List of works by Martin Michaelis

A new strategy in the treatment of chemoresistant lung adenocarcinoma via specific siRNA transfection of SRF, E2F1, Survivin, HIF and STAT3.

scientific article published on 13 March 2014

A novel immunomodulatory mechanism of ribavirin in suppressing natural killer cell function

scientific article published on 7 August 2009

A systems pharmacology approach to improve drug therapy in NSCLC: establishing a CESAR network.

scientific article published on January 2014

ABCB1 as predominant resistance mechanism in cells with acquired SNS-032 resistance

scientific article published on 9 August 2016

ABCG2 impairs the activity of the aurora kinase inhibitor tozasertib but not of alisertib

scientific article published on 28 September 2015

Acquired resistance to oxaliplatin is not directly associated with increased resistance to DNA damage in SK-N-ASrOXALI4000, a newly established oxaliplatin-resistant sub-line of the neuroblastoma cell line SK-N-AS

scientific article

Activation of telomerase in glioma cells by human cytomegalovirus: another piece of the puzzle.

scientific article published on 24 March 2009

Adaptation of cancer cells from different entities to the MDM2 inhibitor nutlin-3 results in the emergence of p53-mutated multi-drug-resistant cancer cells.

scientific article published on 15 December 2011

Alterations of the gene expression profile in renal cell carcinoma after treatment with the histone deacetylase-inhibitor valproic acid and interferon-alpha

scientific article published on 17 July 2010

An endogenous inhibitor of angiogenesis derived from a transitional cell carcinoma: clipped beta2-glycoprotein-I.

scientific article published on 7 September 2006

Anti-cancer effects of artesunate in a panel of chemoresistant neuroblastoma cell lines

scientific article

Anti-cancer effects of bortezomib against chemoresistant neuroblastoma cell lines in vitro and in vivo.

scientific article published on February 2006

Anticancer effects of the nitric oxide-modified saquinavir derivative saquinavir-NO against multidrug-resistant cancer cells

scientific article

Antitumor activity of the selective MDM2 antagonist nutlin-3 against chemoresistant neuroblastoma with wild-type p53.

scientific article

Antiviral activity of glycyrrhizic acid derivatives against SARS-coronavirus

scientific article published in February 2005

Antiviral and immunomodulatory activity of the metal chelator ethylenediaminedisuccinic acid against cytomegalovirus in vitro and in vivo

scientific article published on July 2002

Aprotinin Inhibits SARS-CoV-2 Replication

scientific article published on 30 October 2020

Artesunate Impairs Growth in Cisplatin-Resistant Bladder Cancer Cells by Cell Cycle Arrest, Apoptosis and Autophagy Induction

scientific article published on 09 December 2020

Association between acquired resistance to PLX4032 (vemurafenib) and ATP-binding cassette transporter expression

scientific article

Aurora kinases as targets in drug-resistant neuroblastoma cells

scientific article

Botanical drugs and supplements affecting the immune response in the time of COVID-19: Implications for research and clinical practice

scientific article published on 29 December 2020

Bovine seminal ribonuclease attached to nanoparticles made of polylactic acid kills leukemia and lymphoma cell lines in vitro

scientific article published in June 2000

COVID-19-Related Coagulopathy-Is Transferrin a Missing Link?

scientific article published on 30 July 2020

Changes associated with Ebola virus adaptation to novel species

scientific article

Characterization of drug-resistant neuroblastoma cell lines by comparative genomic hybridization.

scientific article published on January 2005

Checkpoint kinase inhibitor AZD7762 strongly sensitises urothelial carcinoma cells to gemcitabine

scientific article published on 03 January 2017

Chemoresistance acquisition induces a global shift of expression of aniogenesis-associated genes and increased pro-angogenic activity in neuroblastoma cells

scientific article published on 29 September 2009

Chemoresistance induces enhanced adhesion and transendothelial penetration of neuroblastoma cells by down-regulating NCAM surface expression

scientific article

Chemoresistance is associated with increased cytoprotective autophagy and diminished apoptosis in bladder cancer cells treated with the BH3 mimetic (-)-Gossypol (AT-101)

scientific article published on 7 April 2015

Cisplatin-resistant neuroblastoma cells express enhanced levels of epidermal growth factor receptor (EGFR) and are sensitive to treatment with EGFR-specific toxins

scientific article

Comparison of cytokine levels from undiluted vitreous of untreated patients with retinal vein occlusion

scientific article published on 08 November 2011

Comparison of pro-inflammatory cytokine expression and cellular signal transduction in human macrophages infected with different influenza A viruses ⬇️

scientific article published on September 24, 2010

Computational analysis of Ebolavirus data: prospects, promises and challenges

scientific article

Conserved differences in protein sequence determine the human pathogenicity of Ebolaviruses.

