List of works - Sandra M. Cardoso

A cybrid cell model for the assessment of the link between mitochondrial deficits and sporadic Parkinson's disease

scientific article

Activation of the endoplasmic reticulum stress response by the amyloid-beta 1-40 peptide in brain endothelial cells.

scientific article published on 28 August 2013

Alzheimer's disease-associated neurotoxic mechanisms and neuroprotective strategies.

scientific article

Amyloid β-induced ER stress is enhanced under mitochondrial dysfunction conditions.

scientific article published on 25 June 2011

Amyloid-beta disrupts calcium and redox homeostasis in brain endothelial cells

scientific article published on 16 May 2014

Amyloid-β-induced mitochondrial dysfunction impairs the autophagic lysosomal pathway in a tubulin dependent pathway

scientific article published on January 2011

Apoptotic cell death induced by hydrogen peroxide in NT2 parental and mitochondrial DNA depleted cells

scientific article published on October 2004

Bifunctional phenolic-choline conjugates as anti-oxidants and acetylcholinesterase inhibitors

scientific article published on 11 November 2010

Bioenergetic flux, mitochondrial mass and mitochondrial morphology dynamics in AD and MCI cybrid cell lines

scientific article published on 4 June 2013

Calpain-mediated MPP+ toxicity in mitochondrial DNA depleted cells

scientific article

Cross-talk between mitochondria and proteasome in Parkinson's disease pathogenesis

scientific article published on 21 May 2010

Cyanide preconditioning protects brain endothelial and NT2 neuron-like cells against glucotoxicity: role of mitochondrial reactive oxygen species and HIF-1α

scientific journal article

Cytochrome c oxidase is decreased in Alzheimer's disease platelets

scientific article published in January 2004

Design, synthesis and neuroprotective evaluation of novel tacrine-benzothiazole hybrids as multi-targeted compounds against Alzheimer's disease.

scientific article published on 24 May 2013

Donepezil structure-based hybrids as potential multifunctional anti-Alzheimer's drug candidates

scientific article published on 01 December 2018

Dysfunctional mitochondria uphold calpain activation: contribution to Parkinson's disease pathology

scientific article

ER stress-mediated apoptotic pathway induced by Abeta peptide requires the presence of functional mitochondria.

scientific article

Effects of mild running on substantia nigra during early neurodegeneration.

scientific article published on 12 September 2017

Endoplasmic reticulum and mitochondria interplay mediates apoptotic cell death: relevance to Parkinson's disease

scientific article published on 16 April 2009

Glutathione cycle impairment mediates A beta-induced cell toxicity

scientific article published in March 2003

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

HIV Infection Is Not Associated With Aortic Stiffness. Traditional Cardiovascular Risk Factors Are the Main Determinants-Cross-sectional Results of INI-ELSA-BRASIL.

scientific article

HIV testing and the care continuum among transgender women: population estimates from Rio de Janeiro, Brazil

scientific article published on September 2017

Hydroxypyridinone-benzofuran hybrids with potential protective roles for Alzheimer´s disease therapy

scientific article published on 21 November 2017

Inhibition of NF-kB Renders Cells more Vulnerable to Apoptosis Induced by Amyloid ß Peptides

scientific article published on September 2003

Inhibition of NF-kB renders cells more vulnerable to apoptosis induced by amyloid beta peptides

scientific article published in September 2003

Involvement of mitochondria in endoplasmic reticulum stress-induced apoptotic cell death pathway triggered by the prion peptide PrP(106-126).

scientific article published on 6 November 2007

LRRK2 at the Crossroad Between Autophagy and Microtubule Trafficking: Insights into Parkinson's Disease.

