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List of works by Sakae Tanaka

2-Methacryloyloxyethyl Phosphorylcholine Polymer Coating Inhibits Bacterial Adhesion and Biofilm Formation on a Suture: An In Vitro and In Vivo Study

scientific article published on 01 October 2020

A New Mechanism of Bone Destruction in Rheumatoid Arthritis: Synovial Fibroblasts Induce Osteoclastogenesis ⬇️

scientific article published on November 17, 1997

A hydrated phospholipid polymer-grafted layer prevents lipid-related oxidative degradation of cross-linked polyethylene

scientific article published on 11 October 2016

A modified technique to reduce tibial keel cutting errors during an Oxford unicompartmental knee arthroplasty

scientific article

A novel function of RING finger protein 10 in transcriptional regulation of the myelin-associated glycoprotein gene and myelin formation in Schwann cells

scientific journal article

A population approach to analyze the effectiveness of a back extension exercise "One Stretch" in patients with low back pain: A replication study

scientific article published on 02 April 2016

A possible mechanism of the specific action of bisphosphonates on osteoclasts: tiludronate preferentially affects polarized osteoclasts having ruffled borders

scientific article published on August 1995

A review of denosumab for the treatment of osteoporosis

scientific article

A sliding scale to predict postoperative complications undergoing posterior spine surgery

scientific article published on 05 July 2019

Accumulation of metabolic risk factors such as overweight, hypertension, dyslipidaemia, and impaired glucose tolerance raises the risk of occurrence and progression of knee osteoarthritis: a 3-year follow-up of the ROAD study

scientific article published on 14 July 2012

Activation of ERK or inhibition of JNK ameliorates H(2)O(2) cytotoxicity in mouse renal proximal tubule cells

scientific article published on April 2004

Adamts17 is involved in skeletogenesis through modulation of BMP-Smad1/5/8 pathway

scientific article published on 14 June 2019

Adenovirus-mediated overexpression of C-terminal Src kinase (Csk) in type I astrocytes interferes with cell spreading and attachment to fibronectin. Correlation with tyrosine phosphorylations of paxillin and FAK.

scientific article published in January 1999

Akt protein kinase inhibits non-apoptotic programmed cell death induced by ceramide

scientific article published on 12 November 2001

Akt1 in osteoblasts and osteoclasts controls bone remodeling

scientific article

An additional reference axis improves femoral rotation alignment in image-free computer navigation assisted total knee arthroplasty

scientific article

Analysis of the affected joints in rheumatoid arthritis patients in a large Japanese cohort

scientific article published on 31 March 2012

Anterior Impingement Syndrome of the Ankle Caused by Osteoid Osteoma in the Talar Neck Treated with Arthroscopy and 3D C-Arm-Based Imaging

scientific article published on 28 March 2017

Anti-apoptotic Bcl-2 family member Mcl-1 regulates cell viability and bone-resorbing activity of osteoclasts

scientific article published on 2 October 2013

Anti-apoptotic molecule Bcl-2 regulates the differentiation, activation, and survival of both osteoblasts and osteoclasts

scientific article published on 21 October 2009

Antiapoptotic molecule Bcl-2 is essential for the anabolic activity of parathyroid hormone in bone

scientific article

Are bone and serum cefazolin concentrations adequate for antimicrobial prophylaxis?

scientific article published on 4 October 2011

Association Between Normothermia at the End of Surgery and Postoperative Complications Following Orthopedic Surgery

scientific article published on 01 January 2020

Association between dementia and postoperative complications after hip fracture surgery in the elderly: analysis of 87,654 patients using a national administrative database

scientific article published on September 2015

Association between new indices in the locomotive syndrome risk test and decline in mobility: third survey of the ROAD study

scientific article

Association of Lumbar Spondylolisthesis With Low Back Pain and Symptomatic Lumbar Spinal Stenosis in a Population-based Cohort: The Wakayama Spine Study.

scientific article

Association of dietary intake with joint space narrowing and osteophytosis at the knee in Japanese men and women: the ROAD study

scientific article

Association of dietary intake with joint space narrowing and osteophytosis at the knee in Japanese men and women: the ROAD study

Association of knee osteoarthritis with onset and resolution of pain and physical functional disability: the ROAD study

scientific article

Association of physical activities of daily living with the incidence of certified need of care in the long-term care insurance system of Japan: the ROAD study

scientific article published on 8 February 2014

Association of sustained ERK activity with integrin beta3 induction during receptor activator of nuclear factor kappaB ligand (RANKL)-directed osteoclast differentiation

scientific article published on October 2003

Associations between neck and shoulder discomfort (Katakori) and job demand, job control, and worksite support

scientific article published on 22 January 2013

Bicruciate-stabilised total knee arthroplasty provides good functional stability during high-flexion weight-bearing activities

scientific article published on 10 April 2019

Bilateral Stress Fractures of the Talus Associated with Adult-Acquired Flatfoot Deformities

scientific article published on 09 September 2018

Bim: Guardian of Tissue Homeostasis and Critical Regulator of the Immune System, Tumorigenesis and Bone Biology ⬇️

scientific article published on 03 June 2011

Biphasic regulation of chondrocytes by Rela through induction of anti-apoptotic and catabolic target genes

scientific article published on 10 November 2016

Bone resorption is regulated by cell-autonomous negative feedback loop of Stat5-Dusp axis in the osteoclast.

