List of works by Serge Muyldermans

A DNA Sequence for Positioning Chromatosomes

scientific article published on 01 April 1996

A Nanobody Binding to Non-Amyloidogenic Regions of the Protein Human Lysozyme Enhances Partial Unfolding but Inhibits Amyloid Fibril Formation

scientific article

A bacterial-two-hybrid selection system for one-step isolation of intracellularly functional Nanobodies

scientific article

A bispecific nanobody to provide full protection against lethal scorpion envenoming

article published in 2010

A camelid antibody candidate for development of a therapeutic agent against Hemiscorpius lepturus envenomation

scientific article

A camelid antibody fragment inhibits the formation of amyloid fibrils by human lysozyme

scientific article

A case of convergence: why did a simple alternative to canonical antibodies arise in sharks and camels?

scientific article

A general protocol for the generation of Nanobodies for structural biology

scientific article

A nanobody-based electrochemiluminescent immunosensor for sensitive detection of human procalcitonin.

scientific article

A nanobody-based tracer targeting DPP6 for non-invasive imaging of human pancreatic endocrine cells.

scientific article published on 9 November 2017

A novel promiscuous class of camelid single-domain antibody contributes to the antigen-binding repertoire

scientific article

A recombinant dromedary antibody fragment (VHH or nanobody) directed against human Duffy antigen receptor for chemokines

scientific article

A simple quantitative affinity capturing assay of poliovirus antigens and subviral particles by single-domain antibodies using magnetic beads

scientific article published in March 2011

A single-domain antibody fragment in complex with RNase A: non-canonical loop structures and nanomolar affinity using two CDR loops

scientific article

A synthetic camel anti-lysozyme peptide antibody (peptibody) with flexible loop structure identified by high-resolution affinity mass spectrometry

scientific article

A versatile nanotrap for biochemical and functional studies with fluorescent fusion proteins

scientific article

Affinity is an important determinant of the anti-trypanosome activity of nanobodies

scientific article

An S-layer heavy chain camel antibody fusion protein for generation of a nanopatterned sensing layer to detect the prostate-specific antigen by surface plasmon resonance technology

scientific article

Antibody Fragments as Probe in Biosensor Development

scientific article published on 8 August 2008

Antibody repertoire development in camelids

scientific article

Antigen Binding and Solubility Effects upon the Veneering of a Camel VHH in Framework-2 to Mimic a VH

scientific article published on 01 July 2005

Antigen specificity and high affinity binding provided by one single loop of a camel single-domain antibody

scientific article

Assembly of oligonucleosomes into a limit series of multimeric higher-order chromatin structures

scientific article published in 1985

Bacterial two hybrid: a versatile one-step intracellular selection method.

scientific article

Beta-lactamase inhibitors derived from single-domain antibody fragments elicited in the camelidae

scientific article

Camel heavy-chain antibodies: diverse germline V(H)H and specific mechanisms enlarge the antigen-binding repertoire

scientific article published on March 2000

Camel single-domain antibody inhibits enzyme by mimicking carbohydrate substrate

scientific article

Camelid immunoglobulins and nanobody technology.

scientific article published on 17 October 2008

Camelid nanobodies raised against an integral membrane enzyme, nitric oxide reductase

scientific article

Camelid nanobodies with high affinity for broad bean mottle virus: a possible promising tool to immunomodulate plant resistance against viruses

scientific article published on 4 February 2015

Camelid single-domain antibody-fragment engineering for (pre)clinical in vivo molecular imaging applications: adjusting the bullet to its target

scientific article published on 16 May 2013

Canonical antigen-binding loop structures in immunoglobulins: more structures, more canonical classes?

scientific article

Chaperonin GroEL a Brucella immunodominant antigen identified using Nanobody and MALDI-TOF-MS technologies

scientific article

Chemical basis for the affinity maturation of a camel single domain antibody

scientific article published on 21 September 2004

Chromosome rearrangement in Leishmania mexicana M379

scientific article published on 01 May 1991

Cloning and characterization of the dromedary (Camelus dromedarius) neonatal Fc receptor (drFcRn).