scientific article

LRRK2, a puzzling protein: insights into Parkinson's disease pathogenesis

scientific article

Loss of proteostasis induced by amyloid beta peptide in brain endothelial cells

scientific article published on 28 February 2014

Mechanisms of the deleterious effects of tamoxifen on mitochondrial respiration rate and phosphorylation efficiency

scientific article published in November 2001

Microbial BMAA elicits mitochondrial dysfunction, innate immunity activation, and Alzheimer's disease features in cortical neurons

scientific article published on 05 November 2020

Mitochondria and ubiquitin-proteasomal system interplay: relevance to Parkinson's disease

scientific article

Mitochondria as a therapeutic target in Alzheimer's disease and diabetes

scientific article published on December 2009

Mitochondria drive autophagy pathology via microtubule disassembly: a new hypothesis for Parkinson disease

scientific article published on 17 October 2012

Mitochondria dysfunction of Alzheimer's disease cybrids enhances Abeta toxicity

scientific article

Mitochondria: the common upstream driver of amyloid-β and tau pathology in Alzheimer's disease.

scientific article published on August 2011

Mitochondrial Dysfunction: The Road to Alpha-Synuclein Oligomerization in PD.

scientific article published on 16 January 2011

Mitochondrial Metabolic Control of Microtubule Dynamics Impairs the Autophagic Pathway in Parkinson’s Disease ⬇️

scientific article published on 09 December 2011

Mitochondrial Metabolism Power SIRT2-Dependent Deficient Traffic Causing Alzheimer's-Disease Related Pathology

scientific article published on 17 June 2016

Mitochondrial Metabolism Regulates Microtubule Acetylome and Autophagy Trough Sirtuin-2: Impact for Parkinson's Disease

scientific article

Mitochondrial abnormalities in Alzheimer's disease: possible targets for therapeutic intervention

scientific article

Mitochondrial dynamics and neuronal fate in Parkinson's disease.

scientific article published on 17 May 2012

Mitochondrial dysfunction and caspase activation in rat cortical neurons treated with cocaine or amphetamine

scientific article published on 25 April 2006

Mitochondrial function in Parkinson's disease cybrids containing an nt2 neuron-like nuclear background.

scientific article

Mitochondrial function is differentially affected upon oxidative stress

scientific article

Mitochondrial fusion/fission, transport and autophagy in Parkinson's disease: when mitochondria get nasty.

scientific article published on 20 February 2011

Mitochondrial metabolism in Parkinson's disease impairs quality control autophagy by hampering microtubule-dependent traffic

scientific article

Mitochondrial respiration and respiration-associated proteins in cell lines created through Parkinson's subject mitochondrial transfer

scientific article

Mitochondrial-dependent apoptosis in Huntington's disease human cybrids.

scientific article

Molecular Pathways of Mitochondrial Dysfunction in Neurodegeneration: the Paradigms of Parkinson's and Huntington's Diseases

scholarly article published 2007

Multifunctional iron-chelators with protective roles against neurodegenerative diseases.

scientific article published on 13 March 2013

Neurodegenerative pathways in Parkinson's disease: therapeutic strategies

scientific article

New Multitarget Hybrids Bearing Tacrine and Phenylbenzothiazole Motifs as Potential Drug Candidates for Alzheimer's Disease

scientific article published on 07 February 2019

New Tacrine Hybrids with Natural-Based Cysteine Derivatives as Multitargeted Drugs for Potential Treatment of Alzheimer's Disease

scientific article published on 8 August 2015

Novel tacrine-benzofuran hybrids as potential multi-target drug candidates for the treatment of Alzheimer's Disease

scientific article published on 01 December 2020

Oxidative stress involvement in alpha-synuclein oligomerization in Parkinson's disease cybrids

scientific article

Polymorphic variation in cytochrome oxidase subunit genes

scientific article

Prodromal metabolic phenotype in MCI cybrids: implications for Alzheimer's disease.

scientific article

Protective effect of zinc on amyloid-beta 25-35 and 1-40 mediated toxicity.

scientific article published on January 2005

SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization

scientific article

Special Focus on Autophagy

scholarly article by Sandra M. Cardoso published in April 2015

Tacrine-deferiprone hybrids as multi-target-directed metal chelators against Alzheimer's disease: a two-in-one drug

scientific article published on 05 September 2018

The Impact of Mitochondrial Fusion and Fission Modulation in Sporadic Parkinson's Disease.