scientific article published on 23 December 2013

Brain-type creatine kinase has a crucial role in osteoclast-mediated bone resorption

scientific article published in September 2008

C7 sagittal vertical axis is the determinant of the C5-C7 angle in cervical sagittal alignment

scientific article published on 15 November 2016

CTLA4-Ig Directly Inhibits Osteoclastogenesis by Interfering With Intracellular Calcium Oscillations in Bone Marrow Macrophages

scientific article published on 16 July 2019

Capturing microscopic features of bone remodeling into a macroscopic model based on biological rationales of bone adaptation

scientific article published on 18 May 2017

Cervical Anterolisthesis: A Predictor of Poor Neurological Outcomes in Cervical Spondylotic Myelopathy Patients After Cervical Laminoplasty

scientific article published on April 2016

Cervical canal stenosis caused by progressive fusion and enlargement of cervical vertebrae with features of Proteus syndrome and Klippel-Feil syndrome

scientific article published on 13 June 2013

Cervical microendoscopic interlaminar decompression through a midline approach in patients with cervical myelopathy: a technical note

scientific article

Class IA phosphatidylinositol 3-kinase regulates osteoclastic bone resorption through protein kinase B-mediated vesicle transport.

scientific article

Classification of High Intensity Zones of the Lumbar Spine and Their Association with Other Spinal MRI Phenotypes: The Wakayama Spine Study.

scientific article

Clinical characteristics of rheumatoid arthritis patients undergoing cervical spine surgery: an analysis of National Database of Rheumatic Diseases in Japan

scientific article

Clinical outcome of anatomic double-bundle ACL reconstruction and 3D CT model-based validation of femoral socket aperture position

scientific article published on 2 October 2013

Comparison of mouse and human ankles and establishment of mouse ankle osteoarthritis models by surgically-induced instability.

scientific article

Comparison of the Japanese Orthopaedic Association (JOA) score and modified JOA (mJOA) score for the assessment of cervical myelopathy: a multicenter observational study

scientific article published on 2 April 2015

Complications and Postoperative Mortality Rate After Surgery for Pathological Femur Fracture Related to Bone Metastasis: Analysis of a Nationwide Database.

scientific article published on 5 October 2015

Complications of implant removal in ankle fractures

scientific article published on 28 February 2019

Comprehensive assay for the molecular profiling of cancer by target enrichment from formalin-fixed paraffin-embedded specimens

scientific article published on 05 March 2019

Concurrent spinal schwannoma and meningioma mimicking a single cervical dumbbell-shaped tumor: case report

scientific article published on 28 August 2015

Correction to: RANKL as a therapeutic target of rheumatoid arthritis

scientific article published on 17 December 2020

Determination of differential gene expression profiles in superficial and deeper zones of mature rat articular cartilage using RNA sequencing of laser microdissected tissue specimens.

scientific article

Development of femoral bone fracture model simulating muscular contraction force by pneumatic rubber actuator

scientific article published on January 2014

Development of nomograms for prognostication of patients with primary soft tissue sarcomas of the trunk and extremity: report from the Bone and Soft Tissue Tumor Registry in Japan

scientific article published on 04 July 2019

Diagnosing Discogenic Low Back Pain Associated with Degenerative Disc Disease Using a Medical Interview

scientific article

Different regulation of limb development by p63 transcript variants

scientific article

Disappearance of lung adenocarcinoma after total en bloc spondylectomy using frozen tumor-bearing vertebra for reconstruction

scientific article

Disease activity affects the recurrent deformities of the lesser toes after resection arthroplasty for rheumatoid forefoot deformity

scientific article published on 17 June 2020

Distinct roles of Smad pathways and p38 pathways in cartilage-specific gene expression in synovial fibroblasts

scientific article published on March 2004

Distinguishing the proapoptotic and antiresorptive functions of risedronate in murine osteoclasts: role of the Akt pathway and the ERK/Bim axis.

scientific article published in December 2011

Dnmt3a Regulates Proliferation of Muscle Satellite Cells via p57Kip2.

scientific article

Does mild cognitive impairment affect the occurrence of radiographic knee osteoarthritis? A 3-year follow-up in the ROAD study.

scientific article

Does osteophytosis at the knee predict health-related quality of life decline? A 3-year follow-up of the ROAD study

scientific article published on 30 May 2014

Does the microendoscopic technique reduce mortality and major complications in patients undergoing lumbar discectomy? A propensity score-matched analysis using a nationwide administrative database

scientific article published on February 2016

Eccentric femoral tunnel widening in anatomic anterior cruciate ligament reconstruction

scientific article published on 27 March 2014

Economic Impact of Venous Thromboembolism Following Major Orthopaedic Surgery in Japan

scientific article published on 27 February 2013

Ectodomain shedding of receptor activator of NF-kappaB ligand.

