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List of works by Tu'uhevaha J Kaitu'u-Lino

A bioplex analysis of cytokines and chemokines in first trimester maternal plasma to screen for predictors of miscarriage

scientific article

A comparison of sample collection methods for quantifying cell-free fetal neurodevelopment transcripts in amniotic fluid

scientific article

A new role for activin in endometrial repair after menses

scientific article

A wash step at collection of placental biopsies from preeclamptic pregnancies does not adversely affect levels of sFlt-1 or endoglin.

scientific article

ATF3 is a negative regulator of inflammation in human fetal membranes

scientific article

Activating Transcription Factor 3 Is Reduced in Preeclamptic Placentas and Negatively Regulates sFlt-1 (Soluble fms-Like Tyrosine Kinase 1), Soluble Endoglin, and Proinflammatory Cytokines in Placenta.

scientific article

Assessing the sensitivity of placental growth factor and soluble fms-like tyrosine kinase 1 at 36 weeks' gestation to predict small-for-gestational-age infants or late-onset preeclampsia: a prospective nested case-control study

scientific article published on 31 August 2018

Blood-based biomarkers in the maternal circulation associated with fetal growth restriction

scientific article published on 22 July 2019

Characterization of protocols for primary trophoblast purification, optimized for functional investigation of sFlt-1 and soluble endoglin.

scientific article published on 7 October 2014

Chorioamnionitis Occurring in Women With Preterm Rupture of the Fetal Membranes Is Associated With a Dynamic Increase in mRNAs Coding Cytokines in the Maternal Circulation

scientific article published on 23 January 2015

Circulating GATA2 mRNA is decreased among women destined to develop preeclampsia and may be of endothelial origin

scientific article published in Scientific Reports

Circulating adrenomedullin mRNA is decreased in women destined to develop term preeclampsia

scientific article published on 10 February 2019

Claudin-11 expression and localisation is regulated by androgens in rat Sertoli cells in vitro

scientific article published on 01 June 2007

Combining metformin and esomeprazole is additive in reducing sFlt-1 secretion and decreasing endothelial dysfunction - implications for treating preeclampsia.

scientific article published on 21 February 2018

Complex expression patterns support potential roles for maternally derived activins in the establishment of pregnancy in mouse

scientific article published in November 2006

Corin, an enzyme with a putative role in spiral artery remodeling, is up-regulated in late secretory endometrium and first trimester decidua.

scientific article published on 21 February 2013

Disulfiram inhibits placental soluble FMS-like tyrosine kinase-1 and soluble endoglin secretion independent of the proteasome

scientific article published on 21 September 2018

EGFL7 gene expression is regulated by hypoxia in trophoblast and altered in the plasma of patients with early preeclampsia

scientific article published on 05 September 2018

ELABELA/APELA Levels Are Not Decreased in the Maternal Circulation or Placenta among Women with Preeclampsia

scientific article published in August 2018

Effect of sildenafil citrate on circulating levels of sFlt-1 in preeclampsia

scientific article published on 11 April 2018

Effects of Pravastatin on Human Placenta, Endothelium, and Women With Severe Preeclampsia

scientific article published on 27 July 2015

Effects of gefitinib, an epidermal growth factor receptor inhibitor, on human placental cell growth

scientific article published on October 2013

Effects of simvastatin, rosuvastatin and pravastatin on soluble fms-like tyrosine kinase 1 (sFlt-1) and soluble endoglin (sENG) secretion from human umbilical vein endothelial cells, primary trophoblast cells and placenta

scientific article

Epidermal Growth Factor Rescues Endothelial Dysfunction in Primary Human Tissues In Vitro

scientific article published on 5 December 2016

Estrogen Is Not Essential for Full Endometrial Restoration after Breakdown: Lessons from a Mouse Model

scientific article published in October 2007

Evaluation of ADAM-12 as a diagnostic biomarker of ectopic pregnancy in women with a pregnancy of unknown location.

