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List of works by Chiara Riganti

"Three-Bullets" Loaded Mesoporous Silica Nanoparticles for Combined Photo/Chemotherapy

scientific article published on 31 May 2019

6,7-Dimethoxy-2-phenethyl-1,2,3,4-tetrahydroisoquinoline amides and corresponding ester isosteres as multidrug resistance reversers

scientific article published on 01 December 2020

A LDL-masked liposomal-doxorubicin reverses drug resistance in human cancer cells

scientific article

A diabetic milieu promotes OCT4 and NANOG production in human visceral-derived adipose stem cells

scientific article published on 12 October 2012

ABCA1/ABCB1 Ratio Determines Chemo- and Immune-Sensitivity in Human Osteosarcoma

scientific article published on 06 March 2020

Aceclofenac–Galactose Conjugate: Design, Synthesis, Characterization, and Pharmacological and Toxicological Evaluations

scientific article published on 27 June 2018

Activation of nuclear factor-kappa B pathway by simvastatin and RhoA silencing increases doxorubicin cytotoxicity in human colon cancer HT29 cells

scientific article published on 7 May 2008

Antioxidants prevent the RhoA inhibition evoked by crocidolite asbestos in human mesothelial and mesothelioma cells

scientific article published on 21 January 2011

Applicability and Limitations in the Characterization of Poly-Dispersed Engineered Nanomaterials in Cell Media by Dynamic Light Scattering (DLS)

scientific article published on 22 November 2019

Artemisinin induces doxorubicin resistance in human colon cancer cells via calcium-dependent activation of HIF-1alpha and P-glycoprotein overexpression.

scientific article published on 09 March 2009

Artemisinin inhibits inducible nitric oxide synthase and nuclear factor NF-kB activation

scientific article published on September 2003

Asbestos induces doxorubicin resistance in MM98 mesothelioma cells via HIF-1alpha.

scientific article

Asbestos induces nitric oxide synthesis in mesothelioma cells via Rho signaling inhibition

scientific article published on 22 February 2007

Atorvastatin modulates anti-proliferative and pro-proliferative signals in Her2/neu-positive mammary cancer

scientific article

Carbonic Anhydrase XII Inhibitors Overcome Temozolomide Resistance in Glioblastoma

scientific article published on 10 April 2019

Classical inhibitors of NOX NAD(P)H oxidases are not specific.

scientific article published on October 2008

Coencapsulation of disulfiram and doxorubicin in liposomes strongly reverses multidrug resistance in breast cancer cells

scientific article published on 03 March 2020

Combination of PDT and NOPDT with a Tailored BODIPY Derivative

scientific article published on 07 November 2019

Consensus guidelines for the definition, detection and interpretation of immunogenic cell death

scientific article published on 01 March 2020

Consensus guidelines for the detection of immunogenic cell death

scientific article published on October 2014

Correction to: The SRCIN1/p140Cap adaptor protein negatively regulates the aggressiveness of neuroblastoma

scientific article published on 01 April 2020

Crocidolite asbestos inhibits pentose phosphate oxidative pathway and glucose 6-phosphate dehydrogenase activity in human lung epithelial cells.

scientific article published in May 2002

Cycling of NADPH by glucose 6-phosphate dehydrogenase optimizes the spectrophotometric assay of nitric oxide synthase activity in cell lysates

scientific article published on 17 February 2006

Design and synthesis of fluorescent ligands for the detection of cannabinoid type 2 receptor (CB2R)

scientific article published on 07 January 2020

Design, Biological Evaluation, and Molecular Modeling of Tetrahydroisoquinoline Derivatives: Discovery of A Potent P-Glycoprotein Ligand Overcoming Multidrug Resistance in Cancer Stem Cells

scientific article published on 09 January 2019

Design, synthesis and biological evaluation of stereo- and regioisomers of amino aryl esters as multidrug resistance (MDR) reversers

scientific article published on 30 August 2019

Different cellular responses evoked by natural and stoichiometric synthetic chrysotile asbestos

scientific article

Digoxin and ouabain increase the synthesis of cholesterol in human liver cells.

scientific article published in May 2009

Digoxin and ouabain induce P-glycoprotein by activating calmodulin kinase II and hypoxia-inducible factor-1alpha in human colon cancer cells.

scientific article published on 30 July 2009

Digoxin and ouabain induce the efflux of cholesterol via liver X receptor signalling and the synthesis of ATP in cardiomyocytes.

scientific article

Diphenyleneiodonium inhibits the cell redox metabolism and induces oxidative stress

scientific article published on 9 September 2004

Doxorubicin induces an increase of nitric oxide synthesis in rat cardiac cells that is inhibited by iron supplementation.