scientific article published on January 2007

Effect of Preoperative Sagittal Balance on Cervical Laminoplasty Outcomes

scientific article

Effects of Surface Modification and Bulk Geometry on the Biotribological Behavior of Cross-Linked Polyethylene: Wear Testing and Finite Element Analysis

scientific article published on 25 October 2015

Effects of extra irradiation on surface and bulk properties of PMPC-grafted cross-linked polyethylene

scientific article published on 16 July 2015

Effects of fondaparinux on pulmonary embolism following hemiarthroplasty for femoral neck fracture: a retrospective observational study using the Japanese Diagnosis Procedure Combination database

scientific article published on 18 July 2014

Elevated levels of phosphorylated neurofilament heavy subunit in the cerebrospinal fluid of patients with lumbar spinal stenosis: preliminary findings

scientific article published on 20 March 2015

Epidemiology of the locomotive syndrome: The research on osteoarthritis/osteoporosis against disability study 2005-2015.

scientific article

Epigenetic regulation of osteoclast differentiation.

scientific article published on December 2011

Epigenetic regulation of osteoclast differentiation: possible involvement of Jmjd3 in the histone demethylation of Nfatc1.

scientific article published in November 2011

Erk pathways negatively regulate matrix mineralization

scientific article published on 15 September 2006

Erratum to: Association between new indices in the locomotive syndrome risk test and decline in mobility: third survey of the ROAD study

scientific article published on 26 August 2015

Essential role of synoviolin in embryogenesis

scientific journal article

Estimated risk for chronic pain determined using the generic STarT Back 5-item screening tool

scientific article

Evaluation of Comorbidity Indices for a Study of Patient Outcomes Following Cervical Decompression Surgery: A Retrospective Cohort Study.

scientific article

Excessive mechanical loading promotes osteoarthritis through the gremlin-1-NF-κB pathway

scientific article published on 29 March 2019

Exercise habits during middle age are associated with lower prevalence of sarcopenia: the ROAD study

scientific article published on 22 October 2013

Extensive ossification of the paraspinal ligaments in a patient with vitamin D-resistant rickets: Case report with literature review

scientific article published on 28 August 2016

Factors affecting bone union after distal shortening oblique osteotomy of the lesser metatarsals

scientific article published on 24 June 2019

Factors affecting changes in the serum levels of 25-hydroxyvitamin D: a 3-year follow-up of the ROAD study

scientific article published on 19 June 2015

Factors related to the quality of life in patients with bone metastases

scientific article published on 18 July 2019

Fcgamma receptor signaling in primary human microglia: differential roles of PI-3K and Ras/ERK MAPK pathways in phagocytosis and chemokine induction

scientific article published on 24 February 2004

Fungal arthritis of the wrist caused by Candida parapsilosis during infliximab therapy for rheumatoid arthritis

scientific article published on 15 February 2012

Generation of Col2a1-EGFP iPS cells for monitoring chondrogenic differentiation

scientific article

Genomewide comprehensive analysis reveals critical cooperation between Smad and c-Fos in RANKL-induced osteoclastogenesis

scientific article published in May 2015

Global epigenomic analysis indicates protocadherin-7 activates osteoclastogenesis by promoting cell-cell fusion

scientific article published on 13 November 2014

Gorham-Stout Syndrome of the Shoulder Girdle Successfully Controlled by Antiresorptive Agents: A Report of 2 Cases

scientific article published on 01 April 2019

Hes1 functions downstream of growth factors to maintain oligodendrocyte lineage cells in the early progenitor stage.

scientific article published on 15 December 2010

Heterotopic Ossification of the Peroneus Longus Tendon in the Retromalleolar Portion with the Peroneus Quartus Muscle: A Case Report

scientific article published on 29 July 2018

Hypermobile Medial Meniscus: A Case Report

scientific article published on 01 July 2019

Hyperphosphorylated neurofilament NF-H as a biomarker of the efficacy of minocycline therapy for spinal cord injury

scientific article published on 31 August 2010

Hypoglossal Nerve Palsy as a Cause of Severe Dysphagia along with the Oropharyngeal Stenosis due to Occipitocervical Kyphosis

scientific article published on 06 March 2019

Identification of Nedd9 as a TGF-β-Smad2/3 Target Gene Involved in RANKL-Induced Osteoclastogenesis by Comprehensive Analysis.

scientific article

Identification of SCAN domain zinc-finger gene ZNF449 as a novel factor of chondrogenesis

scientific article

Identification of an alternatively spliced variant of Ca2+-promoted Ras inactivator as a possible regulator of RANKL shedding

scientific article

Iliotibial band irritation caused by the EndoButton after anatomic double-bundle anterior cruciate ligament reconstruction: report of two cases

scientific article published on 25 April 2013

Impact of age and comorbidity burden on mortality and major complications in older adults undergoing orthopaedic surgery: an analysis using the Japanese diagnosis procedure combination database.

scientific article

Impact of biologics on the prevalence of orthopedic surgery in the National Database of Rheumatic Diseases in Japan

scientific article published on 8 January 2010

Impact of hospital volume on postoperative complications and in-hospital mortality after musculoskeletal tumor surgery: analysis of a national administrative database

scientific article published in September 2013

Impingement of the Mobile Bearing on the Lateral Wall of the Tibial Tray in Unicompartmental Knee Arthroplasty

scientific article published on 27 February 2016

In vitro and in vivo assays for osteoclast apoptosis

scientific article

Incidence of certified need of care in the long-term care insurance system and its risk factors in the elderly of Japanese population-based cohorts: the ROAD study

scientific article published on 11 September 2013

Individual and combining effects of anti-RANKL monoclonal antibody and teriparatide in ovariectomized mice

scientific article published on 21 January 2015

Influence of incidental dural tears and their primary microendoscopic repairs on surgical outcomes in patients undergoing microendoscopic lumbar surgery

scientific article published on 19 April 2019

Influence of navigation system updates on total knee arthroplasty

scientific article

Influences of dehydration and rehydration on the lubrication properties of phospholipid polymer-grafted cross-linked polyethylene

scientific article published on 2 June 2015

Integrin alpha4beta1 promotes focal adhesion kinase-independent cell motility via alpha4 cytoplasmic domain-specific activation of c-Src.

