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List of works by Nick Devoogdt

(18)F-nanobody for PET imaging of HER2 overexpressing tumors.

scientific article published on 23 January 2016

131I-labeled Anti-HER2 Camelid sdAb as a Theranostic Tool in Cancer Treatment

scientific article published on 27 July 2017

99mTc-cAbVCAM1-5 imaging is a sensitive and reproducible tool for the detection of inflamed atherosclerotic lesions in mice

scientific article published on 25 August 2014

A nanobody-based nuclear imaging tracer targeting dipeptidyl peptidase 6 to determine the mass of human beta cell grafts in mice

scientific article published on 23 December 2019

A nanobody-based tracer targeting DPP6 for non-invasive imaging of human pancreatic endocrine cells.

scientific article published on 9 November 2017

AAV9 delivered bispecific nanobody attenuates amyloid burden in the gelsolin amyloidosis mouse model

scientific article published on 9 June 2017

Al18F-Labeling Of Heat-Sensitive Biomolecules for Positron Emission Tomography Imaging

scientific article published on 14 July 2017

An Efficient Method for Labeling Single Domain Antibody Fragments with F Using Tetrazine- Trans-Cyclooctene Ligation and a Renal Brush Border Enzyme-Cleavable Linker

scientific article published on 14 November 2018

Anti-human PD-L1 Nanobody for Immuno-PET Imaging: Validation of a Conjugation Strategy for Clinical Translation

scientific article published on 29 September 2020

Beyond the Barrier: Targeted Radionuclide Therapy in Brain Tumors and Metastases

scientific article published on 01 August 2019

Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells

scientific article published on 27 January 2016

Camelid reporter gene imaging: a generic method for in vivo cell tracking

scientific article

Camelid single-domain antibody-fragment engineering for (pre)clinical in vivo molecular imaging applications: adjusting the bullet to its target

scientific article published on 16 May 2013

Clinical Translation of [68Ga]Ga-NOTA-anti-MMR-sdAb for PET/CT Imaging of Protumorigenic Macrophages

scientific article published on 01 October 2019

Correlation between epidermal growth factor receptor-specific nanobody uptake and tumor burden: a tool for noninvasive monitoring of tumor response to therapy

scientific article published on October 2011

Cytoplasmic versus periplasmic expression of site-specifically and bioorthogonally functionalized nanobodies using expressed protein ligation.

scientific article published on 23 February 2017

Development and Characterization of Nanobodies Targeting the Kupffer Cell

scientific article published on 22 February 2021

Development and Validation of a Small Single-domain Antibody That Effectively Inhibits Matrix Metalloproteinase 8.

scientific article published on 18 January 2016

Development of 177Lu-nanobodies for radioimmunotherapy of HER2-positive breast cancer: evaluation of different bifunctional chelators

scientific article

Direct fluorine-18 labeling of heat-sensitive biomolecules for positron emission tomography imaging using the Al18F-RESCA method

scientific article published on 01 October 2018

Effect of Dye and Conjugation Chemistry on the Biodistribution Profile of Near-Infrared-Labeled Nanobodies as Tracers for Image-Guided Surgery.

scientific article published on 28 February 2017

Emerging site-specific bioconjugation strategies for radioimmunotracer development.

scientific article published on 27 April 2016

Evaluating a Single Domain Antibody Targeting Human PD-L1 as a Nuclear Imaging and Therapeutic Agent

scientific article published on 21 June 2019

Evaluation of Antiatherogenic Properties of Ezetimibe Using 3H-Labeled Low-Density-Lipoprotein Cholesterol and 99mTc-cAbVCAM1-5 SPECT in ApoE-/- Mice Fed the Paigen Diet

scientific article published on 9 March 2017

Evaluation of [(99m)Tc]Radiolabeled Macrophage Mannose Receptor-Specific Nanobodies for Targeting of Atherosclerotic Lesions in Mice.

scientific article published on 5 September 2017

Fluorine-18 Labeling of the HER2-Targeting Single-Domain Antibody 2Rs15d Using a Residualizing Label and Preclinical Evaluation.

scientific article published on 13 April 2017

Fluorine-18 labeling of an anti-HER2 VHH using a residualizing prosthetic group via a strain-promoted click reaction: Chemistry and preliminary evaluation.

scientific article published on 10 March 2018

Generation and characterization of nanobodies targeting PSMA for molecular imaging of prostate cancer.

scientific article published in May 2014

Generation and characterization of small single domain antibodies inhibiting human tumor necrosis factor receptor 1.

scientific article

Generation of Single Domain Antibody Fragments Derived from Camelids and Generation of Manifold Constructs

scientific article published on January 1, 2012

Identification of Nanobodies against the Acute Myeloid Leukemia Marker CD33

scientific article published on 02 January 2020

Identification of Useful Nanobodies by Phage Display of Immune Single Domain Libraries Derived from Camelid Heavy Chain Antibodies.