scientific article published on 24 March 2006

Comparative filter binding study of H5 to nucleosome core particles, H1, H5 depleted chromatosomes and DNA fragments

scientific article published on 01 January 1988

Comparison of llama VH sequences from conventional and heavy chain antibodies

scientific article published on 01 November 1997

Correlation between epidermal growth factor receptor-specific nanobody uptake and tumor burden: a tool for noninvasive monitoring of tumor response to therapy

scientific article published on October 2011

Crystal structure of a camel single-domain VH antibody fragment in complex with lysozyme

scientific article

Crystal structure of the intrinsically flexible addiction antidote MazE

scientific article (publication date: 25 July 2003)

DNA Sequence Organization in Chromatosomes

DNA recombination associated with short direct repeats in Leishmania mexicana M379.

scientific article

Degenerate interfaces in antigen-antibody complexes

scientific article

Development and Characterization of Nanobodies Targeting the Kupffer Cell

scientific article published on 22 February 2021

Development of 177Lu-nanobodies for radioimmunotherapy of HER2-positive breast cancer: evaluation of different bifunctional chelators

scientific article

Development of Cys38 knock-out and humanized version of NbAahII10 nanobody with improved neutralization of AahII scorpion toxin

scientific article published on 28 July 2011

Development of VEGFR2-specific Nanobody Pseudomonas exotoxin A conjugated to provide efficient inhibition of tumor cell growth

scientific article published on 29 September 2012

Development of a Nanobody-based lateral flow assay to detect active Trypanosoma congolense infections.

scientific article

Development of a high affinity Affibody-derived protein against amyloid β-peptide for future Alzheimer's disease therapy

scientific article published on 10 September 2015

Differences in rearrangements of H1 and H5 in chicken erythrocyte chromatin

scientific article published on 01 March 1981

Different residues in periplasmic domains of the CcmC inner membrane protein of Pseudomonas fluorescens ATCC 17400 are critical for cytochrome c biogenesis and pyoverdine-mediated iron uptake

scientific article published on 01 November 1998

Differential association of linker histones H1 and H5 with telomeric nucleosomes in chicken erythrocytes

scientific article published on December 1994

Direct injection of functional single-domain antibodies from E. coli into human cells

scientific article

Disulfide bond introduction for general stabilization of immunoglobulin heavy-chain variable domains

scientific article published on 16 January 2008

Dual beneficial effect of interloop disulfide bond for single domain antibody fragments

scientific article published on 29 November 2011

Efficient cancer therapy with a nanobody-based conjugate

scientific article

Efficient targeting of conserved cryptic epitopes of infectious agents by single domain antibodies. African trypanosomes as paradigm

scientific article

Efficient tumor targeting by single-domain antibody fragments of camels

scientific article published on March 2002

Emergence and evolution of functional heavy-chain antibodies in Camelidae

scientific article

Engineering a camelid antibody fragment that binds to the active site of human lysozyme and inhibits its conversion into amyloid fibrils

scientific article published on 25 September 2008

Engineering camel single-domain antibodies and immobilization chemistry for human prostate-specific antigen sensing

scientific article

Epitope structure and binding affinity of single chain llama anti-β-amyloid antibodies revealed by proteolytic excision affinity-mass spectrometry

scientific article

Evaluation of a nanobody phage display library constructed from a Brucella-immunised camel.

scientific article

Expanded target and cofactor repertoire for the transcriptional activator LysM from Sulfolobus

scientific article published on 25 January 2013

Expression, purification and X-ray crystallographic analysis of the Helicobacter pylori blood group antigen-binding adhesin BabA.

scientific article

General strategy to humanize a camelid single-domain antibody and identification of a universal humanized nanobody scaffold

scientific article

Generation and characterization of a functional Nanobody against the vascular endothelial growth factor receptor-2; angiogenesis cell receptor

scientific article

Generation and characterization of inhibitory nanobodies towards thrombin activatable fibrinolysis inhibitor

scientific article published on 17 February 2010

Generation and characterization of nanobodies targeting PSMA for molecular imaging of prostate cancer.

scientific article published in May 2014

Generation and characterization of non-competitive furin-inhibiting nanobodies

scientific article published on November 2012

Generation and design of nanobodies

scientific article published on 11 August 2020

Generation of VHH antibodies against the Arabidopsis thaliana seed storage proteins

scientific article

Generation of a functional monomolecular protein lattice consisting of an s-layer fusion protein comprising the variable domain of a camel heavy chain antibody.