scientific article

Interdigital Neuroma in the Second Intermetatarsal Space Associated with Metatarsophalangeal Joint Instability.

scientific article published on 24 November 2016

Intra-articular injection of hyaluronan restores the aberrant expression of matrix metalloproteinase-13 in osteoarthritic subchondral bone.

scientific article

Intracellular and extracellular ATP coordinately regulate the inverse correlation between osteoclast survival and bone resorption

scientific article

Intracellular signal transduction pathways: good therapeutic targets for joint destruction in rheumatoid arthritis

scientific article published on 01 January 2005

Intraoperative Tibial Anteroposterior Axis Could Not Be Replicated After Tibial Osteotomy in Total Knee Arthroplasty

scientific article published on 07 June 2019

Intrathecal injection of a therapeutic gene-containing polyplex to treat spinal cord injury

scientific article

Involvement of a disintegrin and metalloproteinase 10 and 17 in shedding of tumor necrosis factor-alpha

scientific article published on August 2009

Involvement of receptor activator of nuclear factor kappaB ligand/osteoclast differentiation factor in osteoclastogenesis from synoviocytes in rheumatoid arthritis

scientific article published on 01 February 2000

Is osteoporosis a predictor for future sarcopenia or vice versa? Four-year observations between the second and third ROAD study surveys

scientific article published on 24 November 2016

Ischemic stroke after cervical spine injury: analysis of 11,005 patients using the Japanese Diagnosis Procedure Combination database

scientific article

Joint space narrowing, body mass index, and knee pain: the ROAD study (OAC1839R1).

scientific article

Jun Dimerization Protein 2 (JDP2), a Member of the AP-1 Family of Transcription Factor, Mediates Osteoclast Differentiation Induced by RANKL ⬇️

scientific article published on April 21, 2003

Lipopolysaccharide preconditioning facilitates M2 activation of resident microglia after spinal cord injury.

scientific article published on 10 July 2014

Long-Term Outcomes of Cervical Laminoplasty in the Elderly

scientific article published on 25 October 2015

Long-term safety and effectiveness of denosumab in Japanese patients with osteoporosis: 3-year post-marketing surveillance study

scientific article published on 02 January 2021

Lysophosphatidic acids and their substrate lysophospholipids in cerebrospinal fluid as objective biomarkers for evaluating the severity of lumbar spinal stenosis

scientific article published on 24 June 2019

MKK6-p38 MAPK signaling pathway enhances survival but not bone-resorbing activity of osteoclasts

scientific article published on 5 November 2007

Macrophage colon-stimulating factor (M-CSF) is essential for differentiation rather than proliferation of osteoclast progenitors

scientific article published on 01 January 1993

Macrophage migration inhibitory factor up-regulates matrix metalloproteinase-9 and -13 in rat osteoblasts. Relevance to intracellular signaling pathways

scientific article

Massively parallel sequencing of tenosynovial giant cell tumors reveals novel CSF1 fusion transcripts and novel somatic CBL mutations

scientific article published on 31 May 2019

Mechanical regulation of bone homeostasis through p130Cas-mediated alleviation of NF-κB activity

scientific article published on 25 September 2019

Mental State Can Influence the Degree of Postoperative Axial Neck Pain Following Cervical Laminoplasty.

scientific article

Metabolic Syndrome Components Are Associated with Intervertebral Disc Degeneration: The Wakayama Spine Study

scientific article published on 3 February 2016

MicroSEC filters sequence errors for formalin-fixed and paraffin-embedded samples

scientific article published on 15 December 2021

Midterm results of resection arthroplasty for forefoot deformities in patients with rheumatoid arthritis and the risk factors associated with patient dissatisfaction.

scientific article

Minimal clinically important differences in Toronto Extremity Salvage Score for patients with lower extremity sarcoma

scientific article published on 16 April 2019

Minimum clinically important difference in outcome scores among patients undergoing cervical laminoplasty

scientific article published on 14 March 2019

Missed Medial Malleolar Fracture Associated With Achilles Tendon Rupture: A Case Report and Literature Review

scientific article

Modulation of osteoclast function by adenovirus vector-induced epidermal growth factor receptor

scientific article published in November 1998

Molecular mechanisms underlying osteoarthritis development: Notch and NF-κB.

scientific article

Molecular understanding of pharmacological treatment of osteoporosis

scientific article published on 29 April 2019

Monokine induced by interferon-gamma is induced by receptor activator of nuclear factor kappa B ligand and is involved in osteoclast adhesion and migration

scientific article published on 7 December 2004

Mortality and morbidity after high-dose methylprednisolone treatment in patients with acute cervical spinal cord injury: a propensity-matched analysis using a nationwide administrative database.