scientific article

Imaging and radioimmunotherapy of multiple myeloma with anti-idiotypic Nanobodies

scientific article published on 9 October 2013

Immuno-imaging using nanobodies

scientific article published on 02 July 2011

Improved Debulking of Peritoneal Tumor Implants by Near-Infrared Fluorescent Nanobody Image Guidance in an Experimental Mouse Model.

scientific article published on 31 October 2017

Improved Detection of Molecular Markers of Atherosclerotic Plaques Using Sub-Millimeter PET Imaging

scientific article published on 16 April 2020

Improved tumor targeting of anti-HER2 nanobody through N-succinimidyl 4-guanidinomethyl-3-iodobenzoate radiolabeling

scientific article

In Vivo Assessment of VCAM-1 Expression by SPECT/CT Imaging in Mice Models of Human Triple Negative Breast Cancer

scientific article published on 23 July 2019

In vitro analysis and in vivo tumor targeting of a humanized, grafted nanobody in mice using pinhole SPECT/micro-CT.

scientific article published on 16 June 2010

Increased Expression of Adherens Junction Components in Mouse Liver following Bile Duct Ligation

scientific article published on 22 October 2019

Labeling Single Domain Antibody Fragments with Fluorine-18 Using 2,3,5,6-Tetrafluorophenyl 6-[18F]Fluoronicotinate Resulting in High Tumor-to-Kidney Ratios

scientific article published on 28 November 2018

Limiting the protein corona: A successful strategy for in vivo active targeting of anti-HER2 nanobody-functionalized nanostars

scientific article published on 6 January 2017

Localization, mechanism and reduction of renal retention of technetium-99m labeled epidermal growth factor receptor-specific nanobody in mice.

scientific article

Molecular Imaging with Kupffer Cell-Targeting Nanobodies for Diagnosis and Prognosis in Mouse Models of Liver Pathogenesis.

scientific article published on 23 June 2016

Molecular imaging using Nanobodies: a case study.

scientific article published in January 2012

Molecular imaging with macrophage CRIg-targeting nanobodies for early and preclinical diagnosis in a mouse model of rheumatoid arthritis.

scientific article published on 31 March 2014

Monitoring liver macrophages using nanobodies targeting Vsig4: Concanavalin A induced acute hepatitis as paradigm

scientific article published on 02 October 2014

Nanobodies and their potential applications

scientific article published in June 2013

Nanobodies as tools for in vivo imaging of specific immune cell types

scientific article published on 15 April 2010

Nanobodies targeting mouse/human VCAM1 for the nuclear imaging of atherosclerotic lesions

scientific article published on March 2012

Nanobody-Facilitated Multiparametric PET/MRI Phenotyping of Atherosclerosis

scientific article published on 17 October 2018

Nanobody-based targeting of the macrophage mannose receptor for effective in vivo imaging of tumor-associated macrophages.

scientific article

Nanobody-coupled microbubbles as novel molecular tracer

scientific article

Non-Invasive Imaging of Amyloid Deposits in a Mouse Model of AGel Using (99m)Tc-Modified Nanobodies and SPECT/CT.

scientific article

Non-invasive assessment of murine PD-L1 levels in syngeneic tumor models by nuclear imaging with nanobody tracers

scientific article published on 30 March 2017

Noninvasive Imaging of the Immune Checkpoint LAG-3 Using Nanobodies, from Development to Pre-Clinical Use

scientific article published on 29 September 2019

Noninvasive imaging of the PD-1:PD-L1 immune checkpoint: Embracing nuclear medicine for the benefit of personalized immunotherapy.

scientific article published on 7 June 2018

Novel applications of nanobodies for in vivo bio-imaging of inflamed tissues in inflammatory diseases and cancer.

scientific article published on 21 July 2012

PET Imaging of Macrophage Mannose Receptor-Expressing Macrophages in Tumor Stroma Using 18F-Radiolabeled Camelid Single-Domain Antibody Fragments

scientific article published on 11 June 2015

Pharmacokinetics of radiolabeled dimeric sdAbs constructs targeting human CD20

scholarly article by Ahmet Krasniqi published in October 2018

Phase I Study of 68Ga-HER2-Nanobody for PET/CT Assessment of HER2 Expression in Breast Carcinoma.

scientific article

Preclinical Targeted α- and β--Radionuclide Therapy in HER2-Positive Brain Metastasis Using Camelid Single-Domain Antibodies

scientific article published on 21 April 2020

Preclinical screening of anti-HER2 nanobodies for molecular imaging of breast cancer

scientific article

Radiolabeled nanobodies as theranostic tools in targeted radionuclide therapy of cancer

scientific article published on 18 July 2014

Radiometal-labeled anti-VCAM-1 nanobodies as molecular tracers for atherosclerosis - impact of radiochemistry on pharmacokinetics

scientific article published on 01 February 2019

Rational Design of Nanobody80 Loop Peptidomimetics: Towards Biased β2 Adrenergic Receptor Ligands.