scientific article

Expression of Myostatin in Intrauterine Growth Restriction and Preeclampsia Complicated Pregnancies and Alterations to Cytokine Production by First-Trimester Placental Explants Following Myostatin Treatment

scientific article published on 02 March 2015

Extracellular matrix dynamics in scar-free endometrial repair: perspectives from mouse in vivo and human in vitro studies.

scientific article published on 25 May 2011

Galectin-7 acts as an adhesion molecule during implantation and increased expression is associated with miscarriage.

scientific article published on 24 January 2014

Heme Oxygenase-1 Is Not Decreased in Preeclamptic Placenta and Does Not Negatively Regulate Placental Soluble fms-Like Tyrosine Kinase-1 or Soluble Endoglin Secretion.

scientific article

Human HtrA4 Expression Is Restricted to the Placenta, Is Significantly Up-Regulated in Early-Onset Preeclampsia, and High Levels of HtrA4 Cause Endothelial Dysfunction

scientific article published on 6 May 2015

Identification of Label-Retaining Perivascular Cells in a Mouse Model of Endometrial Decidualization, Breakdown, and Repair1

article

Identifying late-onset fetal growth restriction by measuring circulating placental RNA in the maternal blood at 28 weeks' gestation.

scientific article

Jumonji Domain Containing Protein 6 Is Decreased in Human Preeclamptic Placentas and Regulates sFLT-1 Splice Variant Production.

scientific article published on 27 January 2016

Key players of the necroptosis pathway RIPK1 and SIRT2 are altered in placenta from preeclampsia and fetal growth restriction.

scientific article published on 4 January 2017

Loss of Akt increases soluble endoglin release from endothelial cells but not placenta.

scientific article

MMP-14 Is Expressed in Preeclamptic Placentas and Mediates Release of Soluble Endoglin ⬇️

scientific article published on January 31, 2012

MMP-15 is upregulated in preeclampsia, but does not cleave endoglin to produce soluble endoglin

scientific article

MT-MMPs in pre-eclamptic placenta: relationship to soluble endoglin production

scientific article published on 20 December 2012

Maternal plasma concentrations of the placental specific sFLT-1 variant, sFLT-1 e15a, in fetal growth restriction and preeclampsia.

scientific article

Maternal serum interleukin-33 and soluble ST2 across early pregnancy, and their association with miscarriage ⬇️

scientific article published on July 28, 2012

Measuring thyroid peroxidase antibodies on the day nulliparous women present for management of miscarriage: a descriptive cohort study.

scientific article published on 14 May 2013

Melatonin enhances antioxidant molecules in the placenta, reduces secretion of soluble fms-like tyrosine kinase 1 (sFLT) from primary trophoblast but does not rescue endothelial dysfunction: An evaluation of its potential to treat preeclampsia.

scientific article published on 11 April 2018

Metformin as a prevention and treatment for preeclampsia: effects on soluble fms-like tyrosine kinase 1 and soluble endoglin secretion and endothelial dysfunction.

scientific article published on 22 December 2015

Neutrophil depletion retards endometrial repair in a mouse model

scientific article published on 22 December 2006

Nuclear factor of activated T-cells (NFAT) regulates soluble fms-like tyrosine kinase-1 secretion (sFlt-1) from human placenta.

scientific article published on 21 October 2016

PAPPA2 is increased in severe early onset pre-eclampsia and upregulated with hypoxia

scientific article published on January 2014

PLAC4 is upregulated in severe early onset preeclampsia and upregulated with syncytialisation but not hypoxia

scientific article published on 9 January 2013

PSG7 and 9 (Pregnancy-Specific β-1 Glycoproteins 7 and 9): Novel Biomarkers for Preeclampsia

scientific article published on 24 March 2022

Paternal obesity in a rodent model affects placental gene expression in a sex-specific manner.

scientific article

Peptides do not prevent cleavage of endoglin to produce soluble endoglin.

scientific article published on 22 October 2014

Placental Growth Factor Is Secreted by the Human Endometrium and Has Potential Important Functions during Embryo Development and Implantation.