scientific article published on 28 February 2013

Mortality and morbidity after spinal surgery in patients with Parkinson's disease: a retrospective matched-pair cohort study

scientific article published on 21 November 2016

Multi-layered PLLA-nanosheets loaded with FGF-2 induce robust bone regeneration with controlled release in critical-sized mouse femoral defects

scientific article published on 21 December 2018

Multidirectional wear and impact-to-wear tests of phospholipid-polymer-grafted and vitamin E-blended crosslinked polyethylene: a pilot study

scientific article published on March 2015

Multiple Acrometastases in a Patient with Renal Pelvic Urothelial Cancer.

scientific article published on 3 July 2017

Mutual associations among musculoskeletal diseases and metabolic syndrome components: A 3-year follow-up of the ROAD study

scientific article

Myositis ossificans after navigated knee surgery: A report of two cases and literature review.

scientific article published on 15 March 2016

NF-kappaB2 (p100) limits TNF-alpha-induced osteoclastogenesis

scientific article

Natural course and prognostic factors in patients with mild cervical spondylotic myelopathy with increased signal intensity on T2-weighted magnetic resonance imaging

scientific article published in October 2012

Necrotising soft-tissue infections of the upper limb: risk factors for amputation and death

scientific article published on November 2014

Negative feedback loop in the Bim-caspase-3 axis regulating apoptosis and activity of osteoclasts.

scientific article

Negative feedback loop of bone resorption by NFATc1-dependent induction of Cadm1.

scientific article

Negative regulation of BMP/Smad signaling by Tob in osteoblasts

scientific article (publication date: 22 December 2000)

Negative regulation of osteoclastogenesis by ectodomain shedding of receptor activator of NF-kappaB ligand

scientific article published on 03 October 2006

Neutrophil CD64 expression as a diagnostic marker for local infection and crystal-induced arthritis

scientific article published on 15 June 2010

Neutrophil CD64 expression in the diagnosis of local musculoskeletal infection and the impact of antibiotics

scientific article published on 01 September 2009

New resorption assay with mouse osteoclast-like multinucleated cells formed in vitro ⬇️

scientific article published on August 1, 1993

New simulation model for bone formation markers in osteoporosis patients treated with once-weekly teriparatide

scientific article published on 23 December 2014

Nomogram predicting severe adverse events after musculoskeletal tumor surgery: analysis of a national administrative database

scientific article published on 7 May 2014

Opposing extracellular signal-regulated kinase and Akt pathways control Schwann cell myelination.

scientific article

Osteoclast differentiation by RANKL requires NF-kappaB-mediated downregulation of cyclin-dependent kinase 6 (Cdk6).

scientific article published on 24 May 2004

Osteoclasts express high levels of p60c-src, preferentially on ruffled border membranes

scientific article published in November 1992

Over-expression of integrin beta3 can partially overcome the defect of integrin beta3 signaling in transglutaminase 2 null macrophages.

scientific article

Overexpression of gamma-glutamyltransferase in transgenic mice accelerates bone resorption and causes osteoporosis

scientific article published on 15 March 2007

PEDF regulates osteoclasts via osteoprotegerin and RANKL

scientific article published on 27 November 2009

Parsing multiomics landscape of activated synovial fibroblasts highlights drug targets linked to genetic risk of rheumatoid arthritis

scientific article published on 02 November 2020

Partial functional recovery of paraplegic rat by adenovirus-mediated gene delivery of constitutively active MEK1.

scientific article

Patellar fracture after total knee arthroplasty for rheumatoid arthritis

scientific article published on 14 June 2012

Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis

scientific article published on 22 December 2013

Patient Satisfaction with Posterior Decompression Surgery for Cervical Ossification of the Posterior Longitudinal Ligament: Prognostic Radiographic Factors and Patient-Reported Outcomes for the Effectiveness of Surgical Treatment

scientific article published on 16 September 2016

Patient satisfaction with double-door laminoplasty for cervical compression myelopathy

scientific article published on 30 October 2014

Perioperative stroke in patients undergoing elective spinal surgery: a retrospective analysis using the Japanese diagnosis procedure combination database

scientific article published on 2 October 2015

Phase II/III, randomized, double-blind, parallel-group study of monthly delayed-release versus daily immediate-release risedronate tablets in Japanese patients with involutional osteoporosis

scientific article published on 16 August 2019

Phosphatidylinositol-3 kinase is involved in ruffled border formation in osteoclasts

scientific article published on 01 August 1997

Phosphorylated neurofilament subunit levels in the serum of cervical compressive myelopathy patients

scientific article published on 17 July 2015

Poly(2-methacryloyloxyethyl phosphorylcholine) grafting and vitamin E blending for high wear resistance and oxidative stability of orthopedic bearings

scientific article published on 15 May 2014

Possible involvement of focal adhesion kinase, p125FAK, in osteoclastic bone resorption

scientific article published in August 1995

Postmitotic osteoclast precursors are mononuclear cells which express macrophage-associated phenotypes

scientific article published on 01 May 1994

Postoperative outcomes of major lower extremity amputations in patients with diabetes and peripheral artery disease: analysis using the Diagnosis Procedure Combination database in Japan

scientific article published on 6 January 2016

Posttranslational regulation of Bim by caspase-3.