scientific article

The Role of Beclin-1 Acetylation on Autophagic Flux in Alzheimer's Disease

scientific article published on 19 January 2019

The Upshot of LRRK2 Inhibition to Parkinson's Disease Paradigm

scientific article published on 15 November 2014

The mitochondrial cascade hypothesis for Parkinson's disease

scientific article published on January 2011

The protective effect of vitamin E, idebenone and reduced glutathione on free radical mediated injury in rat brain synaptosomes.

scientific article published in May 1998

The rescue of microtubule-dependent traffic recovers mitochondrial function in Parkinson's disease

scientific article published on 11 October 2013

The role of calcineurin in amyloid-beta-peptides-mediated cell death

scientific article published on July 2005

The role of endoplasmic reticulum in amyloid precursor protein processing and trafficking: implications for Alzheimer's disease.

scientific article published on 14 May 2014

Therapeutic intervention at cellular quality control systems in Alzheimer's and Parkinson's diseases

scientific article published on January 2011

Ubiquitin proteasome system in Parkinson's disease: a keeper or a witness?

scientific article

List of works by Sandra M. Cardoso

A cybrid cell model for the assessment of the link between mitochondrial deficits and sporadic Parkinson's disease

Activation of the endoplasmic reticulum stress response by the amyloid-beta 1-40 peptide in brain endothelial cells.

Alzheimer's disease-associated neurotoxic mechanisms and neuroprotective strategies.

Amyloid β-induced ER stress is enhanced under mitochondrial dysfunction conditions.

Amyloid-beta disrupts calcium and redox homeostasis in brain endothelial cells

Amyloid-β-induced mitochondrial dysfunction impairs the autophagic lysosomal pathway in a tubulin dependent pathway

Apoptotic cell death induced by hydrogen peroxide in NT2 parental and mitochondrial DNA depleted cells

Bifunctional phenolic-choline conjugates as anti-oxidants and acetylcholinesterase inhibitors

Bioenergetic flux, mitochondrial mass and mitochondrial morphology dynamics in AD and MCI cybrid cell lines

Calpain-mediated MPP+ toxicity in mitochondrial DNA depleted cells

Cross-talk between mitochondria and proteasome in Parkinson's disease pathogenesis

Cyanide preconditioning protects brain endothelial and NT2 neuron-like cells against glucotoxicity: role of mitochondrial reactive oxygen species and HIF-1α

Cytochrome c oxidase is decreased in Alzheimer's disease platelets

Design, synthesis and neuroprotective evaluation of novel tacrine-benzothiazole hybrids as multi-targeted compounds against Alzheimer's disease.

Donepezil structure-based hybrids as potential multifunctional anti-Alzheimer's drug candidates

Dysfunctional mitochondria uphold calpain activation: contribution to Parkinson's disease pathology

ER stress-mediated apoptotic pathway induced by Abeta peptide requires the presence of functional mitochondria.

Effects of mild running on substantia nigra during early neurodegeneration.

Endoplasmic reticulum and mitochondria interplay mediates apoptotic cell death: relevance to Parkinson's disease

Glutathione cycle impairment mediates A beta-induced cell toxicity

Guidelines for the use and interpretation of assays for monitoring autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

HIV Infection Is Not Associated With Aortic Stiffness. Traditional Cardiovascular Risk Factors Are the Main Determinants-Cross-sectional Results of INI-ELSA-BRASIL.

HIV testing and the care continuum among transgender women: population estimates from Rio de Janeiro, Brazil

Hydroxypyridinone-benzofuran hybrids with potential protective roles for Alzheimer´s disease therapy

Inhibition of NF-kB Renders Cells more Vulnerable to Apoptosis Induced by Amyloid ß Peptides

Inhibition of NF-kB renders cells more vulnerable to apoptosis induced by amyloid beta peptides

Involvement of mitochondria in endoplasmic reticulum stress-induced apoptotic cell death pathway triggered by the prion peptide PrP(106-126).

LRRK2 at the Crossroad Between Autophagy and Microtubule Trafficking: Insights into Parkinson's Disease.

