probes for selective carboxypeptidase activity

scientific article published on 14 May 2011

Sequence-Independent DNA Nanogel as a Potential Drug Carrier.

scientific article published on 12 September 2017

Size optimization of synthetic graft copolymers for in vivo angiogenesis imaging

scientific article published in March 2001

Smart dual-functional warhead for folate receptor-specific activatable imaging and photodynamic therapy.

scientific article

Specific and sensitive tumor imaging using biostable oligonucleotide aptamer probes

scientific article published on 19 July 2014

Stabilization of DNA triple-helix formation by appended cationic peptides

scientific article published on 01 September 1996

Structural modification of protease inducible preprogrammed nanofiber precursor

scientific article published on 05 January 2008

Sugar sensing based on induced pH changes

scientific article published on 09 March 2007

Survival of Tropheryma whipplei, the agent of Whipple's disease, requires phagosome acidification

scientific article published on March 2002

Synthesis and properties of sulfhydryl-reactive near-infrared cyanine fluorochromes for fluorescence imaging.

scientific article

Synthesis of oligoarginine-oligonucleotide conjugates and oligoarginine-bridged oligonucleotide pairs

scientific article published on 01 September 1994

Synthetic glycopeptide-based delivery systems for systemic gene targeting to hepatocytes

scientific article published on 01 April 2000

Synthetic peptide-based DNA complexes for nonviral gene delivery

scientific article published on 01 March 1998

Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells.

scientific article

The Crohn's disease-associated adherent-invasive Escherichia coli strain LF82 replicates in mature phagolysosomes within J774 macrophages.

scientific article published on March 2006

Tissue inhibitor of metalloproteinase-3 expression from an oncolytic adenovirus inhibits matrix metalloproteinase activity in vivo without affecting antitumor efficacy in malignant glioma.

scientific article published on October 2005

Total control of fat cells from adipogenesis to apoptosis using a xanthene analog

scientific article

Transglutaminase activity in acute infarcts predicts healing outcome and left ventricular remodelling: implications for FXIII therapy and antithrombin use in myocardial infarction.

scientific article

Tumor ablation using low-intensity ultrasound and sound excitable drug.

scientific article published on 9 May 2017

Ultra Pseudo-Stokes Shift Near Infrared Dyes Based on Energy Transfer

scientific article published on February 2013

Using an RNA aptamer probe for flow cytometry detection of CD30-expressing lymphoma cells.

scientific article published on 12 October 2009

Using oligonucleotide aptamer probes for immunostaining of formalin-fixed and paraffin-embedded tissues

scientific article

Versatile Nanodelivery Platform to Maximize siRNA Combination Therapy

scientific article published on 22 September 2016

siRNA Nanoparticles for Ultra-Long Gene Silencing In Vivo.

scientific article published on January 2016