scientific article published on 21 June 2007

Potential involvement of p53 in ischemia/reperfusion-induced osteonecrosis

scientific article published on 01 November 2008

Prediction of proximal femur strength by a quantitative computed tomography-based finite element method--Creation of predicted strength data of the proximal femur according to age range in a normal population.

scientific article

Predictive Factors for Subjective Improvement in Lumbar Spinal Stenosis Patients with Nonsurgical Treatment: A 3-Year Prospective Cohort Study

scientific article published on 10 February 2016

Predictive factors for complications after surgical treatment for schwannomas of the extremities

scientific article published on 11 April 2019

Preparation and characterization of a mouse osteoclast-like multinucleated cell population

scientific article

Prevalence and co-existence of locomotive syndrome, sarcopenia, and frailty: the third survey of Research on Osteoarthritis/Osteoporosis Against Disability (ROAD) study

scientific article published on 20 June 2019

Prevalence and progression of radiographic ossification of the posterior longitudinal ligament and associated factors in the Japanese population: a 3-year follow-up of the ROAD study.

scientific article published on 22 August 2013

Prevalence of Facet Effusion and Its Relationship with Lumbar Spondylolisthesis and Low Back Pain: The Wakayama Spine Study

scientific article published on 31 December 2019

Prevalence of diffuse idiopathic skeletal hyperostosis (DISH) of the whole spine and its association with lumbar spondylosis and knee osteoarthritis: the ROAD study.

scientific article

Prevalence of hand osteoarthritis and its relationship to hand pain and grip strength in Japan: The third survey of the ROAD study

scientific article

Prevalence of joint replacement surgery in rheumatoid arthritis patients: cross-sectional analysis in a large observational cohort in Japan

scientific article

Prevalence of radiographic hip osteoarthritis and its association with hip pain in Japanese men and women: the ROAD study

scientific article published on August 2015

Prevalence of total knee arthroplasty and its predictive factors in Japanese patients with rheumatoid arthritis: Analysis using the NinJa cohort

scientific article published on 12 May 2015

Prevalence, incidence and progression of lumbar spondylosis by gender and age strata

scientific article published on 5 November 2013

Prevention of bacterial adhesion and biofilm formation on a vitamin E-blended, cross-linked polyethylene surface with a poly(2-methacryloyloxyethyl phosphorylcholine) layer

scientific article published on 4 June 2015

Pro-inflammatory cytokine tumor necrosis factor-alpha induces bone morphogenetic protein-2 in chondrocytes via mRNA stabilization and transcriptional up-regulation

scientific article published on 11 July 2006

Profiles of vitamin D insufficiency and deficiency in Japanese men and women: association with biological, environmental, and nutritional factors and coexisting disorders: the ROAD study

scientific article published on 15 May 2013

Prognostic factors associated with the surgical indication for lumbar spinal stenosis patients less responsive to conservative treatments: An investigator-initiated observational cohort study

scientific article published on 19 February 2017

Progression of ossification of the posterior longitudinal ligament of the thoracic spine following posterior decompression and stabilization

scientific article published on 15 August 2014

Progression, incidence, and risk factors for intervertebral disc degeneration in a longitudinal population-based cohort: the Wakayama Spine Study

scientific article published on 12 January 2017

Prophylactic effect of fondaparinux and enoxaparin for preventing pulmonary embolism after total hip or knee arthroplasty: A retrospective observational study using the Japanese Diagnosis Procedure Combination database

scientific article published on 11 February 2015

Prospective multicenter surveillance and risk factor analysis of deep surgical site infection after posterior thoracic and/or lumbar spinal surgery in adults.

scientific article published on November 2014

Protein kinase C zeta plays an essential role for Mycobacterium tuberculosis-induced extracellular signal-regulated kinase 1/2 activation in monocytes/macrophages via Toll-like receptor 2.

scientific article published on 22 August 2006

Psychometric Validation of the Japanese Version of the Neuropathic Pain Symptom Inventory

scientific article published on 24 November 2015

Pyogenic discitis due to Abiotrophia adiacens

scientific article published on 2 October 2013

Quadriceps muscle strength, radiographic knee osteoarthritis and knee pain: the ROAD study.

scientific article published on 16 October 2015

Quantitative and qualitative characterization of expanded CD4+ T cell clones in rheumatoid arthritis patients

scientific article

RANK-mediated amplification of TRAF6 signaling leads to NFATc1 induction during osteoclastogenesis.

scientific article published on 27 January 2005

RANKL as a therapeutic target of rheumatoid arthritis

scientific article published on 18 October 2020

RANKL is a therapeutic target of bone destruction in rheumatoid arthritis

scientific article published on 23 April 2019

RANKL-Independent Osteoclastogenesis: A Long-Standing Controversy

scientific article published on 17 February 2017

Real-world evidence of raloxifene versus alendronate in preventing non-vertebral fractures in Japanese women with osteoporosis: retrospective analysis of a hospital claims database.

scientific article published on 27 December 2016

Recalcitrant Lateral Premalleolar Bursitis of the Ankle Associated with Lateral Ankle Instability

scientific article published on 3 August 2017

Recent trends in orthopedic surgery performed in Japan for rheumatoid arthritis.