scientific article published in March 2003

Generation of a nanobody targeting the paraflagellar rod protein of trypanosomes

scientific article

Generation of anti-infectome/anti-proteome nanobodies

scientific article

Guided Evolution of Recombinant Acetylcholinesterase II by Homology Modeling to Change Pesticide Sensitivity

scientific article published on 27 October 2018

Heating as a rapid purification method for recovering correctly-folded thermotolerant VH and VHH domains

scientific article

Heavy-chain antibodies in Camelidae; a case of evolutionary innovation

scientific article published on 26 February 2002

Heavy-chain only antibodies derived from dromedary are secreted and displayed by mouse B cells

High affinity nanobodies against the Trypanosome brucei VSG are potent trypanolytic agents that block endocytosis

scientific article

Homo- and heteronuclear two-dimensional NMR studies of the globular domain of histone H1: Sequential assignment and secondary structure

scientific article (publication date: October 1993)

Homo- and heteronuclear two-dimensional NMR studies of the globular domain of histone H1: full assignment, tertiary structure, and comparison with the globular domain of histone H5

scientific article

Identification of Nanobodies against the Acute Myeloid Leukemia Marker CD33

scientific article published on 02 January 2020

Identification of New DR5 Agonistic Nanobodies and Generation of Multivalent Nanobody Constructs for Cancer Treatment

scientific article published on 27 September 2019

Identification of a novel, nanobody-induced, mechanism of TAFI inactivation and its in vivo application.

scientific article published in February 2014

Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies.

scientific article

Identification of potent nanobodies to neutralize the most poisonous polypeptide from scorpion venom

scientific article published in 2009

Imaging and radioimmunotherapy of multiple myeloma with anti-idiotypic Nanobodies

scientific article published on 9 October 2013

In vitro analysis and in vivo tumor targeting of a humanized, grafted nanobody in mice using pinhole SPECT/micro-CT.

scientific article published on 16 June 2010

In vitro and in vivo characterisation of the profibrinolytic effect of an inhibitory anti-rat TAFI nanobody

scientific article published on 09 January 2014

In vitro antiviral activity of single domain antibody fragments against poliovirus

scientific article published on 08 June 2010

Increased Expression of Adherens Junction Components in Mouse Liver following Bile Duct Ligation

scientific article published on 22 October 2019

Influence of histones H1/H5 on the DNA coiling in the nucleosome — electric dichroism and birefringence study

scientific article published in 1981

Inhibiting the Ca2+ Influx Induced by Human CSF.

scientific article published in December 2017

Interactions between metal-binding domains modulate intracellular targeting of Cu(I)-ATPase ATP7B, as revealed by nanobody binding

scientific article

Introduction to heavy chain antibodies and derived Nanobodies.

scientific article published on January 2012

Isolation and characterization of single-chain Fv genes encoding antibodies specific for Drosophila Poxn protein.

scientific article published in October 1998

Kinetic and affinity predictions of a protein-protein interaction using multivariate experimental design

scientific article

Limitations of the poly(glutamic acid) reconstitution method in the reassembly of mono- and dinucleosomes

scientific article published in September 1986

Localization, mechanism and reduction of renal retention of technetium-99m labeled epidermal growth factor receptor-specific nanobody in mice.

scientific article

Minimum information about a protein affinity reagent (MIAPAR)

scientific article published on 01 July 2010

Modulation of protein properties in living cells using nanobodies

scientific article

Molecular Imaging with Kupffer Cell-Targeting Nanobodies for Diagnosis and Prognosis in Mouse Models of Liver Pathogenesis.

scientific article published on 23 June 2016

Molecular analysis of heavy chain-only antibodies of Camelus bactrianus

scientific article published in December 2014

Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies

scholarly article

Molecular imaging with macrophage CRIg-targeting nanobodies for early and preclinical diagnosis in a mouse model of rheumatoid arthritis.