scientific article

Placental SEMA3B expression is not altered in severe early onset preeclampsia

scientific article published on 16 October 2014

Placental specific mRNA in the maternal circulation are globally dysregulated in pregnancies complicated by fetal growth restriction

scientific article

Placental-Specific sFLT-1 e15a Protein Is Increased in Preeclampsia, Antagonizes Vascular Endothelial Growth Factor Signaling, and Has Antiangiogenic Activity.

scientific article published on 28 September 2015

Placental-specific sFLT-1: role in pre-eclamptic pathophysiology and its translational possibilities for clinical prediction and diagnosis

scientific article

Plasma MIC-1 and PAPP-a levels are decreased among women presenting to an early pregnancy assessment unit, have fetal viability confirmed but later miscarry

scientific article

Proton Pump Inhibitors Decrease Soluble fms-Like Tyrosine Kinase-1 and Soluble Endoglin Secretion, Decrease Hypertension, and Rescue Endothelial Dysfunction

scientific article published on 23 January 2017

Reepithelialization of the uterine surface arises from endometrial glands: evidence from a functional mouse model of breakdown and repair

scientific article published on 5 May 2010

Resveratrol inhibits release of soluble fms-like tyrosine kinase (sFlt-1) and soluble endoglin and improves vascular dysfunction - implications as a preeclampsia treatment.

scientific article

Role of Label-Retaining Cells in Estrogen-Induced Endometrial Regeneration

scientific article published on 07 November 2011

Screening circulating proteins to identify biomarkers of fetal macrosomia

scientific article published on 18 September 2019

Serum concentrations of soluble Flt-1 are decreased among women with a viable fetus and no symptoms of miscarriage destined for pregnancy loss

scientific article

Sofalcone upregulates the nuclear factor (erythroid-derived 2)-like 2/heme oxygenase-1 pathway, reduces soluble fms-like tyrosine kinase-1, and quenches endothelial dysfunction: potential therapeutic for preeclampsia.

scientific article

Soluble endoglin production is upregulated by oxysterols but not quenched by pravastatin in primary placental and endothelial cells

scientific article

Stability of absolute copy number of housekeeping genes in preeclamptic and normal placentas, as measured by digital PCR.

scientific article published on 16 October 2014

Steroid sulfatase is increased in the placentas and whole blood of women with early-onset preeclampsia

scientific article published on 15 October 2016

Stimulation of epithelial repair is a likely mechanism for the action of mifepristone in reducing duration of bleeding in users of progestogen-only contraceptives

scientific article published on 22 May 2008

Sulfasalazine decreases soluble fms-like tyrosine kinase-1 secretion potentially via inhibition of upstream placental epidermal growth factor receptor signalling

scientific article published on 10 September 2019

Targeted nanoparticle delivery of doxorubicin into placental tissues to treat ectopic pregnancies.

scientific article published on 3 January 2013

The long-term actions of etonogestrel and levonorgestrel on decidualized and non-decidualized endometrium in a mouse model mimic some effects of progestogen-only contraceptives in women

scientific article published in January 2007

The untapped potential of placenta-enriched molecules for diagnostic and therapeutic development

scientific article published on 04 February 2019

Transcription factors E2F1 and E2F3 are expressed in placenta but do not regulate MMP14.

scientific article

Variable effect of maternal oral glucose load on circulating cell-free placental mRNAs.

scientific article published on 12 April 2016

Vinorelbine Potently Induces Placental Cell Death, Does Not Harm Fertility and is a Potential Treatment for Ectopic Pregnancy.

scientific article published on 2 February 2018

YC-1 reduces placental sFlt-1 and soluble endoglin production and decreases endothelial dysfunction: A possible therapeutic for preeclampsia

scientific article published on 6 July 2015

sFlt-1 and soluble endoglin concentrations in serum vs plasma in preterm preeclampsia: Are they interchangeable for biomarker studies?

scientific article

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