scientific article published on 24 March 2016

Correlation of inflammatory and proangiogenic cytokines from undiluted vitreous samples with spectral domain OCT scans, in untreated branch retinal vein occlusion

scientific article published on 4 June 2013

Corrigendum: SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia

article

Coupling of the antitumoral enzyme bovine seminal ribonuclease to polyethylene glycol chains increases its systemic efficacy in mice

scientific article published on 01 February 2002

Cytomegalovirus infection blocks apoptosis in cancer cells.

scientific article published on June 2004

Cytotoxicity of L-cycloserine against human neuroblastoma and medulloblastoma cells is associated with the suppression of ganglioside expression.

scientific article published in November 1999

Cytotoxicity of aphidicolin and its derivatives against neuroblastoma cells in vitro: synergism with doxorubicin and vincristine

scientific article published on July 2000

Dasatinib enhances tumor growth in gemcitabine-resistant orthotopic bladder cancer xenografts

scientific article

Design and synthesis of dipeptidyl glutaminyl fluoromethyl ketones as potent severe acute respiratory syndrome coronovirus (SARS-CoV) inhibitors

scientific article published in February 2006

Development of antiviral therapy for severe acute respiratory syndrome.

scientific article

Differential antiviral and anti-inflammatory mechanisms of the flavonoids biochanin A and baicalein in H5N1 influenza A virus-infected cells

scientific article published on 23 October 2012

Differential effects of the oncogenic BRAF inhibitor PLX4032 (vemurafenib) and its progenitor PLX4720 on ABCB1 function.

scientific article published on January 2014

Discovery of epi-Enprioline as a Novel Drug for the Treatment of Vincristine Resistant Neuroblastoma

scientific article published on 08 September 2020

Doxorubicin-induced cell death requires cathepsin B in HeLa cells

scientific article published on 13 August 2010

Doxorubicin-loaded human serum albumin nanoparticles overcome transporter-mediated drug resistance in drug-adapted cancer cells

scientific article published on 14 August 2019

Drug-Resistant Urothelial Cancer Cell Lines Display Diverse Sensitivity Profiles to Potential Second-Line Therapeutics.

scientific article published on June 2015

Effects of YM155 on survivin levels and viability in neuroblastoma cells with acquired drug resistance

scientific article published on 13 October 2016

Effects of flavonoid-induced oxidative stress on anti-H5N1 influenza a virus activity exerted by baicalein and biochanin A.

scientific article

Enhanced drug targeting by attachment of an anti alphav integrin antibody to doxorubicin loaded human serum albumin nanoparticles

scientific article

Environmental conditions shape the nature of a minimal bacterial genome

scientific article published on 15 July 2019

Enzastaurin inhibits ABCB1-mediated drug efflux independently of effects on protein kinase C signalling and the cellular p53 status

scientific article

Evolving anticancer drug valproic acid: insights into the mechanism and clinical studies.

scientific article

Gene Expression Signature of Acquired Chemoresistance in Neuroblastoma Cells

scientific article published on 16 September 2020

Glycyrrhizin exerts antioxidative effects in H5N1 influenza A virus-infected cells and inhibits virus replication and pro-inflammatory gene expression

scientific article published in 2011

Glycyrrhizin inhibits highly pathogenic H5N1 influenza A virus-induced pro-inflammatory cytokine and chemokine expression in human macrophages

scientific article published on 13 April 2010

High-dose hydrocortisone reduces expression of the pro-inflammatory chemokines CXCL8 and CXCL10 in SARS coronavirus-infected intestinal cells

scientific article

Histone deacetylase inhibitors suppress natural killer cell cytolytic activity

scientific article

Human cytomegalovirus infection alters PC3 prostate carcinoma cell adhesion to endothelial cells and extracellular matrix

scientific article published on October 2006

Human cytomegalovirus infection in tumor cells of the nervous system is not detectable with standardized pathologico-virological diagnostics.

scientific article

Human neuroblastoma cells with acquired resistance to the p53 activator RITA retain functional p53 and sensitivity to other p53 activating agents.

scientific article

Identification of flubendazole as potential anti-neuroblastoma compound in a large cell line screen

scientific article

In vitro antiviral activity of aphidicolin and its derivates. Synergistic effects of aphidicolin with other antiviral drugs

scientific article published in January 2002

Incorporation of doxorubicin in different polymer nanoparticles and their anticancer activity

scientific article published on 29 October 2019

Increased human cytomegalovirus replication in fibroblasts after treatment with therapeutical plasma concentrations of valproic acid

scientific article published in August 2004

Increased malignant behavior in neuroblastoma cells with acquired multi-drug resistance does not depend on P-gp expression.

