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List of works by Alexander Hergovich

Ablation of the kinase NDR1 predisposes mice to the development of T cell lymphoma.

scientific article

Centrosome-associated NDR kinase regulates centrosome duplication

scientific article published on February 2007

Constitutively active NDR1-PIF kinase functions independent of MST1 and hMOB1 signalling

scientific article

Differential NDR/LATS interactions with the human MOB family reveal a negative role for human MOB2 in the regulation of human NDR kinases.

scientific article

Downstream of human NDR kinases: impacting on c-myc and p21 protein stability to control cell cycle progression.

scientific article published on 15 June 2011

Generation of stable human cell lines with Tetracycline-inducible (Tet-on) shRNA or cDNA expression

scientific article published on 5 March 2013

High-throughput site-directed mutagenesis in ES cells.

scientific article published in November 2001

Hippo signalling in the G2/M cell cycle phase: Lessons learned from the yeast MEN and SIN pathways ⬇️

scientific article published on April 15, 2012

Human NDR kinases are rapidly activated by MOB proteins through recruitment to the plasma membrane and phosphorylation

scientific article

Human NDR kinases control G(1)/S cell cycle transition by directly regulating p21 stability.

scientific article

MICAL-1 is a negative regulator of MST-NDR kinase signaling and apoptosis

scientific article

MOB control: Reviewing a conserved family of kinase regulators ⬇️

scientific article published on April 21, 2011

Mammalian Hippo signalling: a kinase network regulated by protein-protein interactions

scientific article

Mammalian NDR protein kinases: from regulation to a role in centrosome duplication.

scientific article published on 15 August 2007

Meta-analysis of IDH-mutant cancers identifies EBF1 as an interaction partner for TET2.

scientific article published on January 2013

NDR kinase is activated by RASSF1A/MST1 in response to Fas receptor stimulation and promotes apoptosis

scientific article

Nuclear Dbf2-related protein kinases (NDRs) in isolated cardiac myocytes and the myocardium: activation by cellular stresses and by phosphoprotein serine-/threonine-phosphatase inhibitors

scientific article published in May 2008

OLA1 in centrosome biology alongside the BRCA1/BARD1 complex: looking beyond centrosomes

scientific article

Rassf5 and Ndr kinases regulate neuronal polarity through Par3 phosphorylation in a novel pathway

scientific article published on 13 June 2014

Regulation of NDR protein kinase by hydrophobic motif phosphorylation mediated by the mammalian Ste20-like kinase MST3

scientific article

Regulation of renal epithelial tight junctions by the von Hippel-Lindau tumor suppressor gene involves occludin and claudin 1 and is independent of E-cadherin

scientific article

Relevance of nuclear and cytoplasmic von hippel lindau protein expression for renal carcinoma progression.

scientific article published on September 2003

TAZ-mediated crosstalk between Wnt and Hippo signaling

scientific article published in April 2010

The MST1 and hMOB1 tumor suppressors control human centrosome duplication by regulating NDR kinase phosphorylation

scientific article published on November 2009

The human tumour suppressor LATS1 is activated by human MOB1 at the membrane

scientific article published on 25 April 2006

VHL loss causes spindle misorientation and chromosome instability.

scientific article

YAP-Hippo signalling downstream of leukemia inhibitory factor receptor: implications for breast cancer.

scientific article

hMOB3 modulates MST1 apoptotic signaling and supports tumor growth in glioblastoma multiforme.

scientific article

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