scientific article published on 31 March 2014

Monitoring liver macrophages using nanobodies targeting Vsig4: Concanavalin A induced acute hepatitis as paradigm

scientific article published on 02 October 2014

NIRF-Molecular Imaging with Synovial Macrophages-Targeting Vsig4 Nanobody for Disease Monitoring in a Mouse Model of Arthritis

scientific article published on 08 July 2019

Nanobodies against the metal binding domains of ATP7B as tools to study copper transport in the cell

scientific article published on 23 October 2020

Nanobodies and recombinant binders in cell biology

scientific article

Nanobodies and their potential applications

scientific article published in June 2013

Nanobodies as novel agents for cancer therapy

scientific article

Nanobodies as tools for in vivo imaging of specific immune cell types

scientific article published on 15 April 2010

Nanobodies targeting mouse/human VCAM1 for the nuclear imaging of atherosclerotic lesions

scientific article published on March 2012

Nanobodies, a promising tool for species-specific diagnosis of Taenia solium cysticercosis

scientific article

Nanobodies: natural single-domain antibodies

scientific article

Nanobodies®: proficient tools in diagnostics

scientific article published on September 2010

Nanobody(R)-based chromatin immunoprecipitation/micro-array analysis for genome-wide identification of transcription factor DNA binding sites

scientific article published on 28 December 2012

Nanobody-based chromatin immunoprecipitation.

scientific article published in January 2012

Nanobody-based products as research and diagnostic tools

scientific article published on April 2014

Nanobody-coupled microbubbles as novel molecular tracer

scientific article

Nanoimmunoassay onto a screen printed electrode for HER2 breast cancer biomarker determination

scientific article published on 7 July 2014

Naturally occurring antibodies devoid of light chains

scientific article

Neutron scattering of chromatin multinucleosomes

article

Neutron scattering studies of chromatosomes

article

Parallel selection of multiple anti-infectome Nanobodies without access to purified antigens

scientific article

Pharmacokinetics of radiolabeled dimeric sdAbs constructs targeting human CD20

scholarly article by Ahmet Krasniqi published in October 2018

Position and orientation of the globular domain of linker histone H5 on the nucleosome.

scientific article

Potent enzyme inhibitors derived from dromedary heavy-chain antibodies

scientific article published on July 1998

Pre-clinical studies of toxin-specific nanobodies: evidence of in vivo efficacy to prevent fatal disturbances provoked by scorpion envenoming

scientific article published on 11 August 2012

Preclinical screening of anti-HER2 nanobodies for molecular imaging of breast cancer

scientific article

Preparation and purification of mononucleosome particles containing histone H5

scientific article published on 01 September 1980

Prostate-specific antigen immunosensing based on mixed self-assembled monolayers, camel antibodies and colloidal gold enhanced sandwich assays

scientific article published on 25 December 2004

Protection of discrete DNA fragments by the complex H1-octamerhistones or H5-octamerhistones after micrococcal nuclease digestion

scientific article

ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome

article

Putative regulatory sequences for the transcription of mini-exons in Trypanosoma brucei as revealed by S1 sensitivity

scientific article published in January 1985

Radiolabeled nanobodies as theranostic tools in targeted radionuclide therapy of cancer

scientific article published on 18 July 2014

Recent developments in engineering and delivery of protein and antibody therapeutics

Reduced global cooperativity is a common feature underlying the amyloidogenicity of pathogenic lysozyme mutations

Resolution of an immunodiagnostic dilemma: heavy chain chimeric antibodies for species in which plasmocytomas are unknown

scientific article published on 21 August 2012

Scatter analysis of discrete-sized chromatin fragments favours a cylindrical organization

scientific article published in September 1985

Selection and identification of single domain antibody fragments from camel heavy-chain antibodies

scientific article (publication date: 15 September 1997)

Sequence and structure of VH domain from naturally occurring camel heavy chain immunoglobulins lacking light chains

scientific article

Single domain antibodies derived from dromedary lymph node and peripheral blood lymphocytes sensing conformational variants of prostate-specific antigen

scientific article

Single domain antibodies: comparison of camel VH and camelised human VH domains

scientific article

Single domain camel antibodies: current status.

scientific article

Single-domain antibodies as building blocks for novel therapeutics

scientific article

Single-domain antibodies targeting neuraminidase protect against an H5N1 influenza virus challenge

scientific article published on 14 May 2014

Single-domain antibody fragments with high conformational stability

scientific article published on March 2002

Site-specific labeling of cysteine-tagged camelid single-domain antibody-fragments for use in molecular imaging

scientific article published on 9 May 2014

Soluble aggregates present in cerebrospinal fluid change in size and mechanism of toxicity during Alzheimer's disease progression

scientific article published on 26 July 2019

Sortase A-mediated site-specific labeling of camelid single-domain antibody-fragments: a versatile strategy for multiple molecular imaging modalities.