scientific article published on October 2005

Increased replication of human cytomegalovirus in retinal pigment epithelial cells by valproic acid depends on histone deacetylase inhibition.

scientific article published in September 2005

Increased systemic efficacy of aphidicolin encapsulated in liposomes.

scientific article published in January 2005

Infection of cultured intestinal epithelial cells with severe acute respiratory syndrome coronavirus

scientific article published in August 2004

Infection of human retinal pigment epithelial cells with influenza A viruses.

scientific article published on 24 June 2009

Intact-Cell MALDI-ToF Mass Spectrometry for the Authentication of Drug-Adapted Cancer Cell Lines

scientific article published on 02 October 2019

Interaction of folate-conjugated human serum albumin (HSA) nanoparticles with tumour cells.

scientific article

Investigation of the influence of EPs® 7630, a herbal drug preparation from Pelargonium sidoides, on replication of a broad panel of respiratory viruses

scientific article published on 30 October 2010

Karanjin interferes with ABCB1, ABCC1, and ABCG2.

scientific article published on January 2014

Knowledge-based approach to identify key determinants of cisplatin sensitivity

scientific article published in August 2017

Measurement of cytotoxic T lymphocyte activity of human cytomegalovirus seropositive individuals by a highly sensitive coupled luminescent method

scientific article published on 8 October 2009

Minocycline inhibits West Nile virus replication and apoptosis in human neuronal cells

scientific article

Miyabeacin: A new cyclodimer presents a potential role for willow in cancer therapy

scientific article published on 15 April 2020

Multimutated herpes simplex virus g207 is a potent inhibitor of angiogenesis.

scientific article

Myrtucommulone from Myrtus communis induces apoptosis in cancer cells via the mitochondrial pathway involving caspase-9.

scientific article published on January 2008

N-acetyl-L-cysteine (NAC) inhibits virus replication and expression of pro-inflammatory molecules in A549 cells infected with highly pathogenic H5N1 influenza A virus.

scientific article

NK sensitivity of neuroblastoma cells determined by a highly sensitive coupled luminescent method

scientific article published on 14 November 2005

NSCLC cells adapted to EGFR inhibition accumulate EGFR interacting proteins and down-regulate microRNA related to epithelial-mesenchymal transition

scientific article published on January 2014

Non-Phosphorylatable PEA-15 Sensitises SKOV-3 Ovarian Cancer Cells to Cisplatin

scientific article published on 24 February 2020

Novel valproic acid derivatives with potent differentiation-inducing activity in myeloid leukemia cells

scientific article published on 28 February 2006

Of chickens and men: avian influenza in humans.

scientific article

Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2

scientific article published on 03 December 2019

Oncolytic effects of a novel influenza A virus expressing interleukin-15 from the NS reading frame

scientific article

Oncomodulation by human cytomegalovirus: evidence becomes stronger.

scientific article published on 07 February 2009

Oncomodulation by human cytomegalovirus: novel clinical findings open new roads

scientific article

Onconase induces caspase-independent cell death in chemoresistant neuroblastoma cells

scientific article

Overexpression of Midkine in malignant peripheral nerve sheath tumor cells inhibits apoptosis and increases angiogenic potency.

scientific article published on November 2005

Pharmacological activity of DTPA linked to protein-based drug carrier systems.

scientific article

Potent oncolytic activity of multimutated herpes simplex virus G207 in combination with vincristine against human rhabdomyosarcoma.

scientific article published in April 2003

Preparation, characterisation and maintenance of drug efficacy of doxorubicin-loaded human serum albumin (HSA) nanoparticles.

scientific article published on 30 March 2007

Relevance of subcellular localization of extracellular signal-regulated kinase 1/2 (ERK1/2) for cisplatin resistance.

scientific article published on 7 August 2015

Resistance acquisition to MDM2 inhibitors.

scientific article

Resistance to cytarabine induces the up-regulation of NKG2D ligands and enhances natural killer cell lysis of leukemic cells

scientific article

Resistance to nanoparticle albumin-bound paclitaxel is mediated by ABCB1 in urothelial cancer cells

scientific article

Reversal of P-glycoprotein-mediated multidrug resistance by the murine double minute 2 antagonist nutlin-3.

scientific article

Ribavirin and interferon-beta synergistically inhibit SARS-associated coronavirus replication in animal and human cell lines.