LRRK2, a puzzling protein: insights into Parkinson's disease pathogenesis

Loss of proteostasis induced by amyloid beta peptide in brain endothelial cells

Mechanisms of the deleterious effects of tamoxifen on mitochondrial respiration rate and phosphorylation efficiency

Microbial BMAA elicits mitochondrial dysfunction, innate immunity activation, and Alzheimer's disease features in cortical neurons

Mitochondria and ubiquitin-proteasomal system interplay: relevance to Parkinson's disease

Mitochondria as a therapeutic target in Alzheimer's disease and diabetes

Mitochondria drive autophagy pathology via microtubule disassembly: a new hypothesis for Parkinson disease

Mitochondria dysfunction of Alzheimer's disease cybrids enhances Abeta toxicity

Mitochondria: the common upstream driver of amyloid-β and tau pathology in Alzheimer's disease.

Mitochondrial Dysfunction: The Road to Alpha-Synuclein Oligomerization in PD.

Mitochondrial Metabolic Control of Microtubule Dynamics Impairs the Autophagic Pathway in Parkinson’s Disease ⬇️

Mitochondrial Metabolism Power SIRT2-Dependent Deficient Traffic Causing Alzheimer's-Disease Related Pathology

Mitochondrial Metabolism Regulates Microtubule Acetylome and Autophagy Trough Sirtuin-2: Impact for Parkinson's Disease

Mitochondrial abnormalities in Alzheimer's disease: possible targets for therapeutic intervention

Mitochondrial dynamics and neuronal fate in Parkinson's disease.

Mitochondrial dysfunction and caspase activation in rat cortical neurons treated with cocaine or amphetamine

Mitochondrial function in Parkinson's disease cybrids containing an nt2 neuron-like nuclear background.

Mitochondrial function is differentially affected upon oxidative stress

Mitochondrial fusion/fission, transport and autophagy in Parkinson's disease: when mitochondria get nasty.

Mitochondrial metabolism in Parkinson's disease impairs quality control autophagy by hampering microtubule-dependent traffic

Mitochondrial respiration and respiration-associated proteins in cell lines created through Parkinson's subject mitochondrial transfer

Mitochondrial-dependent apoptosis in Huntington's disease human cybrids.

Molecular Pathways of Mitochondrial Dysfunction in Neurodegeneration: the Paradigms of Parkinson's and Huntington's Diseases

Multifunctional iron-chelators with protective roles against neurodegenerative diseases.

Neurodegenerative pathways in Parkinson's disease: therapeutic strategies

New Multitarget Hybrids Bearing Tacrine and Phenylbenzothiazole Motifs as Potential Drug Candidates for Alzheimer's Disease

New Tacrine Hybrids with Natural-Based Cysteine Derivatives as Multitargeted Drugs for Potential Treatment of Alzheimer's Disease

Novel tacrine-benzofuran hybrids as potential multi-target drug candidates for the treatment of Alzheimer's Disease

Oxidative stress involvement in alpha-synuclein oligomerization in Parkinson's disease cybrids

Polymorphic variation in cytochrome oxidase subunit genes

Prodromal metabolic phenotype in MCI cybrids: implications for Alzheimer's disease.

Protective effect of zinc on amyloid-beta 25-35 and 1-40 mediated toxicity.

SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization

Special Focus on Autophagy

Tacrine-deferiprone hybrids as multi-target-directed metal chelators against Alzheimer's disease: a two-in-one drug

The Impact of Mitochondrial Fusion and Fission Modulation in Sporadic Parkinson's Disease.

The Role of Beclin-1 Acetylation on Autophagic Flux in Alzheimer's Disease

The Upshot of LRRK2 Inhibition to Parkinson's Disease Paradigm

The mitochondrial cascade hypothesis for Parkinson's disease

The protective effect of vitamin E, idebenone and reduced glutathione on free radical mediated injury in rat brain synaptosomes.

The rescue of microtubule-dependent traffic recovers mitochondrial function in Parkinson's disease

The role of calcineurin in amyloid-beta-peptides-mediated cell death

The role of endoplasmic reticulum in amyloid precursor protein processing and trafficking: implications for Alzheimer's disease.

Therapeutic intervention at cellular quality control systems in Alzheimer's and Parkinson's diseases

Ubiquitin proteasome system in Parkinson's disease: a keeper or a witness?