scientific article published on 27 April 2017

Reshaping nanobodies for affinity purification on protein a

scientific article published on 27 January 2020

SPECT imaging of joint inflammation with Nanobodies targeting the macrophage mannose receptor in a mouse model for rheumatoid arthritis

scientific article published on 27 February 2013

Same-Day Imaging Using Small Proteins: Clinical Experience and Translational Prospects in Oncology

scientific article published on 15 March 2018

Secretory leukocyte protease inhibitor in cancer development.

scientific article

Secretory leukocyte protease inhibitor promotes the tumorigenic and metastatic potential of cancer cells

scientific article published on May 5, 2003

Single Domain Antibody-Mediated Blockade of Programmed Death-Ligand 1 on Dendritic Cells Enhances CD8 T-cell Activation and Cytokine Production

scientific article published on 07 August 2019

Site-Selective Functionalization of Nanobodies Using Intein-Mediated Protein Ligation for Innovative Bioconjugation

scientific article published on 01 January 2019

Site-Specific Labeling of His-Tagged Nanobodies with 99mTc: A Practical Guide

scientific article published on 01 January 2012

Site-Specific Radioactive Labeling of Nanobodies

scientific article published on 01 January 2018

Site-specific labeling of cysteine-tagged camelid single-domain antibody-fragments for use in molecular imaging

scientific article published on 9 May 2014

Size and affinity kinetics of nanobodies influence targeting and penetration of solid tumours

scientific article published on 14 November 2019

Sortase A-mediated site-specific labeling of camelid single-domain antibody-fragments: a versatile strategy for multiple molecular imaging modalities.

scientific article published on 5 May 2016

Specific cell targeting with nanobody conjugated branched gold nanoparticles for photothermal therapy

scientific article (publication date: 28 June 2011)

Specific targeting of atherosclerotic plaques in ApoE(-/-) mice using a new Camelid sdAb binding the vulnerable plaque marker LOX-1.

scientific article

Specificity Evaluation and Disease Monitoring in Arthritis Imaging with Complement Receptor of the Ig superfamily targeting Nanobodies

scientific article published on 25 October 2016

Stromal-targeting radioimmunotherapy mitigates the progression of therapy-resistant tumors

scientific article published on 15 October 2019

Surface display of a single-domain antibody library on Gram-positive bacteria.

scientific article

Synthesis, preclinical validation, dosimetry, and toxicity of 68Ga-NOTA-anti-HER2 Nanobodies for iPET imaging of HER2 receptor expression in cancer

scientific article published on 13 March 2013

Targeted Nanobody-Based Molecular Tracers for Nuclear Imaging and Image-Guided Surgery

scientific article published on 11 January 2019

Targeted alpha therapy using short-lived alpha-particles and the promise of nanobodies as targeting vehicle.

scientific article published on 04 May 2016

Targeted radionuclide therapy with A 177Lu-labeled anti-HER2 nanobody

scientific article

Targeting breast carcinoma with radioiodinated anti-HER2 Nanobody

scientific article published on 15 November 2012

Targeting of vascular cell adhesion molecule-1 by 18F-labelled nanobodies for PET/CT imaging of inflamed atherosclerotic plaques

scientific article published on 22 January 2016

The Next-Generation Immune Checkpoint LAG-3 and Its Therapeutic Potential in Oncology: Third Time's a Charm

scientific article published on 23 December 2020

The Road to Personalized Myeloma Medicine: Patient-specific Single-domain Antibodies for Anti-idiotypic Radionuclide Therapy

scientific article published in January 2022

The alarm anti-protease, secretory leukocyte protease inhibitor, is a proliferation and survival factor for ovarian cancer cells

scientific article

The regulated expression of an intrabody produces a mutant phenotype in Drosophila.

scientific article published in October 1998

The tumor-promoting effect of TNF-alpha involves the induction of secretory leukocyte protease inhibitor

scientific article published on 01 December 2006

Theranostic Radiolabeled Anti-CD20 sdAb for Targeted Radionuclide Therapy of Non-Hodgkin Lymphoma.

scientific article published on 20 October 2017

Theranostics in immuno-oncology using nanobody derivatives

scientific article published on 15 October 2019

Therapeutic Nanobodies Targeting Cell Plasma Membrane Transport Proteins: A High-Risk/High-Gain Endeavor

scientific article published on 06 January 2021

Ultrasound Molecular Imaging of Atherosclerosis With Nanobodies: Translatable Microbubble Targeting Murine and Human VCAM (Vascular Cell Adhesion Molecule) 1

scientific article published on 10 October 2019