scientific article

Ribavirin inhibits angiogenesis by tetrahydrobiopterin depletion

scientific article published on 29 November 2006

Risks Posed by Reston, the Forgotten Ebolavirus

scientific article

Role of interferons in the treatment of severe acute respiratory syndrome

scientific article published on June 2004

SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia.

scientific article

SAMHD1 is a key regulator of the lineage-specific response of acute lymphoblastic leukaemias to nelarabine

scientific article published on 24 June 2020

SARS-CoV-2 and SARS-CoV differ in their cell tropism and drug sensitivity profiles

scientific article published on 06 April 2020

Selection of a highly invasive neuroblastoma cell population through long-term human cytomegalovirus infection

scientific article

Selection of proangiogenic ascorbate derivatives and their exploitation in a novel drug-releasing system for wound healing.

scientific article published in September 2011

Selective inactivation of hypomethylating agents by SAMHD1 provides a rationale for therapeutic stratification in AML

scientific article published on 02 August 2019

Simple and efficient method for the detection of diethylenetriaminepentaacetic acid

scientific article published on 01 December 1999

Structure-activity relationships of novel heteroaryl-acrylonitriles as cytotoxic and antibacterial agents.

scientific article published on 5 December 2007

Substrate-specific effects of pirinixic acid derivatives on ABCB1-mediated drug transport

scientific article published on 12 February 2016

Synthetic lethal hubs associated with vincristine resistant neuroblastoma

scientific article published on 28 October 2010

Testing of SNS-032 in a Panel of Human Neuroblastoma Cell Lines with Acquired Resistance to a Broad Range of Drugs

scientific article published on December 2013

Testing of the Survivin Suppressant YM155 in a Large Panel of Drug-Resistant Neuroblastoma Cell Lines

scientific article published on 02 March 2020

The Thrombopoietin Receptor Agonist Eltrombopag Inhibits Human Cytomegalovirus Replication Via Iron Chelation

scientific article published on 20 December 2019

The anti-tumoral drug enzastaurin inhibits natural killer cell cytotoxicity via activation of glycogen synthase kinase-3β.

scientific article published on 8 October 2010

The multi-targeted kinase inhibitor sorafenib inhibits human cytomegalovirus replication.

scientific article

The small molecule inhibitor YK-4-279 disrupts mitotic progression of neuroblastoma cells, overcomes drug resistance and synergizes with inhibitors of mitosis

scientific article

The story of human cytomegalovirus and cancer: increasing evidence and open questions

scientific article published on January 2009

The threat of avian influenza A (H5N1). Part I: Epidemiologic concerns and virulence determinants.

scientific article

The threat of avian influenza A (H5N1). Part III: Antiviral therapy.

scientific article published on 12 April 2007

The threat of avian influenza A (H5N1). Part IV: Development of vaccines.

scientific article published on June 2007

The threat of avian influenza a (H5N1): part II: Clues to pathogenicity and pathology.

scientific article published on 4 April 2007

Thiourea and Guanidine Compounds and Their Iridium Complexes in Drug-Resistant Cancer Cell Lines: Structure-Activity Relationships and Direct Luminescent Imaging

scientific article published on 20 December 2019

Toona sinensis Roem tender leaf extract inhibits SARS coronavirus replication

scientific article

Towards an unbiased, collaborative effort to reach evidence about the presence of human cytomegalovirus in glioblastoma (and other tumors).

scientific article published in July 2015

Treatment of drug-resistant human neuroblastoma cells with cyclodextrin inclusion complexes of aphidicolin

scientific article published in June 2001

Treatment of glioblastoma with poly(isohexyl cyanoacrylate) nanoparticles

scientific article published on 27 May 2011

Tumor cells infected with oncolytic influenza A virus prime natural killer cells for lysis of resistant tumor cells

scientific article

Utilising the EGFR interactome to identify mechanisms of drug resistance in non-small cell lung cancer - Proof of concept towards a systems pharmacology approach

scientific article published on 22 April 2016

Valproate and valproate-analogues: potent tools to fight against cancer.

scientific article

Valproic acid and interferon-alpha synergistically inhibit neuroblastoma cell growth in vitro and in vivo

scientific article published in December 2004

Valproic acid as anti-cancer drug.

scientific article published on January 2007

Valproic acid inhibits adhesion of vincristine- and cisplatin-resistant neuroblastoma tumour cells to endothelium

scientific article published on 15 May 2007

Valproic acid interferes with antiviral treatment in human cytomegalovirus-infected endothelial cells

scientific article published on 12 November 2007

West Nile virus infection induces interferon signalling in human retinal pigment epithelial cells

scientific article published in February 2006

[Seasonal pathogen epidemics and global pandemics. Influenza virus: biology and pathogenicity]

scientific article published on 01 March 2011

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