scientific article published on December 2002

Doxorubicin-antioxidant co-drugs

scientific article published on 8 August 2013

Dysfunctional Vγ9Vδ2 T cells are negative prognosticators and markers of dysregulated mevalonate pathway activity in chronic lymphocytic leukemia cells.

scientific article published on 29 August 2012

ERK is a Pivotal Player of Chemo-Immune-Resistance in Cancer.

scientific article published on 21 May 2019

Endoplasmic reticulum-targeting doxorubicin: a new tool effective against doxorubicin-resistant osteosarcoma

scientific article published on 14 November 2018

FAM49B, a novel regulator of mitochondrial function and integrity that suppresses tumor metastasis

scientific article published on 23 October 2017

Fluoride effects: the two faces of janus.

scientific article published on January 2010

Geranylgeraniol prevents the cytotoxic effects of mevastatin in THP-1 cells, without decreasing the beneficial effects on cholesterol synthesis

scientific article

HIF-1 activation induces doxorubicin resistance in MCF7 3-D spheroids via P-glycoprotein expression: a potential model of the chemo-resistance of invasive micropapillary carcinoma of the breast.

scientific article

High aspect ratio materials: role of surface chemistry vs. length in the historical "long and short amosite asbestos fibers".

scientific article published on October 2010

Human γδ T-cell responses in infection and immunotherapy: common mechanisms, common mediators?

scientific article published on July 2012

Hypoxia Dictates Metabolic Rewiring of Tumors: Implications for Chemoresistance

scientific article published on 04 December 2020

IDH2 inhibition enhances proteasome inhibitor responsiveness in hematological malignancies

scientific article published on 19 November 2018

IGHV unmutated CLL B cells are more prone to spontaneous apoptosis and subject to environmental prosurvival signals than mutated CLL B cells

scientific article published on 04 March 2011

Immune Modulation by Zoledronic Acid in Human Myeloma: An Advantageous Cross-Talk between V 9V 2 T Cells, CD8+ T Cells, Regulatory T Cells, and Dendritic Cells

scientific article published on 13 July 2011

Impaired chromaffin cell excitability and exocytosis in autistic Timothy syndrome TS2-neo mouse rescued by L-type calcium channel blockers

scientific article published on 28 January 2019

Inhibition of the mevalonate pathway to override chemoresistance and promote the immunogenic demise of cancer cells: Killing two birds with one stone.

scientific article published on 29 July 2013

Insights in the chemical components of liposomes responsible for P-glycoprotein inhibition

scientific article published on 10 July 2013

Insights into P-Glycoprotein Inhibitors: New Inducers of Immunogenic Cell Death

scientific article published on 22 April 2020

Iron-loaded synthetic chrysotile: a new model solid for studying the role of iron in asbestos toxicity

scientific article published on 22 February 2007

Liposome-encapsulated doxorubicin reverses drug resistance by inhibiting P-glycoprotein in human cancer cells.

scientific article published on 5 May 2011

Long and short fiber amosite asbestos alters at a different extent the redox metabolism in human lung epithelial cells

scientific article published in November 2003

MRP1-Collateral Sensitizers as a Novel Therapeutic Approach in Resistant Cancer Therapy: An In Vitro and In Vivo Study in Lung Resistant Tumor

scientific article published on 08 May 2020

Metabolic Alterations in a Slow-Paced Model of Pancreatic Cancer-Induced Wasting.

scientific article published on 26 February 2018

Methotrexate-Loaded Solid Lipid Nanoparticles: Protein Functionalization to Improve Brain Biodistribution

scientific article published on 02 February 2019

Mitochondrial-targeting nitrooxy-doxorubicin: a new approach to overcome drug resistance

scientific article published on 7 December 2012

Modulation of doxorubicin resistance by the glucose-6-phosphate dehydrogenase activity

scientific article published on October 2011

Mutant p53-Associated Molecular Mechanisms of ROS Regulation in Cancer Cells

scientific article published on 26 February 2020

NAMPT Over-Expression Recapitulates the BRAF Inhibitor Resistant Phenotype Plasticity in Melanoma

scientific article published on 20 December 2020

Na+/H+ exchanger activity is increased in doxorubicin-resistant human colon cancer cells and its modulation modifies the sensitivity of the cells to doxorubicin

scientific article

Nanoparticle- and liposome-carried drugs: new strategies for active targeting and drug delivery across blood-brain barrier.