scientific article published on 24 February 2011

Reciprocal role of ERK and NF-kappaB pathways in survival and activation of osteoclasts

scientific article published on January 2000

Reconstruction Using Frozen Autograft for Disseminated Phosphaturic Mesenchymal Tumor of the Humerus after a Pathological Fracture

scientific article published on 04 September 2019

Recurrent hemarthrosis after total knee arthroplasty caused by the impingement of a remnant lateral meniscus: a case report

scientific article published on 31 October 2013

Regulation of Chondrocyte Survival in Mouse Articular Cartilage by p63.

scientific article published on 28 October 2016

Regulation of RANKL-induced osteoclastogenesis by TGF-β through molecular interaction between Smad3 and Traf6.

scientific article published on July 2011

Regulation of bone destruction in rheumatoid arthritis through RANKL-RANK pathways ⬇️

scientific article published on January 18, 2013

Regulation of bone resorption and sealing zone formation in osteoclasts occurs through protein kinase B-mediated microtubule stabilization

scientific article published in May 2013

Regulation of cytochrome c oxidase activity by c-Src in osteoclasts

scientific article

Regulation of mouse chondrocyte differentiation by CCAAT/enhancer-binding proteins.

scientific article published on January 2015

Regulation of osteoclast apoptosis and motility by small GTPase binding protein Rac1.

scientific article published on 22 August 2005

Regulation of osteoclast apoptosis by Bcl-2 family protein Bim and Caspase-3.

scientific article published in January 2010

Regulation of osteoclast apoptosis by ubiquitylation of proapoptotic BH3-only Bcl-2 family member Bim.

scientific article published on December 2003

Relationship Between Pain Reduction and Improvement in Health-Related Quality of Life in Patients with Knee Pain Due to Osteoarthritis Receiving Duloxetine: Exploratory Post Hoc Analysis of a Japanese Phase 3 Randomized Study

scientific article published on 20 January 2020

Relationship between roentgenographic joint destruction in the hands and functional disorders among patients with rheumatoid arthritis.

scientific article published on 10 November 2016

Repeated total en bloc spondylectomy for spinal metastases at different sites in one patient

scientific article published on 01 July 2015

Rheumatoid arthritis associated with osteopetrosis

scientific article published on 06 August 2009

Risk Factors for Prolonged Treatment of Whiplash-Associated Disorders.

scientific article published on 6 July 2015

Risk factors affecting inhospital mortality after hip fracture: retrospective analysis using the Japanese Diagnosis Procedure Combination Database.

scientific article

Risk factors for falls in a longitudinal population-based cohort study of Japanese men and women: the ROAD Study

scientific article published on 24 October 2012

Risk factors for pulmonary embolism and the effects of fondaparinux after total hip and knee arthroplasty: a retrospective observational study with use of a national database in Japan

scientific article

Risk of infectious complications associated with blood transfusion in elective spinal surgery-a propensity score matched analysis.

scientific article published on 20 October 2015

Risks of in-hospital death and complications after fusion surgery in patients with atlantoaxial subluxation: analysis of 1090 patients using the Japanese Diagnosis Procedure Combination database

scientific article published on 18 December 2014

Runx1 contributes to articular cartilage maintenance by enhancement of cartilage matrix production and suppression of hypertrophic differentiation

scientific article published on 21 May 2019

S100A1 and S100B are dispensable for endochondral ossification during skeletal development.

scientific article published on January 2014

SOX10 transactivates S100B to suppress Schwann cell proliferation and to promote myelination

scientific article

Scientific basis for the efficacy of combined use of antirheumatic drugs against bone destruction in rheumatoid arthritis

scientific article published on 20 February 2007

Sclerostin: from bench to bedside

scientific article published on 18 November 2020

Secondary Chondrosarcoma Presenting with Symptoms Similar to Thoracic Outlet Syndrome.

scientific article published on 12 March 2018

Secure fixation of femoral bone plug with a suspensory button in anatomical anterior cruciate ligament reconstruction with bone-patellar tendon-bone graft

scientific article published on July 2015

Segregation of TRAF6-mediated signaling pathways clarifies its role in osteoclastogenesis

scientific article published on March 2001

Serum levels of 25-hydroxyvitamin D and the occurrence of musculoskeletal diseases: a 3-year follow-up to the road study

scientific article published on 20 August 2014

Serum levels of matrix metalloproteinase-3 and autoantibodies related to rheumatoid arthritis in the general Japanese population and their association with osteoporosis and osteoarthritis: the ROAD study.

scientific article published in April 2017

Signal transduction pathways regulating osteoclast differentiation and function ⬇️

scientific article published on January 1, 2003

Simple and Robust Differentiation of Human Pluripotent Stem Cells toward Chondrocytes by Two Small-Molecule Compounds

scientific article published on 08 August 2019

Skeletal-related events and prognosis in urothelial cancer patients with bone metastasis

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Smad4 is required to inhibit osteoclastogenesis and maintain bone mass

scientific article published on 12 October 2016

Spinal cord swelling in patients with cervical compression myelopathy

scientific article published on 14 June 2019

Statistics for orthopedic surgery 2006-2007: data from the Japanese Diagnosis Procedure Combination database

scientific article published in March 2010

Stenosing Tenosynovitis of the Flexor Hallucis Longus Tendon Associated with the Plantar Capsular Accessory Ossicle at the Interphalangeal Joint of the Great Toe.