scientific article published on 5 May 2016

Specific cell targeting with nanobody conjugated branched gold nanoparticles for photothermal therapy

scientific article (publication date: 28 June 2011)

Specific targeting of atherosclerotic plaques in ApoE(-/-) mice using a new Camelid sdAb binding the vulnerable plaque marker LOX-1.

scientific article

Specificity Evaluation and Disease Monitoring in Arthritis Imaging with Complement Receptor of the Ig superfamily targeting Nanobodies

scientific article published on 25 October 2016

Strongin VivoMaturation Compensates for Structurally Restricted H3 Loops in Antibody Repertoires

scientific article published in Journal of Biological Chemistry

Structural Basis for the Specific Neutralization of Stx2a with a Camelid Single Domain Antibody Fragment.

scientific article published in March 2018

Structural basis of nanobody recognition of grapevine fanleaf virus and of virus resistance loss

scientific article published on 05 May 2020

Structure of cyclin G-associated kinase (GAK) trapped in different conformations using nanobodies

scientific article

Surface display of a single-domain antibody library on Gram-positive bacteria.

scientific article

Synthesis, preclinical validation, dosimetry, and toxicity of 68Ga-NOTA-anti-HER2 Nanobodies for iPET imaging of HER2 receptor expression in cancer

scientific article published on 13 March 2013

TAFIa inhibiting nanobodies as profibrinolytic tools and discovery of a new TAFIa conformation.

scientific article

TRIM28 and β-actin identified via nanobody-based reverse proteomics approach as possible human glioblastoma biomarkers

scientific article

Targeted alpha therapy using short-lived alpha-particles and the promise of nanobodies as targeting vehicle.

scientific article published on 04 May 2016

Targeted radionuclide therapy with A 177Lu-labeled anti-HER2 nanobody

scientific article

Targeting and tracing antigens in live cells with fluorescent nanobodies

scientific article

The Therapeutic Potential of Nanobodies

scientific article published on 01 February 2020

The crystal structure of recombinant rat pancreatic RNase A

scientific article

The genome-wide binding profile of the Sulfolobus solfataricus transcription factor Ss-LrpB shows binding events beyond direct transcription regulation

scientific article

The regulated expression of an intrabody produces a mutant phenotype in Drosophila.

scientific article published in October 1998

The specific variable domain of camel heavy-chain antibodies is encoded in the germline

scientific article

The structural basis of nanobody unfolding reversibility and thermoresistance.

scientific article

The structural organization of dinudeosomes and oligonucleosomes. Electric dichroism and birefringence study ⬇️

scientific article published on November 11, 1981

Theranostic Radiolabeled Anti-CD20 sdAb for Targeted Radionuclide Therapy of Non-Hodgkin Lymphoma.

scientific article published on 20 October 2017

Therapeutic Nanobodies Targeting Cell Plasma Membrane Transport Proteins: A High-Risk/High-Gain Endeavor

scientific article published on 06 January 2021

Three camelid VHH domains in complex with porcine pancreatic alpha-amylase. Inhibition and versatility of binding topology

scientific article

Ultrasensitive Measurement of Ca2+ Influx into Lipid Vesicles Induced by Protein Aggregates

Ultrasensitive Measurement of Ca2+ Influx into Lipid Vesicles Induced by Protein Aggregates.

scientific article

Unique single‐domain antigen binding fragments derived from naturally occurring camel heavy‐chain antibodies

scientific article published on 01 March 1999

Upon the observation of superbeads in chromatin.

scientific article

Using microdialysis to analyse the passage of monovalent nanobodies through the blood-brain barrier

scientific article published on April 2012

V(H)H (nanobody) directed against human glycophorin A: a tool for autologous red cell agglutination assays

scientific article

VHH, bivalent domains and chimeric Heavy chain-only antibodies with high neutralizing efficacy for scorpion toxin AahI'.

scientific article

Wheat germ in vitro translation to produce one of the most toxic sodium channel specific toxins

scientific article published on 29 July 2014

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