scientific article published on July 2013

New Strategies to Overcome Resistance to Chemotherapy and Immune System in Cancer

scientific article published on 26 September 2019

New Tetrahydroisoquinoline Derivatives Overcome Pgp Activity in Brain-Blood Barrier and Glioblastoma Multiforme in Vitro

scientific article published on 09 June 2018

Nitric oxide and P-glycoprotein modulate the phagocytosis of colon cancer cells.

scientific article published on July 2011

Nitric oxide donor doxorubicins accumulate into Doxorubicin-resistant human colon cancer cells inducing cytotoxicity

scientific article published on 4 April 2011

Nitroarginine methyl ester and canavanine lower intracellular reduced glutathione.

scientific article

Omega 3 fatty acids chemosensitize multidrug resistant colon cancer cells by down-regulating cholesterol synthesis and altering detergent resistant membranes composition

scientific article published on 13 November 2013

Overcoming multidrug resistance by targeting mitochondria with NO-donating doxorubicins.

scientific article published on 14 January 2016

Paracetamol-Galactose Conjugate: A Novel Prodrug for an Old Analgesic Drug

scientific article published on 12 September 2019

Pleiotropic effects of cardioactive glycosides.

scientific article

Potential toxicity of nonregulated asbestiform minerals: balangeroite from the western Alps. Part 2: Oxidant activity of the fibers.

scientific article published on January 2005

Potential toxicity of nonregulated asbestiform minerals: balangeroite from the western Alps. Part 3: Depletion of antioxidant defenses.

scientific article published on January 2005

Pro- and anti-oxidant properties of near-infrared (NIR) light responsive carbon nanoparticles

scientific article published on 11 January 2019

Retracted: Zoledronic Acid Restores Doxorubicin Chemosensitivity and Immunogenic Cell Death in Multidrug-Resistant Human Cancer Cells

retracted article

Rictor/mTORC2 deficiency enhances keratinocyte stress tolerance via mitohormesis

scientific article

Self-assembling nanoparticles encapsulating zoledronic acid revert multidrug resistance in cancer cells

scientific article published on 9 September 2015

Simian virus 40 infection down-regulates the expression of nitric oxide synthase in human mesothelial cells

scientific article published in June 2004

Small Nucleolar RNAs Determine Resistance to Doxorubicin in Human Osteosarcoma

scientific article published on 24 June 2020

Statins revert doxorubicin resistance via nitric oxide in malignant mesothelioma.

scientific article published on July 2006

Temozolomide down-regulates P-glycoprotein in human blood-brain barrier cells by disrupting Wnt3 signaling

scientific article published on 15 June 2013

Temozolomide downregulates P-glycoprotein expression in glioblastoma stem cells by interfering with the Wnt3a/glycogen synthase-3 kinase/β-catenin pathway

scientific article published on 28 July 2013

The ATP-binding cassette transporter A1 regulates phosphoantigen release and Vγ9Vδ2 T cell activation by dendritic cells.

scientific article published on 5 June 2017

The NADPH oxidase inhibitor apocynin (acetovanillone) induces oxidative stress

scientific article published on 24 August 2005

The NADPH oxidase inhibitor apocynin induces nitric oxide synthesis via oxidative stress

scientific article published on 23 December 2007

The SRCIN1/p140Cap adaptor protein negatively regulates the aggressiveness of neuroblastoma

scientific article published on 08 July 2019

The association of statins plus LDL receptor-targeted liposome-encapsulated doxorubicin increases in vitro drug delivery across blood-brain barrier cells.

scientific article

The pentose phosphate pathway: An antioxidant defense and a crossroad in tumor cell fate ⬇️

scientific article published on May 11, 2012

Tuning the Hydrophobicity of a Mitochondria-Targeted NO Photodonor

scientific article published on 08 May 2018

Validation of Thiosemicarbazone Compounds as P-Glycoprotein Inhibitors in Human Primary Brain-Blood Barrier and Glioblastoma Stem Cells

scientific article published on 02 July 2019

Wnt/IL-1β/IL-8 autocrine circuitries control chemoresistance in mesothelioma initiating cells by inducing ABCB5

scientific article published on 04 June 2019

Zoledronic acid potentiates mTOR inhibition and abolishes the resistance of osteosarcoma cells to RAD001 (Everolimus): pivotal role of the prenylation process.

scientific article published on 22 October 2010

Zoledronic acid repolarizes tumour-associated macrophages and inhibits mammary carcinogenesis by targeting the mevalonate pathway.

scientific article published on December 2010

Zoledronic acid-encapsulating self-assembling nanoparticles and doxorubicin: a combinatorial approach to overcome simultaneously chemoresistance and immunoresistance in breast tumors

scientific article published on 09 March 2016

iNOS activity is necessary for the cytotoxic and immunogenic effects of doxorubicin in human colon cancer cells.

scientific article

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