scientific article published on 31 January 2017

Successful Treatment of Atlantoaxial Subluxation in an Adolescent Patient with BrachytelephalangicChondrodysplasia Punctata

scientific article published on 27 January 2019

Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction

scientific article published on 6 November 2006

The Association between the Cross-Sectional Area of the Dural Sac and Low Back Pain in a Large Population: The Wakayama Spine Study

scientific article

The Japanese version of the STarT Back Tool predicts 6-month clinical outcomes of low back pain

scientific article published on 23 December 2016

The Serum Phosphorylated Neurofilament Heavy Subunit as a Predictive Marker for Outcome in Adult Patients after Traumatic Brain Injury

scientific article published on 20 April 2016

The association of combination of disc degeneration, end plate signal change, and Schmorl node with low back pain in a large population study: the Wakayama Spine Study

scientific article published on 27 November 2014

The crucial role of Erk2 in demyelinating inflammation in the central nervous system

scientific article published on 05 September 2016

The effect of cartilage degeneration on ultrasound speed in human articular cartilage

scientific article published on 3 November 2015

The effect of switching from teriparatide to anti-RANKL antibody on cancellous and cortical bone in ovariectomized mice

scientific article

The effects of presence of a backside screw hole on biotribological behavior of phospholipid polymer-grafted crosslinked polyethylene

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The impact of joint disease on the Modified Health Assessment Questionnaire scores in rheumatoid arthritis patients: A cross-sectional study using the National Database of Rheumatic Diseases by iR-net in Japan

scientific article published on 20 November 2015

The mid-term efficacy of intra-articular hyaluronic acid injections on joint structure: a nested case control study

scientific article published on 23 August 2012

The prevalence of tandem spinal stenosis and its characteristics in a population-based MRI study: The Wakayama Spine Study

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The relationship between findings on magnetic resonance imaging and previous history of low back pain

scientific article published on 29 December 2016

The role of medial meniscus posterior root tear and proximal tibial morphology in the development of spontaneous osteonecrosis and osteoarthritis of the knee

scientific article published on 3 February 2017

The usefulness of neutrophil CD64 expression in the diagnosis of local infection in patients with rheumatoid arthritis in daily practice

scientific article published in July 2010

The utility of 25-question Geriatric Locomotive Function Scale for evaluating functional ability and disease activity in Japanese rheumatoid arthritis patients: A cross-sectional study using NinJa database

scientific article published on 18 April 2018

Thoracic intradural extramedullary lesions causing progressive myelopathy as an initial manifestation of granulomatosis with polyangiitis: a case report and review of literature

scientific article published on 22 April 2016

Three-dimensional fluoroscopic navigation guidance for femoral tunnel creation in revision anterior cruciate ligament reconstruction

scientific article published on 15 June 2012

Tiludronate inhibits protein tyrosine phosphatase activity in osteoclasts

scientific article published in May 1997

Time trends and risk factors for perioperative complications in total ankle arthroplasty: retrospective analysis using a national database in Japan

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Total Hip Arthroplasty in a Patient with Oto-Spondylo-Megaepiphyseal Dysplasia Planned by Three-Dimensional Motion Analyses and Full-Scale Three-Dimensional Plaster Model of Bones.

scientific article

Total hip arthroplasty after rotational acetabular osteotomy

scientific article published on 8 October 2014

Traf6 is essential for murine tooth cusp morphogenesis

scientific journal article

Transcription factor Hes1 modulates osteoarthritis development in cooperation with calcium/calmodulin-dependent protein kinase 2.

scientific article

Treatment of spinal cord injury by an advanced cell transplantation technology using brain-derived neurotrophic factor-transfected mesenchymal stem cell spheroids.

scientific article

Twice cutting method reduces tibial cutting error in unicompartmental knee arthroplasty

scientific article published on 7 December 2014

Tyrosine phosphorylation and translocation of the c-cbl protein after activation of tyrosine kinase signaling pathways

scientific article published on 01 June 1995

Ultrasonographic evaluation of displaced neurovascular bundle in Dupuytren disease.

scientific article published on 4 December 2012

Urinary 8-iso-prostaglandin F2α as a marker of metabolic risks in the general Japanese population: The ROAD study

scientific article published on 7 June 2015

Usefulness of QuickDASH in patients with cervical laminoplasty

scientific article published on 06 January 2014

Validation study of a diagnostic scoring system for sacroiliac joint-related pain

scientific article published on 28 August 2018

Validity and reliability of the Japanese version of the painDETECT questionnaire: a multicenter observational study

scientific article

Vertebral fractures affect functional status in postmenopausal rheumatoid arthritis patients

scientific article published on 21 December 2013

Wear resistance of poly(2-methacryloyloxyethyl phosphorylcholine)-grafted carbon fiber reinforced poly(ether ether ketone) liners against metal and ceramic femoral heads

scientific article published on 9 May 2017

Wortmannin, a specific inhibitor of phosphatidylinositol-3 kinase, blocks osteoclastic bone resorption

scientific article published in March 1995

Wrist Arthrodesis in Rheumatoid Arthritis Using an LCP Metaphyseal Locking Plate versus an AO Wrist Fusion Plate

scientific article published on 10 July 2018

c-Cbl is downstream of c-Src in a signalling pathway necessary for bone resorption.

scientific article

tPA activates LDL receptor-related protein 1-mediated mitogenic signaling involving the p90RSK and GSK3beta pathway

scientific article

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